scholarly journals Development of Quality Control Parameters for Standardization of Cyperus scariosus R.Br. Roots

Author(s):  
Nidhi Sharma ◽  
Sumitra Singh ◽  
Shailendra Kumar Singh

Cyperus scariosus R.Br. (Family: Cyperaceae) is perennial and delicate slender sedge found wildly in damp or marshy areas. The present study was undertaken for the development of quality control parameters of Cyperus scariosus R.Br. roots. The study includes determination of various standardization parameters like morphological characters, microscopic studies, histochemical detection and physicochemical evaluation of Cyperus scariosus R.Br. roots. The morphological studies exhibited the organoleptic and surface characteristics of the roots. The microscopic study showed the presence of various characteristic features of roots like cortex, lignified endodermis, pericycle, scalariform xylem vessels, tracheids and phloem. Physicochemical constants such as moisture content, ash values, extractive values, swelling index and foaming index were established. Preliminary phytochemical analysis of root extracts revealed the presence of alkaloids, anthraquinone glycosides, phenols, flavonoids, tannins, saponins, steroids and terpenoids. These pharmacognostic features established in this study would helpful for the establishment of pharmacopoeial standards to facilitate quality control and correct identification of Cyperus scariosus R.Br. roots, also to minimize adulteration and substitution.

2018 ◽  
Vol 7 (3) ◽  
pp. 312-318
Author(s):  
A Kanakiya ◽  
◽  
H Padalia ◽  
J Pande ◽  
S Chanda ◽  
...  

The halophyte Limonium stocksii (Boiss) Kuntze belongs to the family Plumbaginaceae. In the present work, pharmacognostic studies of this medicinal halophyte was attempted which included physicochemical, phytochemical, macroscopic, microscopic studies and organoleptic evaluation. The plant powder characteristics were also elucidated. The physicochemical analyses were done by using WHO recommended parameters such as loss on drying, ash values (total ash, water soluble ash, acid insoluble ash, sulphated ash, carbonated ash, nitrated ash), extractive values. The qualitative phytochemical analysis revealed the presence of saponins, steroids and coumarins in maximum amount in crude as well as in various solvent extracts. The morphological studies exhibited the organoleptic and surface characteristics of the plant and its parts. The microscopic study showed the presence of various characteristics of whole plant like palisade tissue, metaxylem, protoxylem, phloem showed companion cells, bicollateral type of vascular bundles, parenchyma, rosette calcium oxalate crystals and paracytic stomata. The pharmacognostic characters enlisted in this study will help in identification of the crude drug; the standardization parameters laid down will ensure the efficacy of drug and also distinguish the drug from its adulterants. The distinguishing characters will also be helpful for the preparation of monograph of this halophytic plant


Author(s):  
Almas Tarannum ◽  
Prathviraj Puranik ◽  
Suma V. Mallya

Ayurveda is the healing medicine. Dosha, Dhatu, Mala and Agni play important role in maintaining health of a person, but without equilibrium of Atma, Indriya and Manas they are helpless. Manas is one entity which is the controller of health. There are several herbs which have direct impact on Manas, among them Mandukaparni is one. Swarasa of Mandukaparni is highly effective, but it is not easily available for children. This study is intended to make Syrup form of Mandukaparni and evaluate its pharmacognostical parameters. According to the methodology refractive index, total solids, specific gravity, reducing and non Reducing sugar and HPTLC parameters were assessed. The results were found to be genuine fulfilling the standard protocol. This study is under taken to evaluate the pharmacognostic properties of Mandukaparni syrup.


Author(s):  
Komal D. Jani ◽  
Dharmendra P. Jani

Otomycosis denotes diffuse otitis externa due to fungal infections. The fungii are usually secondary invaders of the tissue rendered susceptible by bacterial infection, physical injury or excessive accumulation of cerumen in the external auditory canal. Karnasraava means discharge from ear which can be correlated with otorrhoea. Karnasraava (discharge) is one of symptom of otomycosis. Arka Taila has been mentioned in Shaarangadhara is very simple formula having ingredients i.e. Haridraa (Curcuma longa), Arka Patra Swarasa (Calotropis procera) and Sarshapa Taila (Brassica campetries). The quality control parameters resulted after scientific evaluation of Arka Taila can be used as reference standard for quality control or quality assurance of a pharmaceutical industry in order to have a proper quality check over its preparation and processing.


2001 ◽  
Vol 7 (2) ◽  
pp. 93-95
Author(s):  
P.C. Fuchs ◽  
A.L. Barry ◽  
S.D. Brown ◽  
M.M. Traczeski

2019 ◽  
Vol 1 (9) ◽  
Author(s):  
Anand Prakash ◽  
Pracheta Janmeda ◽  
Purnima Pathak ◽  
Sneha Bhatt ◽  
Vinay Sharma

2020 ◽  
Vol 136 ◽  
pp. 105231
Author(s):  
Luis Quintero-Fong ◽  
Francisco Ramírez ◽  
Gabriela Juárez ◽  
Yeudiel Gómez ◽  
Lucy Tirado ◽  
...  

1996 ◽  
Vol 40 (7) ◽  
pp. 1633-1639 ◽  
Author(s):  
P C Fuchs ◽  
A L Barry ◽  
S D Brown

More than 3,000 consecutive clinical bacterial isolates from 10 U.S. medical centers were subjected to standard broth microdilution and disk diffusion tests to determine their susceptibilities to levofloxacin, ofloxacin, D-ofloxacin, and ciprofloxacin. Levofloxacin was confirmed to be twice as active as ofloxacin and to have activity comparable to that of ciprofloxacin, with minor variations in activity against some species. The prevalence of resistant isolates was 7.1% to levofloxacin, 9.3% to ciprofloxacin, and 11.2% to ofloxacin. The susceptibilities of some species to the quinolones were less than those reported in previous studies. Pseudomonas aeruginosa isolates had the greatest variability in their susceptibilities to the three drugs between the participating centers. Two proposed zone size breakpoints for levofloxacin disk tests yielded similar low error rates. Ofloxacin and ciprofloxacin susceptibility test results correlated reasonably well with those of levofloxacin and could be used as surrogate indicators of levofloxacin susceptibility, but that resulted in some serious errors, and thus, direct testing of levofloxacin susceptibility is preferable. Replicate testing of standard quality control strains confirmed the established and proposed quality control parameters for all three quinolones tested.


2005 ◽  
Vol 222 (3-4) ◽  
pp. 281-285 ◽  
Author(s):  
Antonio J. Pérez-López ◽  
Domingo Saura ◽  
José Lorente ◽  
Ángel A. Carbonell-Barrachina

Sign in / Sign up

Export Citation Format

Share Document