scholarly journals Relationship between hematological parameters and glycemic control in type 2 diabetes mellitus patients

2019 ◽  
Vol 38 (2) ◽  
pp. 164-171 ◽  
Author(s):  
Dragana Milosevic ◽  
Violeta Lukic Panin
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Care Center ◽  
Health Care Center ◽  
Study Results

Summary Background Diabetes mellitus (DM) with its micro- and macrocomplications is the leading global epidemic of the 21st century. The aim of the research is to determine possible changes in the complete blood count (CBC) parameters depending on glycemic controlin patients with Type 2 diabetes mellitus (T2DM). Methods The study included a total of 178 patients with T2DM, both gender over the age of 40 years, from the Health Care Center »Dr Milorad Mika Pavlović« Indjija, Serbia. To notice the possible correlation between the CBC parameters and glucose control in T2DM, the subjects were divided in two groups with HbA1c ≤ 7% and with HbA1c>7%. We analysed CBC parameters, parameters of glycoregulation, lipid status using standard biochemical methods, performed anthropometric measurements and collected patients data by questionnaire and electronic patient card. Results There was statistical difference between HbA1c groups for PMDW (p=0.045), HDL (p=0.0067). Using univariate linear regression it is shown that PCT was correlated with WBC (p=0.0005), neutrophils (p=0.046), monocytes (p=0.003); MPM was associated with MPV (p=0.0005); MPC (p=0.0005), PDW (P=0.0005), GLU0 (p=0.034), HDL-C (p=0.005); PMDW was correlated with HbA1c% (p=0.049), GLU0 (p=0.013), HDL-C (p=0.001), BW (p=0.043) in all patients. Conclusions Based on our study results it may be concluded that some of the parameters of CBC could be useful tool in following glycemic control of diabetics.

scholarly journals Factors Associated with Long-Term Control of Type 2 Diabetes Mellitus

2016 ◽  
Vol 2016 ◽  
pp. 1-8 ◽  
Author(s):  
Mohammed Badedi ◽  
Yahiya Solan ◽  
Hussain Darraj ◽  
Abdullah Sabai ◽  
Mohamed Mahfouz ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Care Center ◽  
Poor Glycemic Control ◽  
Health Care Center ◽  
Factors Associated

Aims.This study assessed factors associated with glycemic control among Saudi patients with Type 2 diabetes mellitus (T2DM).Methods.We conducted an analytical cross-sectional study, which included a random sample of 288 patients with T2DM proportional to the diabetes population of each primary health care center in Jazan city, Kingdom of Saudi Arabia.Results.More than two-thirds (74%) of patients had poor glycemic control. Lack of education, polypharmacy, and duration of diabetes ≥ 7 years were significantly associated with higher glycated hemoglobin (HbA1c). Moreover, patients who were smoker or divorced were significantly more likely to have higher HbA1c. The patients who did not comply with diet or take their medications as prescribed had poor glycemic control. The study found lower HbA1c levels among patients who received family support or had close relationship with their physicians. Similarly, knowledgeable patients towards diabetes or those with greater confidence in ability to manage self-care behaviors had a lower HbA1c. In contrast, risk factors such as depression or stress were significantly correlated with poorer glycemic control.Conclusion.The majority of T2DM patients had poor glycemic control. The study identified several factors associated with glycemic control. Effective and tailored interventions are needed to mitigate exposure to these risk factors. This would improve glycemic control and reduce the risks inherent to diabetes complications.

Fasting in Ramadan is safe for Individuals Suffering from Type 2 Diabetes Mellitus in Pakistan

2020 ◽  
Author(s):  
Fatima Jehangir
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Care Center ◽  
P Value ◽  
Risk Category ◽  
Drug Induced ◽  
Ramadan Fasting ◽  
Health Care Center

Background: Whether diabetics should fast or not in Ramadan has been a controversial idea since long and the answer even more debatable. It confers safety measures to be known by the diabetics thoroughly, such as when to break the fast and what the hypoglycemic cut offs are. We aimed to determine hypoglycemic events and safety of Ramadan fasting among individuals with Type 2 Diabetes Mellitus (DM). Methods: This was an observational study enrolling diabetics who decided to fast in Ramadan, were aged >18 years, visited the primary health care center in Sikanderabad and Clifton clinic and gave consent to participate in the study. The exclusion criteria was Type 1 Diabetes Mellitus, Gestational diabetes, drug induced Diabetes and Maturity Onset Diabetes of the Young. A total of 103 participants were included in the study. Data was captured pre-Ramadan, during Ramadan and post-Ramadan in the year 2019. Multivariate Logistic regression was computed and chi-square taken for association of risk factors with hypoglycemia. P-value <0.05 was considered significant. Results: Mean HbA1c before Ramadan was 9.2%+2.1 and after Ramadan 7.7%+1.4 (P-value<0.05) showing a reduction of 1.5%. Mean weight of the patients before Ramadan was 68.3kg+1.6 and during Ramadan 64.8kg+1.4(p-value <0.00) showing a dip of 3.5 kg however mean weight 1 month after Ramadan was 66.5kg+14.9 depicting a rise again of 1.8kgs. Higher the risk category of American Heart Association, those who had hypoglycemic events before Ramadan and those on basal-bolus combination insulin had more hypoglycemic events (p-value <0.05). Conclusion: Fasting in Ramadan shows a major reduction in weight (3.5kg) as well as corrects hyperglycemia (1.5%). However, hypoglycemia was attributed to high risk patients only hence Ramadan fasting proved to be quite safe in individuals with Type 2 DM.

scholarly journals Identification of Drug-Related Problems in Hypertension Comorbid Type 2 Diabetes Mellitus Patients at Primary Health Care Center Batununggal District Bandung

2021 ◽  
Vol 4 (3) ◽  
pp. 219-225
Author(s):  
Vina Septiani ◽  
Pudjiastuti Kartidjo ◽  
Alfi Nurul Islamiyah ◽  
Abdul Aziz MSW ◽  
Iis Rukmawati
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Health Care ◽  
Type 2 Diabetes Mellitus ◽  
Care Center ◽  
Drug Related Problems ◽  
Inclusion Criteria ◽  
Health Care Center ◽  
Primary Health

Many factors can increase the risk of hypertension, one of which is diabetes mellitus. The study aims to provide an overview of Drug-Related Problems (DRPs) in patients with hypertension comorbid type 2 diabetes mellitus at Primary Health Care Center Batununggal District Bandung. This research was an observational study with retrospective data collection and descriptive analysis. Data were taken from patient prescriptions January-December 2019 period. The sample inclusion criteria are patients aged 30-75 years, patients diagnosed with hypertension comorbid type 2 diabetes mellitus, and patients treated in January-December 2019. The number of samples that met the inclusion criteria was 268 patients, of which 69 patients (25.75%) are male, and 199 patients (74.25%) are female. 164 patients (61.2%) are aged 60-75 years old. It is found that 1 case (0.37%) has the drug-related problem of drug overdose and as many as 34 cases (12.69%) have potential drug interactions.

scholarly journals Evidence for Training-Induced Changes in miRNA Levels in the Skeletal Muscle of Patients With Type 2 Diabetes Mellitus

2020 ◽  
Vol 11 ◽  
Author(s):  
Sarah Simaitis ◽  
Benedikt Schulte-Körne ◽  
Thorsten Schiffer ◽  
Wilhelm Bloch ◽  
Hans-Georg Predel ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Skeletal Muscle ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Resistance Index ◽  
Micro Rnas ◽  
Study Results

Physical training can improve glycemic control in patients with type 2 diabetes mellitus (T2DM). However, the underlying mechanisms are not entirely clear. An interesting piece of the puzzle could be the regulation of micro-RNAs (miRNAs). They are important modulators of protein expression. Some miRNAs were found to be both linked to poor glycemic control/insulin resistance (with evidence from in vivo and/or in vitro studies) and dysregulated in the skeletal muscle of T2DM patients. This pilot study examines whether a 3-month endurance training program [three times a week, 70–80% peak heart rate (HRpeak)] can down-regulate their levels in T2DM men (n = 7). One skeletal muscle biopsy sample was obtained from each patient at T1 (6 weeks pre-intervention), one at T2 (1 week pre-intervention) and one at T3 (3–4 days post-intervention). miRNA-27a-3p, −29a-3p, −29b-3p, −29c-3p, −106b-5p, −135a-5p, −143-3p, −144-3p, −194-5p, and − 206 levels were determined by RT-qPCR. Friedman ANOVA and post-hoc tests showed that miRNA-29b-3p, −29c-3p and -135a-5p levels were significantly reduced post-training (T3 vs. T2 and/or T1). Glycated hemoglobin (HbA1c) and HOMA insulin resistance index did not change significantly. However, HbA1c was reduced in 6 of 7 patients post-training. Furthermore, Spearman’s rank correlation analyses with all values from all time points showed significant negative associations between miRNA-29c-3p, −106b-5p, −144-3p and −194-5p levels and cardiorespiratory fitness (VO2peak). The study results imply that regular exercise and improving one’s physical fitness is helpful for the regulation of skeletal muscle miRNAs in T2DM patients. Whether or not changes in the miRNA profile can affect the clinical situation of T2DM patients warrants further research.

scholarly journals Knowledge and Experience of Community Health Volunteer (Cadre) on Type 2 Diabetes Mellitus Management in Yogyakarta

2021 ◽  
Vol 9 (T4) ◽  
pp. 240-244
Author(s):  
Yanuar Primanda ◽  
Desy Ivani Fatah
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Health Care ◽  
Type 2 Diabetes Mellitus ◽  
Community Health ◽  
Care Center ◽  
Cross Sectional ◽  
Health Care Center ◽  
Comprehensive Management

BACKGROUND: Type 2 diabetes mellitus (T2DM) is a chronic disease that requires long-term and comprehensive management. People with T2DM play a significant role in managing their condition and day-to-day life adjustment related to T2DM. In the Indonesian context, community health volunteers (cadres) roles are imperative because the community can influence day-to-day health care. AIM: The study aimed to describe the knowledge and experience of cadre on T2DM management in Yogyakarta, Indonesia. METHODS: It was a descriptive study with a cross-sectional approach. Five primary health-care center (Puskesmas) areas in Bantul district were selected based on their high population, including Kasihan 2, Jetis 1, Sedayu 1, Jetis 2, and Imogiri 2 areas. Sixty-eight cadres from those five areas were enrolled in this study through accidental sampling. The data were collected using questionnaires and analyzed using descriptive statistics. RESULTS: The results showed that the average age of cadres was 43 years old (20–64 years), with more than half of them graduating from high school, unemployed (61.8%), and never received education about DM and its management (51.5%). Forty-two cadres (61.8%) had a moderate level of knowledge, and 64.7% had inadequate experience in T2DM management. CONCLUSION: Knowledge and experience of cadre regarding T2DM management in Yogyakarta need to be increased. Further research is needed to examine certain training programs’ effects to improve cadre’s knowledge and experience in T2DM.

Comparison of E-Consults and Face-to-Face Care on Costs and Glycemic Control among Veterans with Type 2 Diabetes Mellitus

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 137-LB ◽  
Author(s):  
NEHA KARAJGIKAR ◽  
KARLA B. DETOYA ◽  
JANICE N. BEATTIE ◽  
STACEY J. LUTZ-MCCAIN ◽  
MONIQUE Y. BOUDREAUX-KELLY ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Face To Face

90-LB: Treatments and Trends in Glycemic Control for Patients with Type 2 Diabetes Mellitus Treatment following Metformin

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 90-LB
Author(s):  
SANJAY K. BAJPAI ◽  
RADHIKA NAIR ◽  
TICH CHANGAMIRE ◽  
RICHARD SHEER ◽  
QIANQIAN WANG ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Diabetes Mellitus Treatment
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