Geographic distribution of Pythium insidiosum infections in the United States

2021 ◽  
pp. 1-5
Author(s):  
Don Nguyen ◽  
Raquel Vilela ◽  
Bruno M. Miraglia ◽  
Gabriella Vilela ◽  
Noora Jasem-Alali ◽  
...  
Keyword(s):  
Geographic Distribution ◽  
The United States ◽  
Skin Lesions ◽  
Microbial Culture ◽  
Serum Samples ◽  
Pythium Insidiosum ◽  
Southeastern Us ◽  
The Us ◽  
Histologic Evaluation ◽  
Diagnostic Modalities

Abstract OBJECTIVE To describe the geographic distribution of infections caused by Pythium insidiosum in dogs, horses, and other animal species in the US. ANIMALS For the last 20 years, we have collected data from cases of pythiosis in 1,150 horses, 467 dogs, and other species (59) from various geographic locations in the US. PROCEDURES Due to lost data (from 2006 to 2016), the selected cases include years 2000 to 2005 and 2016 to 2020. The selection of cases was based on infected host clinical features, serum samples demonstrating strong positive anti–P insidiosum IgG titers in serologic assays, and positive results on ≥ 1 of the following diagnostic modalities: microbial culture on 2% Sabouraud dextrose agar, histologic evaluation, PCR assay, and wet mount cytologic evaluation (with potassium hydroxide). RESULTS Most confirmed P insidiosum infections were found in horses and dogs in the southeastern US. Interestingly, in Texas, no cases were found west of longitude 100°W. Few pythiosis cases were diagnosed in west-coast states. Equine cases were more often diagnosed during summer and fall months, but canine cases were more often diagnosed between September and February. Cases in other species were discovered in the same geographic areas as those in dogs and horses. CLINICAL RELEVANCE To our knowledge, this is the first report providing the ecological distribution of P insidiosum infection in affected species in the US. Results of this study illustrated the importance of including P insidiosum in the differential diagnostic scheme of nonhealing skin lesions or intestinal granulomatous masses, particularly in dogs and horses inhabiting or having visited endemic areas.

scholarly journals Temporal and spatial variations in freeze warnings in the conterminous United States: 2005–2018

2019 ◽  
Vol 139 (3-4) ◽  
pp. 1379-1384
Author(s):  
Brandon Lawhorn ◽  
Robert C. Balling
Keyword(s):  
United States ◽  
Temporal Trends ◽  
The United States ◽  
Temporal Variations ◽  
Atmospheric Composition ◽  
Southeastern Us ◽  
The Us ◽  
Temporal And Spatial ◽  
Frost Free Period ◽  
Spatial And Temporal Trends

AbstractIt is well-documented that the United States (US), along with other mid-latitude land locations, has experienced warming in recent decades in response to changes in atmospheric composition. Among other changes, Easterling (2002) reported that the frost-free period is now longer across much of the US with the first frost in fall occurring later and the last freeze in spring occurring earlier. In this investigation, we explore spatial and temporal variations in all freeze warnings issued by the US National Weather Service. Freeze warning counts are highest in the southeastern US peaking overall in the spring and fall months. Freeze warnings tend to occur more toward summer moving northward and westward into more northerly states. Consistent with the warming in recent decades, we find statistically significant northward movements in freeze warning centroids in some months (December, February) across the study period (2005–2018). Detection of spatial and temporal trends in freeze warnings may be of interest to any number of scientists with applied climatological interests.

scholarly journals Continental outflow from the US to the upper troposphere over the North Atlantic during the NASA INTEX-NA Airborne Campaign

2008 ◽  
Vol 8 (7) ◽  
pp. 1989-2005 ◽  
Author(s):  
S. Y. Kim ◽  
R. Talbot ◽  
H. Mao ◽  
D. Blake ◽  
S. Vay ◽  
...  
Keyword(s):  
Boundary Layer ◽  
North Atlantic ◽  
The United States ◽  
Upper Troposphere ◽  
Mixing Ratios ◽  
The North ◽  
Southeastern Us ◽  
The Us ◽  
The North Atlantic ◽  
Continental Outflow

Abstract. A case of continental outflow from the United States (US) was examined using airborne measurements from NASA DC-8 flight 13 during the Intercontinental Chemical Transport Experiment – North America (INTEX-NA). Mixing ratios of methane (CH4) and carbon monoxide (CO) at 8–11 km altitude over the North Atlantic were elevated to 1843 ppbv and 134 ppbv respectively, while those of carbon dioxide (CO2) and carbonyl sulfide (COS) were reduced to 372.4 ppmv and 411 pptv respectively. In this region, urban and industrial influences were evidenced by elevated mixing ratios and good linear relationships between urban and industrial tracers compared to North Atlantic background air. Moreover, low mixing ratios and a good correlation between COS and CO2 showed a fingerprint of terrestrial uptake and minimal dilution during rapid transport over a 1–2 day time period. Analysis of synoptic conditions, backward trajectories, and photochemical aging estimates based on C3H8/C2H6 strongly suggested that elevated anthropogenic tracers in the upper troposphere of the flight region were the result of transport via convection and warm conveyor belt (WCB) uplifting of boundary layer air over the southeastern US. This mechanism is supported by the similar slope values of linear correlations between long-lived (months) anthropogenic tracers (e.g., C2Cl4 and CHCl3) from the flight region and the planetary boundary layer in the southeastern US. In addition, the aircraft measurements suggest that outflow from the US augmented the entire tropospheric column at mid-latitudes over the North Atlantic. Overall, the flight 13 data demonstrate a pervasive impact of US anthropogenic emissions on the troposphere over the North Atlantic.

scholarly journals Geographic Distribution of Foot and Ankle Orthopaedic Surgeons Throughout the United States

2020 ◽  
Vol 5 (4) ◽  
pp. 2473011420S0008
Author(s):  
Hui Zhang ◽  
Matthew G. Fanelli ◽  
Coleman Cush ◽  
Benjamin Wagner ◽  
Louis C. Grandizio ◽  
...  
Keyword(s):  
Geographic Distribution ◽  
Pearson Correlation ◽  
Negative Relationship ◽  
The United States ◽  
Economic Factors ◽  
Foot And Ankle ◽  
Congressional District ◽  
Poverty Level ◽  
Congressional Districts ◽  
The Us

Category: Other Introduction/Purpose: Orthopaedic Surgery has become increasingly subspecialized since fellowships were established in the 1970s. Previous investigations within hand and urologic surgery have demonstrated an uneven geographic distribution within these subspecialties. Economic factors can influence surgeon distribution within a particular geographic region. At present, the geographic distribution of orthopaedic foot and ankle (OFA) surgeons in the US is poorly defined. The purpose of this investigation is to determine the geographic distribution of OFA surgeons in the US. We hypothesize that there will be substantial differences in OFA surgeon density throughout the US and that economic factors may play a role in access to subspecialty OFA care. Methods: A current membership list was obtained from the American Orthopaedic Foot & Ankle Society (AOFAS). Active AOFAS members were categorized relative to states and US House of Representatives Congressional Districts. Using publicly available census data, we recorded the population within each state and district as well as the percentage of families and people with income below the federally defined poverty level. Descriptive statistics were utilized for demographic information. The relationship between income level and the number of surgeons was determined using a Pearson correlation. These data were used to generate OFA surgeons per capita at a state and congressional district level. This information was also used to generate choropleth maps comparing surgeon density and poverty. Results: We identified a list of 1,103 active AOFAS members with 1,311 practice addresses. There was an average of 21.2 OFA surgeons per state. There was an average of 0.38 and 0.40 OFA surgeons per 100,000 people in each state and congressional district respectively. The District of Columbia, VT, WY, and NE had the highest OFA surgeon density. WV, KY, NM, RI had the lowest density. 75 congressional districts had no OFA surgeons. There was a statistically significant negative relationship demonstrating that regions with higher levels of poverty had fewer OFA surgeons, with a Pearson correlation coefficient of -0.14, (P-value = 0.008). This relationship is further illustrated in Figure 1. Conclusion: There is wide geographic variation of OFA surgeon density throughout the US. Regions with higher levels of poverty have less access to OFA surgeons compared to regions with lower poverty levels. Understanding these trends may aid in developing both recruitment and referal strategies for complex foot and ankle care in underserved regions.

scholarly journals SARS surveillance case definition updated in United States

2003 ◽  
Vol 7 (18) ◽  
Author(s):  
Keyword(s):  
United States ◽  
Severe Acute Respiratory Syndrome ◽  
Laboratory Tests ◽  
Laboratory Data ◽  
The United States ◽  
Case Definition ◽  
Sars Coronavirus ◽  
Serum Samples ◽  
The Us

The surveillance case definition for Severe Acute Respiratory Syndrome (SARS) has been updated for the United States to take account of the results of laboratory tests for SARS-coronavirus (SARS-CoV) that are becoming increasingly available (1) (http://www.cdc.gov/mmwr/preview/mmwrhtml/mm52d429a1.htm). Reported cases of SARS in the US will continue to be classified as suspect or probable; however, these cases can be further classified as laboratory-confirmed or -negative if laboratory data are available and complete, or as laboratory-indeterminate if specimens are not available or testing is incomplete. Obtaining convalescent serum samples to make a final determination about infection with SARS-CoV is critical.

Trends in the geographic distribution of cancer clinical trials in the US: 2008-2015.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 6515-6515
Author(s):  
Caroline Savage Bennette ◽  
Wei-Jhih Wang ◽  
Scott David Ramsey ◽  
Jean A. McDougall
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Geographic Distribution ◽  
Gini Coefficient ◽  
The United States ◽  
Cancer Clinical Trial ◽  
Cancer Clinical Trials ◽  
Hospital Service ◽  
The Gini Coefficient ◽  
The Us

6515 Background: Access to and patient enrollment in cancer clinical trials is likely strongly impacted by where trial enrollment sites are located. Our objective was to evaluate temporal trends in the geographic location of cancer clinical trials launched in the US. Methods: We obtained the recruiting location(s) of all public- and privately-funded phase II/ III cancer clinical trials launched in the US between 2008 and 2015 from the ClinicalTrials.gov database. We linked the recruiting location(s) of each trial to the relevant hospital service area (HSA), which are defined by ZIP codes as local health care markets for hospital care (n = 3436). We estimated the number of cancer clinical trial sites in each HSA each year between 2008 and 2015. We also calculated a statistical measure of inequality, the Gini coefficient. The Gini coefficient would be 0 if all hospital service areas launched the same number of cancer clinical trials, and would be 1 if all cancer clinical trials were launched in only a single hospital service area. Results: 62% of HSAs (n = 2133) did not launch a single cancer clinical trial between 2008 and 2015. There was a small and non-statistically significant decline in the overall number of cancer clinical trial sites in the United States between 2008 and 2015 (-1.6% per year [95% CI: -4.0, 0.9]). During this same period of time, however, inequality in the geographic distribution of cancer clinical trial sites considerably deepened. For example, in 2008-09, no trials were launched in 68% of HSAs while 19% of trial sites were in only 1% of HSAs. Trials launched in 2014-15 were even more concentrated: no new trials were launched in 74% of HSAs while 25% of trial sites were in the top 1% of HSAs. The Gini coefficient increased significantly from 0.683 (95% CI: 0.666, 0.700) for trials launched in 2008-09 to 0.726 (95% CI: 0.706, 0.746) for those launched in 2014-15. Conclusions: Our findings indicate increased inequality in the geographic distribution of cancer clinical trials launched in the United States since 2008. The underlying causes and consequences of such increasing concentration warrant further analysis given the importance in ensuring equitable geographic access to cancer clinical trials in the US.

Relation of Statistically Significant, Abnormal, and Typical WAIS-R VIQ-PIQ Discrepancies to Full Scale IQs

2000 ◽  
Vol 16 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Louis M. Hsu ◽  
Judy Hayman ◽  
Judith Koch ◽  
Debbie Mandell
Keyword(s):  
Graphical Method ◽  
The United States ◽  
Full Scale ◽  
True Score ◽  
Absolute Value ◽  
Normative Population ◽  
The Us ◽  
The Mean ◽  
And Performance ◽  
Quadratic Models

Summary: In the United States' normative population for the WAIS-R, differences (Ds) between persons' verbal and performance IQs (VIQs and PIQs) tend to increase with an increase in full scale IQs (FSIQs). This suggests that norm-referenced interpretations of Ds should take FSIQs into account. Two new graphs are presented to facilitate this type of interpretation. One of these graphs estimates the mean of absolute values of D (called typical D) at each FSIQ level of the US normative population. The other graph estimates the absolute value of D that is exceeded only 5% of the time (called abnormal D) at each FSIQ level of this population. A graph for the identification of conventional “statistically significant Ds” (also called “reliable Ds”) is also presented. A reliable D is defined in the context of classical true score theory as an absolute D that is unlikely (p < .05) to be exceeded by a person whose true VIQ and PIQ are equal. As conventionally defined reliable Ds do not depend on the FSIQ. The graphs of typical and abnormal Ds are based on quadratic models of the relation of sizes of Ds to FSIQs. These models are generalizations of models described in Hsu (1996) . The new graphical method of identifying Abnormal Ds is compared to the conventional Payne-Jones method of identifying these Ds. Implications of the three juxtaposed graphs for the interpretation of VIQ-PIQ differences are discussed.

The Politics of Prophecy: The US Culture Wars and the Battle Over Public Education in the Left Behind Series for Kids

2009 ◽  
Vol 2 (1) ◽  
pp. 1-27
Author(s):  
Ann Abate Michelle
Keyword(s):  
Public Education ◽  
The United States ◽  
Culture Wars ◽  
Church History ◽  
Good News ◽  
Cultural Issues ◽  
School Prayer ◽  
Left Behind ◽  
Religious Books ◽  
The Us

This essay argues that in spite of their obvious Biblically-based subject matter, clear Christian content, and undeniable evangelical perspective, the Left Behind novels for kids are not simply religious books; they are also political ones. Co-authors Tim LaHaye and Jerry B. Jenkins may claim that their narratives are interested in sharing the good news about Jesus for the sake of the future, but they are equally concerned with offering commentary on contentious US cultural issues in the present. Given the books’ adolescent readership, they are especially preoccupied with the ongoing conservative crusade concerning school prayer. As advocates for this issue, LaHaye and Jenkins make use of a potent blend of current socio-political arguments and of past events in evangelical church history: namely, the American Sunday School Movement (ASSM). These free, open-access Sabbath schools became the model for the public education system in the United States. In drawing on this history, the Left Behind series suggests that the ASSM provides an important precedent for the presence not simply of Christianity in the nation's public school system, but of evangelical faith in particular.

The United States and the Iranian Nuclear Programme

2018 ◽  
Author(s):  
Steven Hurst
Keyword(s):  
United States ◽  
Decision Making ◽  
Domestic Politics ◽  
The United States ◽  
Nixon Administration ◽  
Comprehensive Plan ◽  
The Us ◽  
Nuclear Issue ◽  
The Relationship

The United States, Iran and the Bomb provides the first comprehensive analysis of the US-Iranian nuclear relationship from its origins through to the signing of the Joint Comprehensive Plan of Action (JCPOA) in 2015. Starting with the Nixon administration in the 1970s, it analyses the policies of successive US administrations toward the Iranian nuclear programme. Emphasizing the centrality of domestic politics to decision-making on both sides, it offers both an explanation of the evolution of the relationship and a critique of successive US administrations' efforts to halt the Iranian nuclear programme, with neither coercive measures nor inducements effectively applied. The book further argues that factional politics inside Iran played a crucial role in Iranian nuclear decision-making and that American policy tended to reinforce the position of Iranian hardliners and undermine that of those who were prepared to compromise on the nuclear issue. In the final chapter it demonstrates how President Obama's alterations to American strategy, accompanied by shifts in Iranian domestic politics, finally brought about the signing of the JCPOA in 2015.

‘To see oursels as ithers see us’: Reflections on Scottish Independence from the United States

2014 ◽  
Vol 23 (3) ◽  
pp. 381-388 ◽  
Author(s):  
Euan Hague ◽  
Alan Mackie
Keyword(s):  
United States ◽  
The United States ◽  
The Us ◽  
Scottish Independence ◽  
The Uk ◽  
Scottish Diaspora

The United States media have given rather little attention to the question of the Scottish referendum despite important economic, political and military links between the US and the UK/Scotland. For some in the US a ‘no’ vote would be greeted with relief given these ties: for others, a ‘yes’ vote would be acclaimed as an underdog escaping England's imperium, a narrative clearly echoing America's own founding story. This article explores commentary in the US press and media as well as reporting evidence from on-going interviews with the Scottish diaspora in the US. It concludes that there is as complex a picture of the 2014 referendum in the United States as there is in Scotland.

Palestine Unbound

2018 ◽  
Vol 47 (3) ◽  
pp. 130-134
Keyword(s):  
United States ◽  
Human Rights ◽  
Task Force ◽  
The United States ◽  
Donald Trump ◽  
Tel Aviv ◽  
The Us ◽  
Intention To Move ◽  
Arab Israeli Conflict ◽  
The U.S

This section, updated regularly on the blog Palestine Square, covers popular conversations related to the Palestinians and the Arab-Israeli conflict during the quarter 16 November 2017 to 15 February 2018: #JerusalemIstheCapitalofPalestine went viral after U.S. president Donald Trump recognized Jerusalem as the capital of Israel and announced his intention to move the U.S. embassy there from Tel Aviv. The arrest of Palestinian teenager Ahed Tamimi for slapping an Israeli soldier also prompted a viral campaign under the hashtag #FreeAhed. A smaller campaign protested the exclusion of Palestinian human rights from the agenda of the annual Creating Change conference organized by the US-based National LGBTQ Task Force in Washington. And, UNRWA publicized its emergency funding appeal, following the decision of the United States to slash funding to the organization, with the hashtag #DignityIsPriceless.

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