scholarly journals Current status of traditional Chinese medicine for the treatment of COVID-19 in China

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Liang Chu ◽  
Fang Huang ◽  
Mengdan Zhang ◽  
Biao Huang ◽  
Yigang Wang
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Symptoms ◽  
Influenza Pandemic ◽  
Clinical Manifestations ◽  
Direct Determination ◽  
Respiratory Illness ◽  
Nucleic Acid Amplification ◽  
Current Status ◽  
Respiratory Coronavirus

AbstractAn ongoing outbreak of severe respiratory illness and pneumonia caused by the severe acute respiratory coronavirus 2 (SARS-CoV-2) commenced in December 2019, and the disease was named as coronavirus disease 2019 (COVID-19). Soon after, scientists identified the characteristics of SARS-CoV-2, including its genome sequence and protein structure. The clinical manifestations of COVID-19 have now been established; and nucleic acid amplification is used for the direct determination of the virus, whereas immunoassays can determine the antibodies against SARS-CoV-2. Clinical trials of several antiviral drugs are ongoing. However, there is still no specific drugs to treat COVID-19. Traditional Chinese medicine (TCM) was used in the treatment of COVID-19 during the early stages of the outbreak in China. Some ancient TCM prescriptions, which were efficacious in the treatment of severe acute respiratory syndrome (SARS) in 2002–03 and the influenza pandemic (H1N1) of 2009, have been improved by experienced TCM practitioners for the treatment of COVID-19 based on their clinical symptoms. These developed new prescriptions include Lianhua Qingwen capsules/granules, Jinhua Qinggan granules and XueBiJing injection, among others. In this review, we have summarized the presenting features of SARS-CoV-2, the clinical characteristics of COVID-19, and the progress in the treatment of COVID-19 using TCMs.

scholarly journals Insights from the Perspective of Traditional Chinese Medicine to Elucidate Association of Lily Disease and Yin Deficiency and Internal Heat of Depression

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Bingxian Shang ◽  
Hongxiu Zhang ◽  
Yanting Lu ◽  
Xiaoyu Zhou ◽  
Yong Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Internal Heat ◽  
Psychological Problems ◽  
Yin Deficiency ◽  
Zhang Zhongjing ◽  
New Ideas ◽  
The Relationship

Lily disease was first recorded in Synopsis of the Golden Chamber by Zhang Zhongjing. It is a disease of heart and lung internal heat by Yin deficiency, which belongs to the category of emotion disease in Chinese medicine. In recent years, researchers believe that lily disease and depression syndrome of Yin deficiency and internal heat have many similarities in etiology, pathogenesis, and clinical manifestations. This review summarizes the clinical symptoms, etiology, pathogenesis, and therapeutic medication of lily disease and modern Yin-deficient internal heat depression and discusses the relationship between them. Furthermore, the relationship between coronavirus disease 2019 (COVID-19) and lily disease was discussed from the etiology, pathogenesis, and treatment. It provides new ideas for the treatment of COVID-19 and the treatment of psychological problems after recovery.

scholarly journals Fever and Antipyretic Supported by Traditional Chinese Medicine: A Multi-Pathway Regulation

2021 ◽  
Vol 12 ◽  
Author(s):  
Le-Le Ma ◽  
Hui-Min Liu ◽  
Chuan-Hong Luo ◽  
Ya-Nan He ◽  
Fang Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Symptoms ◽  
Signal Transmission ◽  
Public Health Problem ◽  
Pharmacological Action ◽  
Major Public Health Problem ◽  
Neural Pathways ◽  
The World ◽  
In Series

The coronavirus disease, 2019 (COVID-19), has spread rapidly around the world and become a major public health problem facing the world. Traditional Chinese medicine (TCM) has been fully committed to treat COVID-19 in China. It improved the clinical symptoms of patients and reduced the mortality rate. In light of the fever was identified as one of leading clinical features of COVID-19, this paper will first analyze the material basis of fever, including pyrogenic cytokines and a variety of the mediators of fever. Then the humoral and neural pathways of fever signal transmission will be described. The scattered evidences about fever recorded in recent years are connected in series. On this basis, the understanding of fever is further deepened from the aspects of pathology and physiology. Finally, combining with the chemical composition and pharmacological action of available TCM, we analyzed the mechanisms of TCMs to play the antipyretic effect through multiple ways. So as to further provide the basis for the research of antipyretic compound preparations of TCMs and explore the potential medicines for the prevention and treatment of COVID-19.

scholarly journals Functional diseases of the gastrointestinal tract in the context with overlapping functional disorders: current status of the problem

2020 ◽  
Vol 92 (2) ◽  
pp. 111-118
Author(s):  
M. A. Osadchuk ◽  
A. A. Svistunov ◽  
N. V. Kireeva ◽  
M. M. Osadchuk
Keyword(s):  
Health Care ◽  
Gastrointestinal Tract ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Current Status ◽  
Functional Disorders ◽  
Digestive Tube ◽  
Psychosocial Disorders ◽  
Significant Damage ◽  
Course Features

Functional diseases of the gastrointestinal tract cause significant damage to the health care system. Their frequent combination in the same patient with the migration of clinical symptoms throughout the digestive tube is accompanied by continuous exacerbations, refractory to the therapy and severe psychosocial disorders. This review provides data on the main etiopathogenetic factors, clinical manifestations, course features and management tactics for patients with overlapping for the most common functional diseases of the gastrointestinal tract.

scholarly journals Imaging Diagnosis of Transient Ischemic Attack in Clinic and Traditional Chinese Medicine

2019 ◽  
Vol 2019 ◽  
pp. 1-10
Author(s):  
Qigu Yao ◽  
Lincheng Zhang ◽  
Jing Zhou ◽  
Min Li ◽  
Weifeng Jing ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Transient Ischemic Attack ◽  
Doppler Sonography ◽  
Clinical Symptoms ◽  
Transcranial Doppler Sonography ◽  
Imaging Modalities ◽  
Ischemic Attack ◽  
And Function ◽  
Ct And Mri

Neuroimaging plays a pivotal role in Transient Ischemic Attack (TIA). Generally, clinicians focus on the specific changes in morphology and function, but the diagnosis of TIA often depends on imaging evidence. Whereas Traditional Chinese Medicine (TCM) is concerned with the performance of clinical symptoms, they began to use imaging methods to diagnose TIA. CT and MRI are the recommended modality to diagnose TIA and image ischemic lesions. In addition, Transcranial Doppler sonography (TCD) and Digital Subtraction Angiography (DSA) are two acceptable alternatives for diagnosing TIA patients. This article elaborates the update of imaging modalities in clinic and the development of imaging modalities in TCM. Besides, multiple joint imaging technologies also will be evaluated whether enhanced diagnostic yields availably.

scholarly journals The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting

2020 ◽  
Vol 17 (16) ◽  
pp. 5648 ◽  
Author(s):  
Hossein Hozhabri ◽  
Francesca Piceci Sparascio ◽  
Hamidreza Sohrabi ◽  
Leila Mousavifar ◽  
René Roy ◽  
...  
Keyword(s):  
Clinical Manifestations ◽  
Weather Conditions ◽  
Respiratory Illness ◽  
Health Concern ◽  
Current Status ◽  
Global Public Health ◽  
Infected People ◽  
Published Evidence ◽  
Human Coronaviruses ◽  
Novel Coronavirus

Over the past two decades, there have been two major outbreaks where the crossover of animal Betacoronaviruses to humans has resulted in severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). In December 2019, a global public health concern started with the emergence of a new strain of coronavirus (SARS-CoV-2 or 2019 novel coronavirus, 2019-nCoV) which has rapidly spread all over the world from its origin in Wuhan, China. SARS-CoV-2 belongs to the Betacoronavirus genus, which includes human SARS-CoV, MERS and two other human coronaviruses (HCoVs), HCoV-OC43 and HCoV-HKU1. The fatality rate of SARS-CoV-2 is lower than the two previous coronavirus epidemics, but it is faster spreading and the large number of infected people with severe viral pneumonia and respiratory illness, showed SARS-CoV-2 to be highly contagious. Based on the current published evidence, herein we summarize the origin, genetics, epidemiology, clinical manifestations, preventions, diagnosis and up to date treatments of SARS-CoV-2 infections in comparison with those caused by SARS-CoV and MERS-CoV. Moreover, the possible impact of weather conditions on the transmission of SARS-CoV-2 is also discussed. Therefore, the aim of the present review is to reconsider the two previous pandemics and provide a reference for future studies as well as therapeutic approaches.

scholarly journals Management of Hepatic Encephalopathy by Traditional Chinese Medicine

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Chun Yao ◽  
Nong Tang ◽  
Guoxiang Xie ◽  
Xiaojiao Zheng ◽  
Ping Liu ◽  
...  
Keyword(s):  
Nervous System ◽  
Hepatic Encephalopathy ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Liver Dysfunction ◽  
Clinical Manifestations ◽  
Modern Medicine ◽  
Future Perspective ◽  
Therapeutic Approaches ◽  
Complex Mechanisms

In spite of the impressive progress in the investigation of hepatic encephalopathy (HE), the complex mechanisms underlying the onset and deterioration of HE are still not fully understood. Currently, none of the existing theories provide conclusive explanations on the symptoms that link liver dysfunction to nervous system disorders and clinical manifestations. This paper summarized the diagnostic and therapeutic approaches used for HE in modern medicine and traditional Chinese medicine and provided future perspective in HE therapies from the viewpoint of holistic and personalized Chinese medicine.

scholarly journals Why Traditional Chinese Medicine can not be a new approach to alleviate the symptoms of COVID-19 ?

2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Geer Chen ◽  
Yehao Luo ◽  
Donghan Xu ◽  
Yuzhou Pang ◽  
Peiqi Ou ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Essential Role ◽  
Clinical Symptoms ◽  
New Approach ◽  
Cough Headache ◽  
Herbal Decoction ◽  
Difficulty Breathing ◽  
Severe Type

Traditional Chinese Medicine (TCM) has a unique set of therapeutic methods for plagues. COVID-19 is a severe type of pneumonia caused by a new coronavirus, which manifests in fever, cough, headache, fatigue, difficulty breathing, and other symptoms. TCM has fully displayed its advantages of various approaches in this epidemic, including herbal decoction, patent herbs, aroma packets, acupuncture, massage, etc. These methods have played an essential role in the prevention, treatment, and nursing of COVID-19, not only in alleviating the early clinical symptoms of patients but reducing the progression from mild to severe symptoms. Thanks to the advantages of treating the pandemic, we should pay more attention to TCM modalities.

scholarly journals Traditional Chinese medicine Lingguizhugan decoction treating non-alcoholic fatty liver disease with spleen-yang deficiency pattern: Study protocol for a multicenter randomized controlled trial

2020 ◽  
Author(s):  
Jing-juan Xu ◽  
Rui-rui Wang ◽  
Sheng-fu You ◽  
Lei Zhang ◽  
Pei-yong Zheng ◽  
...  
Keyword(s):  
Liver Disease ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Liver Function ◽  
Fatty Liver ◽  
Fatty Liver Disease ◽  
Clinical Symptoms ◽  
Efficacy And Safety ◽  
Alcoholic Fatty Liver ◽  
Alcoholic Fatty Liver Disease

Abstract Background Nonalcoholic fatty liver disease (NAFLD) is a metabolic stress liver injury induced by excessive fat accumulation in liver, which is closely related to insulin resistance (IR). Traditional Chinese medicine (TCM) has showed good curative effects and unique advantages in the prevention and treatment of NADLD, particularly in improving IR, liver function and clinical symptoms. This study will examine the efficacy and safety of Lingguizhugan decoction (LGZG) in the treatment of non-alcoholic fatty liver disease with spleen-yang deficiency pattern, and assess the optimal dosage. Methods/design This study is a three-arm, dose-optimization, randomized, double-blinded, placebo-controlled clinical trial. A total of 243 NAFLD patients will be recruited and randomly assigned to standard dose Lingguizhugan decoction (SLGD) group, low dose Lingguizhugan decoction (LLGD) group, or the control group. The clinical indicator will be assessed during the 12-week intervention and follow-up 4 weeks. The primary outcome is the percentage of patients whose the decline of HOMA-IR reaches one standard unit. Secondary outcomes include body weight, body mass index, liver function, blood lipid metabolism, blood glucose metabolism, liver-kidney echo ratio, quantitative rating of clinical symptoms and signs, collecting sample(s) from participants, the medical outcomes study(MOS) item short from health survey(SF-36), Self-rating Depressive Scale(SAS), and Self-rating Anxiety Scale(SDS). Discussion This study will provide initial evidence regarding the efficacy and safety of LGZG in the treatment of NAFLD with spleen-yang deficiency pattern, meanwhile establish the demonstration technique, and promote its application in community healthcare center. In addition, potential mechanism will be explored based on research of oral and gut microbiota.

scholarly journals Syndrome Differentiation and Treatment Regularity in Traditional Chinese Medicine for Type 2 Diabetes: A Text Mining Analysis

2021 ◽  
Vol 12 ◽  
Author(s):  
Zhili Dou ◽  
Ye Xia ◽  
Jiawei Zhang ◽  
Yizhen Li ◽  
Yunan Zhang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Current Status ◽  
Syndrome Differentiation ◽  
Acupuncture Points ◽  
Acupoint Therapy ◽  
Clinical Databases ◽  
Tcm Syndrome

ObjectiveThe goal of this study was to systematically summarize and categorize the syndrome differentiation, medication rules, and acupoint therapy in the domestic traditional Chinese medicine (TCM) literature on type 2 diabetes mellitus (T2DM), such that guidelines and new insights can be provided for future practitioners and researchers.MethodsTaking randomized controlled trials (RCTs) on the treatment of T2DM in TCM as the research theme, we searched for full-text literature in three major clinical databases, including CNKI, Wan Fang, and VIP, published between 1990 and 2020. We then conducted frequency statistics, cluster analysis, association rules extraction, and topic modeling based on a corpus of medical academic words extracted from 3,654 research articles.ResultsThe TCM syndrome types, subjective symptoms, objective indicators, Chinese herbal medicine, acupuncture points, and TCM prescriptions for T2DM were compiled based on invigorating the kidney and Qi, nourishing Yin, and strengthening the spleen. Most TCM syndrome differentiation for T2DM was identified as “Zhongxiao” (the lesion in the spleen and stomach) and “Xiaxiao” (the lesion in the kidney) deficiency syndromes, and most medications and acupoint therapies were focused on the “Spleen Channel” and “Kidney Channel.” However, stagnation of liver Qi was mentioned less when compared with other syndromes, which did not have symptomatic medicines.ConclusionThis study provides an in-depth perspective for the TCM syndrome differentiation, medication rules, and acupoint therapy for T2DM and provides practitioners and researchers with valuable information about the current status and frontier trends of TCM research on T2DM in terms of both diagnosis and treatment.

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