scholarly journals Advanced lung cancer in combination with liver echinococcosis

2021 ◽  
Vol 25 (2) ◽  
pp. 124-132
Author(s):  
A. B. Egorkina ◽  
Yu. A. Stepanova ◽  
G. G. Karmazanovsky ◽  
D. V. Kalinin ◽  
A. V. Zhao
Keyword(s):  
Lung Cancer ◽  
Diagnostic Errors ◽  
Final Diagnosis ◽  
Advanced Lung Cancer ◽  
Surgical Operation ◽  
Radiation Imaging ◽  
Poorly Differentiated ◽  
Distant Spread ◽  
The Right ◽  
Immunohistochemical Studies

Presented clinical case is a rare case of poorly differentiated squamous cell non-keratinizing cancer of the right lung with ingrowth into the diaphragm and liver, metastatic liver damage in combination with recurrent echinococcosis of the liver. Taking into account the epidemiological history, the surgery, the features of radiation imaging and the results of serology in the preoperative period, the diagnosis of “echinococcosis of the liver with spread to the lungs” was made, which turned out to be incorrect. The diagnosis during the surgical operation was changed, but also turned out to be incorrect. The final diagnosis was made only on the basis of histological and immunohistochemical studies.The reasons of diagnostic errors are analyzed, the emphasis is made on the criteria of differential diagnosis. Typical features of visualization of liver echinococcosis, lung cancer with local and distant spread are presented.

scholarly journals Recurrent Intrathoracic Locking of the Scapula after Lung Cancer Resection and Combined Rib Resection

2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Akinori Kimura ◽  
Hideyuki Sasanuma ◽  
Takashi Ajiki ◽  
Hitoshi Sekiya ◽  
Katsushi Takeshita
Keyword(s):  
Lung Cancer ◽  
Spindle Cell ◽  
Three Dimensional ◽  
Spindle Cell Carcinoma ◽  
Primary Lesion ◽  
Thoracic Wall ◽  
Advanced Lung Cancer ◽  
Lung Lobectomy ◽  
Thoracic Wall Resection ◽  
The Right

We report a case of recurrent locking of the scapula in the thorax after combined lobectomy and thoracic wall resection for advanced lung cancer. The patient was a 52-year-old man with advanced spindle cell carcinoma in his right lung. He had undergone right lung lobectomy and thoracic wall excision (Th1–5). Intrathoracic repair had not been performed to address the defect in the thoracic wall. Two months after the operation he experienced sudden acute pain in the right shoulder. Three-dimensional computed tomography revealed locking of the scapula intrathoracically. The diagnosis was recurrent locking of the scapula in the thorax. He underwent conservative treatment. Because his symptoms were not alleviated and he continued to experience recurrent locking, we performed partial resection of the inferior part of the scapula. Although scapular locking diminished after this procedure, there were still some pain and “catching” between the scapula and the thoracic wall (T6) when he undertook certain movements. No further surgery could be performed, however, because the cancer from the primary lesion had recurred near the previously operated thoracic wall. A procedure for recurrent intrathoracic locking of the scapula was not successful in this case.

Carcinoma Showing Thymus-like Differentiation (CASTLE) with Synchronous Papillary Thyroid Carcinoma: A Case Report and Review

2021 ◽  
pp. 014556132110601
Author(s):  
Yuan-Chin Hsu ◽  
Chuen Hsueh ◽  
Wan-Ni Lin ◽  
Tsung-You Tsai ◽  
Shih-Yuan Hung ◽  
...  
Keyword(s):  
Papillary Thyroid Carcinoma ◽  
Thyroid Carcinoma ◽  
Final Diagnosis ◽  
Vocal Cord Palsy ◽  
Anaplastic Thyroid Carcinoma ◽  
Papillary Thyroid ◽  
Thyroid Cancers ◽  
Central Lymph Node Dissection ◽  
The Right ◽  
Immunohistochemical Studies

Carcinoma showing thymus-like differentiation (CASTLE) is a rare malignant tumor that accounts for 0.1%–0.15% of all thyroid cancers. More than half of the patients have tumor extension to adjacent organs, including the recurrent laryngeal nerve, trachea, and esophagus. The diagnosis of CASTLE is based on histology and immunohistochemistry. A 58-year-old female patient complained of hoarseness for one and half years. Right side vocal cord palsy was diagnosed by fiberscopy. Thyroid sonography revealed right thyroid tumors, which were reported to be papillary thyroid carcinoma through FNAC. Total thyroidectomy with central lymph node dissection was performed. Pathologist found 2 isolated malignancy tumors. One patient in the right thyroid lobe had papillary thyroid carcinoma features. The other extrathyroid tumor seemed to be separated from the first tumor and invaded the thyroid capsule. After multiple immunohistochemical studies, PTC synchronous CASTLE was the final diagnosis. Coexisting PTC and CASTLE is very rare. This is the first report to describe a case showing PTC at first, while subsequent pathologic examination revealed the presence of CASTLE in addition to PTC. Since the prognosis of CASTLE is favorable, the treatment is different from other aggressive thyroid cancers, such as poorly differentiated or anaplastic thyroid carcinoma.

Evaluation of advanced lung cancer inflammation as potential prognostic markers in patients with colorectal cancer.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e15142-e15142
Author(s):  
Julie Haewon Rowe ◽  
Fathima Kamil ◽  
Andre Yu ◽  
Curtis Jackson Wray ◽  
Putao Cen ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Logistic Regression ◽  
Survival Rates ◽  
Prognostic Index ◽  
Advanced Lung Cancer ◽  
Cancer Center ◽  
Logistic Regression Models ◽  
Colon Cancers ◽  
Cancer Inflammation ◽  
The Right

e15142 Background: The Advanced Lung cancer Inflammation (ALI) prognostic index evaluates the degree of systemic inflammation in cancer patients and has been validated in small cell lung and esophageal cancer. The “sidedness” of the colon primary has prognostic implications with left sided tumors having longer survival rates than right sided. Our hypothesis is that right sided colorectal cancers (CRC) will have a lower ALI. Methods: We conducted a retrospective review of newly diagnosed CRC patients who were seen and evaluated at a tertiary Cancer Center from 1/1/2005 to 12/31/2015. ALI is calculated as ALI = BMI x (serum albumin/NLR). NLR is the neutrophil to lymphocyte ratio. Logistic regression models were used to determine the association between primary colon cancer location and ALI. Results: A total of 279 patients were included in this study. 53% of patients were male and mean age was 63.4 years (SD 13.7). 52% of cancers were located on the right side. Using an ordered logistic regression, ALI was predictive of higher stage disease (p = 0.04). In those patients with stage III (n = 64) or IV (n = 136) disease, the likelihood of a low ALI was significantly higher for right-sided colon cancers (OR 2.12, 95%CI:1.18-7.76). Conclusions: The Advanced Lung Cancer Inflammation index appears to be related to both CRC stage and primary cancer location. Ongoing studies are needed to determine the relationship between ALI and CRC survival.

Salvage surgery for lung cancer with tracheo-oesophageal fistula during concurrent chemoradiotherapy

2019 ◽  
Vol 29 (4) ◽  
pp. 641-643
Author(s):  
Isamu Watanabe ◽  
Kazuya Takamochi ◽  
Shiaki Oh ◽  
Kenji Suzuki
Keyword(s):  
Lung Cancer ◽  
Concurrent Chemoradiotherapy ◽  
Salvage Surgery ◽  
Mediastinal Lymph Node ◽  
Advanced Lung Cancer ◽  
Recurrent Nerve ◽  
Recurrent Nerve Palsy ◽  
Initial Surgery ◽  
The Right ◽  
Staged Reconstruction

Abstract A 48-year-old man presenting with cough, dysphagia and chest pain was diagnosed with advanced inoperable squamous cell carcinoma located in the right S2 with mediastinal lymph node metastases invading the oesophagus (c-T4N2M0 stage IIIB). Concurrent chemoradiotherapy (66 Gy) was planned, but he developed a tracheo-oesophageal fistula during the chemoradiotherapy course (26 Gy). A right sleeve pneumonectomy with oesophagectomy, cervical oesophagostomy and enterostomy were performed. Although bilateral recurrent nerve palsy occurred, he recovered via enhanced rehabilitation and was discharged 28 days after the salvage surgery. Three months after the initial surgery, staged reconstruction surgery of the stomach was performed. Intensive rehabilitation resulted in restored swallowing ability. He is alive with recurrent disease 12 months after surgery. This is the first report of salvage surgery for advanced lung cancer with tracheo-oesophageal fistula during concurrent chemoradiotherapy.

scholarly journals A case of multiple pulmonary nodules diagnosed as pulmonary melanoma without extra-pulmonary site

2021 ◽  
Vol 8 (1) ◽  
pp. 1
Author(s):  
Yoshihiro Miyashita ◽  
Miyuki Kobayashi ◽  
Yumiko Kakizaki ◽  
Toshiharu Tsutsui ◽  
Takashi Kumagai ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Primary Lung Cancer ◽  
Pulmonary Nodules ◽  
Final Diagnosis ◽  
Tumor Biopsy ◽  
Annual Screening ◽  
Nodular Lesions ◽  
Extra Pulmonary ◽  
The Right ◽  
Pulmonary Sarcoma

A 67-year-old patient visited the hospital for the evaluation of pulmonary nodular lesions detected in his chest radiograph duringan annual screening. He was asymptomatic and transbronchial tumor biopsy of the nodule in the right upper lobe revealed features of pulmonary sarcoma, which did not resemble any of the histolopathological categories of primary lung cancer. A positive immunological staining for both HMB-45 and Melan-A resulted in the final diagnosis of melanoma. It is important for a respiratory clinician to remind the possibility of a melanoma, when tumors cannot be histopathologically classified under any of the categories of primary lung cancer.

scholarly journals CS-6 A case of poorly differentiated chordoma with systemic metastasis

2021 ◽  
Vol 3 (Supplement_6) ◽  
pp. vi28-vi28
Author(s):  
Naoki Shinojima ◽  
Keisuke Harada ◽  
Yuji Dekita ◽  
Haruaki Yamamoto ◽  
Mai Itouyama ◽  
...  
Keyword(s):  
Tumor Resection ◽  
Residual Tumor ◽  
Final Diagnosis ◽  
High Dose ◽  
Local Doctor ◽  
Short Period ◽  
Systemic Metastasis ◽  
Poorly Differentiated ◽  
The Right ◽  
Pterygoid Muscles

Abstract A case report: The patient was a 32-year-old man with diplopia. He was diagnosed as sphenoid sinusitis on MRI by a local doctor and visited an otolaryngologist. MRI showed extensive extension of neoplastic lesions from the clivus to the sphenoid sinus to the anterior ethmoid sinuses, bilateral cavernous sinuses, and the right medial and lateral pterygoid muscles. The right Lebiere’s lymph node was enlarged and thought to be a metastatic site. Based on the rapid growth and extension of the tumor, the patient was referred to the Department of Otolaryngology at our hospital on suspicion of sinonasal carcinoma. The possibility of chordoma could not be denied, so the patient was referred to our department. The patient underwent a joint endoscopic extended transsphenoidal tumor resection. The pathological diagnosis showed mitotic and necrotic features, and the majority of the cells showed highly atypical components without mucous substrate. However, brachyury, a marker for chordoma, was diffusely positive, and there was loss of INI1 (SMARCB1) expression. The final diagnosis was poorly differentiated chordoma. Postoperatively, the tumor in the right cavernous sinus grew rapidly, and the right eye became blind due to obstruction of the superior ophthalmic vein. The patient was treated with Gamma Knife as soon as possible in the hope of local control by high-dose irradiation, and after a total of three irradiations, the residual tumor shrank markedly and symptoms improved, but systemic metastasis occurred in a short period of time and the patient died. The number of cases of poorly differentiated chordoma has been reported rarely (more than 50), and it is more common in children and even rarer in adults. We report this case with a review of the literature.

scholarly journals Not COVID-19, Don’t Overlook Pneumocystis in Patients on Gefitinib!

2021 ◽  
Vol 28 (1) ◽  
pp. 961-964
Author(s):  
Jérémy Barben ◽  
Valérie Quipourt ◽  
Jérémie Vovelle ◽  
Alain Putot ◽  
Patrick Manckoundia
Keyword(s):  
Computed Tomography ◽  
Lung Cancer ◽  
Final Diagnosis ◽  
Pneumocystis Jirovecii ◽  
Advanced Lung Cancer ◽  
Pneumocystis Jirovecii Pneumonia ◽  
Emergency Unit ◽  
Rt Pcr ◽  
Chest Computed Tomography ◽  
Small Molecule Therapeutics

An 82-year-old woman treated for advanced lung cancer with gefitinb was admitted to the emergency unit complaining of dyspnea. Chest computed tomography found abnormalities classified as possible diffuse COVID-19 pneumonia. RT-PCR for Sars-Cov-2 was twice negative. PCR for Pneumocystis jirovecii was positive on bronchoalveolar lavage. The final diagnosis was Pneumocystis jirovecii pneumonia. Therefore, physicians must be careful not to misdiagnose COVID-19, especially in cancer patients on small-molecule therapeutics like gefitinib and corticosteroids.

scholarly journals A 60 Years Old Man with Adenocarcinoma of Colon and Lung with an Isolated Adrenal Metastasis: A Case Report

2021 ◽  
Vol 9 (1) ◽  
pp. 30-37
Author(s):  
Netay Kumer Sharma ◽  
Sankar Narayan Dey ◽  
Md Masudur Rahman ◽  
Mahzabeen Islam ◽  
- Mukthadira ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Radical Resection ◽  
Metastatic Carcinoma ◽  
Adrenal Metastasis ◽  
Pathological Examination ◽  
Ascending Colon ◽  
Postoperative Adjuvant Chemotherapy ◽  
Poorly Differentiated Adenocarcinoma ◽  
Poorly Differentiated ◽  
The Right

The incidence of synchronous colorectal and lung cancer associated with adrenal metastasis is relatively rare. We report of patient with tumour located in the right colic flexure adjoining ascending colon, mid and partly upper lobe of right lung. Pathological examination showed the colorectal and lung cancer were poorly differentiated adenocarcinoma. Right adrenal mass was adrenocortical metastatic carcinoma. Surgical treatment and postoperative adjuvant chemotherapy for the lung cancer were different from those for colorectal cancer with pulmonary metastasis. If possible, radical resection should be performed for each cancer when synchronicity is found. CBMJ 2020 January: Vol. 09 No. 01 P: 30-37

scholarly journals Clinical Management of Pain in Advanced Lung Cancer

2012 ◽  
Vol 6 ◽  
pp. CMO.S8360 ◽  
Author(s):  
Claribel P.L. Simmons ◽  
Nicholas Macleod ◽  
Barry J.A. Laird
Keyword(s):  
Lung Cancer ◽  
Pain Management ◽  
World Health ◽  
Advanced Lung Cancer ◽  
Common Symptom ◽  
Cancer Symptoms ◽  
Anti Cancer ◽  
The World ◽  
Distant Spread ◽  
Cancer Experience

Lung cancer is the most common cancer in the world and pain is its most common symptom. Pain can be brought about by several different causes including local effects of the tumor, regional or distant spread of the tumor, or from anti-cancer treatment. Patients with lung cancer experience more symptom distress than patients with other types of cancer. Symptoms such as pain may be associated with worsening of other symptoms and may affect quality of life. Pain management adheres to the principles set out by the World Health Organization's analgesic ladder along with adjuvant analgesics. As pain can be caused by multiple factors, its treatment requires pharmacological and non-pharmacological measures from a multidisciplinary team linked in with specialist palliative pain management. This review article examines pain management in lung cancer.

scholarly journals Lung Cancer Presenting as Skin Metastasis of the Back and Hand: A Case Series and Literature Review

2019 ◽  
Vol 12 (2) ◽  
pp. 480-487 ◽  
Author(s):  
Misbahuddin Khaja ◽  
Daniel Mundt ◽  
Rizwan Ahmed Dudekula ◽  
Umair Ashraf ◽  
Shehriyar Mehershahi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Ct Scan ◽  
Left Lung ◽  
Case Series ◽  
The United States ◽  
Middle Lobe ◽  
Skin Metastasis ◽  
Smoking History ◽  
Poorly Differentiated ◽  
The Right

Lung cancer has the highest mortality of all cancers in the United States. The incidence of lung cancer with metastases to the skin varies between 1–12%, with the highest incidence seen in men. Here, we present two cases of lung cancer presenting as skin metastasis. The first patient was an 80-year-old African American male who presented to the hospital for evaluation of a right upper back mass. A few months prior to admission, he was found to have a left lung mass on CT scan of the chest, he underwent biopsy which showed poorly differentiated SCC of the lung. He also had a skin biopsy which showed poorly differentiated carcinoma in the dermis consistent with metastatic SCC. He was started on chemotherapy, but could not tolerate it. He was accepted to hospice. The second patient was a 78-year-old Hispanic female who presented to the hospital with dyspnea, and a dry cough. Upon physical examination, a 2 × 2 cm ulcerated, wart-like nodule on the right palm was noted. Subsequent CT scan of the chest showed a partial collapse of the right middle lobe. A biopsy of the hand mass revealed well-to-moderately differentiated metastatic SCC favoring lung origin. A bronchoscopy biopsy showed invasive SCC. Subsequently her condition worsened and she passed away. Metastasis to the skin is an unusual presenting symptom of lung cancer. It is therefore essential to consider metastasis as a diagnosis in a patient with both a skin lesion and a smoking history.

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