scholarly journals Resolution of Post-Surgical Hypergranulation Tissue with Topical Aluminum Chloride

2018 ◽  
Vol 2 (5) ◽  
Author(s):  
Giselle Prado ◽  
Anna Nichols ◽  
Martin Zaiac

Hypergranulation is the extension of granulation tissue beyond the required amount to close a tissue defect. We report our experience using aluminum chloride to treat a series of two patients with hypergranulation tissue. Both patients had lengthy treatment courses after Mohs surgery with growth of hypergranulation tissue that resolved once aluminum chloride was placed on the wound. Aluminum chloride is a useful hemostatic agent frequently employed in dermatology. It is a readily available and low-cost option for management of hypergranulation after dermatologic procedures. Chronic wounds are a common treatment challenge for clinicians. Due to its affordability and availability, clinicians may consider topical aluminum chloride when managing post-surgical hypergranulation tissue.

2021 ◽  
Vol 48 (4) ◽  
pp. 460-466
Author(s):  
Seolah Back ◽  
Joonhaeng Lee ◽  
Jongbin Kim ◽  
Miran Han ◽  
Jong Soo Kim

The purpose of this study was to compare the effect of the hemostatic agent containing aluminum chloride with hemostatic agent containing ferric sulfate on the shear bond strength of resin-modified glass ionomer cement(RMGIC) to dentin in primary tooth. Twenty extracted non-carious human primary teeth were collected in this study. The specimens were cut to expose dentin and polished. The specimens were randomly seperated into 3 groups for treatment; group I: polyacrylic acid(PAA), RMGIC; group II: aluminum chloride, PAA, RMGIC; group III: ferric sulfate, PAA, RMGIC Ten specimens from each group were subjected to shear bond strength test. The mean shear bond strength of each group was as follows: 10.07 ± 1.83 MPa in Group I, 7.62 ± 0.78 MPA in group II, 5.23 ± 0.78 MPa in group III. There were significant differences among all groups(p < 0.001). In conclusion, both aluminum chloride hemostatic agent and ferric sulfate hemostatic agent decreased the shear bond strength of RMGIC to dentin. And ferric sulfate hemostatic agent decreased the shear bond strength of RMGIC more than the aluminium chloride hemostatic agent.


2010 ◽  
Vol 75 (4) ◽  
pp. 423-431 ◽  
Author(s):  
Bahman Tamami ◽  
Nasrolahi Shirazi ◽  
Parvanak Borujeni

Crosslinked polystyrene-supported aluminum chloride (Ps-AlCl3) is a stable, recyclable and environmental friendly heterogeneous catalyst for the condensation of indole with aldehydes and ketones to afford bis-indolylmethanes. In addition, (Ps-AlCl3) shows satisfactory selectivity in the reaction of mixtures of an aldehyde and a ketone with indole. Although AlCl3 is a water sensitive, corrosive and environmentally harmful compound, Ps-AlCl3 is a stable and water-tolerant species. The mild reaction conditions, short reaction times, easy work-up, high to excellent yields, chemoselectivity, reuse of the catalyst for at least ten times without significant change in its catalytic activity, low cost, and easy preparation and handling of the polymeric catalyst are obvious advantages of the present method.


2021 ◽  
Vol 3 (6) ◽  
pp. 4-7
Author(s):  
Hendro Sudjono Yuwono

The coffee powder has inherent capabilities as an antioxidant, anti-inflammatory, and antimicrobial. It is a topical wound dressing for acute and chronic wounds, encouraging results different from the wound dressing known today. It is named the new paradigm of wound management. The study of coffee powder since 2003 as a topical wound dressing has created an understanding condemn to disturb the cells in the wound bed. A thin layer of coffee powder should stay in place to ensure safety, covering superficial wound cells’ growth. The remained thin layer of coffee powder has created minimum detached wound cells. Wound healing provides effectiveness for acute and chronic wounds resulted in low cost, easy to get, acceptable scar, non-traumatic, pleasant scent, and not scary to the patients. The utilization of antioxidant, anti-inflammatory, and antibacterial capacities anticipates the injury of the new growth of epithelial cells at the wound bed. It makes better cell proliferation, proper scar formation and safe naturally. Its simplicity in wound management procedures helps improve public health efforts. Hence, it suggested that the coffee powder has the capabilities of the best topical wound dressing.


2021 ◽  
Vol 19 (1) ◽  
pp. 05-09
Author(s):  
Sandesh M ◽  

Background: Diabetic foot infections are the leading cause of hospitalization morbidity and mortality in diabetics worldwide In India it accounts for 20% of hospitalizations. honey has been investigated to treat ulcers like pressure ulcers, venous ulcers, diabetic ulcers, traumatic wounds and burns. Phenytoin is also now known to promote wound healing and can be an alternative to normal saline specifically in chronic wounds related to diabetes. The present study compares these two modalities in management of diabetic ulcers. Objective: To compare the efficacy of topical phenytoin vs topical honey in chronic diabetic ulcers in terms of rate of wound healing, granulation tissue formation and quality of graft bed for skin grafting. Methods: A comparative prospective study of 50 patients with chronic diabetic ulcers selected based on a predefined criteria divided into two groups: Group A (Phenytoin group) (n=25) and Group B (honey group) (n=25). Final wound area was measured on 30th day. Comparison between the wound size reduction among two groups done at end of 30th day. Outcome was measured in terms of wound reduction, granulation tissue formation and quality of bed for skin grafting between the two groups. Results: This study has shown faster rate of wound healing, better granulation tissue formation and quality graft bed for skin grafting in patients who received topical phenytoin dressing as compared to topical honey dressing.


2021 ◽  
pp. 43-45
Author(s):  
Sujeet Kumar Bharti ◽  
Kirti Priya

Objective: Biological dressings are water-resistant to bacteria, and generate the most physiological interfacebetween the wound surface and the environment. Collagen dressings have other superiority over conventional dressings in terms of ease of application and being natural, non-immunogenic, non-pyrogenic, hypoallergenic, and pain-free. Materials And Methods: The data of 120 patients with chronic wounds of diverse aetiologies and with signify age 43.7 years were accumulated and analyzed. The patients had been treated with collagen or other conventional dressing substance. The patients were split into two groups; 'Collagen group' and 'Conventional group', For the cause of comparison. 60 patients wereincluded in both groups. For assessment the wound characteristics in size, edge, oor, granulation tissue, and wound swab were recorded. With starting treatment, appearance of granulation tissue, completeness of healing, require for skin grafting, and patients' satisfaction was noted in both groups. Results: Sixty percentage of the 'collagen group' wounds and only forty-two percentage of the 'conventionalgroup' wounds were sterile (P=0.04) within two weeks of treatment. Healthy granulation tissue seemed earlier over collagen-dressed woundsthan over conventionally treated wounds (P=0.04). After eight weeks, (87%) of 'collagen group' wounds and (80%) of 'conventional group' wounds were >75% healed (P=0.21). In the 'collagen group' eight patients and twelvein the 'conventional group' required partial split-skin grafting (P=0.05). Collagen-treated patients enjoyed early. Conclusion: No remarkable better results were found in terms of complete of healing of burn andchronic wounds between collagen dressing and conventional dressing. Collagen dressing, however, mayavoid the require of skin grafting, and provides additional benet of patients' comfort.


1980 ◽  
Vol 26 (4) ◽  
pp. 548-550 ◽  
Author(s):  
Pierre Payment ◽  
Michel Trudel

A simple low cost proportioning injector can effectively add chemicals such as aluminum chloride, hydrochloric acid, and sodium thiosulfate, to condition large volumes of water to detect viruses by adsorption to selected filters.


2006 ◽  
Vol 72 (2) ◽  
pp. 129-131 ◽  
Author(s):  
Rob Schuster ◽  
Arash Moradzadeh ◽  
Kenneth Waxman

Chronic wounds in difficult locations pose constant challenges to health care providers. Negative-pressure wound therapy is a relatively new treatment to promote wound healing. Laboratory and clinical studies have shown that the vacuum-assisted closure (VAC) therapy increases wound blood flow, granulation tissue formation, and decreases accumulation of fluid and bacteria. VAC therapy has been shown to hasten wound closure and formation of granulation tissue in a variety of settings. Accepted indications for VAC therapy include the infected sternum, open abdomen, chronic, nonhealing extremity wounds and decubitus ulcers. We report the first case of VAC therapy successfully used on a large infected wound to the face to promote healing.


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