scholarly journals Differential Correlation between Foetal Haemoglobin and Full Blood Count Based on Inherited Haemoglobin Type; A Cross-Sectional Study in Cape Coast, Ghana

2018 ◽  
Vol 2 (2) ◽  
Author(s):  
Patrick Adu
Keyword(s):  
Blood Count ◽  
Type A ◽  
Cross Sectional Study ◽  
Full Blood Count ◽  
Foetal Haemoglobin ◽  
Sectional Study ◽  
Cape Coast ◽  
Cross Sectional ◽  
Differential Correlation ◽  
Haemoglobin Type

scholarly journals Prevalence, characteristics and risk factors of imported and local malaria cases in North-Western Province, Zambia: a cross-sectional study

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Maureen N. Chipoya ◽  
Nzooma M. Shimaponda-Mataa
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Malaria Prevalence ◽  
Imported Malaria ◽  
Full Blood Count ◽  
Sectional Study ◽  
Cross Sectional ◽  
Western Province ◽  
Imported Cases ◽  
North Western

Abstract Background Imported malaria is a major challenge for countries that are in malaria elimination stage such as Zambia. Legitimate cross-border activities add to the risk of transmission, necessitating determination of prevalence, characteristics and risk factors of imported and local malaria. Methods This cross-sectional study was conducted in 103 consented child and adult patients with clinical malaria symptoms, from selected health facilities in north-western Zambia. Patient demographic data and blood samples for malaria microscopy and full blood count were obtained. Chi-square and penalized logistic regression were performed to describe the characteristics and assess the risk factors of imported and local malaria in North-Western Province. Results Overall, malaria prevalence was 78.6% with 93.8% Plasmodium falciparum and 6.2% other species. The local cases were 72 (88.9%) while the imported were 9 (11.1%) out of the 81 positive participants. About 98.6% of the local cases were P. falciparum compared to 55.6% (χ2 = 52.4; p < 0.01) P. falciparum among the imported cases. Among the imported cases, 44% were species other than P. falciparum (χ2 = 48; p < 0.01) while among the local cases only 1.4% were. Gametocytes were present in 44% of the imported malaria cases and only in 2.8% of the local cases (χ2 = 48; p < 0.01). About 48.6% of local participants had severe anaemia compared to 33.3% of participants from the two neighbouring countries who had (χ2 = 4.9; p = 0.03). In the final model, only country of residence related positively to presence of species other than P. falciparum (OR = 39.0, CI [5.9, 445.9]; p < 0.01) and presence of gametocytes (OR = 23.1, CI [4.2, 161.6]; p < 0.01). Conclusion Malaria prevalence in North-Western Province is high, with P. falciparum as the predominant species although importation of Plasmodium ovale and Plasmodium malariae is happening as well. Country of residence of patients is a major risk factor for malaria species and gametocyte presence. The need for enhanced malaria control with specific focus on border controls to detect and treat, for specific diagnosis and treatment according to species obtaining, for further research in the role of species and gametocytaemia in imported malaria, cannot be overemphasized.

scholarly journals Hematologic Abnormalities in Treatment-naïve HIV Patients

2010 ◽  
Vol 3 ◽  
pp. IDRT.S6033 ◽  
Author(s):  
Akinsegun Akinbami ◽  
Olajumoke Oshinaike ◽  
Titilope Adeyemo ◽  
Adewunmi Adediran ◽  
Owolabi Dosunmu ◽  
...  
Keyword(s):  
Blood Count ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Hiv Treatment ◽  
University Teaching ◽  
Full Blood Count ◽  
Hiv Patients ◽  
Cross Sectional ◽  
Treatment Naïve ◽  
Pre Treatment

Objectives Hematologic abnormalities, indicated by a deranged full blood count, are common manifestations and important prognostic tools for human immunodeficiency virus (HIV) infection and AIDS. This study aimed to determine the prevalence of cytopenia and its relationship to the degree of immunosupression in HIV treatment-naïve patients. Methods This was a cross-sectional study of treatment-naïve HIV-infected clients who enrolled at the HIV clinic of Lagos State University Teaching Hospital (LASUTH) between December 2009 and June 2010. Participants had samples taken for full blood count and CD4 counts, which are free routine pre-requisite and pre-treatment evaluations done for all registered HIV patients at LASUTH. They were asked to fill the structured questionnaires to obtain demographic data, with assistance if necessary. Results A total of 205 cases were reviewed: 24.2% had anemia (PCV < 30%), 26.8% had leucopenia (white blood cell <4,000/L) and 16.1% had thrombocytopenia (platelet count <150,000/L) at enrollment. The degree of cytopenia was directly related to the degree of immunosupression. Conclusion About one-fifth of HIV treatment-naïve patients were cytopenic at enrollment and the degree of cytopenia was directly related to the degree of immunosupression. It is necessary to investigate various causes of cytopenia in these patients so as to administer a specific intervention.

scholarly journals CORRELATION BETWEEN WDF, WNR, AND RET ABNORMAL SCATTERGRAM DETECTED BY SYSMEX XN-1000 AND PARASITEMIA OF MALARIA PATIENTS IN MERAUKE HOSPITAL

2019 ◽  
Vol 26 (1) ◽  
pp. 91
Author(s):  
Merylin Ranoko ◽  
Aryati Aryati ◽  
Arifoel Hajat
Keyword(s):  
General Hospital ◽  
Health Problem ◽  
Gold Standard ◽  
Blood Count ◽  
Complete Blood Count ◽  
Cross Sectional Study ◽  
Response To Therapy ◽  
Sectional Study ◽  
Cross Sectional ◽  
Degree Of Severity

Malaria remains a health problem in Indonesia. Microscopic examination with Giemsa staining is the gold standard for diagnosing malaria. The density of parasites correlates with the degree of severity and response to therapy of malaria. Malaria-causing plasmodium can be detected by Sysmex XN-1000 which is marked by abnormalities in the WDF, WNR and RET scattergram. This research aimed to determine the correlation of WDF, WNR and RET abnormal scattergram detected by Sysmex XN-1000 and the parasitemia index of malaria at the Merauke General Hospital. This was a cross-sectional study with observational approach conducted between November 2017 – February 2018 at the Merauke General Hospital. Positive malaria samples were stained with Giemsa, their parasitemia index was calculated, routine complete blood count using Sysmex XN-1000 was performed, and the scattergram abnormalities were then analyzed. There were 65 positive malaria samples as follows: P.falciparum (35%), P.vivax (60%), P.ovale (3.1%), and P.malariae (1.5%), but the species did not correlate with parasitemic index (p=0.691). Abnormalities of WDF and WNR scattergram were predominantly found than RET scattergram (80% vs. 27.7%). P.vivax predominantly caused abnormalities of the WDF and WNR scattergram in 36 of 39 samples (92.3%), whereas P.falciparum predominantly caused abnomalities of the RET scattergram in 14 of 23 samples (60.9%). There was 95% positivity of an abnormality in WDF/WNR/RET scattergram with a cut-off of > 5,0165.5/µL. There was correlation between WDF, WNR, RET scattergram detected by Sysmex XN-1000 and the parasitemia index.

scholarly journals Microcytic and Malarial Anaemia Prevalence in Urban Children ≤15 Years in the Mount Cameroon Area: A Cross-Sectional Study on Risk Factors

Anemia ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-12
Author(s):  
Sharon Odmia Sama ◽  
Seraphine Njuontsop Chiamo ◽  
Germain Sotoing Taiwe ◽  
Gwendolyne Elobe Njume ◽  
Irene Ule Ngole Sumbele
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Cross Sectional Study ◽  
Health Concern ◽  
Full Blood Count ◽  
Sectional Study ◽  
Microcytic Anaemia ◽  
Cross Sectional ◽  
Mount Cameroon ◽  
Child Age

Background. Anaemia, a common nutritional deficiency, is a public health problem in the Mount Cameroon area. This study determined the prevalence and possible risk factors of microcytic and malarial anaemia in children less than ≤15 years residing in the Buea and Limbe municipalities in the Mount Cameroon area. Methods. A total of 566 children were clinically examined in a cross-sectional study from December 2018 to August 2019 for anaemia and malaria parasites. Blood samples collected were used in evaluating full blood count with the aid of an automated haemoanalyser, and malaria parasite was confirmed by microscopy. Anaemia was defined based on WHO standards while microcytic anaemia and malarial anaemia were defined as microcytosis + anaemia and malaria + anaemia, respectively. Factors that showed significance in the bivariate analysis were entered into a multinomial logistic regression to determine risk factors for microcytic and malarial anaemia. Results. The overall prevalence for anaemia, microcytosis, microcytic anaemia, and malarial anaemia was, respectively, 68.7%, 48.9%, 36.9%, and 19.6% with microcytic anaemia representing 53.7% of all anaemic cases. Risk factors for microcytic anaemia included child age of 1–5 years P = 0.007 , forest ethnicity P = 0.019 , parents being farmers P = 0.038 or jobless P = 0.009 , and having moderate malaria parasitaemia P = 0.048 while those for malarial anaemia were child age of 6–10 years P = 0.008 , parents’ age of 26–35 years P = 0.049 , parents being jobless P = 0.023 , and consuming plantains 3-4 times P = 0.024 a week. Conclusion. Microcytic anaemia is getting to be a severe public health concern while malarial anaemia is a mild public health issue in children residing in urban areas of Mount Cameroon. Parents’ occupation was directly linked to all anaemia forms; hence, any intervention to curb anaemia should consider aspects that will raise the socioeconomic status of the population.

scholarly journals Reduced Haematopoietic Output in Automobile Mechanics and Sprayers with Chronic Exposure to Petrochemicals: A Case-Control Study in Cape Coast, Ghana

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Patrick Adu ◽  
Richard Pobee ◽  
Aaron Awuah ◽  
Paul B. Asiamah ◽  
Festus Amoani ◽  
...  
Keyword(s):  
Occupational Safety ◽  
Reticulocyte Count ◽  
Venous Blood ◽  
Safety Information ◽  
Cross Sectional Study ◽  
Safety Training ◽  
Full Blood Count ◽  
Cape Coast ◽  
Cross Sectional ◽  
Indirect Measure

Background. Automobile mechanics and sprayers are at a higher risk of exposure to hazardous chemicals such as polycyclic aromatic hydrocarbons and heavy metals which may cause adverse health outcomes. This study aimed to use reticulocyte count as an indirect measure of the haematological output in automobile mechanics and sprayers in the Cape Coast Metropolis, Ghana. Method. This cross-sectional study recruited 130 participants: 90 cases (57 automobile mechanics and 33 automobile sprayers) and 40 controls (nonautomobile workers). Venous blood samples were drawn from the participants and examined for full blood count and absolute reticulocyte count. Semi-structured questionnaire was used to collect demographic and occupational safety information from participants. Results. 75.6% of cases had never received occupational safety training. Whereas 35.1% of automobile mechanics routinely siphoned fuel, 36.4% of automobile sprayers never used nose masks in the discharge of their duties. Controls had significantly higher WBC counts compared to mechanics (p=0.0001; 5.04±1.7 versus 3.81±1.1), or sprayers (p=0.0004; 5.04±1.7 versus 3.74±0.9). Lymphocyte, monocyte, and platelet counts were also significantly higher in controls compared to cases. Whereas RBC counts were significantly higher in controls compared to automobile mechanics (4.85 versus 4.66; p=0.034), haemoglobin levels were significantly higher in automobile sprayers compared to controls (15.13 versus 14.1 g/dl; p=0.0126). Absolute reticulocyte count was significantly higher in controls compared to cases [p<0.0001; (56.88±32.14) × 109/L (controls) versus (25.31±15.75) × 109/L (sprayers) or (33.27±24.42) × 109/L (mechanics)]. Among the cases however, only RBC counts were significantly lower in automobile mechanics compared to automobile sprayers (p=0.0088; 4.66±0.4 versus 4.85±0.5). Conclusion. It was evident that both automobile mechanics and sprayers had significantly reduced haematopoietic output. Occupational safety training is not given priority and must be addressed.

scholarly journals RELATIONSHIP BETWEEN ESOPHAGITIS GRADES AND HELICOBACTER PYLORI

2016 ◽  
Vol 29 (3) ◽  
pp. 135-137 ◽  
Author(s):  
Patrícia Fernanda Saboya RIBEIRO ◽  
Luiz Fernandao KUBRUSLY ◽  
Paulo Afonso Nunes NASSIF ◽  
Irma Cláudia Saboya RIBEIRO ◽  
Andressa de Souza BERTOLDI ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Type A ◽  
Cross Sectional Study ◽  
Endoscopic Examination ◽  
Type B ◽  
Gastric Lesions ◽  
Sectional Study ◽  
Cross Sectional ◽  
Urease Test ◽  
Significant Difference

ABSTRACT Background: The Helicobacter pylori infection (HP) is related to the development of gastric lesions and lymphoma; however, it is not known if there is a relation with gastroesophageal reflux disease and reflux esophagitis. Aim: To evaluate HP's relationship with esophagitis in patients undergoing upper endoscopy. Methods: Observational, retrospective and cross-sectional study, being evaluated 9576 patients undergoing outpatient endoscopic examination during the period between January and December 2015. Were included patients with any esophageal alteration at the examination; greater than 18; of both genders; independent of the complaint or the reason for the examination, illness or drug use. Were excluded those with active bleeding during the examination and in use of anticoagulants. The variables gender, age, esophagitis and result of the urease test, were studied. For statistical analysis was used the Epi Info software 7.1.5.2. Results: Most of the samples consisted of women and the overall average age was 46.54±16.32 years. The presence of infection was balanced for gender: 1204 (12.56%) women and 952 (13.92%) men. Relating degree of esophagitis HP- and HP+ was observed that the type A was the most common (58.79%, n=1460); 604 (24.32%) had grade B; 334 (13.45%) grade C, and 85 (3.42%) grade D. In the relation between the grade of esophagitis with gender, esophagitis A was predominant in women and present in 929 (63.33%), followed by type B, 282 (46.68%), 136 C (40.71%) and D 30 (35.29%). In men 531 (36.36%) showed type A, 322 (53.31%) B, 198 (59.28%) C, and 55 (64.70%) D. Among the groups 40-50 and over 60 years there was a significant difference in whether have or not have HP+. Conclusion: There is no significant difference between HP infection and the different grades of esophagitis.

Sign in / Sign up

Export Citation Format

Share Document