IMPACT OF CARDIOGEN INJECTION IN THE ADRENALINE-INDUCED STRESS MODEL ON THE RATE OF THE HEART INDEX AND WEIGHTED PARAMETERS OF RAT BODIES

2020 ◽  
Author(s):  
A.M. Mendzheritckiy ◽  
◽  
A.N. Vovk ◽  
N.S. Isachkina ◽  
D.S. Medvedev ◽  
...  
Keyword(s):  
Heart Rate ◽  
Adrenal Glands ◽  
Relative Mass ◽  
Stress Model ◽  
Reduce Heart Rate ◽  
Induced Stress

The article presents the results of a study of the effect of Cardiogen on changes in heart rate and weight parameters of organs under stress in rats. The introduction of Cardiogen compensates for the stressful effect of adrenaline on the change in the relative mass of the heart, adrenal glands and spleen. Cardiogen also helps reduce heart rate to control values and manifestations of arrhythmia under stress.

Haemodynamic Effects of Different Beta Blockers in Angina Pectoris

1977 ◽  
Vol 22 (1) ◽  
pp. 64-68 ◽  
Author(s):  
H. Åström ◽  
B. Jonsson
Keyword(s):  
Heart Rate ◽  
Angina Pectoris ◽  
Stroke Volume ◽  
Partial Agonist ◽  
Beta Blockers ◽  
Haemodynamic Effects ◽  
Agonist Activity ◽  
Peripheral Vascular ◽  
Reduce Heart Rate ◽  
Beta Blocking

Beta-blocking agents with partial agonist activity seem to reduce heart rate at rest slightly less than those without this property. Cardio-selective drugs have no effect on stroke volume at rest contrary to the non-selective ones which will reduce it somewhat. This difference is abolished during exercise. The only difference seen during work between different beta-blockers is the effect on the peripheral vascular resistance. The selective drugs lower the arterial pressure with unchanged resistance.

An Objective Method of Assessing a Stress Syndrome Related to Achievement Motivation

1964 ◽  
Vol 19 (1) ◽  
pp. 183-197 ◽  
Author(s):  
J. Warren Thiesen ◽  
Ronald H. Forgus ◽  
Fred E. Spaner
Keyword(s):  
Heart Rate ◽  
Achievement Motivation ◽  
Heart Rate Response ◽  
Test Procedure ◽  
Objective Method ◽  
Psychosomatic Disorders ◽  
Initial Experiment ◽  
Induced Stress ◽  
Stress Syndrome ◽  
Speed And Accuracy

An approach to the definition and assessment of a stress syndrome related to achievement motivation is described. Because of the importance it has assumed in some recent psychosomatic hypotheses and because of its broader implications for personality theory and research, a relatively simple and objective means of measuring the intensity of stress referable to this syndrome seemed necessary. Toward this end a standard psychophysiological test procedure was devised. The method yields objective measures of degree and duration of heart-rate elevation in response to tasks emphasizing speed and accuracy pressures. An initial experiment demonstrated the validity of some theoretical constructs underlying the procedure. A retest study demonstrated its replicability and its potential for measuring adaptation to stress. The results indicate that the sustained heart-rate response, as utilized in this procedure, is a sensitive and convenient measure of stress associated with achievement motivation. It is suggested that the test battery and methodology described may be useful in research concerning striving-induced stress and its role in psychosomatic disorders.

Adrenal contribution to cardiac responses elicited by acute hypoxia in piglets

1980 ◽  
Vol 239 (6) ◽  
pp. H751-H755 ◽  
Author(s):  
J. C. Lee ◽  
J. C. Werner ◽  
S. E. Downing
Keyword(s):  
Heart Rate ◽  
Adrenal Glands ◽  
Acute Hypoxia ◽  
Cardiac Contractility ◽  
Sympathetic Nerves ◽  
Left Ventricular ◽  
Cardiac Work ◽  
Ganglionic Blockade ◽  
Cardiac Responses

The adrenal contribution to cardiac responses elicited by acute hypoxia was assessed in 16 piglets, 1-12 wks old, anesthetized with pentobarbital (30 mg/kg). External cardiac work was held constant and parasympathetic blockade was produced in each animal with atropine (1 mg). Hypoxia was produced by addition of N2 to the respirator. In a sham-adrenalectomy group (n = 6) left ventricular (LV) dP/dtmax increased significantly during hypoxia (PaO2 approximately 30 mmHg) to 3,680 +/- 414 mmHg/s from control values of 2,686 +/- 317 mmHg/s (P < 0.01). Heart rate rose from 171 +/- 6 to 186 +/- 7 beats/min (P < 0.02). These responses were not significantly altered by ganglionic blockade with trimethaphan camsylate (0.5 mg x kg-1 x min-1). Equally large increases of LV dP/dtmax appeared when heart rate was held constant by pacing. beta-Adrenoreceptor blockade with practolol (4 mg/kg) sharply reduced but did not eliminate the response. In contrast, no changes in LV dP/dtmax or heart rate were observed during hypoxia in adrenalectomized piglets (n = 6). These findings indicate that the increased cardiac contractility during acute hypoxia in piglets is dependent on the integrity of the adrenal glands and that there is minimal contribution from cardiac sympathetic nerves.

Propranolol in Experimentally Induced Stress

1981 ◽  
Vol 139 (6) ◽  
pp. 545-549 ◽  
Author(s):  
Elizabeth A. Taylor ◽  
Paul Turner ◽  
Jean Harrison
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Oral Dose ◽  
Systolic Blood Pressure ◽  
Healthy Volunteers ◽  
The Self ◽  
Experimental Stress ◽  
Double Blind ◽  
Beta Adrenoceptor ◽  
Induced Stress

SummaryThe influence of beta-adrenoceptor antagonism on the effects of a simple experimental stress was investigated in 12 healthy volunteers, using a double-blind protocol. A single oral dose of 80 mg propranolol reduced the stress-induced increase in heart rate and systolic blood pressure to 49.9 per cent and 8.3 per cent respectively compared to 61.0 per cent and 17.4 per cent with placebo. The rise in diastolic blood pressure was small and unaffected by beta-adrenoceptor blockade. The rise in temperature of the skin of the trunk was significantly reduced by propranolol. The self-rating of anxiety, alertness and concentration by the subjects was unaffected by propranolol.

TSV Induced Stress Model and Its Application in Delay Estimation

2018 ◽  
Author(s):  
Raghav Chawla ◽  
Sarita Yadav ◽  
Arvind Sharma ◽  
Baljit Kaur ◽  
Rajendra Pratap ◽  
...  
Keyword(s):  
Delay Estimation ◽  
Stress Model ◽  
Induced Stress

Adaptation to physical training in rats orally supplemented with glycerol

2015 ◽  
Vol 93 (1) ◽  
pp. 63-69 ◽  
Author(s):  
Eric Francelino Andrade ◽  
Raquel Vieira Lobato ◽  
Ticiana Vasques de Araújo ◽  
Débora Ribeiro Orlando ◽  
Diego Vicente da Costa ◽  
...  
Keyword(s):  
Physical Training ◽  
Aspartate Aminotransferase ◽  
Adrenal Mass ◽  
Adrenal Glands ◽  
Male Rats ◽  
Relative Mass ◽  
Exercise Session ◽  
Performance Parameters ◽  
Neutrophil Lymphocyte Ratio ◽  
Lactate Levels

We evaluated training adaptation and physical performance parameters in rats orally supplemented with glycerol, glucose, or saline, and submitted to moderate aerobic exercise. Thirty male rats were trained for 6 weeks and administered the supplements during the last 4 weeks of the experiment. Animals were distributed in a completely randomized factorial 2 × 3 design (with or without exercise and 3 substrates). Data were subjected to analysis of variance (ANOVA) and means were compared using the Student–Newmann–Keuls test at 5%. Among the trained animals, none of the substances caused differences in the percentages of protein, fat, or water content in the carcass. Compared with the sedentary animals, the trained animals supplemented with saline and glucose showed a higher protein percentage in the carcass. The relative mass of the heart and adrenal glands was higher in the trained animals. Glycerol improved the protein content in non-trained animals and increased the relative adrenal mass in both groups. Glycerol reduced the variation in levels of lactate and aspartate aminotransferase (AST) during the last exercise session. There was no difference between groups regarding the relative mass of the thymus and gastrocnemius or with the diameter of muscle fibers or the neutrophil–lymphocyte ratio. Supplementation with glycerol was efficient at attenuating variation in AST and lactate levels during exercise.

Interactions of Marijuana and Induced Stress: Forearm Blood Flow, Heart Rate, and Skin Conductance

1976 ◽  
Vol 13 (6) ◽  
pp. 517-522 ◽  
Author(s):  
Bruce D. Naliboff ◽  
William H. Rickles ◽  
Michael J. Cohen ◽  
Robert S. Naimark
Keyword(s):  
Heart Rate ◽  
Blood Flow ◽  
Skin Conductance ◽  
Forearm Blood Flow ◽  
Induced Stress

LOW DOSES OF CAFFEINE REDUCE HEART RATE DURING SUBMAXIMAL CYCLE ERGOMETRY

2003 ◽  
Vol 35 (Supplement 1) ◽  
pp. S277
Author(s):  
S R. McClaran ◽  
T J. Wetter ◽  
J R. Kruger ◽  
J D. Ewoldt
Keyword(s):  
Heart Rate ◽  
Cycle Ergometry ◽  
Low Doses ◽  
Reduce Heart Rate
Sign in / Sign up

Export Citation Format

Share Document