scholarly journals PECULIARITIES OF THE CLINICAL COURSE AND TREATMENT OF SUBMUCOUS LEIOMYOMA OF THE UTERUS IN REPRODUCTIVE AGE WOMEN

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
M. A. Flaksemberh
2017 ◽  
pp. 107-110
Author(s):  
А. Kornatska ◽  
◽  
G. Chubei ◽  
M. Flaksemberg ◽  
◽  
...  

The objective: was to evaluate the possibility of using mifepristone (Gynestril) as a hormonal preparation for conservative myomectomy. Patients and methods. The effect of a three-month course of mifepristone (Gynestril) at a dose of 50 mg per day on the dynamics of clinical indicators, ultrasound, the results of surgical treatment in 30 women of reproductive age with uterine leiomyoma was studied. Results. The use of an antigestagenic drug for preoperative preparation led to a decrease in the incidence of pain syndrome, dysfunction of the pelvic organs in most patients. The presence of amenorrhea in 90% of women contributed to the normalization of hemoglobin. The positive dynamics of the mioma nodes sizes and the uterus made it possible to reduce the time of operative intervention and the volume of intraoperative blood loss. Conclusion. The use of antigestagen preparations, in particular mifepristone (Gynestril), for the purpose of preoperative preparation, allows obtaining the most positive result of organ-preserving treatment of uterine myoma in reproductive age women. Key words: leiomyoma of the uterus, reproductive age, preoperative preparation, mifepristone, Gynestril.


2019 ◽  
Vol 23 (1) ◽  
pp. 120-124
Author(s):  
M.B. Zaporozhchenko ◽  
A.V. Sidorenko ◽  
D.Yu. Parubina

The combined pathology of the uterus, leiomyoma and adenomyosis, is one of the pressing problems of modern medicine, and is accompanied by a deficiency of vitamins, and the main macro-, trace elements. The purpose — to study the content of folic acid, vitamins B1, D, E, ferritin in blood, zinc, copper, calcium in the blood and remote tissues of the uterus. 150 women were examined: 30 practically healthy women, and 120 patients with combined uterine pathology with leiomyoma and adenomyosis. Group I — practically healthy women; Group ІІА — patients with asymptomatic leiomyoma of the uterus and adenomyosis nodular, diffuse, diffuse-focal І, ІІ, ІІІ, ІV degrees of severity of active clinical course; group IB — patients with symptomatic leiomyoma of the uterus and adenomyosis diffuse, diffuse-focal І, II degrees of severity of inactive clinical course. The content of folic acid, vitamins B1, D, E, ferritin in blood, zinc, copper, calcium in blood and remote tissues of the uterus was studied, the hormonal status of women with combined uterus pathology. Determined that the level of folic acid was significantly lower in relation to the control group by 1.5 times, vitamin B1 — by 3.6 times, vitamin D — by 2,3 times, vitamin E — by 1.5 times. In groups ІІА, II B, the concentration of ferritin in comparison with group І was by 11.9 and by 13.4 times lower, respectively. In relation to the control group І, the content of Zn was lower in the group ІІА by 1.9; Cu — by 1.25 times more, in group IIB — by Zn 2.0 times less, Cu — by 1.2 times more, respectively. In group ІІА, the calcium content did not significantly differ from the indicators of the control group, in group IIB there was a significant increase in calcium levels by 1.2 times. The content of estradiol in patients of group IIB was by 1.5 times higher than in women of group ІІА, progesterone — by 1.15 times lower, luteinizing hormone — by 1.3 times less, follicle-stimulating hormone — by 1.2 times lower respectively. Thus, Determining the content of zinc, copper, calcium in the blood and remote tissues at case of a combined pathology of the uterus with leiomyoma and adenomyosis is of practical importance from the point of view of timely prevention of diseases.


2011 ◽  
Vol 7 (2) ◽  
pp. 96-102 ◽  
Author(s):  
Hiroko Watanabe ◽  
Takashi Sugiyama ◽  
Hiromitsu Chihara ◽  
Hideoki Fukuoka

2016 ◽  
Vol 106 (12) ◽  
pp. 2103-2110 ◽  
Author(s):  
Yuan He ◽  
An Pan ◽  
Ying Yang ◽  
Yuanyuan Wang ◽  
Jihong Xu ◽  
...  

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Dessie Abebaw Angaw ◽  
Alemakef Wagnew Melesse ◽  
Bisrat Misganaw Geremew ◽  
Getayeneh Antehunegn Tesema

Abstract Background Intimate partner violence is a serious global public health problem particularly in low-and middle-income countries such as Ethiopia where women's empowerment is limited. Despite the high prevalence of intimate partner violence in Ethiopia, there is limited evidence on the spatial distribution and determinants of intimate partner violence among reproductive-age women. Exploring the spatial distribution of intimate partner violence is crucial to identify hotspot areas of intimate partner violence to design targeted health care interventions. Therefore, this study aimed to investigate the spatial distribution and determinants of intimate partner violence among reproductive-age women in Ethiopia. Methods A secondary data analysis was done based on the 2016 Ethiopian Demographic and Health Survey (EDHS) data. A total weighted sample of 6090 reproductive-age women were included in the study. The spatial scan statistical analysis was done to identify the significant hotspot areas of intimate partner violence. A multilevel binary logistic regression analysis was fitted to identify significant determinants of intimate partner violence. Deviance, Intra-cluster Correlation Coefficient (ICC), Median Odds Ratio, and Proportional Change in Variance (PCV) were used for model comparison as well as for checking model fitness. Variables with a p-value less than 0.2 were considered in the multivariable analysis. In the multivariable multilevel analysis, the Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) were reported to declare statistical significance and strength of association between intimate partner violence and independent variables. Results The spatial analysis revealed that the spatial distribution of intimate partner violence was significantly varied across the country (Moran’s I = 0.1007, p-value < 0.0001). The SaTScan analysis identified a total of 192 significant clusters, of these 181 were primary clusters located in the Benishangul-Gumuz, Gambella, northwest Amhara, and west Oromia regions. In the multivariable multilevel analysis; women aged 45–49 years (AOR = 2.79, 95% CI 1.52–5.10), women attained secondary education (AOR = 0.61, 95% CI 0.38–0.98), women in the richest household (AOR = 0.58, 95% CI 0.35–0.97), > 10 family size (AOR = 3.85, 95% CI 1.41–10.54), and high community women empowerment (AOR = 0.66, 95% CI 0.49–0.8)) were significantly associated with intimate partner violence. Conclusions Intimate partner violence among reproductive-age women had significant spatial variation across the country. Women's age, education status, family size, community women empowerment, and wealth status were found significant determinants of intimate partner violence. Therefore, public health programs should design targeted interventions in identified hot spot areas to reduce the incidence of intimate partner violence. Besides, health programmers should scale up public health programs designed to enhance women's autonomy to reduce the incidence of intimate partner violence and its consequences.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Delayehu Bekele ◽  
Feiruz Surur ◽  
Balkachew Nigatu ◽  
Alula Teklu ◽  
Tewodros Getinet ◽  
...  

Abstract Background Ethiopia is the second most populous country in Africa, known for its high fertility and low contraceptive use. The magnitude of contraceptive use in the emerging regions of the country is below the national average. However, there is a paucity of evidence regarding the reasons for low contraceptive use in these regions. Therefore, this study aimed to assess contraceptive use and associated factors in the emerging regions of Ethiopia. Methods For the quantitative part, a community based cross-sectional study was conducted among 2891 reproductive age women who were selected by multistage sampling technique. Data were collected face to face using an open data kit software, and STATA version 14 was used for data analysis. Frequencies, percentages, summary measures and tables were used to summarize and present the data. Bivariable and multivariable logistic regression analyses were performed to identify factors associated with contraceptive use, by computing odds ratio with 95% confidence interval. Level of significance was considered at p-value < 0.05. For the qualitative part, phenomenological study was conducted among 252 health care workers and community members who were selected purposely. The data were collected by focused group discussions, in-depth interviews and key informant interviews. The data were audio-recorded in the local languages, and then translated to English verbatim. NVivo version 11 was used to analyze the data through a thematic analysis method. Results The overall contraceptive prevalence rate was 22.2%; with 11.7, 38.6, 25.5 and 8.8% for Afar, Benshangul Gumuz, Gambela and Somali Regions, respectively. Age, religion, education, marital status, family size, ideal children, knowledge and attitude were significantly associated with contraceptive use. Additionally, the qualitative study identified three themes as barriers to contraceptive use: individual, health care system and sociocultural factors. Conclusions Contraceptive prevalence rate was low in this study compared to the national average. Age, religion, education, marital status, family size, ideal children, knowledge and attitude were significantly associated with contraceptive use. From the qualitative aspect, individual, health care system and sociocultural factors were identified as barriers to contraceptive use. Therefore, the emerging regions of Ethiopia need special focus in increasing contraceptive use through behavioral influence/change.


2020 ◽  
pp. 101053952098314
Author(s):  
Shahina Begum ◽  
Himanshu Chaurasia ◽  
Kusum V. Moray ◽  
Beena Joshi

Data from National Family Health Survey (2015-2016) was analyzed to examine the contraceptive acceptance, discontinuation rates, and associated factors among reproductive age women in India over one year. Findings revealed that 11.7% accepted modern methods of which 68% were for spacing. Only 5% switched to other methods. Discontinuation rate was high among condom (56.8%) and oral contraceptive pill users (34.5%), among women aged less than 25 years, with parity less than 2, belonging to rural area, and having no education. Health concerns/side effects, husband’s disapproval, or method failure were most common reasons cited for discontinuation. The data show high discontinuation rates among some subgroups of women and for certain methods. Hence, women need to be provided options to switch methods to meet changing contraceptive needs and health priorities. Continuum of care with follow-up and counselling can facilitate sustained contraceptive use to avert unintended pregnancies.


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