К вопросу о роли материнского фактора при дакриоцистите новорожденных

Purpose. To study the characteristics of neonatal dacryocystitis, taking into account the state of health of their mothers and its possible impact on the development of neonatal dacryocystitis. Material and methods. A retrospective analysis of 724 outpatient medical records and case histories of children with neonatal dacryocystitis (868 eyes) and an assessment of the health status of their mothers were carried out. Results. It was found that children with neonatal dacryocystitis had concomitant somatic pathology in 11.6% of cases and congenital eye pathology in 2.3%. Among the somatic pathology, there were diseases of the respiratory and cardiovascular systems, disorders of the musculoskeletal system and lesions of the central nervous system, as well as other unexplained diseases. The burdened heredity according to neonatal dacryocystitis was found in 23.5% of children. Mothers of children with neonatal dacryocystitis suffered from somatic diseases in 14.4% of cases and gynecological pathology in 8.5% of cases. Sexually transmitted diseases were in 19.5% of mothers. Influenza or acute respiratory viral infection in the first trimester of pregnancy was suffered by 65.9% of mothers of children with DN. The pathological course of the first trimester of pregnancy was observed in 74.7% of mothers. Conclusion. The frequency of somatic, gynecological diseases, genital infections, influenza or acute respiratory viral infections during pregnancy, the pathological course of pregnancy in mothers of children with neonatal dacryocystitis, and somatic diseases in newborns, in addition to inflammation of the lacrimal sac, suggest the presence of the so-called, “maternal factor” – maternal health, contributing to the development, along with neonatal dacryocystitis, pathological clinical conditions due to possible intrauterine infection of the fetus, which corresponds to the infectious-inflammatory theory of development of neonatal dacryocystitis. Key words: children, maternal factor, inflammation of the lacrimal sac, neonatal dacryocystitis.

Download Full-text

Relative Risk Assessment of Intrauterine Infection of the Fetus During Cytomegalovirus Infection in Early Pregnancy

Acta biomedica scientifica ◽

10.29413/abs.2019-4.3.6 ◽

2019 ◽

Vol 4 (3) ◽

pp. 45-51 ◽

Cited By ~ 1

Author(s):

K. K. Petrova

Keyword(s):

Risk Assessment ◽

Relative Risk ◽

Pregnant Women ◽

Early Pregnancy ◽

Intrauterine Infection ◽

First Trimester ◽

Cmv Infection ◽

Significant Difference ◽

First Trimester Of Pregnancy ◽

Relative Risk Assessment

Background. Intrauterine fetal infection (IUI), the common cause of which is the cytomegalovirus (CMV), occupies one of the first places in the structure of perinatal morbidity and mortality. There are no data on the relative risk assessment of IUI at the exacerbation of CMV infection and its delitescent course in first trimester of pregnancy in the literature.Aim: to calculate the relative risks of fetal IUI in pregnant women with exacerbation of CMV infection in the first trimester of pregnancy.Methods. A retrospective review of the labor and delivery medical records and prenatal records of 104 CMV-seropositive women was carried out. Fifty of these women had an exacerbation of CMV infection in the first trimester of pregnancy – main group and 54 of them were with delitescent course of the disease (comparison group).Results. A comparative analysis of ultrasound and morphological markers of IUI with risk assessment depending on the course of CMV infection in the first trimester of pregnancy has been carried out. A high risk of placental structure abnormalities, as well as amniotic fluid and fetal membranes, fetal and placental blood flow pathology, onset of choroid plexus cyst and fetal growth restriction was found, with a statistically significant difference in the group of pregnant women with exacerbation of CMV infection in the first trimester of pregnancy.Conclusion. The findings suggest that the exacerbation of CMV infection in early pregnancy is a risk factor for IUI.

Download Full-text

Epidemiology of ectopic pregnancy at Laquintinie Douala hospital (Cameroon): prevalence survey, clinical profile, therapeutic and transfusion issues

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20205752 ◽

2020 ◽

Vol 10 (1) ◽

pp. 44

Author(s):

Henri Essome ◽

Thomas O. Egbe ◽

Gregory E. Halle ◽

Théophile N. Nana ◽

Merlin Boten ◽

...

Keyword(s):

Risk Factors ◽

Ectopic Pregnancy ◽

First Trimester ◽

Sexual Partners ◽

Age Group ◽

Prevalence Survey ◽

Multiple Sexual Partners ◽

Sexually Transmitted ◽

First Trimester Of Pregnancy ◽

Therapeutic Profile

Background: Pregnancy is a serious pathology of the first trimester of pregnancy and is the leading cause of death. The objective of our work was to determine the hospital prevalence of ectopic pregnancy (EP), to describe the epidemiological, clinical and therapeutic profile given the often-haemorrhagic context at Laquintinie Hospital in Douala.Methods: We carried out a retrospective study over 10 years, from January 1st, 2007 to December 31st, 2016, using the operating theatre registers and the files of patients admitted during this period for ectopic pregnancy in the gynaecology and obstetrics department of the Laquintinie Hospital in Douala.Results: A total of 905 cases of EP for 32,595 deliveries were recorded, for an overall incidence of 2.8%. EP mainly affected the age group of 25 to 35 (60.6%), single people (57.9%) and housewives (46.6%). The risk factors found were similar to those of cervical cancer, namely multiple sexual partners (80.4%), the precocity of sexual intercourse under 18 years (54.1%) and sexually transmitted infections (52.5%). The symptomatic triad (pelvic pain, amenorrhea and metrorrhagia) was found in 46.1% of cases with a respective order of frequency of 96.9%, 77.3% and 63.6% The management was essentially surgical by radical laparotomy (97% of cases). Two of the 07 deaths were due to religious considerations.Conclusions: EP remains a frequent pathology in our environment with a heavy toll of tubal amputations and death.

Download Full-text

SARS-CoV-2 in first trimester pregnancy – does it affect the fetus?

10.1101/2020.06.08.20125195 ◽

2020 ◽

Cited By ~ 1

Author(s):

Nina la Cour Freiesleben ◽

Pia Egerup ◽

Kathrine Vauvert Römmelmayer Hviid ◽

Elin Rosenbek Severinsen ◽

Astrid Marie Kolte ◽

...

Keyword(s):

Pregnant Women ◽

Pregnancy Loss ◽

Viral Infections ◽

First Trimester ◽

Nuchal Translucency ◽

Grey Zone ◽

First Trimester Pregnancy ◽

Trimester Pregnancy ◽

First Trimester Of Pregnancy ◽

Test Serum

AbstractBackgroundSeveral viral infections are known to be harmful to the fetus in the first trimester of pregnancy and can cause increased nuchal translucency thickness and pregnancy loss. Currently, no evidence exists regarding possible effects of SARS-CoV-2 in first trimester pregnancies.MethodsCohort 1 included pregnant women with a double test taken between Feb. 17 and Apr. 23, 2020, during the SARS-CoV-2 epidemic peak in Denmark. The double test was taken as part of the first trimester risk assessment. Cohort 2 included women with a first trimester pregnancy loss before double test. Serum from the double test or from a blood sample, in case of pregnancy loss, was analyzed for SARS-CoV-2 antibodies. The results were correlated to the nuchal translucency thickness and the number of pregnancy losses.ResultsIn total, 1,019 pregnant women with double test and 36 women with pregnancy loss participated in the study. Thirty (2.9%) women had SARS-CoV-2 antibodies in the serum from the double test. All women with pregnancy loss prior to the double test were negative for SARS-CoV-2 antibodies. There were no significant differences in nuchal translucency thickness for women testing positive (n=14) versus negative (p=0.20) or grey zone (n=16) versus negative (p=0.28). In total, 54 women experienced a pregnancy loss of whom two had grey zone or positive SARS-CoV-2 antibodies.ConclusionMaternal SARS-CoV-2 infection did not seem harmful in first trimester pregnancies. Infection had no effect on the nuchal translucency thickness and women with SARS-CoV-2 antibodies were not overrepresented among women with pregnancy loss.

Download Full-text

Catheter Directed Thrombolysis for Deep Vein Thrombosis during the First Trimester of Pregnancy: Two Case Reports

Journal of the Korean Radiological Society ◽

10.3348/jkrs.2008.58.2.127 ◽

2008 ◽

Vol 58 (2) ◽

pp. 127

Author(s):

Kum Rae Kim ◽

Won Kyu Park ◽

Jae Woon Kim ◽

Woo Hyung Kwun ◽

Bo Yang Suh ◽

...

Keyword(s):

Deep Vein Thrombosis ◽

Case Reports ◽

First Trimester ◽

Vein Thrombosis ◽

Catheter Directed Thrombolysis ◽

First Trimester Of Pregnancy ◽

Deep Vein

Download Full-text

FRACTIONAL DETERMINATIONS OF URINARY 17-KETOSTEROIDS IN HYPEREMESIS GRAVIDARUM

Acta Endocrinologica ◽

10.1530/acta.0.0410123 ◽

1962 ◽

Vol 41 (1) ◽

pp. 123-128 ◽

Cited By ~ 6

Author(s):

Pentti A. Järvinen ◽

Sykkö Pesonen ◽

Pirkko Väänänen

Keyword(s):

Hyperemesis Gravidarum ◽

First Trimester ◽

Control Group ◽

Before And After ◽

Daily Urine ◽

First Trimester Of Pregnancy ◽

The Difference

ABSTRACT The fractional determination of 17-ketosteroids in the daily urine was performed in nine cases of hyperemesis gravidarum and in four control cases, in the first trimester of pregnancy both before and after corticotrophin administration. The excretion of total 17-KS is similar in the two groups. Only in the hyperemesis group does the excretion of total 17-KS increase significantly after corticotrophin administration. The fractional determination reveals no difference between the two groups of patients with regard to the values of the fractions U (unidentified 17-KS), A (androsterone) and Rest (11-oxygenated 17-KS). The excretion of dehydroepiandrosterone is significantly higher in the hyperemesis group than in the control group. The excretion of androstanolone seems to be lower in the hyperemesis group than in the control group, but the difference is not statistically significant. The differences in the correlation between dehydroepiandrosterone and androstanolone in the two groups is significant. The high excretion of dehydroepiandrosterone and low excretion of androstanolone in cases of hyperemesis gravidarum is a sign of adrenal dysfunction.

Download Full-text