EFFECT OF ADDING COMMON NETTLE EXTRACTS TO DRINKING WATER ON THE LIPID PEROXIDATION, ANTIOXIDANT ENZYMES ACTIVITY AND GLUTATHIONE LEVEL IN EGGS OF LAYING HENS EXPOSED TO ELEVATED AIR TEMPERATURE

Author(s):  
Renata Muchacka ◽  
◽  
E. Sosnówka-Czajka ◽  
I. Skomorucha ◽  
Edyta Kapusta ◽  
...  
2012 ◽  
Vol 134 (3-4) ◽  
pp. 184-190 ◽  
Author(s):  
Agnieszka Partyka ◽  
Ewa Łukaszewicz ◽  
Wojciech Niżański

Author(s):  
O. V. Lototska

Introduction One of the reasons for the lack of quality drinking water is the poor quality of natural water, which is constantly polluted by waste water from industrial and municipal enterprises, surface runoff from the fields and territories of settlements with which it enters a large amount of toxic substances. Among them, surface-active substances such as potassium and sodium stearate are not the last.The aim of the study to determine the specifics of lipid peroxidation and the state of the antioxidant protection under the influence of potassium and sodium stearates on the body of the experimental rats when they enter with drinking water.Research Methods. White rats were divided into 7 groups, which consumed water with stearates in quantities equal to the maximum non-active dose of the substance (MND), 1/2 MND and 1/4 MND for 25 days. The content of TBC-active lipid peroxidation products, diene conjugates and the activity of superoxide dismutase and catalase in liver homogenate were determined.Results and Discussion. In the homogenate of the liver of animals of all groups, there was a significant increase in the level of diene conjugates and TBK-active products in proportion to the concentration of the substance. It was also found that in animals that consumed water with different concentrations of potassium stearate, inhibition of antioxidant enzymes was observed. Consumption of water with different concentrations of sodium stearate caused the activation of these enzymes.Conclusions. Prolonged use by test animals of aqueous solution with  concentrations of potassium and sodium stearate in MND and 1/2 MND negatively affects the state of hepatocyte cell membranes due to the activation of the lipid peroxidation processes, namely TBK-active products and diene conjugates, the amount of which depended on the concentration of stearates in drinking water. The use of drinking water by test animals with maintenance of potassium and sodium stearates at various doses caused changes in the content of antioxidant enzymes: water with potassium stearate inhibits the activity of these indicators, and causes sodium activation with sodium stearate.


2013 ◽  
Vol 12 (1) ◽  
pp. 315 ◽  
Author(s):  
Camila Fabbri ◽  
Rita de Cássia Mascarenhas-Netto ◽  
Pritesh Lalwani ◽  
Gisely C Melo ◽  
Belisa ML Magalhães ◽  
...  

2004 ◽  
Vol 42 (3) ◽  
pp. 429-438 ◽  
Author(s):  
M Jurczuk ◽  
M M. Brzóska ◽  
J Moniuszko-Jakoniuk ◽  
M Gałażyn-Sidorczuk ◽  
E Kulikowska-Karpińska

2018 ◽  
Vol 111 (1) ◽  
pp. 169 ◽  
Author(s):  
Natalia KAZNINA ◽  
Julia BATOVA ◽  
Natalia REPKINA ◽  
Galina LAIDINEN ◽  
Alexandr TITOV

<p>The cadmium effect (100 μM) on the barley (<em>Hordeum vulgare</em> L.) growth, the content of <em>HvCu/ZnSOD</em>, <em>HvCAT2</em> and <em>HvPRX07</em> transcripts and the antioxidant enzymes activity (SOD, CAT and PRX) in roots and leaves of seedlings under optimal (22 °C) and low (4 °C) temperatures were studied. Exposure to cadmium at 22 °C did not inhibit the plants’ growth. In this case, the rate of the oxidative processes in the cells remained at the control level. This was achieved by a corresponding increase of the gene<em> </em>transcripts and the antioxidant enzymes activity in roots and leaves. In contrast, exposure to cadmium at 4 °C inhibited the seedlings’ growth despite of the lower metal content in the plants. Moreover the rate of lipid peroxidation in the roots and leaves increased significantly. It is assumed that this effect was connected with the accumulation of excess amounts of hydrogen peroxide due to a misbalance between its generation and neutralization. This assumption is confirmed by the obtained data, according to which the level of <em>HvCu/ZnSOD </em>expression and the total activity of SOD increased significantly under exposure to cadmium at 4 °C, although <em>HvCAT2</em> and <em>HvPRX07</em> transcripts and CAT and PXR activity did not rise.</p>


2020 ◽  
Vol 13 (1) ◽  
pp. 220-230
Author(s):  
Simon Gabriel Mafulul ◽  
Enoch Banbilbwa Joel ◽  
Chukwudi Acha Orji ◽  
Comfort Sokomba Edah ◽  
Larry Auta Barde ◽  
...  

The present study determined the effect of pre-supplementation with manganese (Mn) and selenium (Se) on biomarkers of oxidative stress in the liver and kidneys of rats exposed to a mild dose of cadmium. Sixteen Male Wistar strain rats (180-200 g b. wt) were divided into four groups (control, Cd alone, Mn + Se + Cd and Mn + Se). The rats used as the control received a normal rat diet and tap water throughout the study while the Cd alone rats received a normal rat diet and then exposed to a single daily oral dose of cadmium (3 mg CdCl2/kg) in drinking water for three days. Mn + Se + Cd rats were pretreated with Mn (3 mg MnCl2/kg/day) and Se (3mg SeO2/kg/day) for seven days and thereafter received a single daily oral dose of cadmium (3 mg CdCl2/kg) in drinking water for three days while Mn + Se rats were exposed to only Mn (3 mg MnCl2/kg/day) and Se (3mg SeO2/kg/day) for seven days. At the end of the experiment tissue cadmium concentration, membrane lipid peroxidation, glutathione content, and activities of antioxidant enzymes catalase, superoxide dismutase, and glutathione peroxidase were determined in the liver and kidney samples. The results showed that pretreatment with Mn and Se effectively countered Cd-induced cadmium accumulation, membrane lipid peroxidation, depletion of the non-enzymic antioxidant, glutathione, and induction of the antioxidant enzymes catalase, superoxide dismutase and glutathione peroxidase in the liver and kidney. It can be concluded that pre-supplementation with Mn and Se significantly reversed Cd-induced deleterious alterations in the liver and kidney tissue of the rats.


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