scholarly journals Case Report of a Term Newborn with Prenatally Diagnosed Alobar Holoprosencephaly

2020 ◽  
Vol 20 (3) ◽  
pp. 138-142
Author(s):  
E Malchova ◽  
K. Demova
Keyword(s):  
Cerebral Hemispheres ◽  
Structural Abnormality ◽  
Brain Hemispheres ◽  
Live Births ◽  
Term Newborn ◽  
Degree Of Separation ◽  
Health Complications ◽  
The Brain ◽  
Incomplete Cleavage

AbstractHoloprosencephaly is a congenital structural abnormality of brain resulting from incomplete cleavage of prosencephalon into two cerebral hemispheres. It is classified as a disorder of organogenesis and brain histogenesis and is typically associated with facial anomalies.Holoprosencephaly is relatively rare – the incidence in live births varies between 1:10,000 – 1:15,000 but is described in 1 out of 250 spontaneously aborted embryos.There are four major varieties of holoprosencephaly according to the degree of separation of the brain hemispheres; this division is crucial for the patient’s prognosis. Three classic subtypes are alobar, semilobar, and lobar holoprosencephaly and there is also a fourth subtype called middle interhemispheric variant.We present a case study of a term newborn with prenatally diagnosed holoprosencephaly with severe facial dys-morphism and associated health complications.

scholarly journals Assessment Of Afasia in Stroke Patients: Case Study

2020 ◽  
Vol 3 (2) ◽  
pp. 210-219
Author(s):  
Dwi Febryanto ◽  
Retnaningsih ◽  
Fitria Handayani
Keyword(s):  
Language Comprehension ◽  
Early Assessment ◽  
Stroke Patients ◽  
Reading And Writing ◽  
Brain Hemispheres ◽  
Speech Styles ◽  
Care Costs ◽  
The Brain

Introduction: Aphasia is understood as difficulty in understanding or producing language caused by disorders involving the brain hemispheres. Early assessment of aphasia is very important to prevent the emergence of telegraphic speech styles, improve welfare, independence, social participation, quality of life, reduce length of stay and care costs, but there is little literature on this subject, especially in stroke patients. Purpose: This study is to provide an overview of the assessment of aphasia in stroke patients. Methods: The design of a case study involving 6 participants and data collection was carried out by conducting an assessment using the Language Aphasia Screening Test (LAST) instrument which was monitored for 3 days, including monitoring errors for naming images, monitoring mismatches repeating words and sentences, monitoring spontaneous pronunciation, monitoring image comprehension, monitoring comprehension of verbal instructions.Results: A total of 6 ischemic stroke patients were found wrong in repeating words and sentences. Conclusion: In aphasic stroke patients all language modalities are impaired, ranging from spontaneous speech, repetition, naming, language comprehension, reading and writing

Brain Tumor Detection via Asymmetry Quantification across Mid Sagittal Plane

2020 ◽  
Vol 13 ◽  
Author(s):  
Shoaib Amin Banday ◽  
Mohammad Khalid Pandit
Keyword(s):  
Brain Tumor ◽  
Brain Tumors ◽  
Sagittal Plane ◽  
Early Stage ◽  
Imaging Techniques ◽  
Complex Structure ◽  
Magnetic Resonance Images ◽  
Absolute Difference ◽  
Brain Hemispheres ◽  
The Brain

Introduction: Brain tumor is among the major causes of morbidity and mortality rates worldwide. According to National Brain Tumor Foundation (NBTS), the death rate has nearly increased by as much as 300% over last couple of decades. Tumors can be categorized as benign (non-cancerous) and malignant (cancerous). The type of the brain tumor significantly depends on various factors like the site of its occurrence, its shape, the age of the subject etc. On the other hand, Computer Aided Detection (CAD) has been improving significantly in recent times. The concept, design and implementation of these systems ascend from fairly simple ones to computationally intense ones. For efficient and effective diagnosis and treatment plans in brain tumor studies, it is imperative that an abnormality is detected at an early stage as it provides a little more time for medical professionals to respond. The early detection of diseases has predominantly been possible because of medical imaging techniques developed from past many decades like CT, MRI, PET, SPECT, FMRI etc. The detection of brain tumors however, has always been a challenging task because of the complex structure of the brain, diverse tumor sizes and locations in the brain. Method: This paper proposes an algorithm that can detect the brain tumors in the presence of the Radio-Frequency (RF) inhomoginiety. The algorithm utilizes the Mid Sagittal Plane as a landmark point across which the asymmetry between the two brain hemispheres is estimated using various intensity and texture based parameters. Result: The results show the efficacy of the proposed method for the detection of the brain tumors with an acceptable detection rate. Conclusion: In this paper, we have calculated three textural features from the two hemispheres of the brain viz: Contrast (CON), Entropy (ENT) and Homogeneity (HOM) and three parameters viz: Root Mean Square Error (RMSE), Correlation Co-efficient (CC), and Integral of Absolute Difference (IAD) from the intensity distribution profiles of the two brain hemispheres to predict any presence of the pathology. First a Mid Sagittal Plane (MSP) is obtained on the Magnetic Resonance Images that virtually divides brain into two bilaterally symmetric hemispheres. The block wise texture asymmetry is estimated for these hemispheres using the above 6 parameters.

scholarly journals Basal Ganglia Herniation into the Fourth Ventricle

1997 ◽  
Vol 24 (1) ◽  
pp. 62-63 ◽  
Author(s):  
Mensura Altumbabic ◽  
Marc R. Del Bigio ◽  
Scott Sutherland
Keyword(s):  
Basal Ganglia ◽  
Intracerebral Hemorrhage ◽  
Fourth Ventricle ◽  
Transtentorial Herniation ◽  
Intracerebral Bleeding ◽  
Rare Phenomenon ◽  
The Brain

ABSTRACT:Background:Transtentorial herniation of large cerebral fragments is a rare phenomenon.Method:Case StudyResults:Examination of the brain of a 35-year-old male showed massive intracerebral hemorrhage resulting in displacement of basal ganglia components into the fourth ventricle.Conclusions:Sufficiently rapid intracerebral bleeding can dissect fragments of cerebrum and displace them long distances across the tentorial opening.

A Case of Rare Monstrosity in a Calf

1966 ◽  
Vol 3 (3) ◽  
pp. 226-233 ◽  
Author(s):  
L. Dozsa
Keyword(s):  
Congenital Anomalies ◽  
The Other ◽  
Cerebral Hemispheres ◽  
The Brain ◽  
Heifer Calf

The literature on congenital anomalies of calves is reviewed, and the author describes a case of malformation in a purebred Hereford heifer calf. This animal, which lived for 3 days, had two muzzles and two sets of rudimentary teeth and lower lips. There were four cerebral hemispheres but no duplication of the other parts of the brain. On the basis of the organs which were duplicated, the monster was termed a disprosopus, distomus, diotus, triophthalmos, ditelencephalus and monometencephalus.

Evaluation of the activity of antihypoxants with an isothiourea structure in a model of hypercapnic hypoxia with a shutdown of the cerebral hemispheres

2021 ◽  
Vol 19 (1) ◽  
pp. 55-63
Author(s):  
Vera V. Marysheva ◽  
Vladimir V. Mikheev ◽  
Petr D. Shabanov
Keyword(s):  
Acute Hypoxia ◽  
Life Time ◽  
The Body ◽  
Cerebral Hemispheres ◽  
Antihypoxic Activity ◽  
Hypoxic Episode ◽  
Hypoxia With Hypercapnia ◽  
Hypercapnic Hypoxia ◽  
Outbred Mice ◽  
The Brain

PURPOSE: To study the effect of amtizol, 2-aminobenzthiazole (2-ABT) and 2-amino-4-acetylthiazolo[5,4-b]indole (BM-606) on the resistance of male outbred mice to acute hypoxia with hypercapnia under conditions of isolated functioning of one from the hemispheres, as well as both hemispheres of the brain. METHODS: A model of acute hypoxia with hypercapnia (canned hypoxia) was used in mice of the same mass, the lifespan of all animals was determined. Temporary shutdown of the cortex of one of the hemispheres or both hemispheres was achieved by epidural application of filter paper moistened with 25% potassium chloride solution, creating a spreading depression according to Leao. Amtizol, 2-aminobenzthiazole (2-ABT) and 2-amino-4-acetylthiazolo[5,4-b]indole (BM-606) at equimolar doses of 25, 32.5, and 50 mg/kg, respectively were used as pharmacological analyzers, the compounds were injected intraperitoneally 30 min before the hypoxic episode. RESULTS: It was shown that, in contrast to amtizol, 2-ABT and VM-606 increase the life time of experimental animals when any hemisphere is turned off. The use of drugs when both hemispheres were turned off revealed that amtizol has approximately equal effect on the brain and the rest of the body, in 2-ABT antihypoxic activity is 1/3 associated with the brain, in VM-606 exclusively with the brain. CONCLUSION: The experimental model used in this work makes it possible to quite easily evaluate the effect of either one drug or compare several drugs, their role in the functioning of the cerebral hemispheres, on which part of the sample highly resistant or low resistant to hypoxia they have the greatest effect.

Changes in the types of dominance of the brain hemispheres of Russian schoolchildren from 2005 to 2020

2021 ◽  
Author(s):  
Marina Petrovna Markova ◽  
Elizaveta Vladimirovna Ballakh
Keyword(s):  
Brain Hemispheres ◽  
The Brain

Practice Parameter: Management of Hyperbilirubinemia in the Healthy Term Newborn

PEDIATRICS ◽  
1994 ◽  
Vol 94 (4) ◽  
pp. 558-565
Author(s):  
◽  
Keyword(s):  
Serum Bilirubin ◽  
Elevated Serum ◽  
The United States ◽  
Total Serum ◽  
Brain Cells ◽  
Albumin Concentration ◽  
Specific Level ◽  
Term Newborn ◽  
Term Newborns ◽  
The Brain

Each year approximately 60% of the 4 million newborns in the United States become clinically jaundiced. Many receive various forms of evaluation and treatment. Few issues in neonatal medicine have generated such long-standing controversy as the possible adverse consequences of neonatal jaundice and when to begin treatment. Questions regarding potentially detrimental neurologic effects from elevated serum bilirubin levels prompt continuing concern and debate, particularly with regard to the management of the otherwise healthy term newborn without risk factors for hemolysis. Although most data are based on infants with birth weights ≥2500 g, "term" is hereafter defined as 37 completed weeks of gestation. Under certain circumstances, bilirubin may be toxic to the central nervous system and may cause neurologic impairment even in healthy term newborns. Most studies, however, have failed to substantiate significant associations between a specific level of total serum bilirubin (TSB) during nonhemolytic hyperbilirubinemia in term newborns and subsequent IQ or serious neurologic abnormality (including hearing impairment). Other studies have detected subtle differences in outcomes associated with TSB levels, particularly when used in conjunction with albumin binding tests and/or duration of exposure. In almost all published studies, the TSB concentration has been used as a predictor variable for outcome determinations. Factors influencing bilirubin toxicity to the brain cells of newborn infants are complex and incompletely understood; they include those that affect the serum albumin concentration and those that affect the binding of bilirubin to albumin, the penetration of bilirubin into the brain, and the vulnerability of brain cells to the toxic effects of bilirubin.

Four ways mind–body infused coaching approaches sharpen executives’ performance

2018 ◽  
Vol 17 (6) ◽  
pp. 282-289
Author(s):  
Alison Horstmeyer
Keyword(s):  
Emotional Intelligence ◽  
Work Performance ◽  
Holistic Approach ◽  
Personality Types ◽  
Content Type ◽  
Whole Person ◽  
Body Practices ◽  
The Brain ◽  
Practical Implications

Purpose This paper aims to describe mind–body infused coaching and to explain four distinct effects it can have on organizational executives and employees. Design/methodology/approach A review of theory and research on mind–body practices, emotional intelligence and work performance was conducted. A case study from the author’s experience also is included. Findings Mind–body infused coaching activates employees’ awareness, ignites a strengths-based approach, improves inner workings of the brain, boosts emotional intelligence and promotes curiosity. Practical implications HR professionals and managers are encouraged to obtain training in evidence-based mind–body principles to improve and sustain outcomes when coaching organizational executives and employees. Originality/value Conventional coaching approaches tend to be highly reductionistic by focusing solely on employees’ personality types, soft skills or achievement of specific goals. This paper discusses a holistic approach to coaching the whole person and outlines four specific benefits that could be anticipated as a result.

scholarly journals The localization of function in the brain

1874 ◽  
Vol 22 (148-155) ◽  
pp. 228-232 ◽  
Keyword(s):  
Experimental Investigation ◽  
Grey Matter ◽  
Corpus Striatum ◽  
Lunatic Asylum ◽  
Cerebral Hemispheres ◽  
The West ◽  
Exact Localization ◽  
Medical Reports ◽  
The Brain

The chief contents of this paper are the results of an experimental investigation tending to prove that there is a localization of function in special regions of the cerebral hemispheres. In a former paper published by the author in the ‘West Riding Lunatic Asylum Medical Reports,’ vol. iii. 1873, the results were given of experiments on rabbits, cats, and dogs, made specially for the purpose of testing the theory of Hughlings Jackson, that localized and unilateral epilepsies are caused by irritation or “discharging lesions” of the grey matter of the hemispheres in the region of the corpus striatum. Besides confirming Hughlings Jackson’s views, the author’s researches indicated an exact localization in the hemispheres of centres, or regions, for the carrying out of simple and complex muscular movements of a definite character, and described by him as of a purposive, or expressional, nature.

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