Hospital Admission Related Factors of Pediatric Asthmatic Patients

2022 ◽  
pp. 1
Author(s):  
Sara Abed ◽  
Israa Malli ◽  
Hassan AlSubaie ◽  
Raad Alharbi ◽  
Shakr Alwani ◽  
...  
Keyword(s):  
Hospital Admission ◽  
Related Factors ◽  
Asthmatic Patients

scholarly journals The impact of COVID-19 on patients with asthma

2020 ◽  
Author(s):  
Jose Luis Izquierdo ◽  
Carlos Almonacid ◽  
Yolanda Gonzalez ◽  
Carlos Del Rio-Bermudez ◽  
Julio Ancochea ◽  
...  
Keyword(s):  
Hospital Admission ◽  
Inhaled Corticosteroids ◽  
Big Data Analytics ◽  
Related Factors ◽  
Asthmatic Patients ◽  
Admission Rates ◽  
Increased Risk ◽  
Predominantly Female ◽  
The Impact ◽  
Diabetes And Obesity

Background: From the onset of the COVID-19 pandemic, an association between the severity of COVID-19 and the presence of certain medical chronic conditions has been suggested. However, unlike influenza and other viruses, the burden of the disease in patients with asthma has been less evident. Objective: This study aims at a better understanding of the burden of COVID-19 in patients with asthma and the impact of asthma, its related comorbidities, and treatment on the prognosis of COVID-19. Methods: We analyzed clinical data from patients with asthma from January 1st to May 10th, 2020 using big data analytics and artificial intelligence through the SAVANA Manager clinical platform. Results: Out of 71,192 patients with asthma, 1,006 (1.41%) suffered from COVID-19. Compared to asthmatic individuals without COVID-19, patients with asthma and COVID-19 were significantly older (55 vs. 42 years), predominantly female (66% vs. 59%), had higher prevalence of hypertension, dyslipidemias, diabetes, and obesity, and smoked more frequently. Contrarily, allergy-related factors such as rhinitis and eczema were less frequent in asthmatic patients with COVID-19 (P < .001). Higher prevalence of hypertension, dyslipidemia, diabetes, and obesity was also confirmed in those patients with asthma and COVID-19 who required hospital admission. The percentage of individuals using inhaled corticosteroids (ICS) was lower in patients who required hospitalization due to COVID-19, as compared to non-hospitalized patients (48.3% vs. 61.5%; OR: 0.58: 95% CI 0.44-0.77). During the study period, 865 (1.21%) patients with asthma were being treated with biologics. Although these patients showed increased severity and more comorbidities at the ear, nose, and throat (ENT) level, their hospital admission rates due to COVID-19 were relatively low (0.23%). COVID-19 increased inpatient mortality in asthmatic patients (2.29% vs 0.54%; OR 2.29: 95% CI 4.35-6.66). Conclusion: Our results indicate that the number of COVID-19 cases in patients with asthma has been low, although higher than the observed in the general population. Patients with asthma and COVID-19 were older and were at increased risk due to comorbidity-related factors. ICS and biologics are generally safe and may be associated with a protective effect against severe COVID-19 infection.

scholarly journals ED visits and hospital admissions of foreigners for psychiatric disorders in Rome from 2007 to 2018

2019 ◽  
Vol 29 (Supplement_4) ◽  
Author(s):  
A Nardi ◽  
G Migliara ◽  
A Angelozzi ◽  
S Caminada ◽  
M Giffi ◽  
...  
Keyword(s):  
Mental Health ◽  
High Risk ◽  
Hospital Admission ◽  
Psychiatric Disorders ◽  
Service Use ◽  
Hospital Admissions ◽  
Mental Health Service Use ◽  
Related Factors ◽  
Ed Visits ◽  
And Migration

Abstract Background First generation immigrants are at high risk of psychiatric disorders (PD). Moreover, cultural and migration related factors can act as barriers in the access to care. The aim of this study was to analyze the emergency department (ED) visits and the subsequent admissions to Umberto I, a large teaching hospital in Rome, for PD from 2007 to 2018 and to highlight the differences between Italian citizens and foreigners. Methods Adult patients were divided in 11 Nationality Groups (NGs). Basing on ICD9 codes, PD were classified in 5 categories: psychotic, mood, anxiety, personality and substance abuse disorders. Descriptive statistics were conducted for gender, age, educational level and triage. Poisson regression models, adjusted for sociodemographic variables, were used to estimate incidence rate ratios (IRRs) of different NGs, both for visits and hospital admissions, for the five psychiatric categories and for PD as a whole. Results In the period of interest there were 11,965 ED visits for PD, of which 19.2% made by foreigners. Compared to Italians, all NGs showed higher percentages of ED visits for PDs, except for Southern Asian (SA) and East-Southern east Asian (ESA); SA and ESA, together with Other Africa population, showed also higher proportion of psychosis. Regarding admissions, ESA had the highest percentage overall, while more than half of foreigner nationality groups had higher percentages of admissions for psychosis than Italians. Poisson regressions showed that only EU citizens have greater risk of ED visit (IRR 1.69, IC95% 1.46-1.96) and of hospital admission for PD (IRR 1.23, IC95% 1.02-1.49) than Italians, while Romanians, SA and ESA have lower risk. Conclusions Different risk in ED visits for PDs among NGs can be due to heterogeneity in psychopathology, cultural factors, barriers, and migrant status. More studies are necessary to better understand the needs of foreigners and to enhance their mental health service use. Key messages The risk of ED visit and hospital admission for psychiatric disorders differ among foreign populations. Different study design are needed to understand which cultural and migration related factors influence the risks, in order to provide more tailored mental health services for high risk populations.

scholarly journals Use of the Airway Questionnaire 20 to Detect Changes in Quality of Life in Asthmatic Patients and its Association with the St George’s Respiratory Questionnaire and Clinical Parameters

2008 ◽  
Vol 15 (3) ◽  
pp. 133-137 ◽  
Author(s):  
Thida Win ◽  
Linda Pearce ◽  
James Nathan ◽  
Fay Cafferty ◽  
Clare Laroche
Keyword(s):  
Quality Of Life ◽  
Hospital Admission ◽  
Hospital Admissions ◽  
Peak Flow ◽  
Short Version ◽  
Flow Number ◽  
Asthmatic Patients ◽  
Bland Altman Method ◽  
St George's Respiratory Questionnaire

BACKGROUND AND OBJECTIVES: The usefulness of the Airway Questionnaire 20 (AQ20) – a short version of the St George’s Respiratory Questionnaire (SGRQ) – to evaluate quality of life (QOL) in asthmatic patients following a hospital admission was assessed.METHODS: At baseline and at six months following the index admission, 135 asthmatic patients were asked to complete the AQ20 and the SGRQ. The patient’s peak flow, number of subsequent asthma exacerbations and number of repeat hospital admissions were also recorded.RESULTS: The AQ20 scores ranged from 0 to 20, with a high score indicating poor QOL. The AQ20 had good coverage, with no obvious ceiling or floor effects. In multiple regression analysis, all three SGRQ components were important in predicting AQ20 scores (R2values were 61.9% and 73.1% for baseline and six-month scores, respectively). The AQ20 was closely correlated with the SGRQ, but not redundant when used together. Bias was low when the retest reliability of the AQ20 was evaluated using the Bland-Altman method, but variation was high (−0.64). Patients with subsequent exacerbations (n=52) had higher AQ20 scores at six-month follow-up (P=0.002). In logistic regression, the AQ20 score was closely associated with the incidence of exacerbations (OR 1.15, 95% CI 1.05 to 1.25), with a similar magnitude of association between the AQ20 and the SGRQ. The AQ20 score did not correlate with peak flow at baseline (r=−0.05; P=0.573) or at six months (r=−0.31; P=0.006), and was not responsive to changes in peak flow (r=−0.06; P=0.583).CONCLUSION: The AQ20 can be substituted for the more complicated SGRQ in the assessment of QOL in patients following a hospital admission for an asthma exacerbation.

scholarly journals Factors associated with hospital admission in patients reaching the emergency department with COPD exacerbation

2012 ◽  
Vol 7 ◽  
Author(s):  
Maria Teresa García-Sanz ◽  
Carlos Pol-Balado ◽  
Concepción Abellás ◽  
Juan Carlos Cánive-Gómez ◽  
Diana Antón-Sanmartin ◽  
...  
Keyword(s):  
Emergency Department ◽  
Multivariate Analysis ◽  
Observational Study ◽  
Hospital Admission ◽  
Prospective Observational Study ◽  
County Hospital ◽  
Copd Exacerbation ◽  
Related Factors ◽  
Factors Associated ◽  
Copd Exacerbations

Background: The aim of this study was to determine the frequency of COPD exacerbations in our Emergency Department, as well as the hospitalization-related factors. Methods: Prospective observational study conducted in the Emergency Department of Salnés County Hospital among patients admitted for COPD exacerbation. Admission predictors were determined by multivariate analysis. Results: There were 409 exacerbations in 239 patients (79% male, mean age 75). 57% of exacerbations required hospitalization. Hospitalization-related factors were impaired oxygenation (p<0.001), presence of neutrophilia (p<0.01) and prescription of antibiotics in the Emergency Department (p<0.05). Conclusions: COPD exacerbation accounts for over 1% of all visits to our Emergency Department. 57% of them required hospitalization. Impaired oxygenation, greater neutrophilia and prescription of antibiotics in the Emergency Department were associated with greater probability of admission.

Storage mite sensitivity and related factors in asthmatic patients

2015 ◽  
Vol 63 (4) ◽  
pp. 226-234
Author(s):  
Serdar AKPINAR ◽  
Sema CANBAKAN ◽  
Dilşad MUNGAN ◽  
Yılmaz BAŞER ◽  
Evrim Eylem AKPINAR
Keyword(s):  
Related Factors ◽  
Asthmatic Patients ◽  
Storage Mite

scholarly journals Drug-related factors affecting medication adherence among Egyptian asthma patients

2020 ◽  
Vol 14 (1) ◽  
Author(s):  
Abdellah H K Ali ◽  
Esraa Ameen ◽  
Kamal Atta ◽  
Khaled Fawzy Alkhayat
Keyword(s):  
Medication Adherence ◽  
Demographic Data ◽  
Strong Relationship ◽  
University Hospital ◽  
Onset Of Action ◽  
Related Factors ◽  
Factors Affecting ◽  
Asthmatic Patients ◽  
Asthma Patients ◽  
High Level

Abstract Background The aim of this study is to evaluate adherence to inhaler therapy in asthmatic patients and examine drug-related factors affecting medication adherence among Egyptian asthma patients. The study was carried out among 110 clinically diagnosed asthma patients attending at a university hospital, Sohag, Egypt. Inhaler criteria and adherence were evaluated by a standardized tool “Morisky Medication Adherence Scale (MMAS), 2008.” Results The study revealed that out of 110 patients, 42.2% had a high level, 22.9% had medium level, and 34.9% had a low level of medication adherence. There was no relationship between demographic data and medication adherence in asthmatic patients. However, good adherence was frequently encountered among asthmatic patients who used inhaler twice daily, who used drugs its onset of action 5-20 min, who used aerolizer and turbo haler devices, and who used budesonide and budesonide/formoterol. Conclusions Poor adherence to inhaler therapy is high in patients with bronchial asthma attending Sohag University Hospital in Upper Egypt. There was a strong relationship between inhaled drug criteria and degree of adherence in asthmatic patients.

scholarly journals The Impact of COVID-19 on Patients with Asthma

2020 ◽  
pp. 2003142 ◽  
Author(s):  
José Luis Izquierdo ◽  
Carlos Almonacid ◽  
Yolanda González ◽  
Carlos Del Rio-Bermúdez ◽  
Julio Ancochea ◽  
...  
Keyword(s):  
Disease Burden ◽  
Inhaled Corticosteroids ◽  
Big Data Analytics ◽  
Related Factors ◽  
Asthmatic Patients ◽  
Hospitalised Patients ◽  
Increased Risk ◽  
Predominantly Female ◽  
The Impact ◽  
Diabetes And Obesity

BackgroundAn association between the severity of COVID-19 and the presence of certain chronic conditions has been suggested. However, unlike influenza and other viruses, the disease burden in patients with asthma has been less evident.ObjectiveTo understand the impact of COVID-19 in patients with asthma.MethodsUsing big data analytics and artificial intelligence through the SAVANA Manager® clinical platform, we analysed clinical data from patients with asthma from January 1st to May 10th, 2020.ResultsOut of 71 182 patients with asthma, 1006 (1.41%) suffered from COVID-19. Compared to asthmatic individuals without COVID-19, patients with asthma and COVID-19 were significantly older (55 versus 42 years), predominantly female (66% versus 59%), smoked more frequently, and had higher prevalence of hypertension, dyslipidemias, diabetes, and obesity. Allergy-related factors such as rhinitis and eczema were less common in asthmatic patients with COVID-19 (p<.001). Higher prevalence of these comorbidities was also observed in patients with COVID-19 who required hospital admission. The use of inhaled corticosteroids (ICS) was lower in patients who required hospitalisation due to COVID-19, as compared to non-hospitalised patients (48.3% versus 61.5%; OR: 0.58: 95% CI 0.44–0.77). Although patients treated with biologics (n=865; 1.21%) showed increased severity and more comorbidities at the ENT level, COVID-19-related hospitalisations in these patients were relatively low (0.23%).ConclusionPatients with asthma and COVID-19 were older and at increased risk due to comorbidity-related factors. ICS and biologics are generally safe and may be associated with a protective effect against severe COVID-19 infection.

Sequential degranulation of eosinophils induced by antigen or autocoids in allergic humans

1986 ◽  
Vol 44 ◽  
pp. 354-355
Author(s):  
Kate W. Sjoerdsma ◽  
W. James Metzger
Keyword(s):  
Allergic Rhinitis ◽  
Bronchoalveolar Lavage ◽  
Allergic Asthma ◽  
Skin Test ◽  
Positive Skin Test ◽  
Positive Skin ◽  
Human Eosinophil ◽  
Asthmatic Patients ◽  
Allergic Asthmatic ◽  
History Of

Eosinophils are important to the pathogenesis of allergic asthma, and are increased in bronchoalveolar lavage within four hours after bronchoprovocation of allergic asthmatic patients, and remain significantly increased up to 24 hours later. While the components of human eosinophil granules have been recently isolated and purified, the mechanisms of degranulation have yet to be elucidated.We obtained blood from two volunteers who had a history of allergic rhinitis and asthma and a positive skin test (5x5mm wheal) to Alternaria and Ragweed. Eosinophils were obtained using a modification of the method described by Roberts and Gallin.

Practical Importance of Spatial Resolution and Analytical Sensitivity in AEM X-ray Microanalysis

1990 ◽  
Vol 48 (2) ◽  
pp. 432-433
Author(s):  
J. Zhang ◽  
D.B. Williams ◽  
J.I. Goldstein
Keyword(s):  
Spatial Resolution ◽  
Practical Importance ◽  
Beam Current ◽  
Specimen Thickness ◽  
Analytical Sensitivity ◽  
Related Factors ◽  
X Ray ◽  
Probe Size ◽  
Excitation Volume ◽  
Two Parameters

Analytical sensitivity and spatial resolution are important and closely related factors in x-ray microanalysis using the AEM. Analytical sensitivity is the ability to distinguish, for a given element under given conditions, between two concentrations that are nearly equal. The analytical sensitivity is directly related to the number of x-ray counts collected and, therefore, to the probe current, specimen thickness and counting time. The spatial resolution in AEM analysis is determined by the probe size and beam broadening in the specimen. A finer probe and a thinner specimen give a higher spatial resolution. However, the resulting lower beam current and smaller X-ray excitation volume degrade analytical sensitivity. A compromise must be made between high spatial resolution and an acceptable analytical sensitivity. In this paper, we show the necessity of evaluating these two parameters in order to determine the low temperature Fe-Ni phase diagram.A Phillips EM400T AEM with an EDAX/TN2000 EDS/MCA system and a VG HB501 FEG STEM with a LINK AN10 EDS/MCA system were used.

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