scholarly journals The relationship between the TSH values and the Tpeak – Tend interval duration in hypothyroid patients receiving Levothyroxine treatment

2019 ◽  
Vol 57 (2) ◽  
pp. 175-180
Author(s):  
Hüseyin Avni Findikli ◽  
Ayşe Şahin Tutak ◽  
Hakan Aydin
Keyword(s):  
Hormone Level ◽  
Cross Sectional Study ◽  
Healthy Individuals ◽  
Sectional Study ◽  
Control Groups ◽  
Cross Sectional ◽  
And Control ◽  
The Relationship ◽  
Hypothyroid Patients ◽  
Levothyroxine Treatment

Abstract Introduction. Changes in thyroid hormone level can affect the cardiovascular system. The aim of this study was to show how the Tpeak -Tend (Tpe) interval, which is a new marker of ventricular arrythmia, is affected in patients who have become euthyroid following Levothyroxine treatment for hypothyroidism, as this has not been examined previously in literature. Materials and Methods. This, cross-sectional study included a total of 119 females aged 18-45 years, separated into 3 groups as hypothyroid, euthyroid and control groups. For evaluation of the QTc and Tpe intervals, examination on precordial V5 lead was made of all the ECGs taken routinely on presentation of the patients. Results. The Tpe and QTc intervals of the hypothyroid group were determined to be significantly prolonged compared to those of the euthyroid and control groups (p < 0.001) and the values of the euthyroid and control groups were similar. A positive correlation was determined between TSH levels and Tpe and QTc intervals. Tpe interval AUC = 0.801 (%95 CI: 0.719 – 0.884) was higher than that of QTc AUC = 0.689 (%95 CI: 0.591 – 0.786). Conclusions. The Tpe duration was evaluated in respect of the risk of arrythmia in hypothyroid patients. In patients who had become euthyroid, the Tpe interval was found to be similar to that of healthy individuals and was more predictive than QTc. In the light of these findings it can be recommended that measurement of the Tpe interval should be preferred to QTc as a marker of the arrythmogenic effect in hypothyroid patients.

scholarly journals Alteration of Screw-home Movement in Patients With Knee Osteoarthritis: A Cross-sectional Study

2020 ◽  
Author(s):  
Jeongwoo Jeon ◽  
Dongyeop Lee ◽  
Jaeho Yu ◽  
Jinseop Kim ◽  
Sang Hoon Lhee ◽  
...  
Keyword(s):  
Knee Osteoarthritis ◽  
Knee Extension ◽  
Cross Sectional Study ◽  
Measurement Unit ◽  
Tibial Rotation ◽  
Sectional Study ◽  
Control Groups ◽  
Cross Sectional ◽  
Knee Oa ◽  
And Control

Abstract Background: Tibial rotation accompanying sagittal movement contains the phenomenon of screw-home movement of the knee, which plays an important role in knee stability during extension. This study aimed to investigate the alteration of screw-home movement in patients with knee osteoarthritis (OA).Methods: Participants (n =67) in this cross-sectional study were outpatients in the department of orthopedics of a general hospital and included patients with knee OA (n=31) and asymptomatic control subjects (n=36).Knee kinematic data were measured using an inertial measurement unit. The total tibial rotation was obtainedduring knee sagittal movement. The acquired angle of tibial rotation was divided into four periodseach extension and flexion. The total tibial rotation and the variation of each period were compared between the OA and control groups.Results: Significant differences arose between the OA and control groups in the total tibial rotation during knee extension and flexion(P< 0.001).The variation of tibial rotation was also significantly different between groups for all periods (P< 0.001; knee extensionat 70° to 45°,P = 0.014).Conclusions: We found a reduction in the total tibial rotation and loss of the screw-home movement in the unloaded OA knee. To normalize the screw-home movement, it is necessary to promote proper articular movement of the knee joint and suppress the hyperexcitability of the medial muscles.

scholarly journals TUBERCULOUS PATIENTS;

2013 ◽  
Vol 20 (05) ◽  
pp. 678-683
Author(s):  
NASIR AZIZ ◽  
HAMID MAHMOOD ◽  
HASHIM RIAZ ◽  
Zahid Mahmood ◽  
Akhtar Murad Qadir ◽  
...  
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Control Groups ◽  
Cross Sectional ◽  
Bcg Vaccination ◽  
Household Contacts ◽  
Study Materials ◽  
Significant Difference ◽  
Immune Globulins ◽  
And Control

Objective: This study was designed to analyze the BCG vaccination status and compare the immune globulins levels in thehousehold contacts of tuberculous patients with non contacts of unexposed healthy peoples. Place: Gulab Devi Hospital, Post GraduateMedical Institute and Defense Housing Authority Lahore. Study design: Cross sectional study. Materials and Methods: Investigationslike ESR were done and the sera of 200 persons included in the study were tested for anti tuberculous antibodies by ELISA. BCGvaccination present or absent and scars were positive or negative in both groups were included. Results: The combined serologicalpositivity of the household contacts was 65.8% and for non-contacts was 34.1%. BCG scars were mostly absent in the householdcontacts as well as in non-contacts; But statistically IgG and IgA were present significantly by higher number in the household contacts ascompared to non-contacts, where as no significant difference in the IgM levels. These immunoglobulins status were compared with BCGscars in both study and control groups. The results were analyzed by SPSS version 14. Conclusions: Household contacts of tuberculosispatients are more susceptible to tuberculosis as compared to the non-contacts, as shown by positive and negative status ofantituberculous antibodies in the house hold contacts. More over BCG vaccination has no significant role in humoral evaluation.

scholarly journals Headache in recent onset hypothyroidism: Prevalence, characteristics and outcome after treatment with levothyroxine

Cephalalgia ◽  
2016 ◽  
Vol 37 (10) ◽  
pp. 938-946 ◽  
Author(s):  
Marise de Farias Lima Carvalho ◽  
Josian Silva de Medeiros ◽  
Marcelo Moraes Valença
Keyword(s):  
Subclinical Hypothyroidism ◽  
Posterior Part ◽  
Cross Sectional Study ◽  
Overt Hypothyroidism ◽  
Sectional Study ◽  
Cross Sectional ◽  
Recent Onset ◽  
Severe Intensity ◽  
Hypothyroid Patients ◽  
Levothyroxine Treatment

Objective The objective of this article is to analyze the features of headache attributed to hypothyroidism (HAH), evaluate the differences between groups with and without HAH, between “overt” and “subclinical” hypothyroidism groups, and evaluate outcomes after levothyroxine treatment. Methods Patients with hypothyroidism were selected in a cross-sectional study, followed prospectively for 12 months, and classified as subclinical or overt hypothyroidism. The patients were divided into two groups: with and without HAH. Results HAH was reported by 73/213 (34%) patients, involving the following areas: fronto-orbital (49%), temporal (37%), and posterior part of the head (15%). The HAH features were as follows: pulsatile (63%), four to 72 hours’ duration (78%), unilateral (47%), nausea/vomiting (60%), and moderate-severe intensity (72%). Hypothyroidism symptomatology was similar in both groups, except for a greater frequency of hoarseness in the group with HAH. Migraine history was more frequent in the patients with HAH (53% vs 38%, p < 0.05). The frequency of HAH was similar both in overt and subclinical hypothyroidism. After levothyroxine treatment 78% reported a decrease in HAH frequency. Subclinical and overt hypothyroid patients reported a similar alleviation of their headaches. Conclusion Patients with HAH may present with unilateral, pulsatile, episodic pattern, and nausea/vomiting, which is at odds with the criteria for HAH established by ICHD 3 beta. Not all individuals responded to levothyroxine, and patients with the subclinical form of hypothyroidism benefit from this treatment.

scholarly journals Designing an Annual Educational Calendar of Medical Parasitology Based on Training Weeks

2019 ◽  
Vol 8 (2) ◽  
pp. 90-94
Author(s):  
Mitra Salehi ◽  
Amirreza Nasirzadeh ◽  
Hamid Reza Niazkar ◽  
Kokab Basiri Moghaddam
Keyword(s):  
Cross Sectional Study ◽  
Sectional Study ◽  
Teaching Session ◽  
Medical Sciences ◽  
Control Groups ◽  
Cross Sectional ◽  
Quality Of Teaching ◽  
The Mean ◽  
And Control

Background: Parasitology is a course filled with many complicated terminologies. In this study, a guide was designed to facilitate the learning of parasitology. More precisely, an annual educational calendar of medical parasitology was designed based on the weeks of education and its effectiveness was assessed in university students of medical sciences. Materials and Methods: This cross-sectional study included 174 students who were randomly divided into two intervention and control groups. At the baseline, the students were tested with a questionnaire at the beginning of each teaching session and the end of the intervention. In addition, another questionnaire was used to compare the attitude and satisfaction of students in two groups. Finally, the scores of the students were entered in SPSS 16 for analysis. Results: The results of parametric tests showed that the mean scores of laboratory and medical students during several tests in different sessions were significantly different in the two groups. Conclusion: The educational calendar is a new method in medical education, especially in the field of medical parasitology. This calendar as an educational supplement, emphasizes on students’ active learning and contributes to improving the quality of teaching the parasitology course in addition to meeting their educational needs.

PHYSICAL DISORDERS AFTER HYSTERECTOMY DEPEND ON MRS AND SERUM ESTRADIOL LEVELS

2016 ◽  
pp. 41-45
Author(s):  
Lam Huong Le
Keyword(s):  
Key Words ◽  
Cross Sectional Study ◽  
Sexual Disorders ◽  
Serum Estradiol ◽  
Sectional Study ◽  
Cross Sectional ◽  
Total Hysterectomy ◽  
Physical Disorders ◽  
The Relationship ◽  
Estradiol Levels

Objectives: To study the relationship between serum estradiol and physical disorders after hysterectomy. Methods: A descriptive cross sectional study on 151 women after total hysterectomy from 12/2008 to 11/2010 at Hue Cental Hospial. Results: Serious disorders in total hysterectomy group include: physical disorders (34.78%), maternal disorders (71.74%), sexual disorders (58.70%). There were significant differences these disorders between total hysterectomy group and hysterectomy with/without accessiory remove group, as well as menopause group. Conclusion: Serum estradiol levels was inversely correlated with physical disorders, martenal disorders, sexual disorders and other disorders. Key words: hysterectomy, serum estradiol

POLA ASUH ORANGTUA TERHADAP TINGKAT KEMANDIRIAN PERSONAL HYGIENE CUCI TANGAN DAN GOSOK GIGI PADA ANAK PRASEKOLAH

2020 ◽  
Vol 15 (2) ◽  
pp. 200-205
Author(s):  
Dina Dewi Anggraini
Keyword(s):  
Survey Research ◽  
Quantitative Study ◽  
Parenting Style ◽  
Cross Sectional Study ◽  
Personal Hygiene ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Test Analysis ◽  
The Relationship

ABSTRACT   The study aims todetermine the relationship between parenting style and the level of independence of Personal Hygiene Hand Wasting and Tooth Brush in Preschoolers in Kindergarten Negeri Pembina Blora in 2019. The study is a quantitative study, based on the research location including the type of field reseaerch, based on the ansence of the treatment of subjects including survey research, based on time is a cross sectional study, and based on objectives includin correlation analytics. The population in this study were all parents in Kindergarten Negeri Pembina Blora as many as 85 respondents. Based on the sample calculation, the sample obtained in this study that most parent in Kindergarten Negeri Pembina Blora amounted to 70 respondents. Srearmen’s rho test analysis results parenting parents with the level of independence of personal hygiene hand wasting result obtained p value = 0,000 < α (0,05), and parenting patters with the independence of personal hygiene tooth brush obtained results p value = 0,000 < α (0,05). So it can be concluded that were is a significant relationship between parenting parents with the level of independence of personal hygiene washing hands and brushing their tooth at preschoolers in Kindergarten Negeri Pembina Blora in 2019. Keywords: parenting; personal hygiene, preschool ABSTRAK   Penelitian ini bertujuan untuk mengetahui Hubungan Pola Asuh Orangtua Terhadap Tingkat Kemandirian Personal Hygiene Cuci Tangan dan Gogok Gigi pada Anak Prasekolah di TK Negeri Pembina Blora Tahun 2019. Penelitian ini adalah penelitian kuantitatif, berdasarkan tempat penelitian termasuk jenis penelitian lapangan, berdasarkan tidak adanya perlakuan terhadap subjek termasuk penelitian survey, berdasarkan waktu merupakan penelitian cross sectional, dan berdasarkan tujuan termasuk analitik korelasi. Populasi dalam penelitian ini adalah seluruh orangtua di TK Negeri Pembina Blora sebanyak 85 responden. Berdasarkan perhitungan sampel  maka diperoleh sampel pada penelitian ini adalah sebagian orangtua di TK Negeri Pembina Blora sebanyak 70 responden. Hasil analisis uji spearmen’s rho pola asuh orangtua dengan tingkat kemandirian personal hygiene cuci tangan didapatkan hasil p value = 0,000 < α (0,05), dan pola asuh orangtua dengan kemandirian personal hygiene gosok gigi didapatkan hasil p value = 0,000 < α (0,05). Sehingga dapat disimpulkan bahwa ada hubungan yang signifikan antara pola asuh orang tua dengan tingkat kemandirian personal hygiene cuci tangan dan gosok gigi pada anak prasekolah di TK Negeri Pembina Blora Tahun 2019. Kata kunci: pola asuh; personal hygiene; prasekolah

The effect of type of water supply on water quality in a developing community in South Africa

1997 ◽  
Vol 35 (11-12) ◽  
pp. 35-40 ◽  
Author(s):  
B. Genthe ◽  
N. Strauss ◽  
J. Seager ◽  
C. Vundule ◽  
F. Maforah ◽  
...  
Keyword(s):  
Water Quality ◽  
Water Supply ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
E Coli ◽  
Guideline Values ◽  
Developing Communities ◽  
Quality Guideline ◽  
And Control ◽  
The Relationship

Efforts to provide water to developing communities in South Africa have resulted in various types of water supplies being used. This study examined the relationship between the type of water supply and the quality of water used. Source (communal taps, private outdoor and indoor taps) and point-of-use water samples were examined for heterotrophic plate counts (HPC), total and faecal coliforms, E. coli, and coliphages. Ten percent of samples were also analysed for enteric viruses, Giardia and Cryptosporidium. Approximately 320 households were included in a case-control study. In addition, a cross-sectional study was conducted. Both studies examined the relationship between different types of water facilities and diarrhoea among pre-school children. The source water was of good microbial quality, but water quality was found to have deteriorated significantly after handling and storage in both case and control households, exceeding drinking water quality guideline values by 1-6 orders of magnitude. Coliphage counts were low for all water samples tested. Enteric viruses and Cryptosporidium oocysts were not detected. Giardia cysts were detected on one occasion in case and control in-house samples. Comparisons of whether in-house water, after handling and storage, complied with water quality guideline values demonstrated households using communal taps to have significantly poorer quality than households using private outdoor or indoor taps for HPC and E. coli (χ2 = 14.9, P = 0.001; χ2 = 6.6, P = 0.04 respectively). A similar trend (although not statistically significant) was observed for the other microbial indicators. The cross-sectional study demonstrated an apparent decrease in health risk associated with private outdoor taps in comparison to communal taps. This study suggests that a private outdoor tap is the minimum level of water supply in order to ensure the supply of safe water to developing communities.

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