INVESTIGATION OF SURFACE FUNCTIONALIZATION AND COATINGS FOR BIOMEDICAL APPLICATIONS BY ZETA POTENTIAL AND ADSORPTION MEASUREMENTS ON SOLID SURFACES

The physicochemical properties of the nanoparticle surface determine the performance of nanocomposites in biomedical applications such as their biodistribution and pharmacokinetics. The physicochemical properties of chitosan, such as apparent charge density and solubility, are pH dependent. Similarly, Fe3O4 nanoparticles are susceptible to variations in their physicochemical properties due to changes in pH. In this work, we evaluated the physicochemical properties of chitosan–magnetite nanocomposites that were suspended at pH 7.0, 9.0, and 11.0 to determinate the effect on particle size, zeta potential, and mass percentage of the polymeric coating, in addition to the crystalline phase and magnetic properties of magnetite phase. X-ray diffraction results exposed that the present phase was magnetite with no other phases present and that the crystallite size was between 10.8 and 14.1 nm. Fourier transform infrared verified the chitosan functional groups in treated samples while the percentage of mass determined by TGA found to be nearly 9%. Scanning electron microscopy micrographs corroborated the spherical shape of the bare and chitosan-coated nanoparticles. Dynamic light scattering results showed that chitosan coating modifies the zeta potential, going from a potential of −11.8 mV for bare particles to −3.0 mV (pH 11). Besides, vibrating sample magnetometer measurements showed that coercivity remained very low, which is desirable in biomedical applications.

Superparamagnetic Twist-Type Actuators with Shape-Independent Magnetic Properties and Surface Functionalization for Advanced Biomedical Applications

Advanced Functional Materials ◽

10.1002/adfm.201400596 ◽

2014 ◽

Vol 24 (33) ◽

pp. 5269-5276 ◽

Cited By ~ 49

Author(s):

Christian Peters ◽

Olgaç Ergeneman ◽

Pedro D. Wendel García ◽

Michelle Müller ◽

Salvador Pané ◽

...

Keyword(s):

Magnetic Properties ◽

Surface Functionalization ◽

Biomedical Applications

Biomedical Applications: Surface Functionalization of Gold Nanoparticles with Red Blood Cell Membranes (Adv. Mater. 26/2013)

Advanced Materials ◽

10.1002/adma.201370169 ◽

2013 ◽

Vol 25 (26) ◽

pp. 3616-3616 ◽

Cited By ~ 2

Author(s):

Weiwei Gao ◽

Che-Ming J. Hu ◽

Ronnie H. Fang ◽

Brian T. Luk ◽

Jing Su ◽

...

Keyword(s):

Gold Nanoparticles ◽

Blood Cell ◽

Surface Functionalization ◽

Red Blood Cell ◽

Biomedical Applications ◽

Cell Membranes ◽

Red Blood Cell Membranes

Facile Hydrothermal Synthesis and Surface Functionalization of Polyethyleneimine-Coated Iron Oxide Nanoparticles for Biomedical Applications

ACS Applied Materials & Interfaces ◽

10.1021/am302883m ◽

2013 ◽

Vol 5 (5) ◽

pp. 1722-1731 ◽

Cited By ~ 185

Author(s):

Hongdong Cai ◽

Xiao An ◽

Jun Cui ◽

Jingchao Li ◽

Shihui Wen ◽

...

Keyword(s):

Iron Oxide ◽

Hydrothermal Synthesis ◽

Iron Oxide Nanoparticles ◽

Surface Functionalization ◽

Biomedical Applications ◽

Oxide Nanoparticles

Adsorption Processes at Solid Surfaces-Studied by Electrokinetic Investigations

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.314.19 ◽

2006 ◽

Vol 314 ◽

pp. 19-24 ◽

Cited By ~ 4

Author(s):

Cornelia Bellmann ◽

Anja Caspari

Keyword(s):

Zeta Potential ◽

Surface Chemistry ◽

Solid Surface ◽

Adsorption Process ◽

Ph Value ◽

Streaming Potential ◽

Solid Surfaces ◽

Multicomponent Mixtures ◽

Adsorption Processes ◽

Different Shapes

The process of electrophoretic deposition depends strongly on the electrokinetic properties and with it the surface properties of the material that will be processed. Different additives, conditioners but also the suspending liquid influence the surface of the applied material by adsorption. Electrokinetic investigations reflect changes in properties at the outermost solid surface very sensitive. Streaming potential measurements are especially suited for studying such changes of surface chemistry at solids with different shapes. Two approaches are applicable: 1. The adsorption process was done before measuring. The result of this process should be shown. In this case it will be interesting to see differences in the functionality of the solid surface. The zeta potential will be measured versus different pH value. 2. The adsorption process will be studied directly. The zeta potential will be determined versus the concentration of the adsorptive. The second approach can be used for investigation of adsorption of multicomponent mixtures. Competing adsorption processes are detectable.

Physicochemical properties and in vitro stability studies of green synthesized gold nanoparticles using pelargonium sidoides

Nigerian Journal of Technology ◽

10.4314/njt.v39i3.18 ◽

2020 ◽

Vol 39 (3) ◽

Author(s):

U.M. Badeggi ◽

B.A. Lawal ◽

A.O. Akinfenwa ◽

Y.O. Ayipo ◽

Y. Azeh ◽

...

Keyword(s):

Gold Nanoparticles ◽

Zeta Potential ◽

Biomedical Applications ◽

Capping Agent ◽

Stability Studies ◽

Hybrid Particles ◽

Pelargonium Sidoides ◽

In Vitro Stability ◽

532 Nm

In the present study, Pelargonium sidoides (PS) extract was used in the green synthesis of AuNPs that was characterized by UV-Vis, TEM, SAED, EDS, XRD, FTIR, and DLS. UV-Vis showed a surface plasmon resonance (SPR) at λmax of 532 nm while TEM shows that the particles are predominantly spherical and monodispersed. DLS measurement indicated the particle size and the zeta potential to be 27.20 nm and -24.0 mV respectively. The in vitro stability of the hybrid particles in different solutions and buffers (pH 7 and 9) confirmed that the particles are stable over a given period. The method employed is simple, environmentally friendly, and inexpensive. Our studies suggest that the Pelargonium sidoides-gold nanoparticles (PS-AuNPs) may be safely used in biomedical applications such as drug delivery. Keywords: Pelargonium sidoides; biosynthesis; biomedicals; capping agent; zeta potential

Nanogels obtained by gamma radiation induced polymerization

Polimery ◽

10.14314/polimery.2021.9.1 ◽

2021 ◽

Vol 66 (9) ◽

pp. 451-458

Author(s):

Nur Fathin Amirah Shafie ◽

Mohd Yusof Hamzah ◽

Roshafima Rasit Ali

Keyword(s):

Light Scattering ◽

Dynamic Light Scattering ◽

Zeta Potential ◽

Ethylene Glycol ◽

Gamma Radiation ◽

Biomedical Applications ◽

Poly Ethylene Glycol ◽

Glycol Diacrylate ◽

Radiation Induced ◽

Poly Ethylene

The influence of 2-(dimethylamino)ethyl methacrylate (DMAEMA) concentration on the temperature sensitivity of nanogels based on N-isopropylacrylamide (NIPAAM), poly(vinylpyrrolidone) (PVP), poly(ethylene glycol) diacrylate (PEGDA) by gamma radiation induced polymerization was investigated. Dynamic light scattering (DLS) and zeta potential measurements were used to characterize the nanogels. Temperature has been found to cause the nanogel particles to swell and shirnkage, allowing controlled dosing of the drug contained in capsules. The developed nanogels are promising materials with great potential for biomedical applications.

Current advances in bio-fabricated quantum dots emphasising the study of mechanisms to diversify their catalytic and biomedical applications

Dalton Transactions ◽

10.1039/d1dt01529j ◽

2021 ◽

Author(s):

Reddhy Mahle ◽

Partha Kumbhakar ◽

Divya Nayar ◽

Tharangattu N. Narayanan ◽

Kishor Kumar Sadasivuni ◽

...

Keyword(s):

Quantum Dots ◽

Surface Functionalization ◽

Biomedical Applications ◽

Recent Progress

Recent progress in the bio-mediated preparation of quantum dots as a greener and efficacious approach towards their surface functionalization in light of their varied applications is summarised.