Objective: Biological dressings are water-resistant to bacteria, and generate the most physiological
interfacebetween the wound surface and the environment. Collagen dressings have other superiority
over conventional dressings in terms of ease of application and being natural, non-immunogenic, non-pyrogenic, hypoallergenic, and pain-free.
Materials And Methods: The data of 120 patients with chronic wounds of diverse aetiologies and with signify age 43.7 years
were accumulated and analyzed. The patients had been treated with collagen or other conventional dressing substance. The
patients were split into two groups; 'Collagen group' and 'Conventional group', For the cause of comparison. 60 patients
wereincluded in both groups. For assessment the wound characteristics in size, edge, oor, granulation tissue, and wound
swab were recorded. With starting treatment, appearance of granulation tissue, completeness of healing, require for skin
grafting, and patients' satisfaction was noted in both groups.
Results: Sixty percentage of the 'collagen group' wounds and only forty-two percentage of the 'conventionalgroup' wounds were
sterile (P=0.04) within two weeks of treatment. Healthy granulation tissue seemed earlier over collagen-dressed woundsthan
over conventionally treated wounds (P=0.04). After eight weeks, (87%) of 'collagen group' wounds and (80%) of 'conventional
group' wounds were >75% healed (P=0.21). In the 'collagen group' eight patients and twelvein the 'conventional group'
required partial split-skin grafting (P=0.05). Collagen-treated patients enjoyed early.
Conclusion: No remarkable better results were found in terms of complete of healing of burn andchronic wounds between
collagen dressing and conventional dressing. Collagen dressing, however, mayavoid the require of skin grafting, and provides
additional benet of patients' comfort.