scholarly journals Preparation and SPF Evaluation of Sunscreen Cream Containing Titanium Dioxide

2019 ◽  
Vol 35 (1) ◽  
Author(s):  
Tran Thi Hai Yen ◽  
Le Thu Huong ◽  
Nguyen Thi Thanh Duyen ◽  
Vu Thi Thu Giang
Keyword(s):  
Titanium Dioxide ◽  
Physical Stability ◽  
Biological Evaluation ◽  
Protection Factor ◽  
Biomedical Analysis ◽  
Protection Effect ◽  
Dermal Irritation ◽  
Oecd Guideline

Titanium dioxide, a physical sunscreen, is a metal oxide which reflects and disperses incident UV radiation by an optical mechanism. Sun protect factor (SPF) indicates the level of protection from UV rays. This study aims to prepare titanium dioxide sunscreen cream and evaluate its SPF. Sunscreen cream was first prepared by emulsification method, and then mixed with titanium dioxide. As a result, the sunscreen cream loaded with 5% titanium dioxide had good visual performance, physical stability, and medium UV protection effect with SPF 20+. Keywords Titanium dioxide, sunscreen, SPF. References [1] K. Morabito, N.C. Shapley, et al. Review of sunscreen and the emergence of non‐conventional absorbers and their applications in ultraviolet protection, International journal of cosmetic science. 33(5) (2011), 385-390. https://doi.org/10.1111/j.1468-2494.2011.00654.x.[2] Schalka Sergio, Reis Vitor Manoel Silva dos. Sun protection factor: meaning and controversies, Anais brasileiros de dermatologia. 86(3) (2011) 507-515. [3] Serpone Nick, Dondi Daniele, et al. Inorganic and organic UV filters: Their role and efficacy in sunscreens and suncare products, Inorganica Chimica Acta. 360(3) (2007) 794-802. https://doi.org/10.1016/j.ica.2005.12.057.[4] COLIPA. Method for in vitro determination of uva protection, (2011), 17-19.[5] Couteau Céline, Faure Aurélie, et al. Study of the photostability of 18 sunscreens in creams by measuring the SPF in vitro, Journal of pharmaceutical and biomedical analysis. 44(1) (2007) 270-273. https://doi.org/10.1016/j.jpba.2007.01.052.[6] ISO (2010), Biological evaluation of medical devices-Part 10: Tests for irritation and skin sensitization, 10.[7] OECD (2015), OECD Guideline for testing of chemicals: Acute Dermal Irritation/Corrosion, 404.      

In vitro determination of sun protection factor and chemical stability of Rosa kordesii extract gel

2013 ◽  
Vol 7 (6) ◽  
pp. 520-524 ◽  
Author(s):  
Pratik P. Maske ◽  
Sachin G. Lokapure ◽  
Dhanashri Nimbalkar ◽  
Shobharaj Malavi ◽  
John I. D'souza
Keyword(s):  
Chemical Stability ◽  
Sun Protection ◽  
Protection Factor ◽  
Sun Protection Factor

scholarly journals The Impact of Titanium Dioxide Type Combined with Coffee Oil Obtained from Coffee Industry Waste on Sunscreen Product Performance

Dermato ◽  
2021 ◽  
Vol 1 (1) ◽  
pp. 2-17
Author(s):  
Bruna G. Chiari-Andréo ◽  
Joana Marto ◽  
Andreia Ascenso ◽  
Carlos Carneiro ◽  
Laura Rodríguez ◽  
...  
Keyword(s):  
Titanium Dioxide ◽  
Uv Light ◽  
Topical Delivery ◽  
Anatase Tio2 ◽  
Protection Factor ◽  
Tio2 Particles ◽  
Wide Range ◽  
Coffee Oil ◽  
The Impact

(1) Background: Titanium dioxide (TiO2) consists of three polymorphs, including anatase, rutile and brookite. This work aimed to elucidate the influence of rutile and anatase forms in the performance of sunscreens formulated with green coffee oil (GCO) from coffee beans discarded in the agri-food industry. (2) Methods: TiO2 particles were characterized in terms of size and wettability. The sunscreens formulated with GCO were characterized regarding the droplet size, rheology, texture profile analysis (TPA), in vitro Sun Protection Factor and Water Resistance Retention. Topical delivery and permeation studies were performed to confirm caffeine release and skin penetration. (3) Results: Particle size distributions of rutile and anatase TiO2 particles were similar, however, smaller droplets as well as decreased viscosity and increased thixotropy were obtained for anatase TiO2 and GCO formulation compared to rutile form formulations. Notwithstanding, all formulations exhibited linear viscoelastic behavior. Regarding the TPA, a wide range of mechanical properties improved mainly by GCO rather than TiO2 form has been demonstrated. The influence of TiO2 form on UV protection was better evidenced in absence of GCO. The sunscreen formulations containing GCO presented a favorable topical delivery as confirmed by caffeine release and permeation. (4) Conclusions: Both TiO2 forms combined with GCO provided suitable properties including an effective ultraviolet (UV)-light protection.

scholarly journals Physical Properties, Chemical Analysis, and Evaluation of Antimicrobial Response of New Polylactide/Alginate/Copper Composite Materials

Marine Drugs ◽  
2020 ◽  
Vol 18 (12) ◽  
pp. 660
Author(s):  
Marcin H. Kudzin ◽  
Maciej Boguń ◽  
Zdzisława Mrozińska ◽  
Anna Kaczmarek
Keyword(s):  
Antifungal Susceptibility ◽  
Attenuated Total Reflection ◽  
Composite Fibers ◽  
Protection Factor ◽  
Average Pore ◽  
Ultraviolet Protection Factor ◽  
Susceptibility Tests ◽  
Copper Composite

In recent years, due to an expansion of antibiotic-resistant microorganisms, there has been growing interest in biodegradable and antibacterial polymers that can be used in selected biomedical applications. The present work describes the synthesis of antimicrobial polylactide-copper alginate (PLA–ALG–Cu2+) composite fibers and their characterization. The composites were prepared by immersing PLA fibers in aqueous solution of sodium alginate, followed by ionic cross-linking of alginate chains within the polylactide fibers with Cu(II) ions to yield PLA–ALG–Cu2+ composite fibers. The composites, so prepared, were characterized by scanning electron microscopy (SEM), UV/VIS transmittance and attenuated total reflection Fourier-transform infrared spectroscopy ATR-FTIR, and by determination of their specific surface area (SSA), total/average pore volumes (through application of the 5-point Brunauer–Emmett–Teller method (BET)), and ability to block UV radiation (determination of the ultraviolet protection factor (UPF) of samples). The composites were also subjected to in vitro antimicrobial activity evaluation tests against colonies of Gram-negative (E. coli) and Gram-positive (S. aureus) bacteria and antifungal susceptibility tests against Aspergillus niger and Chaetomium globosum fungal mold species. All the results obtained in this work showed that the obtained composites were promising materials to be used as an antimicrobial wound dressing.

scholarly journals Multifunctional Cosmetic Containing Blueberry and Tinosorb M®- Loaded Microparticles Improves Sunscreen Performance

2019 ◽  
Vol 9 (2) ◽  
pp. 241-248
Author(s):  
Daiana Schiavon ◽  
Daniela Novello Martini ◽  
Gabriela Brocco ◽  
Júlia Scherer Santos ◽  
Ana Paula Anzolin ◽  
...  
Keyword(s):  
Physical Stability ◽  
Tape Stripping ◽  
Uv Filters ◽  
Protection Factor ◽  
Physicochemical Stability ◽  
In Silico Modeling ◽  
Aging Properties ◽  
Anti Oxidant

Purpose: We aimed to evaluate the effect of blueberry extract and microparticles (MPs) on sunscreen performance of multifunctional cosmetics. Octocrylene (OCT), benzophenone-3 (BENZ-3) and Tinosorb® M (MBBT) were employed as UV filters. Methods: An in-silico modeling was used to determine the UV filters concentrations to obtain high values of sunscreen protection factor (SPF) and UVA protection factor (UVA-PF). MBBT and blueberryloaded microparticles (MPMB+B) and MBBT-loaded microparticles (MPMBBT) were prepared by spraydrying. OCT and BENZ-3 were added in the oil phase of cosmetics. Cosmetics A and B contained MPMB+B and MPMBBT, respectively, and cosmetic C was prepared without MP. Characterization, physicochemical stability and in vitro SPF was performed. UV filters distribution in human stratum corneum (SC) for each cosmetic was performed. Anti-oxidant activity of blueberry extract was evaluated. Results: Sunscreen combination with the highest SPF was selected for formulations. Formulations A and B maintained their rheological behavior over time, unlike formulation C. In-vitro SPFs for formulations A, B and C were 51.0, 33.7 and 49.6, respectively. We also developed and validated a method for analysis of the UV filters by HPLC/ PDA suitable for the in-vivo assay. In Tape stripping test, MBBT showed SC distribution similar for all cosmetic formulations. OCT and BENZ-3 distribution to formulation A and C was also similar. Blueberry extract showed antioxidant capacity of 16.71 μg/mL equivalent to vitamin C. Conclusion: Cosmetics containing MPs presented better physical stability. Blueberry increased the photoprotective capacity of the formulations and added extra benefits due to its anti-oxidant and anti-aging properties.

scholarly journals Preparation and Evaluation of Nanoemulgels Containing a Combination of Grape Seed Oil and Anisotriazine as Sunscreen

2020 ◽  
Vol 8 (B) ◽  
pp. 994-999
Author(s):  
Anayanti Arianto ◽  
Desi Yet Lie Lie ◽  
Sumaiyah ◽  
Hakim Bangun Bangun
Keyword(s):  
Seed Oil ◽  
Physical Stability ◽  
Grape Seed ◽  
Protection Factor ◽  
Transmission Electron Microscopy Analysis ◽  
Cycling Test ◽  
Transmission Electron ◽  
Grape Seed Oil ◽  
Droplet Morphology

BACKGROUND: Grape seed oil contains Vitamin E which acts as skin antioxidant and natural ultraviolet (UV) absorbent and anisotriazine is used as chemical absorbent. Sun protection factor (SPF) value of the sunscreen and physical stability can be increased using a combination of grape seed oil and anisotriazine as sunscreen material and preparation by nanotechnology. AIM: The objective of this study was to prepare and evaluate physical stability and in vitro SPF value of sunscreen nanoemulgel containing grape seed oil and anisotriazine. METHODS: Nanoemulgels containing 4% grape seed oil and anisotriazine (1.6% and 3.2%) were formulated by adding 2% of Carbopol 940 gel to the optimized nanoemulsions formulation with a ratio of nanoemulsion and gel 4:1. The nanoemulgels were evaluated physical stability during storage for 12 weeks at variations of temperature, centrifugation, and cycling test. SPF values of nanoemulgels were determined by UV–visible spectrophotometric method and compared to emulgel. Droplet morphology observation of nanoemulgel using transmission electron microscope. RESULTS: The results of this study showed that sunscreen nanoemulgel containing 4% grape seed oil and 3.2% anisotriazine had average droplet size of 187.5 nm, physically stable during experiment for 12 weeks at variation of temperature and after centrifugation and cycling test, but the sunscreen emulgel showed a phase separation. The SPF of nanoemulgel containing a combination of 4% grape seed oil and 3.2%, nanoemulgel without anisotriazine, and emulgel formulation was 19.325 ± 0.232, 11.169 ± 0.113, and 11.913 ± 0.161, respectively. Transmission electron microscopy analysis of droplet morphology showed that this nanoemulgel formulation formed a spherical globule. CONCLUSION: The sunscreen nanoemulgel formulation containing combination of 4% grape seed oil and 3.2% anisotriazine more stable than sunscreen emulgel during experiment for 12 weeks at room temperature and showed the SPF value higher compared to emulgel containing 4% grape seed oil and 3.2% anisotriazine and nanoemulgel without anisotriazine.

scholarly journals A Novel Quality Control Method for the Determination of the Refractive Index of Oil-in-Water Creams and Its Correlation with Skin Hydration

Cosmetics ◽  
2021 ◽  
Vol 8 (3) ◽  
pp. 74
Author(s):  
Deborah Adefunke Adejokun ◽  
Kalliopi Dodou
Keyword(s):  
Control Method ◽  
Sensory Properties ◽  
Skin Hydration ◽  
Protection Factor ◽  
Predictive Tool ◽  
Quality Control Method ◽  
Critical Wavelength ◽  
Oil In Water

The sensory properties of cosmetic products can influence consumers’ choice. The accurate correlation of sensory properties, such as skin hydration, with the material properties of the formulation could be desirable. In this study, we aimed to demonstrate a new method for the in vitro measurement of the refractive indices (RIs) of turbid creams. The critical wavelength of each cream was obtained through direct measurement using a sun protection factor (SPF) meter; the wavelength value was then applied in the Sellmeier equation to determine the RI. The results obtained from the in vitro skin hydration measurement for each cream correlated with their RI values. This suggests that RI measurements could be a useful predictive tool for the ranking of creams in terms of their skin hydration effects.

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