scholarly journals Skeletal Muscle Microvascular-Linked Improvements in Glycemic Control From Resistance Training in Individuals With Type 2 Diabetes

Diabetes Care ◽  
2017 ◽  
Vol 40 (9) ◽  
pp. 1256-1263 ◽  
Author(s):  
Ryan D. Russell ◽  
Donghua Hu ◽  
Timothy Greenaway ◽  
Sarah J. Blackwood ◽  
Renee M. Dwyer ◽  
...  
2018 ◽  
Vol 10 (2) ◽  
pp. 331-338 ◽  
Author(s):  
Eri Takenami ◽  
ShinMin Iwamoto ◽  
Noriko Shiraishi ◽  
Akiko Kato ◽  
Yuichi Watanabe ◽  
...  

2020 ◽  
Vol 8 (1) ◽  
pp. e001027 ◽  
Author(s):  
Tomonori Kimura ◽  
Takuro Okamura ◽  
Keiko Iwai ◽  
Yoshitaka Hashimoto ◽  
Takafumi Senmaru ◽  
...  

ObjectiveReduction of muscle mass and strength is an important treatment target for patients with type 2 diabetes. Recent studies have reported that high-intensity resistance training improves physical function; however, all patients found it difficult to perform high-intensity resistance training. Radio calisthenics, considered as therapeutic exercises to promote health in Japan, are simple exercises that can be performed regardless of age and help move the muscles and joints of the whole body effectively according to the rhythm of radio. We investigated the efficacy of radio calisthenics for muscle mass in patients with type 2 diabetes in this retrospective cohort study.Research design and methodsA total of 42 hospitalized patients with type 2 diabetes were recruited. The skeletal muscle mass index (SMI, kg/m2) was calculated as appendicular muscle mass (kg) divided by height squared (m2). We defined the change of SMI as the difference of SMI between the beginning and end of hospitalization.ResultsAmong 42 patients, 15 (11 men and 4 women) performed radio calisthenics. Body weights of both radio calisthenics exercisers and non-exercisers decreased during hospitalization. The change of SMI was significantly lesser in radio calisthenics exercisers than in non-exercisers (7.1±1.4 to 7.1±1.3, –0.01±0.09 vs 6.8±1.1 to 6.5±1.2, –0.27±0.06 kg/m2, p=0.016). The proportion of decreased SMI was 85.2% (23/27 patients) in non-radio calisthenics exercisers, whereas that in radio calisthenics exercisers was 46.7% (7/15 patients).ConclusionsRadio calisthenics prevent the reduction of skeletal muscle mass. Thus, radio calisthenics can be considered effective for patients with type 2 diabetes.


Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2636 ◽  
Author(s):  
Leslie A. Consitt ◽  
Courtney Dudley ◽  
Gunjan Saxena

Aging is associated with insulin resistance and the development of type 2 diabetes. While this process is multifaceted, age-related changes to skeletal muscle are expected to contribute to impaired glucose metabolism. Some of these changes include sarcopenia, impaired insulin signaling, and imbalances in glucose utilization. Endurance and resistance exercise training have been endorsed as interventions to improve glucose tolerance and whole-body insulin sensitivity in the elderly. While both types of exercise generally increase insulin sensitivity in older adults, the metabolic pathways through which this occurs can differ and can be dependent on preexisting conditions including obesity and type 2 diabetes. In this review, we will first highlight age-related changes to skeletal muscle which can contribute to insulin resistance, followed by a comparison of endurance and resistance training adaptations to insulin-stimulated glucose metabolism in older adults.


Diabetes Care ◽  
2006 ◽  
Vol 29 (12) ◽  
pp. 2586-2591 ◽  
Author(s):  
D. W. Dunstan ◽  
E. Vulikh ◽  
N. Owen ◽  
D. Jolley ◽  
J. Shaw ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Raza Qadir ◽  
Nicholas F. Sculthorpe ◽  
Taylor Todd ◽  
Elise C. Brown

Abstract Background Resistance training (RT) is an effective intervention for glycemic control and cardiometabolic health in individuals with type 2 diabetes (T2D). However, the use of RT in individuals at risk for T2D to prevent or delay the onset of T2D, and RT program characteristics that are most effective are still unknown. The purpose of this review is to determine the effects of RT on cardiometabolic risk factors in those at risk for T2D and to examine RT program characteristics associated with intervention effectiveness. Methods PubMed, Cochrane, Web of Science, and Embase databases were systematically searched for published controlled trials that compared cardiometabolic outcomes in adults with cardiometabolic risk for those that underwent an RT intervention with those that did not. A systematic review and meta-analysis was conducted to determine the effect of RT on glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), body fat percentage (BF%), total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and triglycerides (TG). Additional analyses examined effects of intervention duration and dietary intervention on FPG and TG. Results Fourteen trials with 668 participants were included. For RT compared to controls, the standardized mean difference (SMD) was −1.064 for HbA1c (95% confidence interval [CI] −1.802 to −0.327; p=0.005), −0.99 for FPG (95% CI −1.798 to −0.183; p=0.016), −0.933 for TC (95% CI −1.66 to −0.206; p=0.012), −0.840 for BF% (95% CI −1.429 to −0.251; p=0.005), −0.693 for HDL (95% CI −1.230 to −0.156; p=0.011), −1.03 for LDL (95% CI −2.03 to −0.050; p=0.039), and −0.705 for TG (95% CI −1.132 to −0.279; p=0.001). Conclusions RT is beneficial for improving glycemic control, BF%, and blood lipids in those at risk for diabetes. The addition of a dietary component did not result in larger reductions in FPG and TG than RT alone. PROSPERO Registration ID CRD42019122217


Author(s):  
Karina Rodionova ◽  
Aija Kļaviņa

Type 2 diabetes (T2D) comprises 90% of people with diabetes around the world, and is largely the result of excess body weight and physical inactivity (WHO, 2015). Objective: To evaluate and analyze evidence based research studies exploring the impact of physical activity on health variables in elderly population age 50-70 years with T2D.Data sources: Web of Science, CINAHL, SCOPUS, EMBASE, MEDLINE, PubMed and SPORTdiscus data bases were used for screening and selecting relevant research studies over the period 2005-2015.Study Selections: Randomized controlled trials (RCTs). Population: older adults or elderly with T2D. Intervention: All types of physical activity such as interval walking, aquatics or free living activity were included. Outcomes: glycemic control, lipid profile, insulin sensitivity, BMI, blood pressure and VO₂max. Methodological quality was assessed using the Delphi List.Data Synthesis: While 1773 potentially relevant studies were found and 213 RCTs were relevant to the topic, only 16 studies (patients n= 946) accepted to the review. Results: The circuit resistance training was associated with hemoglobin A1c (HbA1c) decrease (8.0 (.35) to 7.36 (.28)), body mass index (BMI) reduction from 22.0(.8) to 20.9 (.8) and body weight change from 53.3 (1.6) to 51.9 (1.7). Improvement of insulin sensitivity, VO2max and glycemic control were observable in 8 studies including 16-week aerobic exercise training, 16-week interval walking training, and combined aerobic and resistance training. Combination of aerobic and resistance exercises were associated with positive change in plasma fasting glucose and were 6.86 (1.40) and 6.19 (1.47).Conclusions: The most effective and time consuming physical activity is interval walking, circuit training or combination of different intensity and/or physical activity modalities.


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