scholarly journals Functional diseases of the gastrointestinal tract in the context with overlapping functional disorders: current status of the problem

2020 ◽  
Vol 92 (2) ◽  
pp. 111-118
Author(s):  
M. A. Osadchuk ◽  
A. A. Svistunov ◽  
N. V. Kireeva ◽  
M. M. Osadchuk
Keyword(s):  
Health Care ◽  
Gastrointestinal Tract ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Current Status ◽  
Functional Disorders ◽  
Digestive Tube ◽  
Psychosocial Disorders ◽  
Significant Damage ◽  
Course Features

Functional diseases of the gastrointestinal tract cause significant damage to the health care system. Their frequent combination in the same patient with the migration of clinical symptoms throughout the digestive tube is accompanied by continuous exacerbations, refractory to the therapy and severe psychosocial disorders. This review provides data on the main etiopathogenetic factors, clinical manifestations, course features and management tactics for patients with overlapping for the most common functional diseases of the gastrointestinal tract.

scholarly journals ESGE and ESGENA Position Statement on gastrointestinal endoscopy and the COVID-19 pandemic

Endoscopy ◽  
2020 ◽  
Vol 52 (06) ◽  
pp. 483-490 ◽  
Author(s):  
Ian M. Gralnek ◽  
Cesare Hassan ◽  
Ulrike Beilenhoff ◽  
Giulio Antonelli ◽  
Alanna Ebigbo ◽  
...  
Keyword(s):  
Health Care ◽  
Health Care Providers ◽  
European Society ◽  
Health Care Professionals ◽  
Gastrointestinal Endoscopy ◽  
Clinical Manifestations ◽  
Current Status ◽  
Infection Prevention And Control ◽  
Care Providers ◽  
Increased Risk

AbstractWe are currently living in the throes of the COVID-19 pandemic that imposes a significant stress on health care providers and facilities. Europe is severely affected with an exponential increase in incident infections and deaths. The clinical manifestations of COVID-19 can be subtle, encompassing a broad spectrum from asymptomatic mild disease to severe respiratory illness. Health care professionals in endoscopy units are at increased risk of infection from COVID-19. Infection prevention and control has been shown to be dramatically effective in assuring the safety of both health care professionals and patients. The European Society of Gastrointestinal Endoscopy (www.esge.com) and the European Society of Gastroenterology and Endoscopy Nurses and Associates (www.esgena.org) are joining forces to provide guidance during this pandemic to help assure the highest level of endoscopy care and protection against COVID-19 for both patients and endoscopy unit personnel. This guidance is based upon the best available evidence regarding assessment of risk during the current status of the pandemic and a consensus on which procedures to perform and the priorities on resumption. We appreciate the gaps in knowledge and evidence, especially on the proper strategy(ies) for the resumption of normal endoscopy practice during the upcoming phases and end of the pandemic and therefore a list of potential research questions is presented. New evidence may result in an updated statement.

scholarly journals Diseases of biliary tract in the context of association with oncological diseases of the digestive system

2019 ◽  
Vol 91 (12) ◽  
pp. 98-104
Author(s):  
M A Osadchuk ◽  
A A Svistunov ◽  
E D Mironova ◽  
I N Vasil’eva ◽  
N V Kireeva
Keyword(s):  
Risk Factors ◽  
Health Care ◽  
Gastrointestinal Tract ◽  
Health Care System ◽  
Biliary Tract ◽  
Digestive System ◽  
Preventive Measures ◽  
Malignant Neoplasms ◽  
Significant Damage ◽  
Oncological Diseases

Cancers of the gastrointestinal tract are widespread among the population and cause significant damage to the health care system. In order to improve the strategy of preventive measures and the detection of oncological diseases at the early stages, it is necessary to provide timely impact on possible risk factors contributing to the onset and progression of malignant neoplasms. This review demonstrates the association between the pathology of the biliary tract and oncological diseases of the digestive system, discusses the possible mechanisms of the influence of cholelithiasis and cholecystectomy on the development of malignant neoplasms of various parts of the gastrointestinal tract.

scholarly journals Clinical manifestations of Covid-19 disease; Exploring the experiences of infected health-care providers.

2020 ◽  
Author(s):  
Tahereh Toulabi ◽  
Atefeh Veiskramian ◽  
Abas Azadi ◽  
Heshmatolah Heydari
Keyword(s):  
Health Care ◽  
Health Care Providers ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Phone Call ◽  
Care Providers ◽  
Purposeful Sampling ◽  
Content Analysis Method ◽  
Conventional Content Analysis ◽  
Specific Disorders

Abstract BackgroundCovid-19 is a novel disease with many unknown clinical and managemental dimensions. To effectively diagnose, control, and treat the disease, it is required to divulge its clinical symptoms and their qualities. On the other hand, no one can better interpret the clinical symptoms than the caregivers infected by the disease. So, the aim of this study was to exploring the experiences of infected health-care providers about clinical manifestations of Covid-19 disease.MethodsThe present qualitative research was conducted using the conventional content analysis method in Iran from March to Jun 2020. Participants in this study included infected health care providers with Covid-19, who were selected based on purposeful sampling method. The data was collected by 18 phone call interviews and analyzed according Lundman and Graneheim approach.ResultsQualitative data analysis revealed 10 categories including respiratory disorders, fever and chills, body pain, fatigue, headache, skin disorders, gastrointestinal disorders, taste and olfactory disturbances, insomnia and also stress and anxiety.ConclusionPatients with Covid-19 may experience specific or non-specific disorders. It is necessary to consider people with non-specific manifestations as suspicious cases and screen them with proper diagnostic tests. This can help to identify true positive patients and provide them with more effective health cares, and prevent further spread of the disease by isolating suspected individuals.Trial registration numberNot applicable

scholarly journals Current status of traditional Chinese medicine for the treatment of COVID-19 in China

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Liang Chu ◽  
Fang Huang ◽  
Mengdan Zhang ◽  
Biao Huang ◽  
Yigang Wang
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Symptoms ◽  
Influenza Pandemic ◽  
Clinical Manifestations ◽  
Direct Determination ◽  
Respiratory Illness ◽  
Nucleic Acid Amplification ◽  
Current Status ◽  
Respiratory Coronavirus

AbstractAn ongoing outbreak of severe respiratory illness and pneumonia caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2) commenced in December 2019, and the disease was named as coronavirus disease 2019 (COVID-19). Soon after, scientists identified the characteristics of SARS-CoV-2, including its genome sequence and protein structure. The clinical manifestations of COVID-19 have now been established; and nucleic acid amplification is used for the direct determination of the virus, whereas immunoassays can determine the antibodies against SARS-CoV-2. Clinical trials of several antiviral drugs are ongoing. However, there is still no specific drugs to treat COVID-19. Traditional Chinese medicine (TCM) was used in the treatment of COVID-19 during the early stages of the outbreak in China. Some ancient TCM prescriptions, which were efficacious in the treatment of severe acute respiratory syndrome (SARS) in 2002–03 and the influenza pandemic (H1N1) of 2009, have been improved by experienced TCM practitioners for the treatment of COVID-19 based on their clinical symptoms. These developed new prescriptions include Lianhua Qingwen capsules/granules, Jinhua Qinggan granules and XueBiJing injection, among others. In this review, we have summarized the presenting features of SARS-CoV-2, the clinical characteristics of COVID-19, and the progress in the treatment of COVID-19 using TCMs.

scholarly journals Mano-Impedancemetric Diagnosis of Esophageal Function in Children With Dyspepsia

2018 ◽  
Vol 15 (5) ◽  
pp. 402-409
Author(s):  
Marina Ju. Stepanyan ◽  
Elena V. Komarova ◽  
Maksim M. Lohmatov
Keyword(s):  
Gastrointestinal Tract ◽  
Esophageal Motility ◽  
Clinical Manifestations ◽  
Distal Esophagus ◽  
Upper Gastrointestinal Tract ◽  
Functional Disorders ◽  
Esophageal Function ◽  
Long Time ◽  
Upper Gastrointestinal ◽  
Selection Of

Background. Introduction of new methods of diagnosing functional disorders of the upper gastrointestinal tract into children’s practice will reveal the true cause of changes in esophageal motility in its various pathologies, which will significantly change the treatment tactics, since the selection of therapy will be based on the pathogenetic mechanisms of disease development.Our aim was to highlight the capabilities and benefits of high-resolution mano-impedancemetry in comparison with esophagogastroduodenoscopy, which has been studied and used in pediatric practice for a long time, and to prove that only due to a new method for diagnosing esophageal motility disorders, it is possible to determine the cause of dyspeptic complaints in children.Patients and Methods. The results of our own examination of children aged from 7 to 17 years 11 months (n = 23) with clinical manifestations of functional disorders of the upper gastrointestinal tract have been presented.Results. According to the mano-impedancemetry data, it has been found that the time of the substrate in the esophagus (p<0.02) and the speed of its passage through the esophagus depend on the pressure in the distal esophagus: the lower the pressure in the distal esophagus, the lower the fluid flow rate and the higher the degree of its reflux (р<0.001). Decreased speed indicates hypotonia of the lower esophagus and lower esophageal sphincter, which provides only a correction by physiotherapeutic treatment methods since surgical intervention in such conditions is ineffective.Conclusion. The method of mano-impedancemetry allows to determine the indications for surgical treatment and to predict the efficacy of the conducted anti-reflux surgical correction.

scholarly journals Frequency of involvement different parts of the gastrointestinal tract in the pathological process in children with biliary dysfunction

2021 ◽  
pp. 24-28
Author(s):  
T.V. Sorokman ◽  
◽  
L.Yu. Khlunovska ◽  
I.Ya. Lozyuk ◽  
◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Chronic Gastritis ◽  
Clinical Symptoms ◽  
Duodenogastric Reflux ◽  
Pathological Process ◽  
Functional Disorders ◽  
Significance Level ◽  
Intestinal Involvement ◽  
Instrumental Methods ◽  
The Relationship

The close anatomical and physiological connection of the digestive organs leads to a significant spread of functional disorders in various diseases. Purpose — to investigate the frequency and features of the clinical course of biliary dysfunction (BD) in children. Materials and methods. 66 children aged 10–18 years with BD were examined. The study included a complete clinical examination of children, laboratory and instrumental methods. To assess the severity of clinical symptoms in the examined patients was used traditional score scale of symptoms (0–3 points) and the frequency index (FI). Results. In most children, the database was combined with other functional and organic lesions of the digestive tract (n=56, 84.8%). The database was most often combined with chronic gastritis and duodenitis, as well as with functional motor disorders. FI in children with BD involved in the pathological process of the stomach and duodenum was the highest (0.59), and IR in children with BD and intestinal involvement was the lowest (0.23). The relationship between the frequency of combined pathology and the frequency of cases of increase in the size of the gallbladder (χ2=22.87 at a critical value of χ2=9.33 for the significance level p<0.01). Hyper- or hypofunctions of the biliary tract occurred with the same frequency. Conclusions. Biliary dysfunction in children is significantly more often combined with chronic gastritis and duodenitis, as well as with other functional disorders of the gastrointestinal tract (duodenogastric reflux). In children with biliary dysfunction and involvement in the pathological process of other parts of the gastrointestinal tract there is an increase in the frequency of exacerbations, more pronounced signs of dyspeptic syndrome on the background of pain with the same intensity and more often ultrasound reveals signs of gallbladder dysformation. The research was carried out in accordance with the principles of the Helsinki declaration. The study protocol was approved by the Local Ethics Committee of all participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the authors. Key words: children, biliary dysfunction.

scholarly journals DUPLICATION OF THE GASTROINTESTINAL TRACT IN CHILDREN

2018 ◽  
Vol 22 (6) ◽  
pp. 309-316
Author(s):  
A. N. Smirnov ◽  
Nadezhda V. Gavrilenko
Keyword(s):  
Surgical Treatment ◽  
Gastrointestinal Tract ◽  
Digestive Tract ◽  
Blood Supply ◽  
Clinical Symptoms ◽  
Smooth Muscles ◽  
Developmental Defect ◽  
Digestive Tube ◽  
Ectopic Tissue ◽  
Rare Malformation

Duplication of the gastrointestinal tract (GIT) being a rare malformation can be localized in anywhere of the digestive tube. The incidence of this disease is 1:4,500 newborns. In most cases doubling of the gastrointestinal tract is diagnosed before the age of two years and is found in both girls and boys with a slight predominance of boys. Duplications of the gastrointestinal tract are closely connected cystic or tubular structures possessing a common blood supply with any part of the digestive tract. Signs of doubling are a well-developed layer of smooth muscles in the wall of duplication and the presence of the mucous membrane. The type of mucosa of the formation generally corresponds to the gastrointestinal tract from which it originates but in 29-35% of cases ectopic tissue occurs. The spectrum of clinical symptoms of gastrointestinal redundancies is extremely diverse and often the diagnosis of the disease presents great difficulties for the surgeon. It depends on the type of duplication, location, size, the presence of ectopic mucosa and communication with the lumen of a healthy area of the digestive tract. At present, there is no consensus on the tactics of managing patients with GITduplication. The choice of the method of surgical treatment (enucleation, fenestration, resection) is determined by the following criteria: the localization and size of pathological formation, the mobility of the supporting segment of the digestive tube, the ratio to the lumen segment of the gastrointestinal tract (extra-, intraluminal position), the type of blood supply, the presence or absence of communication with the lumen of a healthy site of the gastrointestinal tract and the age of the patient. In each case of doubling, an individual approach and choice of tactics for surgical treatment are required. This article presents a literature review on the topic “Doubling the digestive tract in children” in details, there are highlighted theories of embryogenesis of this developmental defect, classifications, clinical features, diagnosis and surgical treatment of duplications of different localization.

scholarly journals Clinical Manifestations of Covid-19 Disease; Exploring the Experiences of Infected Health-Care Providers.

2020 ◽  
Author(s):  
Tahereh Toulabi ◽  
Atefeh Veiskramian ◽  
Abas Azadi ◽  
Heshmatolah Heydari
Keyword(s):  
Health Care ◽  
Health Care Providers ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Phone Call ◽  
Care Providers ◽  
Purposeful Sampling ◽  
Content Analysis Method ◽  
Registration Number ◽  
Specific Disorders

Abstract Background: Covid-19 is a novel disease with many unknown clinical and managemental dimensions. To effectively diagnose, control, and treat the disease, it is required to divulge its clinical symptoms and their qualities. On the other hand, no one can better interpret the clinical symptoms than the caregivers infected by the disease. So, the aim of this study was to exploring the experiences of infected health-care providers about clinical manifestations of Covid-19 disease.Methods: The present qualitative research was conducted using the conventional content analysis method in Iran from March to Jun 2020. Participants in this study included infected health care providers with Covid-19, who were selected based on purposeful sampling method. The data was collected by 18 phone call interviews and analyzed according Lundman and Graneheim approach.Results: Qualitative data analysis revealed 10 categories including respiratory disorders, fever and chills, body pain, fatigue, headache, skin disorders, gastrointestinal disorders, taste and olfactory disturbances, insomnia and also stress and anxiety.Conclusion: Patients with Covid-19 may experience specific or non-specific disorders. It is necessary to consider people with non-specific manifestations as suspicious cases and screen them with proper diagnostic tests. This can help to identify true positive patients and provide them with more effective health cares, and prevent further spread of the disease by isolating suspected individuals.Trial registration number: Not applicable

Etiology and clinical features of epididymo-orchitis: A single-center study in Tehran, Iran

2020 ◽  
Vol 20 ◽  
Author(s):  
Sara Abolghasemi ◽  
Mohammad Alizadeh ◽  
Ali Hashemi ◽  
Shabnam Tehrani
Keyword(s):  
Chlamydia Trachomatis ◽  
Clinical Symptoms ◽  
Urine Culture ◽  
Clinical Manifestations ◽  
Urinary Frequency ◽  
Serological Tests ◽  
Duration Of Symptoms ◽  
Two Samples ◽  
History Of ◽  
Tract Infections

Introduction: Epididymo-orchitis is a common urological disease among men. Little is known about the clinical and epidemiological aspects of the disease in Iran. Thus, the present study was aimed to investigate the etiology, clinical sequelae and risk factors of patients with epididymo-orchitis in Tehran, Iran. Materials and Methods: Patients presenting with epididymo-orchitis were prospectively analyzed in order to study the etiology and pattern of the disease. Bacteriological, molecular and serological tests were undertaken to look for Chlamydia trachomatis, Neisseria gonorrhoeae, Brucella spp., Mycoplasma spp, and other bacteria. Results: Fifty patients with epididymo-orchitis were evaluated according to their clinical symptoms, duration of symptoms, physical examination, and laboratory studies. The mean age of the patients was 53 years. Fever, dysuria, pain in the flanks, urinary frequency and discharges occurred in 58.0%, 50.0%, 50.0%, 28.0% and 6.0%, respectively. Bacterial pathogen was identified in 26% (13/50) of patients by urine culture. Escherichia coli was the etiological agent in 11/13 patients (84.6%). Two out of 50 patients (4.0%) were also positive for Chlamydia trachomatis. Two samples were serologically positive for Brucella spp. High Mean age, fever, urinary frequency, history of the underlying disease and history of urinary tract infections were found to have a significant association with the positive bacteriologic urine culture (P<0.05). Conclusions: The most common clinical manifestations were fever, dysuria, and abdominal pain. E. coli and C. trachomatis were the major causative agents. Use of a set of diagnostic approaches including clinical symptoms, urine culture and more precise techniques such as PCR should be taken into consideration for the definitive diagnosis.

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