scholarly journals Evaluation of Antimicrobial Effects of Four Selected Marine Macroalgae from Iskenderun Bay

2021 ◽  
Vol 9 (12) ◽  
pp. 2253-2259
Author(s):  
Selin Sayın ◽  
Betül Aydın ◽  
Burcu Ak Çimen ◽  
Leyla Açık
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activities ◽  
Marine Macroalgae ◽  
Pathogenic Microorganisms ◽  
Proteus Vulgaris ◽  
Bacterial Strains ◽  
C Elegans ◽  
Iskenderun Bay ◽  
Mic Value

In the present study, the seaweeds belong to Phaeophyaceae (Cystoseira elegans Sauvageau 1912, Cystoseira amentacea (C.Agardh) Bory 1832, Padina crassa Yamada 1931) and Florideophyceae (Corallina elongata J.Ellis & Solander 1786) collected from nearby Iskenderun-Turkey of Mediterranean Sea were detected for their antimicrobial activities against seven bacterial strains (Escherichia coli ATCC 35218, Bacillus cereus NRRL B-371, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 13883, Salmonella typhimurium ATCC 14028, Proteus vulgaris RSKK 96029). The antimicrobial activities were expressed as minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs). According to the results obtained from MICs and MBCs values of the extracts on pathogenic microorganisms were between 0.78 to 50 mg/mL. The lowest MICs and MBCs values were recorded for C. elegans extract against B. cereus with a MIC value of 0.78 mg/mL. These results suggest that secondary metabolites of brown and red algae are important sources that could be used as broad spectrum of biological and pharmaceutical activities.

scholarly journals Antimicrobial Activities of Some Marine Macroalgae Species from Iskenderun Bay

2021 ◽  
Vol 9 (4) ◽  
pp. 792-796
Author(s):  
Selin Sayın
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activities ◽  
Marine Macroalgae ◽  
Pathogenic Microorganisms ◽  
Proteus Vulgaris ◽  
Iskenderun Bay ◽  
Halopteris Scoparia ◽  
Bacterial Concentrations

In the present study, the seaweeds belong to Phaeophyaceae (Halopteris scoparia (Linnaeus) Sauvageau 1904, Cystoseria mediterranea Sauvageau 1912), Rhodophaceae (Liagora viscida (Forsskål) C.Agardh 1822, Laurencia nidifica J.Agardh 1852) and Chlorophyceae (Enteromorpha multiramosa Bliding, nom. inval. 1960) collected from nearby Iskenderun-Turkey of Mediterranean Sea were detected for their antimicrobial activities against seven bacterial (Escherichia coli ATCC 35218, Bacillus cereus NRRL B-371, Staphylococcus aureus ATCC 25923, Pseudomonas aeruginosa ATCC 27853, Klebsiella pneumoniae ATCC 13883, Salmonella typhimurium ATCC 14028, Proteus vulgaris RSKK 96029) and three fungal strains (Candida albicans ATCC 10231, C. krusei ATCC 6258, C. tropicalis Y-12968). The antimicrobial activities were expressed as minimum inhibitory concentrations (MICs), minimum bacterial concentrations (MBCs) and minimum fungicidal concentrations (MFCs) were determined. According to the results obtained from MIC values of the extracts on pathogenic microorganisms were between 50 and 50 and

scholarly journals ANTIBACTERIAL PHOTODYNAMIC THERAPEUTIC STUDIES OF METALLATED PORPHYRIN AGAINST CHRONIC WOUND COLONISING BACTERIAL ISOLATES

2021 ◽  
Vol 46 (2) ◽  
Author(s):  
O. B Daramola ◽  
A. A Olajide ◽  
N Torimiro ◽  
R. C George
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Chronic Wound ◽  
Antimicrobial Activities ◽  
Diffusion Method ◽  
In Vitro Toxicity ◽  
Resistant Bacteria ◽  
Drug Resistant ◽  
Bacterial Strains

Wound infections have become life threatening as a result of treatment failures caused by multi-drug resistant pathogens. The search for newer compounds potent against antibiotic resistant bacteria associated with wounds is crucial. Hence this study investigated the application of antibacterial photodynamic therapy using meso tetra-(4-phenyl) porphyrin (TPP), metallated with zinc, tin and silver (ZnTPP, SnTPP and AgTPP), meso tetra-(4-sulphonatephenyl) porphyrin (TPPS) and the corresponding metallo meso tetra-(4-sulphonatephenyl) porphyrin (MTPPS) as photosensitizers. The in-vitro toxicity and photo-toxicity properties on four chronic wound colonizing multi-drug resistant bacterial strains: Staphylococcus aureus, Klebsiella sp., Proteus sp., and Escherichia coli were assessed using agar well diffusion method. Photo-toxicity of the compounds was investigated using 100 Watt tungsten lamp. Inhibitory activity of porphyrins tested against these bacterial strains showed Staphylococcus aureus to have both lowest (11±0.0 mm) and highest (33±1.1 mm) susceptibility to SnTPPS and ZnTPPS respectively. The sequence of data also showed appreciable improvement in the antimicrobial activities of five metalloporphyrins (SnTPP, AgTPP, ZnTPPS, SnTPPS and AgTPPS) exposed to light rays than when tested against bacterial strains in dark condition. ZnTPPS exhibited the best activity with improved photo-toxic activities against all bacterial strains (Staphylococcus aureus 33±1.1 mm, Klebsiella sp. 32±0.7 mm, Proteus sp. 28±0.7 mm and Escherichia coli 30±1.4 mm) examined in this study.

scholarly journals Antibacterial effect of Czech and Mānuka honey on selected mastitis pathogens

2018 ◽  
Vol 87 (4) ◽  
pp. 387-393
Author(s):  
Marcela Klimešová ◽  
Irena Němečková ◽  
Eva Vondrušková ◽  
Ludmila Nejeschlebová
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Effect ◽  
Bacterial Species ◽  
Inhibitory Effect ◽  
Pathogenic Microorganisms ◽  
Bacterial Strains ◽  
Manuka Honey ◽  
Streptococcus Uberis ◽  
Mastitis Pathogens

The work is focused on the antibacterial effect of four types of blossom honey, one honeydew and two Mānuka honey (MAN100+ and MAN400+) on selected pathogenic microorganisms isolated from cow’s milk (Staphylococcus aureus 51 and S. aureus 428), sheep’s milk (S. aureus 627), and from the Czech Collection of Microorganisms (Streptococcus uberis CCM 4617, Streptococcus agalactiae CCM 6187, Enterococcus faecalis CCM 4224 and Escherichia coli CCM 4787). The concentrations of honey samples were 20% and 30%. The obtained results showed a 100% inhibitory effect of MAN400+ on all tested bacterial strains even at a concentration of 20% and also a comparable inhibitory effect of Mānuka honey with Czech honeydew. The results indicate that honey had an inhibitory effect against the tested bacterial species which may cause mastitis.

scholarly journals Design, Synthesis and Study of Antibacterial and Antitubercular Activity of Quinoline Hydrazone Hybrids

2020 ◽  
Vol 26 (1) ◽  
pp. 137-147
Author(s):  
Shruthi T G ◽  
Sangeetha Subramanian ◽  
Sumesh Eswaran
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Bacterial Resistance ◽  
Biological Activities ◽  
Antitubercular Activity ◽  
Bacterial Strains ◽  
Acinetobacter Baumanii ◽  
Design Synthesis ◽  
Mic Value

AbstractEmerging bacterial resistance is causing widespread problems for the treatment of various infections. Therefore, the search for antimicrobials is a never-ending task. Hydrazones and quinolines possess a wide variety of biological activities. Herewith, eleven quinoline hydrazone derivatives have been designed, synthesized, characterized and evaluated for their antibacterial activity and antitubercular potential against Mtb WT H37Rv. Compounds QH-02, QH-04 and QH-05 were found to be promising compounds with an MIC value of 4 μg/mL against Mtb WT H37Rv. Compounds QH-02, QH-04, QH-05, and QH-11 were also found to be active against bacterial strains including Acinetobacter baumanii, Escherichia coli and Staphylococcus aureus. Further, we have carried out experiments to confirm the cytotoxicity of the active compounds and found them to be non-toxic.

scholarly journals Synthesis and Antimicrobial Activities of some Quaternary Morpholinium Chlorides

2010 ◽  
Vol 59 (1) ◽  
pp. 49-53 ◽  
Author(s):  
BOGUMIŁ BRYCKI ◽  
ZOFIA DEGA-SZAFRAN ◽  
ILONA MIRSKA
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antimicrobial Activity ◽  
Candida Albicans ◽  
Nitrogen Atom ◽  
Alkyl Group ◽  
Antimicrobial Activities ◽  
Proteus Vulgaris

The synthesis and antimicrobial activity of 31 morpholinium chlorides, divided into five series depending on the substituents attached to the nitrogen atom, N-carboxyalkyl-morpholinium chlorides (1a-e), N-carbalkoxymethyl-N-methyl-morpholinium chlorides (2a-f), N-carbethoxymethyl-N-alkyl-morpholinium chlorides (3a-g), N-carbalkoxymethyl-N-dodecyl-morpholinium chlorides (4a-f) and N-carboxymethyl-N-alkyl-morpholinium chlorides (5a-g) is reported. The compounds investigated were tested for antimicrobial activity against Staphylococcus aureus, Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa, Candida albicans and Trichophyton menthagrophytes. The most active are compounds with a long N-alkyl group and with the substituent CH2COOC(n)H(2n-1) (n = 8-16).

scholarly journals Syntheses, Characterization, and Antimicrobial Screening of N-(benzothiazol-2-yl)benzenesulphonamide and its Cu(I), Ni(II), Mn(II), Co(II), and Zn(II) Complexes

2012 ◽  
Vol 9 (4) ◽  
pp. 2354-2370 ◽  
Author(s):  
N. L. Obasi ◽  
Okoye C. O. Benedict ◽  
P. O. Ukoha ◽  
A. O. Anaga
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Metal Complexes ◽  
Inhibition Zone ◽  
Antimicrobial Activities ◽  
Candida Krusei ◽  
Diffusion Method ◽  
Bacterial Strains

N-(benzothiazol-2-yl)benzenesulphonamide (BS2ABT) was synthesized by the condensation (by refluxing) of 2-aminobenzothiazole and benzenesulphonylchloride in acetone at 140ºC. The resulting crude precipitates were recrystallized from dimethylformamide (DMF). Five metal complexes of copper(I), nickel(II), manganese(II), cobalt(II) and zinc(II) of the ligands were synthesized. The compounds were characterized using magnetic susceptibility measurements, UV/VIS spectrophotometry, infra red, proton and13C nmr spectroscopies. The antimicrobial tests of the ligands and its metal complexes were carried out on both multi-resistant bacterial strains isolated under clinical conditions and cultured species using agar-well diffusion method. The multi-resistant bacterial strains used wereEscherichia coli, Proteusspecies,Pseudomonas aeroginosa and Staphylococcus aureuswhich were isolated from dogs. The culture species werePseudomonas aeruginosa(ATCC 27853),Escherichia Coli(ATCC 25922)Staphylococcus aureus(ATCC 25923), and the fungi,Candida krusei(ATCC 6258) andCandida albicans(ATCC 90028). The tests were bothin vitroandin vivo. Thus the Inhibition Zone Diameter (IZD), the Minimum Inhibitory Concentration (MIC), and the Lethal and Effective Concentrations (LC50and EC50) were determined. The antimicrobial activities of the compounds were compared with those of Ciprofloxacin and trimethoprim-sulphamethoxazole as antibacterial agents and Fluconazole as an antifungal drug. All the compounds showed varying activities against the cultured typed bacteria and fungi used. However, they were less active than the standard drugs used except Fluconazole which did not show any activity againstCandida krusei(ATCC 6258) but most of the compounds synthesized were very active against it. The Lethal Concentration (LC50) ranged from 26.25±4.9-1833.88±186.92 ppm. These are within the permissible concentrations.

scholarly journals Antimicrobial Activity of Copper(II) and Cobalt(II) Complexes of Citral-Valine Derived Schiff Base

2019 ◽  
Vol 32 (1) ◽  
pp. 192-194
Author(s):  
S. Sudha Kumari
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Antibacterial Activity ◽  
Schiff Base ◽  
Candida Albicans ◽  
Schiff Base Ligand ◽  
Antimicrobial Activities ◽  
Bacterial Strains ◽  
Gram Negative

In present work, the screening of antimicrobial activities of copper(II) and cobalt(II) complexes with Schiff base ligand derived from the condensation of citral with valine (amino acid) was carried out on agar plates are reported. The antibacterial activity of Schiff base and its copper(II) and cobalt(II) complexes were evaluated against two bacterial strains Staphylococcus aureus (Gram-positive), Escherichia coli (Gram-negative) and fungus Candida albicans. The results revealed that the Schiff base ligand exhibited the poor antimicrobial activity against Escherichia coli and Candida albicans except for Staphylococcus aureus. Generally, Gram-negative bacteria shows rigid outer membrane, well enough to defend against the drug but Schiff base (citral with valine derived) impregnated cobalt(II) complex seem to be more active against Escherichia coli organisms in comparison to copper(II) complex, which exhibits higher activity than uncomplexed ligand. The antimicrobial results revealed that cobalt(II) and copper(II) complexes have a considerable antibacterial activity than antifungal activity and suggest their potential application as antibacterial agents.

Antimicrobial Activity of Compounds from Artemisia campestris

1983 ◽  
Vol 46 (3) ◽  
pp. 185-187 ◽  
Author(s):  
SALEM M. THARIB ◽  
SAID O. GNAN ◽  
G. BRYAN A. VEITCH
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Antimicrobial Activity ◽  
Antimicrobial Activities ◽  
Proteus Vulgaris ◽  
Agar Diffusion ◽  
Diffusion Technique ◽  
Artemisia Campestris ◽  
Pseudomonas Pyocyanea

The antimicrobial activities of several compounds isolated from Artemisia campestris were studied using an agar diffusion technique. At a concentration of 125 μg/ml, six of the extracted compounds inhibited growth of Staphylococcus aureus, three of the compounds inhibited Escherichia coli and two inhibited growth of Proteus vulgaris. Pseudomonas pyocyanea was resistant to all extracted compounds.

scholarly journals Synthesis and Antibacterial Activity of New Spiro[thiadiazoline-(pyrazolo[3,4-d]pyrimidine)] Derivatives

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Mohammed El Fal ◽  
Youssef Ramli ◽  
Abdelfettah Zerzouf ◽  
Ahmed Talbaoui ◽  
Youssef Bakri ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Spectroscopic Data ◽  
Heterocyclic Compounds ◽  
Dipolar Cycloaddition ◽  
Bacterial Strains ◽  
Pyrimidine Derivatives ◽  
H Nmr ◽  
Biological Interest ◽  
Mic Value

New heterocyclic compounds spiroderivatives of allopurinol of biological interest were prepared from allopurinol via thionation and 1,3-dipolar cycloaddition and were produced in high to excellent yields. These compounds were characterized on the basis of spectral and spectroscopic data (1H NMR,13C, IR, and MS). The antibacterial activity of the synthesized products was studied using bacterial strains:Staphylococcus aureus,Enterococcus faecalis,Escherichia coli, andPseudomonas aeruginosa. Compounds having an ethyl group showed the best activity with MIC value of 31.25 µg/mL againstStaphylococcus aureusandStreptococcus fasciens.

scholarly journals FLORAL EXTRACT OF Tibouchina granulosa (DESR.) COGN. PHYTOCHEMISTRY PROSPECTION, AND ANTIBACTERIAL ACTIVITY

2021 ◽  
Vol 5 (1) ◽  
pp. 1-9
Author(s):  
Antonio Carlos Pereira de Menezes Filho ◽  
Matheus Vinícius Abadia Ventura ◽  
Carlos Frederico de Souza Castro
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Antibacterial Activity ◽  
Enterococcus Faecalis ◽  
Floral Organ ◽  
Salt Formation ◽  
Bacterial Strains ◽  
Positive Results

Tibouchina granulosa is a species that blooms annually in several regions of Brazil. This species is still little explored in terms of phytocompounds in all organs of this plant, especially the floral organ. Flowers of T. granulosa were collected in the municipality of Rio Verde, Goiás, Brazil, in 2021. The hydroethanolic floral extract was prepared by maceration and qualitative phytochemical (colorimetric reactions and salt formation) and antibacterial analyzes performed and the results expressed in millimeters of inhibition at different concentrations in mg mL-1. Several phytochemical classes were observed with positive results, especially for alkaloids, phenolics, oxylates, saponins, carbohydrates and tannins. As for the bacterial assay, potential antibacterial activity was observed for all bacterial strains tested, except for Salmonella serovar Thyphymurium and serovar Enteritidis. Expressive inhibitions were observed for Enterococcus faecalis > Pseudomonas aeruginosa > Staphylococcus aureus and Escherichia coli at the highest concentrations between 100-50 mg mL-1. The floral extract of Tibouchina granulosa showed phytotherapeutic potential with the presence of several phytochemical groups and expressive antibacterial activity.

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