scholarly journals Side Effect Profile of COVID-19 Vaccine among Health Workers in a Tertiary Health Institution in South-South Nigeria

2021 ◽  
Vol 3 (3) ◽  
pp. 59-64
Author(s):  
Peter C. Oriji ◽  
Dennis O. Allagoa ◽  
Lukman Obagah ◽  
Obielumani I. Oguche ◽  
Onyekachi S. Ohaeri ◽  
...  

Background: Side effect following vaccination usually ranges from mild to moderate and occasionally severe in a small proportion of people. Covid-19 vaccine is no exception as side effects have been reported which are mostly mild to moderate and transient. The chances of any of these side effect following vaccination differ according to the specific COVID-19 vaccine. Objective: To determine the side effect profile of the Health workers that received the COVID-19 vaccination in the Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria. Materials and Method: This study was a descriptive cross-sectional study. It was carried out between 15th and 30th April 2021 among 151 health workers that received COVID-19 vaccination in the Federal Medical Centre, Yenagoa, Bayelsa State, Nigeria. The data were collected with a predesigned questionnaire and were analysed using IBM SPSS 23.0 version. Results: About 52.3% were female health workers, 49.0% were aged between 36–45 years. Side effects were reported in 9 of every 10 health workers who received the vaccine. Most side effects (53.0%) started on the day of vaccination. The most common side effect was pain at the injection site, and it was reported by 104 recipients of the vaccine (68.9%). Fever, headache, tiredness and chills were reported in 57.0%, 49.0%, 47.7% and 43.7%, respectively. Conclusion: As with medications and other vaccines, COVID-19 vaccines have side effects. Protective immunity against COVID-19 is developed following vaccination. In the face of a still rapidly evolving situation, what seems obvious is that vaccination currently remains the best route to achieving herd immunity.

2021 ◽  
Vol 14 (10) ◽  
pp. 1049
Author(s):  
Abanoub Riad ◽  
Andrea Pokorná ◽  
Jitka Klugarová ◽  
Natália Antalová ◽  
Lucia Kantorová ◽  
...  

Young adults had been widely perceived as a low-risk group for COVID-19 severity; therefore, they were deprioritised within the mass vaccination strategies as their prognosis of COVID-19 infection is relatively more favourable than older age groups. On the other hand, vaccination of this demographic group is indispensable to achieve herd immunity. A cross-sectional survey-based study was used to evaluate the side effects of mRNA-based COVID-19 vaccines among university students in the Czech Republic. The validated questionnaire was delivered in a digital form, and it consisted of demographic data; COVID-19 vaccine-related anamnesis; and local, systemic, orofacial, and skin-related side effects’ prevalence, onset, and duration. Out of the 539 included participants, 70.1% were females and 45.8% were <23 years old. The vast majority (95.2%) reported at least one side effect. The most common side effect was injection site pain (91.8%), followed by fatigue (62.5%), headache (36.4%), and muscle pain (34.9%). The majority of local side effects occurred after both doses (74.4%), while most systemic side effects occurred after the second dose only (56.2%). Most local (94.2%) and systemic (93.3%) side effects resolved within three days after vaccination. Females participants’ adjusted odds ratio (AOR) showed they were 2.566 (CI 95%: 1.103–5.970) times more likely to experience post-vaccination side effects, and the participants who received two doses reported an increased AOR of 1.896 (0.708–5.077) for experiencing side effects. The results of this study imply that mRNA-based COVID-19 vaccines are highly probably safe for young adults, and further studies are required to investigate the role of medical anamnesis, prior COVID-19 infection, and gender in side effects incidence.


2020 ◽  
Vol 42 (3) ◽  
pp. 887-894
Author(s):  
Ayesha Yasmeen ◽  
Mamoon H. Syed ◽  
Abdulkarim M. Meraya ◽  
Ahmed A. Albarraq ◽  
Hafiz A. Makeen ◽  
...  

2019 ◽  
Vol 10 (3) ◽  
pp. 163-171
Author(s):  
Indah Purnama Sari ◽  
Dewi Handayani ◽  
Fatmalina Febry

Exclusive breastfeeding is one of the successful indicators in improving the health of babies. From 2013 until 2014, the practice of exclusive breastfeeding has decreased in Indonesia and has not reached the national targets of around 80% of babies being exclusively breastfed. This study aimed to identify the prevalence and determinants of exclusive breastfeeding in Seberang Ulu I, Palembang. A community-based cross sectional study was executed from July 5, 2016 to August 5, 2016 among mothers who had infants aged less than six months. A purposive sampling technique was used to select a sample of 125 participants. Data were collected using a structured questionnaire by the face-to-face interview technique. Bivariate and multiple logistic regression analysis were used to determine factors associated with the practice of breastfeeding exclusively and to control confounding effects. The prevalence of exclusive breastfeeding was 26.4% (95% CI: 20.0%-35.1%). After adjusting for confounders (mothers’ attitudes and health workers’ support), mothers who had good knowledge were 11.66 times more likely to breastfeed exclusively than those who had poor knowledge (AOR: 11.66, 95% CI: 3.07-44.31). The prevalence of exclusive breastfeeding in Seberang Ulu I, Palembang, was still very low and has not reached the national target. The recommendation is to maximize the role of health workers in providing information about exclusive breastfeeding, so that they can continue providing motivation for mothers, husbands and families, so that the success and sustainability of exclusive breastfeeding practices could be achieved.   Keywords: Mother’s knowledge, mother’s attitude, health workers support, exclusive breastfeeding


2017 ◽  
Vol 11 ◽  
pp. 117955811771301 ◽  
Author(s):  
Tameh Theodore Yangsi ◽  
Fouelifack Ymele Florent ◽  
Mbong Eta Ngole ◽  
Fomulu Nelson

Background: To understand the low modern contraceptive prevalence in Cameroon, we reviewed the methods chosen and determined their side effects among patients in an urban setting. Methods: We conducted a cross-sectional study at the “Cameroon National Planning Association for Family Welfare (CAMNAFAW) Clinic” in Yaoundé. Data were processed by SPSS software version 20.0 for Windows, and all tests were considered statistically significant at P < .05. Results: Of the 1180 women sampled, the most chosen methods were as follows: depot medroxy progesterone acetate: 72.1% (787 of 1091), followed by oral combined contraceptives: 21.3% (232 of 1091), subcutaneous implants: 3.2% (35 of 1091), and intrauterine contraceptive devices: 1.9% (21 of 1091). A hundred and forty two (14.5%) of the 977 women received at least once (revisits) at the Center, reported at least one side effect. Irregular vaginal bleeding was the most frequent side effect: 44.6% (84 of 188 total documented side effects). Side effects were most common among users of subcutaneous implants: 28% (7 of the 25 implant users). Conclusions: Prescription of contraceptives should reflect not only the desire of couples but also the side effects associated with each method. This would optimize observance and adherence, consequently decreasing the failure rate.


2018 ◽  
Vol 7 (1-2) ◽  
pp. 9-12
Author(s):  
Prasanna Ghimire ◽  
Dwight Koirala ◽  
Bhuvaneswor Prasad Singh

Introduction: Radiological investigations form a cornerstone in the management of patients. Patient might me unware of the radiation exposure. The aim of this study is to assess patient’s knowledge of radiation exposure to common diagnostic imaging procedures.Methods: A cross-sectional study was conducted and questionnaire used to collect data from 216 patients who had undergone radiological investigations.Results: Among 216 patients, there were 112 (51.85 %) females and 104 (48.15 %) males. The age of the patients ranged from 12 years to 66 years. Only 65 patients (30.1 %) were aware of the radiation hazards. Neoplasm was the most common side effect chosen by 60 patients. 44 patients were informed of radiation hazards with only 17 patients however informed by the referring doctor. Patients having undergone radiological procedure previously were more aware of radiation hazards (21 patients out of 26 patients).Conclusion: This study showed dearth of knowledge and awareness regarding radiation hazards amongst general public which mandates education.


Author(s):  
Aditi Tiwari ◽  
Satnam Kaur ◽  
Rani Gera

Introduction: There is scarcity of Paediatric literature regarding local side effects of Inhaled Corticosteroids (ICSs) and available paediatric literature on the subject is old and has shown variable prevalence of these side effects varying from none to 60%. Aim: To evaluate local side effects of inhaled Budesonide in asthmatic children of ≤12 years. Materials and Methods: In this cross-sectional study, 250 asthmatic children attending Paediatric chest clinic of a tertiary care hospital and taking inhaled Budesonide for at least three months were evaluated for occurrence of local side effects during preceding one month. Local side effects (dysphonia, sore throat, cough during inhalation, thirsty feeling after inhalation, oral ulcers) experienced in preceding month were asked for and clinical evaluation for oral thrush, perioral dermatitis and tongue hypertrophy was done at the time of assessment. Information was collected regarding potential risk factors associated with occurrence of these side effects. Chi-square test was used to study the association between qualitative variables. Univariate and multivariate logistic regression were used to study the association between local side effects and potential factors associated with their occurrence. Results: About 250 asthmatic children aged ≤12 years (64 children <6 years, 186 children ≥6 years) taking inhaled budesonide via pressurised Metered Dose Inhaler (pMDI) were evaluated. Almost half (48.8%) of the enrolled children experienced at least one local side effect, either daily or frequently, in the preceding month. Though majority experienced a single side effect, 21% experienced two or more side effects. Thirsty feeling after inhalation was the most common reported side effect experienced by 31.2% children followed by cough during inhalation, sore throat and dysphonia which were experienced by 25.2%, 17% and 8% children, respectively. Perioral dermatitis was found in only one patient while none of the patients had tongue hypertrophy or oral thrush. On univariate logistic regression, thirsty feeling after inhalation was associated with older age (≥6 years) and higher dose of Budesonide (>400 μg/day). Cough during inhalation was found to be associated with older age, higher dose of Budesonide, poor compliance to treatment and incorrect technique of taking pMDI and sore throat was associated with poor compliance and incorrect technique. However, on multivariate logistic regression, only cough during inhalation was found to be associated with higher dose of Budesonide and poor compliance to treatment. Conclusion: Local side effects are common in asthmatic children using ICSs and should be routinely assessed during follow-up as a part of comprehensive asthma management plan.


2019 ◽  
pp. 01-11
Author(s):  
Catherine Sarfo-Walters ◽  
Susana Nsiah ◽  
Bright Oppong Afranie ◽  
Regina Owusu Banahene ◽  
Sampson Donkor

Background: Malaria is one of the leading causes of mortality among children below 5 years of age in Ghana. This study aimed to determine the barriers affecting the management of malaria in children under 5 years in Manhyia hospital, Ghana. Methods: This cross-sectional study was carried out in Manhyia hospital, Kumasi. Questionnaires were administered to 131 health workers as well as 132 guardians of the children below 5 years affected with malaria to obtain data including socio-demographic characteristics of the children, guardians and health workers, the knowledge and practices towards good management of malaria and the challenges faced by guardians and health workers in malaria management. Results: Majority of the infected children (38.6%) were between 1-6 months old. Route of drug administration (p=0.018) and those who were resistant to the action of the anti-malarial drugs (p<0.001) were significantly related to the outcome condition of the child after treatment. General body weakness (80.9%) was the common side effect of the anti-malaria drugs. There was no significant barrier affecting malaria management from the results from the guardians. However, affordability of the anti-malarial drug (24.2%) was a challenge to the parents/guardians. Conclusion: constant supply of quality but affordable drugs and adequate supervision working synergistically will ensure appropriate management of malaria in children and in turn improve the quality of healthcare.


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