scholarly journals Antibiotic Control In Times Of COVID-19

2020 ◽  
Vol 20 (4) ◽  
pp. 758-759
Author(s):  
Christian Manuel Chiara Chilet ◽  
Marcos Saavedra Velasco
Keyword(s):  
Antibiotic Control

scholarly journals Evaluation of the Efficacy of a Bacteriophage in the Treatment of Pneumonia Induced by Multidrug ResistanceKlebsiella pneumoniaein Mice

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Fang Cao ◽  
Xitao Wang ◽  
Linhui Wang ◽  
Zhen Li ◽  
Jian Che ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Burst Size ◽  
Multidrug Resistant ◽  
Lung Lesion ◽  
Lytic Bacteriophage ◽  
Short Latent Period ◽  
Dose Dependent ◽  
Antibiotic Control

Multidrug-resistantKlebsiella pneumoniae(MRKP) has steadily grown beyond antibiotic control. However, a bacteriophage is considered to be a potential antibiotic alternative for treating bacterial infections. In this study, a lytic bacteriophage, phage 1513, was isolated using a clinical MRKP isolate KP 1513 as the host and was characterized. It produced a clear plaque with a halo and was classified as Siphoviridae. It had a short latent period of 30 min, a burst size of 264 and could inhibit KP 1513 growthin vitrowith a dose-dependent pattern. Intranasal administration of a single dose of 2 × 109 PFU/mouse 2 h after KP 1513 inoculation was able to protect mice against lethal pneumonia. In a sublethal pneumonia model, phage-treated mice exhibited a lower level ofK. pneumoniaeburden in the lungs as compared to the untreated control. These mice lost less body weight and exhibited lower levels of inflammatory cytokines in their lungs. Lung lesion conditions were obviously improved by phage therapy. Therefore, phage 1513 has a great effectin vitroandin vivo, which has potential to be used as an alternative to an antibiotic treatment of pneumonia that is caused by the multidrug-resistantK. pneumoniae.

METHODS FOR REDUCING THE DETECTION LIMIT OF IMMUNOCHROMATOGRAPHIC TEST SYSTEMS FOR ANTIBIOTIC CONTROL IN HONEY

2021 ◽  
Vol 1 (19) ◽  
pp. 219-220
Author(s):  
L. Barshevskaya ◽  
D. Sotnikov ◽  
A. Zherdev ◽  
B. Dzantiev
Keyword(s):  
Molecular Weight ◽  
Detection Limit ◽  
Low Molecular Weight ◽  
Immunochromatographic Test ◽  
Test Systems ◽  
Antibiotic Control

Methods for increasing the sensitivity of immunochromatographic test systems for the determination of low molecular weight analytes are proposed. The developed analysis schemes were tested in the determination of sulfonylamide and chloramphenicol in honey.

ANTIBIOTIC CONTROL OF TISSUE REACTIONS IN DOGS VACCINATED WITH VIABLE CELLS OF COCCIDIOIDES IMMITIS1

1964 ◽  
Vol 87 (5) ◽  
pp. 1216-1220 ◽  
Author(s):  
Merida W. Castleberry ◽  
John L. Converse ◽  
Peter J. Soto
Keyword(s):  
Viable Cells ◽  
Tissue Reactions ◽  
Antibiotic Control

Quality indicators for antibiotic control programmes

2002 ◽  
Vol 50 (3) ◽  
pp. 165-169 ◽  
Author(s):  
D. Nathwani ◽  
K. Gray ◽  
H. Borland
Keyword(s):  
Quality Indicators ◽  
Control Programmes ◽  
Antibiotic Control

scholarly journals Anti-Methicillin-Resistant Staphylococcus aureus (MRSA) of Ethanol Extract of God's Crown (Phaleria macrocarpa) Leaves, Peel, and Fruit Flesh

2020 ◽  
Vol 31 (2) ◽  
pp. 81
Author(s):  
Rani Afifah Nur Hestiyani ◽  
Tri Okmawati Handini
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Activity ◽  
Antibacterial Agent ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Ethanolic Extract ◽  
Ethanol Extract ◽  
Methicillin Resistant ◽  
Fruit Flesh ◽  
Phaleria Macrocarpa ◽  
Antibiotic Control

Methicillin-resistant Staphylococcus aureus (MRSA) is a pathogen that becomes the main concern since it is a multidrug-resistant organism and causes high morbidity and mortality. This study aimed to investigate the antibacterial activity of ethanolic extract of Phaleria macrocarpa leaves, peel, and fruit flesh on MRSA. This study was an experimental laboratory study with a post-test only control group design to assess the antibacterial activity of ethanolic extract from leaves, peel, and fruit flesh of Phaleria macrocarpa against MRSA ATCC 43300 and MRSA clinical isolates using a disk diffusion method. Extracts from the leaves, peel, and flesh of Phaleria macrocarpa had potential as an antibacterial agent against MRSA ATCC 43300 at a concentration of 40%, although not yet equivalent to antibiotic control. The ethanol extract of Phaleria macrocarpa peel at a concentration of 30-40% had potential as an antibacterial agent against MRSA clinical isolates, although not yet equivalent to antibiotic control. Further research needs to be performed so that Phaleria macrocarpa extract can be a potential source of subsequent antibacterial development against MRSA.

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