222-OR: High Glucose Level Increases Expression of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Receptors

To interact glucose level of blood with finger biting was the goal of present research. 130 subjects took part in present research, where their glucose level of blood calculated. The normal glucose level in blood is in between 100 to 140mg/dl. The hyperglycemia is known as high glucose level while hypoglycemia is known as low glucose level. The biting of fingers in the mouth with teeth is known as finger biting. It also refer as onychophagia. There were 130 students take part in this research and they measured their sugar level by using glucose meter. Then they correlate the glucose level with finger biting. It was concluded from the present study that glucose level of blood has no impact on finger biting.

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Role of SGLT1 in high glucose level-induced MMP-2 expression in human cardiac fibroblasts

Molecular Medicine Reports ◽

10.3892/mmr.2018.8688 ◽

2018 ◽

Cited By ~ 1

Author(s):

Liping Meng ◽

Hiroyasu Uzui ◽

Hangyuan Guo ◽

Hiroshi Tada

Keyword(s):

Glucose Level ◽

High Glucose ◽

Cardiac Fibroblasts ◽

High Glucose Level ◽

Human Cardiac Fibroblasts

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A diterpene derivative enhanced insulin signaling induced by high glucose level in HepG2 cells

Journal of Natural Medicines ◽

10.1007/s11418-019-01384-7 ◽

2020 ◽

Vol 74 (2) ◽

pp. 434-440

Author(s):

Peilei Hou ◽

Yanbo Qu ◽

Zhixin Liao ◽

Shifeng Zhao ◽

Yan Feng ◽

...

Keyword(s):

Glucose Level ◽

Insulin Signaling ◽

High Glucose ◽

Hepg2 Cells ◽

High Glucose Level

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Gambaran Faktor Risiko dan Tipe Stroke pada Pasien Rawat Inap di Bagian Penyakit Dalam RSUD Kabupaten Solok Selatan Periode 1 Januari 2010 - 31 Juni 2012

Jurnal Kesehatan Andalas ◽

10.25077/jka.v2i2.119 ◽

2013 ◽

Vol 2 (2) ◽

pp. 57

Author(s):

Cintya Agreayu Dinata ◽

Yuliarni Safrita Safrita ◽

Susila Sastri

Keyword(s):

Risk Factors ◽

Risk Factor ◽

Ischemic Stroke ◽

Glucose Level ◽

High Glucose ◽

Hemorrhagic Stroke ◽

Secondary Data ◽

Modifiable Risk Factors ◽

Stroke Patients ◽

High Glucose Level

AbstrakStroke merupakan penyakit akibat gangguan peredaran darah otak yang dipengaruhi oleh banyak faktor risiko terdiri dari yang tidak dapat diubah berupa usia dan jenis kelamin dan yang dapat diubah seperti hipertensi, peningkatan kadar gula darah, dislipidemia, dan pekerjaan. Penelitian ini bertujuan untuk mengetahui distribusi tipe stroke dan faktor risiko yang berpengaruh pada pasien stroke rawat inap di RSUD Kabupaten Solok Selatan. Metode penelitian: Penelitian ini adalah penelitian deskriptif dengan menggunakan data skunder pasien stroke yang dirawat di RSUD Solok Selatan. Data yang diambil meliputi usia, jenis kelamin, tekanan darah, kadar gula darah, profil lipid saat pertama pasien masuk rumah sakit, dan pekerjaan. Sampel penelitian adalah seluruh pasien stroke yang pernah dirawat di Bagian Penyakit Dalam RSUD Kabupaten Solok Selatan pada periode 1 Januari 2010 – 31 Juni 2012 yang memenuhi kriteria inklusi. Hasil penelitian: Hasil penelitian menunjukkan proporsi stroke terbanyak adalah stroke ischemic (61,46%), perempuan (54,17%) yang berusia >50 tahun (81,25%) yang bekerja sebagai ibu rumah tangga (43,75%). Faktor risiko yang dapat diubah tertinggi adalah hipertensi (82,30%) diikuti kolesterol total meningkat (69,79%). Faktor risiko tertinggi pada stroke ischemic adalah gula darah meningkat (47,89%) dan pada stroke hemorrhagic adalah hipertensi (100,00%). Faktor risiko tertinggi pada seluruh pasien adalah hipertensi (82,30%). Kesimpulan: Berdasarkan hasil penelitian ini disimpulkan bahwa stroke tipe ischemic lebih banyak dari tipe hemorrhagic dengan faktor risiko utama hipertensi, sedangkan stroke ischemic terutama dipengaruhi oleh peningkatan gula darah.Kata kunci: stroke ischemic, stroke hemorrhagic, faktor risiko strokeAbstractStroke is a disease caused by disorder of brain blood circulation with many risk factors that contribute in this disease, consist of non modifiable risk factor including age and sex and modifiable risk factors example hypertension, high glucose level, dyslipidemia, and jobs. This study aimed to determine the distribution of the type of stroke and the risk factors that affect to stroke patients who were treat in South Solok hospital.Methods: This research is descriptive research using secondary data, including the patient’s medical record. The data including age, gender, blood pressure, glucose level, lipid profile when the first patient in the hospital, and jobs. The samples were all stroke patients who had been treat in the Department of Internal Medicine of South Solok hospital in the period from January 1st 2010 until June 31th 2012 that meet the inclusion criteria.The results: The results showed the highest proportion of strokes were ischemic stroke (61.46%), women (54.17%) aged> 50 years (81.25%) who work as housewives (43.75%). The highest of modifiable risk factors are hypertension (82.30%) followed by increases in total cholesterol (69.79%). The highest risk factors for ischemic stroke is high glucose level (47.89%) and for hemorrhagic stroke is hypertension (100.00%). The highest risk in both ischemic stroke and hemorrhagic is hypertension (82.30%).Conclusion: Based on the end result, we can concluded that the insidence of ischemic stroke disease is greater than hemorrhagic stroke, and as the main risk factor is hypertension, mean while ischemic stroke is most affected by high glucose level.Keywords: stroke ischemic, stroke hemorrhagic, faktor risiko stroke

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492: Effect of high glucose level on the function of human 3D cardiac micro-tissues derived from induced pluripotent stem cells

American Journal of Obstetrics and Gynecology ◽

10.1016/j.ajog.2016.11.227 ◽

2017 ◽

Vol 216 (1) ◽

pp. S290-S291

Author(s):

Michael Balistreri ◽

Justin A. Davis ◽

Andre Monteiro da Rocha ◽

Katherine F. Campbell ◽

Marjorie C. Treadwell ◽

...

Keyword(s):

Stem Cells ◽

Induced Pluripotent Stem Cells ◽

Glucose Level ◽

Pluripotent Stem Cells ◽

High Glucose ◽

High Glucose Level ◽

Induced Pluripotent

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Differential responses of bone to angiotensin II and angiotensin(1-7): beneficial effects of ANG(1-7) on bone with exposure to high glucose

AJP Endocrinology and Metabolism ◽

10.1152/ajpendo.00158.2020 ◽

2021 ◽

Vol 320 (1) ◽

pp. E55-E70

Author(s):

Nan-Nan Sha ◽

Jia-Li Zhang ◽

Christina Chui-Wa Poon ◽

Wen-Xiong Li ◽

Yue Li ◽

...

Keyword(s):

Angiotensin Ii ◽

Glucose Level ◽

High Glucose ◽

Raw 264.7 Cells ◽

Raw 264.7 ◽

Ang Ii ◽

Mineral Density ◽

High Glucose Condition ◽

High Glucose Level ◽

Glucose Condition

Osteoporosis, diabetes, and hypertension are common concurrent chronic disorders. This study aimed to explore the respective effects of angiotensin II (ANG II) and angiotensin(1-7) [ANG(1-7)], active peptides in the renin-angiotensin system, on osteoblasts and osteoclasts under high-glucose level, as well as to investigate the osteo-preservative effects of ANG II type 1 receptor (AT1R) blocker and ANG(1-7) in diabetic spontaneously hypertensive rats (SHR). ANG II and ANG(1-7), respectively, decreased and increased the formation of calcified nodules and alkaline phosphatase activity in MC3T3-E1 cells under high-glucose level, and respectively stimulated and inhibited the number of matured osteoclasts and pit resorptive area in RANKL-induced bone marrow macrophages. Olmesartan and Mas receptor antagonist A779 could abolish those effects. ANG II and ANG(1-7), respectively, downregulated and upregulated the expressions of osteogenesis factors in MC3T3-E1 cells. ANG II promoted the expressions of cathepsin K and MMP9 in RAW 264.7 cells, whereas ANG(1-7) repressed these osteoclastogenesis factors. ANG II rapidly increased the phosphorylation of Akt and p38 in RAW 264.7 cells, whereas ANG(1-7) markedly reduced the phosphorylation of p38 and ERK under high-glucose condition. After treatments of diabetic SHR with valsartan and ANG(1-7), a significant increase in trabecular bone area, bone mineral density, and mechanical strength was only found in the ANG(1-7)-treated group. Treatment with ANG(1-7) significantly suppressed the increase in renin expression and ANG II content in the bone of SHR. Taken together, ANG II/AT1R and ANG(1-7)/Mas distinctly regulated the differentiation and functions of osteoblasts and osteoclasts upon exposure to high-glucose condition. ANG(1-7) could protect SHR from diabetes-induced osteoporosis.

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