ANEURYSMAL BONE CYST (ABC) IN FIFTH METACARPAL RIGHT HAND OF A MALE CHILD WITH HEMOPHILIA TREATED BY STEROID INJECTION: A CASE REPORT

ABSTRACTAneurysma bone cyst (ABC) is a rare case, rapidly growing, and destructive benign bone tumor that rarely involves the bones of the hand. Pathogenesis of these tumors remains controversial and may be vascular, traumatic, or genetic disorders. This study aimed to evaluate patient’s out come after steroid injection. A male child presented with a history of pain and local swelling over his fifth metacarpal right hand of two months duration with hemofilia condition. Physical and radiographic examination of the hand was consistent with aneurysmal bone cyst. The patient the VIII factor 2 hours before doing steroid injection on his lump over fifth metacarpal right hand. A month evaluation after injection for this patient, we had a good result clinically and radiologically. Radiological evaluation obtained appearance of cortex thickening on the bone affected. We concluded that steroid injection should be considered as one of ABC’s treatment with hemophilia, but the outcome still needed more evaluation. Keywords: Aneurysmal Bone Cyst, Hemophilia, Steroid Injection ABSTRAK Kista tulang aneurisma adalah kasus yang jarang terjadi, tumbuh dengan cepat, dan tumor tulang jinak destruktif yang jarang melibatkan tulang-tulang tangan. Patogenesis tumor ini masih kontroversial dan mungkin bersifat kelainan vaskular, traumatis, atau genetik. Penelitian ini bertujuan untuk mengevaluasi pasien setelah injeksi steroid. Seorang anak laki-laki dengan riwayat nyeri dan pembengkakan lokal pada metacarpal kelima tangan kanannya selama dua bulan dengan kondisi hemofilia. Pemeriksaan fisik dan radiografi tangan menegakkan adanya kista tulang aneurisma. Pasien diberi faktor VIII 2 jam sebelum injeksi steroid pada benjolan di atas metacarpal kelima tangan kanannya. Evaluasi sebulan setelah injeksi untuk pasien ini, kami memiliki hasil yang baik secara klinis dan radiologis. Evaluasi radiologis diperoleh penampilan penebalan korteks pada tulang yang terkena. Kami menyimpulkan bahwa injeksi steroid harus dipertimbangkan sebagai salah satu pengobatan kista tulang aneurisma dengan hemofilia, namun hasilnya masih perlu evaluasi lebih lanjut.Kata kunci: Kista Tulang Aneurisma, Hemofilia, Injeksi steroid

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Traumatic bone cyst of mandible: a case series

Journal of Medical Case Reports ◽

10.1186/s13256-019-2220-7 ◽

2019 ◽

Vol 13 (1) ◽

Cited By ~ 1

Author(s):

Farnoosh Razmara ◽

Zahra Ghoncheh ◽

Ghazal Shabankare

Keyword(s):

Bone Cyst ◽

Clinical Signs ◽

Case Series ◽

Signs And Symptoms ◽

Radiographic Examination ◽

Radiographic Evaluation ◽

History Of ◽

Mandibular Region ◽

Clinical Signs And Symptoms ◽

Anterior Mandible

Abstract Background A traumatic bone cyst is an uncommon nonneoplastic lesion of the jaws that is considered as a “pseudocyst” because of the lack of an epithelial lining. This lesion is particularly asymptomatic and therefore is diagnosed by routine dental radiographic examination as a unilocular radiolucency with scalloped borders, mainly in the posterior mandibular region. The exact etiopathogenesis of the lesion remains uncertain, though it is often associated with trauma. Case presentation We report three Persian cases of traumatic bone cyst with different clinical and radiographic features, and we present a review of the literature to further discuss diagnostic and treatment challenges. Only one of the three patients reported a history of trauma, and despite the usual signs and symptoms of the lesion, extension of the defect to the ramus, swelling of the lingual cortex, and their unusual presence in the anterior mandible were noted in these patients. Conclusions Because features of this cyst can be varied, careful history taking and radiographic evaluation alongside the clinical signs and symptoms have a very significant role in definitive diagnosis, appropriate treatment, and accurate assessment of prognosis.

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Aneurysmal bone cyst of the spine

The Journal of Laryngology & Otology ◽

10.1258/0022215054273052 ◽

2005 ◽

Vol 119 (6) ◽

pp. 495-497 ◽

Cited By ~ 5

Author(s):

C E B Giddings ◽

D Bray ◽

S Stapleton ◽

H Daya

Keyword(s):

Differential Diagnosis ◽

Aneurysmal Bone Cyst ◽

Osteolytic Lesion ◽

Bone Cyst ◽

Treatment Modalities ◽

Open Resection ◽

Cervical Trauma ◽

Radiographic Appearance ◽

Posterior Triangle ◽

History Of

The authors present the case of an 11-year-old boy with a painful, rapidly expanding lesion in the posterior triangle of the neck. There was no history of cervical trauma. Computerized tomography of the neck revealed a unicameral (single-chambered) aneurysmal bone cyst involving the C3 vertebra. Treatment was by open resection and curettage; no recurrence was seen at six months. We discuss the natural history, differential diagnosis, radiographic appearance and treatment modalities for this unusual, benign, expanding, osteolytic lesion containing blood-filled cystic cavities.

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CISTO ÓSSEO SIMPLES - RELATO DE CASO CLÍNICO

Journal of Dentistry & Public Health ◽

10.17267/2596-3368dentistry.v5i3.445 ◽

2015 ◽

Vol 5 (3) ◽

Author(s):

Anne Lopes Oliveira ◽

Jandson Michel Santos ◽

Adriano Assis ◽

Sílvia Regina de Almeida Reis ◽

Alena Peixoto Medrado

Keyword(s):

Bone Cyst ◽

Excisional Biopsy ◽

World Health ◽

Radiographic Examination ◽

Simple Bone Cyst ◽

Neoplastic Lesion ◽

Left Mandible ◽

History Of ◽

Health Organization ◽

Pain Symptoms

The World Health Organization classifies simple bone cyst as a non-neoplastic lesion related to bones, defined as an intraosseous cyst, which features a thin capsule. Its etiology remains unknown, and the most accepted explanation is related to the history of trauma. It is in most cases clinically asymptomatic and the diagnosis is often established through routine radiographic examination. The objective of this study is to report a case of a simple bone cyst in the left mandible region in a young patient underwent imaging examinations for follow-up orthodontic treatment.The patient attended the Maxillofacial Traumatology Surgery Service showing circumscribed unilocular radiolucent lesion, in the left mandible region.Reported no significant swelling or pain symptoms. Excisional biopsy was performed and histopathological findings showed bone tissue associated with a thin membrane of connective tissue, and absence of epithelial lining. Today, after two years of surgical treatment, there is no evidence of recurrence.

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Classic Adamantinoma with Osteofibrous Dysplasia-like Foci and Secondary Aneurysmal Bone Cyst

Pediatric and Developmental Pathology ◽

10.1007/s10024-002-8812-y ◽

2003 ◽

Vol 6 (2) ◽

pp. 173-178 ◽

Cited By ~ 3

Author(s):

Angelica Putnam ◽

Suzanne Yandow ◽

Cheryl M. Coffin

Keyword(s):

Aneurysmal Bone Cyst ◽

Unusual Case ◽

Bone Cyst ◽

Bone Lesion ◽

Giant Cells ◽

Multinucleated Giant Cells ◽

Osteofibrous Dysplasia ◽

Pathologic Features ◽

History Of ◽

Secondary Aneurysmal Bone Cyst

Adamantinoma, a rare bone lesion of the tibia and fibula, has two distinct variants, classic adamantinoma and osteofibrous dysplasia-like adamantinoma. Composite lesions have not been described. Aneurysmal bone cyst is a benign cystic lesion which may also occur in the tibia and fibula. We report an unusual case of classic adamantinoma with osteofibrous dysplasia-like areas and foci of secondary aneurysmal bone cyst with prominent giant cells. A lesion was diagnosed in a 17-year-old girl with a 14-year history of a slowly enlarging left tibial mass and increasing deformity. Pathologically, the predominant pattern was classic adamantinoma, with minor foci of osteofibrous dysplasia-like adamantinoma and areas of secondary aneurysmal bone cyst with abundant multinucleated giant cells. We report the clinical, radiologic, and pathologic features of this case, and summarize lesions associated with secondary aneurysmal bone cyst. To our knowledge, the association of adamantinoma with secondary aneurysmal bone cyst has not been previously reported.

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Complicated aneurysmal bone cyst of the paranasal sinuses in a 9-year-old child

Health and Ecology Issues ◽

10.51523/2708-6011.2021-18-3-19 ◽

2021 ◽

pp. 152-158

Author(s):

E. S. Yadchenko ◽

I. D. Shlyaga ◽

D. D. Radzko ◽

A. V. Novik

Keyword(s):

Medical History ◽

Paranasal Sinuses ◽

Aneurysmal Bone Cyst ◽

Clinical Case ◽

Clinical Observation ◽

Bone Cyst ◽

Morphological Studies ◽

History Of ◽

Immunohistochemical Methods ◽

One Year

Objective. To analyze a rare clinical case of the aneurysmal bone cyst (ABC) of the paranasal sinuses in a 9-year-old patient.Materials and methods. We studied the data of the anamnesis, diagnostic and treatment methods contained in the medical history of the inpatient. We examined the patient and kept her under clinical observation during the process of the examination and treatment.Results. The fnal diagnosis of the ABC of the paranasal sinuses in the 9-year-old patient was verifed after the obtainment of the results of the performed clinical and morphological studies. The neoplasm was surgically removed. One year after the surgery, the MRI investigation showed no relapse. The child is in a fair condition.Conclusion. To diagnose an ABC, it is required to perform a histological examination of the tumor including the use of immunohistochemical methods.

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Dedifferentiated Liposarcoma of the Retroperitoneum With Heterologous Osteosarcomatous Differentiation and a Striking Aneurysmal Bone Cyst–Like Morphology

International Journal of Surgical Pathology ◽

10.1177/1066896917693093 ◽

2017 ◽

Vol 25 (4) ◽

pp. 374-378 ◽

Cited By ~ 1

Author(s):

Carole Van Haverbeke ◽

Jo Van Dorpe ◽

Evelyne Lecoutere ◽

Uta Flucke ◽

Liesbeth Ferdinande ◽

...

Keyword(s):

Aneurysmal Bone Cyst ◽

Clinical Presentation ◽

Histopathological Examination ◽

Bone Cyst ◽

Dedifferentiated Liposarcoma ◽

Resected Specimen ◽

Retroperitoneal Mass ◽

Mdm2 Gene ◽

History Of ◽

Mdm2 Overexpression

A 69-year-old woman with a 10-year medical history of recurrent retroperitoneal dedifferentiated liposarcoma presented with a 3-cm large hemorrhagic and multicystic left-sided retroperitoneal mass. Histopathological examination of the resected specimen showed a heterogeneous, high-grade mesenchymal nonlipogenic tumor with areas of osteoblastic/osteosarcomatous differentiation and aneurysmal bone cyst–like features. Based on the clinical presentation, the morphology, and the supportive immunohistochemical and molecular findings (MDM2 overexpression and amplification of the MDM2 gene, respectively), a diagnosis of a dedifferentiated liposarcoma with heterologous osteosarcomatous differentiation and an aneurysmal bone cyst–like morphology was made. To the best of our knowledge, this is the first description of aneurysmal bone cyst–like morphology in dedifferentiated liposarcoma, further expanding the broad morphological spectrum of dedifferentiated liposarcoma.

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Primary telangiectatic osteosarcoma of the cervical spine

Journal of Neurosurgery Spine ◽

10.3171/2011.12.spine111037 ◽

2012 ◽

Vol 16 (4) ◽

pp. 373-378 ◽

Cited By ~ 4

Author(s):

Mazda K. Turel ◽

Vivek Joseph ◽

Vandita Singh ◽

Vinu Moses ◽

Vedantam Rajshekhar

Keyword(s):

Cervical Spine ◽

Aneurysmal Bone Cyst ◽

Histopathological Examination ◽

Bone Cyst ◽

Biological Behavior ◽

Adjuvant Radiation ◽

Diagnostic Challenge ◽

Telangiectatic Osteosarcoma ◽

History Of ◽

Glue Embolization

Telangiectatic osteosarcoma (TOS) is one of the 8 subtypes of osteosarcoma that infrequently affects the spine. The radiopathological features of TOS overlap with those of more benign entities, most commonly the aneurysmal bone cyst), and therefore is a significant diagnostic challenge. It is a rare but well-described entity in the thoracolumbar and sacral spine, and to the authors' knowledge has not been previously reported in the cervical spine. The authors report the case of a 15-year-old boy who presented with a 6-month history of neck pain and torticollis. He underwent preoperative glue embolization followed by a staged subtotal C-5 spondylectomy and posterior fusion for a C-5 vertebral body lytic expansile lesion. Histopathological examination showed the lesion to be TOS. The surgery was followed by adjuvant radiation and chemotherapy with a favorable outcome at the 1-year follow-up. This report reiterates that TOS is an important differential diagnosis for aneurysmal bone cyst and giant-cell tumor of the spine, as its biological behavior and clinical outcome differ from those of these more benign lesions, which it mimics.

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Aneurysmal Bone Cyst of Clavicle in a Six-Year-Old Male Child

Journal of Medical Research and Innovation ◽

10.15419/jmri.80 ◽

2017 ◽

Vol 1 (3) ◽

pp. 31-36

Author(s):

Rushin P. Patel ◽

Shakti Goel ◽

Pankaj R. Patel

Keyword(s):

Aneurysmal Bone Cyst ◽

Bone Cyst ◽

Needle Aspiration ◽

Male Child ◽

Lower Limbs ◽

Excision Biopsy ◽

Left Shoulder ◽

Long Bones ◽

First Case ◽

Needle Aspiration Cytology

Aneurysmal Bone Cyst (ABCs) is a cystic expansile lesion which is usually found in solitary locations in the metaphysis of long bones. The most common locations of ABC are long bones of lower limbs. There is little knowledge about the presence of this tumor in Clavicle. Here we present a case of a six year old male child who presented with complaint of swelling in left shoulder for four months. There was a dilemma in the diagnosis of the swelling due to its unusual presentation and appearance. The Fine Needle Aspiration Cytology was also inconclusive. The diagnosis of ABC was made only by excision biopsy. The Clavicle regenerated to nearly normal anatomy at 15 weeks follow up period. The patient is asymptomatic now and is able to perform all daily activities without any restrictions. The uniqueness of this case lies in the fact that this is the first case where ABC has been reported in Clavicular region in young Asian male of less than 10 years age. Keywords: ABC, Bone tumor, Expansile lesion.

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