scholarly journals Primary lymphangiectasia of the gastrointestinal tract

2018 ◽  
Vol 90 (3) ◽  
pp. 96-98
Author(s):  
E M Esedov ◽  
A S Abasova ◽  
F D Akhmedova ◽  
L N Musaeva
Keyword(s):  
Trace Elements ◽  
Gastrointestinal Tract ◽  
Lymphatic Vessels ◽  
Intestinal Wall ◽  
Symptomatic Therapy ◽  
Intestinal Lymphangiectasia ◽  
Medium Chain Triglycerides ◽  
Medicinal Foods ◽  
Instrumental Methods ◽  
Test Treatment

Intestinal lymphangiectasia is a very rare pathology, characterized by the presence of enlarged lymphatic vessels in all layers of the intestinal wall and in the mesentery. As a result, "lymphatic lakes" are formed, through which lymph exudates into the lumen of the intestine. The main manifestation is hypoproteinemic edema. Diagnosis of the disease is based on laboratory-instrumental methods of investigation, including by determining in the stool α-1 antitrypsin as a screening test. Treatment includes: a diet rich in calcium, trace elements, be sure to use medicinal foods enriched with medium chain triglycerides, substitution and symptomatic therapy.

scholarly journals Congenital intestinal lymphangiectasia

2011 ◽  
Vol 68 (3) ◽  
pp. 270-273
Author(s):  
Dusan Popovic ◽  
Milan Spuran ◽  
Tamara Alempijevic ◽  
Miodrag Krstic ◽  
Srdjan Djuranovic ◽  
...  
Keyword(s):  
Early Recognition ◽  
Clinical Manifestations ◽  
Lymphatic Vessels ◽  
High Protein Diet ◽  
Intestinal Wall ◽  
Intestinal Biopsy ◽  
Intestinal Lymphangiectasia ◽  
Laboratory Assessment ◽  
Protein Losing Enteropathy ◽  
Adequate Treatment

Background. Congenital intestinal lymphangiectasia is a disease which leads to protein losing enteropathy. Tortous, dilated lymphatic vessels in the intestinal wall and mesenterium are typical features of the disease. Clinical manifestations include malabsorption, diarrhea, steatorrhea, edema and effusions. Specific diet and medication are required for disease control. Case report. A 19-year old male patient was hospitalized due to diarrhea, abdominal swelling, weariness and fatigue. Physical examination revealed growth impairment, ascites, and lymphedema of the right hand and forearm. Laboratory assessment indicated iron deficiency anaemia, lymphopenia, malabsorption, inflammatory syndrome, and urinary infection. Enteroscopy and video capsule endoscopy demonstrated dilated lymphatic vessels in the small intestine. The diagnosis was confirmed by intestinal biopsy. The patient was put on high-protein diet containing medium-chain fatty acids, somatotropin and suportive therapy. Conclusion. Congenital intestinal lymphangiectasia is a rare disease, usually diagnosed in childhood. Early recognition of the disease and adequate treatment can prevent development of various complications.

scholarly journals Primary intestinal lymphangiectasia in a 23-month- old girl

2019 ◽  
Vol 2019 (7) ◽  
Author(s):  
Lava Mohammad ◽  
Razan Omran ◽  
Alexandr Ibrahim ◽  
Mohammad Adib Hourieh ◽  
Ali Ibrahim
Keyword(s):  
Gastrointestinal Tract ◽  
Gastrointestinal Endoscopy ◽  
High Protein Diet ◽  
Upper Gastrointestinal Endoscopy ◽  
Intestinal Lymphangiectasia ◽  
Medium Chain Triglycerides ◽  
Diet Supplements ◽  
Fat Soluble Vitamins ◽  
Oral Supplements ◽  
Upper Gastrointestinal

Abstract Primary intestinal lymphangiectasia (PIL) is a rare protein-losing gastroenteropathy which is defined as dilation of existing mucosal, submucosal, or subserosal lymphatics within the gastrointestinal tract. That causes loss of lymph fluid into the gastrointestinal tract, leading to the development of hypoproteinemia, edema, lymphocytopenia, hypogammaglobinemia, and immunologic anomalies. It is usually diagnosed in patients younger than 3 years old and is rarely first diagnosed in adulthood. Here we have a case report in a 23-month- old female presented with the complaint of peripheral edema and diarrhea. The diagnosis of PIL was made through upper gastrointestinal endoscopy and pathology histologic analysis. Patient placed on oral supplements of medium-chain triglycerides, a high protein diet, supplements of fat-soluble vitamins and responded well.

scholarly journals Canine Intestinal Lymphangiectasia Concomitant with Renal Cell Carcinoma

2021 ◽  
Vol 71 (3) ◽  
pp. 351-360
Author(s):  
Eun-Joo Lee ◽  
Myung-Jin Chung ◽  
Kyu-Shik Jeong
Keyword(s):  
Renal Cell Carcinoma ◽  
Gastrointestinal Tract ◽  
Cell Carcinoma ◽  
Renal Cell ◽  
Rare Case ◽  
Lymphatic Vessels ◽  
Gastrointestinal Neoplasms ◽  
Intestinal Lymphangiectasia ◽  
Abdominal Neoplasm ◽  
Cisterna Chyli

Abstract The etiology of dilation of lymphatic vessels, termed as intestinal lymphangiectasia, remains unknown. In most cases, it occurs secondary to other pathologic conditions such as gastrointestinal neoplasms. However, only a few cases of canine intestinal lymphangiectasia concurrent with non-gastrointestinal neoplasms have been reported so far. Moreover, the correlation between intestinal lymphangiectasia and non-gastrointestinal neoplasms has not been discussed in any other literature. In this study, we report a rare case of intestinal lymphangiectasia concomitant with renal cell carcinoma in an 11 year old female mixed Maltese, suggesting that non-gastrointestinal neoplasms could be associated with the development of intestinal lymphangiectasia. On gross observation, the small intestine was irregularly swollen presenting an accordion like shape. Microscopic examination revealed prominent dilatation of the lymphatic vessels, especially, within the submucosa and muscularis layer. The lacteals within the villi were dilated and presented “club-shaped” tips. The carcinoma might trigger intestinal lymphangiectasia by compressing the main lymphatic vessels or the cisterna chyli, subsequently increasing the pressure of the lymphatic vessels in the gastrointestinal tract. Moreover, metastasis of the carcinoma to the gastrointestinal tract could induce intestinal lymphangiectasia. Thus, the occurrence of intestinal lymphangiectasia must be considered when an abdominal neoplasm is located around major lymphatic vessels.

scholarly journals Gastrointestinal Cryptococcosis Associated with Intestinal Lymphangiectasia

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Fernando Naranjo-Saltos ◽  
Alejandro Hallo ◽  
Carlos Hallo ◽  
Andres Mayancela ◽  
Alejandra Rojas
Keyword(s):  
Opportunistic Infections ◽  
Lymphatic Vessels ◽  
Immunocompetent Patient ◽  
Intestinal Lumen ◽  
Histopathological Study ◽  
Intestinal Lymphangiectasia ◽  
Protein Losing Enteropathy ◽  
Unusual Association ◽  
Intestinal Involvement ◽  
Cellular Components

Intestinal lymphangiectasia is a pathological dilation of enteric lymphatic vessels resulting in lymph leakage to the intestinal lumen. This chronic lymph leakage leads to a state of immunosuppression secondary to the loss of humoral and cellular components of the immune system and represents a potential risk factor for opportunistic infections. We report a case of protein-losing enteropathy in a seemingly immunocompetent patient. An intestinal histopathological study revealed the unusual association of lymphangiectasia and intestinal cryptococcosis. Although cryptococcal infection is common in immunocompromised patients, intestinal involvement is rarely reported. We found no reports on the association of intestinal cryptococcosis in patients with lymphangiectasia. This case report is the first to describe intestinal cryptococcosis associated with intestinal lymphangiectasia.

Lymphatics in the Alimentary Tract of Children in Health and Disease: Study on Mucosal Biopsies Using the Monoclonal Antibody D2-40

2005 ◽  
Vol 8 (5) ◽  
pp. 541-549 ◽  
Author(s):  
Yiping Zeng ◽  
Fenghua Wang ◽  
Elizabeth D. Williams ◽  
Chung Wo Chow
Keyword(s):  
Clinical Features ◽  
Alimentary Tract ◽  
Lymphatic Vessels ◽  
Specific Method ◽  
Intestinal Lymphangiectasia ◽  
Histologic Diagnosis ◽  
Protein Losing Enteropathy ◽  
Negative Finding ◽  
Young Infants ◽  
Disease Study

Primary intestinal lymphangiectasia and intestinal lymphatic hypoplasia are 2 causes of protein-losing enteropathy in children and share many common clinical features. For the diagnosis of lymphatic hypoplasia on endoscopic biopsies of the intestine, i.e., based on a negative finding in a small specimen, a very sensitive and specific method for identifying lymphatics is essential. In the present study, lymphatic vessels were labelled using D2-40 immunostaining in mucosal biopsy specimens of the alimentary tract of children in whom no histologic abnormality was noted and of those who had different relatively common pediatric conditions, including inflammatory and neoplastic diseases. Using this method, lymphatic vessels were well visualized even in young infants and not destroyed by diseases. The presence of the muscularis mucosae in specimens was important for adequate assessment. In the duodenum and esophagus, lymphatics were observed in every single section; in the stomach, ileum, and colon, they were less regular and several sections were sometimes required. The extreme sensitivity of this method for demonstrating lymphatic vessels in the duodenum makes it ideal for the histologic diagnosis of intestinal lymphatic hypoplasia. In 4 patients who were considered to have this diagnosis based on clinical features, full-thickness intestinal biopsies and electron microscopy, D2-40 immunostaining confirmed the absence or marked paucity of lymphatics.

scholarly journals First clinical experiences with a novel endoscopic over-the-scope clip system

2017 ◽  
Vol 05 (03) ◽  
pp. E151-E156 ◽  
Author(s):  
Marco Dinelli ◽  
Barbara Omazzi ◽  
Paolo Andreozzi ◽  
Nicola Zucchini ◽  
Alessandro Redaelli ◽  
...  
Keyword(s):  
Gastrointestinal Tract ◽  
Clinical Success ◽  
Endocrine Tumor ◽  
Intestinal Wall ◽  
R0 Resection ◽  
The Novel ◽  
Clinical Experiences ◽  
Endoscopic Full Thickness Resection ◽  
Over The Scope Clip ◽  
Otsc System

AbstractWe describe our experience with a new over-the-scope clip (OTSC) system (Padlock Clip™) in the treatment of 14 patients. Eight of the 14 patients were treated for closure of gastrointestinal fistulas (n = 4), iatrogenic gastrointestinal perforations (n = 2), or hemostasis of post-polypectomy bleeding (n = 2). The site of clipping was the lower gastrointestinal tract in five patients and the upper gastrointestinal tract in three patients. The clip was successfully delivered in seven out of the eight patients and clinical success was achieved in all patients. Endoscopic full thickness resection (EFTR) was performed to treat six patients: four with recurrent adenoma (n = 4), one with ulcerated nodules at ileorectal anastomosis, and one with a neuro-endocrine tumor of the rectum. A complete intestinal wall resection was achieved in three of the six patients (50 %) and an R0 resection in five of the six patients (83.3 %). No complications related to the procedure and no recurrence at endoscopic follow-up were observed in any patient. The novel Padlock Clip seems to be an effective and safe tool to treat gastrointestinal fistulas, perforations or post-polypectomy bleeding, and to perform EFTR.

scholarly journals POSSIBILITIES OF MATHEMATICAL PREDICTION OF ACUTE EROSIVE-ULCERATIVE LESIONS OF UPPER PARTS OF GASTROINTESTINAL TRACT IN PATIENTS WITH SEVERE BURNS

2017 ◽  
Vol 176 (2) ◽  
pp. 51-56
Author(s):  
O. N. Ergashev ◽  
E. N. Zinov’Ev ◽  
Yu. M. Vinogradov
Keyword(s):  
Data Analysis ◽  
Gastrointestinal Tract ◽  
Preventive Measures ◽  
Clinical Laboratory ◽  
Severe Burns ◽  
Effective System ◽  
Ulcerative Lesions ◽  
Instrumental Methods ◽  
High Possibility ◽  
Extensive Burns

OBJECTIVE. The authors created an effective system of prediction of acute erosive-ulcerative lesions of the stomach and duodenum in victims with extensive burns. MATERIALS AND METHODS. The patients (85) were divided into two groups. The first group included 45 patients (53 %) with erosive ulcerative lesions of the stomach and duodenum which developed during 14 days after injury. The second group numbered 40 patients (47 %) without complications. The clinical, laboratory and instrumental methods of investigations were applied. RESULTS. According to data analysis of patient’s examination, the scale of assessment of sign rates was developed. The amount of rates corresponded to the index of prediction (IP). The values of IP were calculated at the interval from -15 to +15 units. The high possibility (85 %) of development of acute erosive and ulcerative lesions of the stomach and duodenum could be expected in cases when IP was about +15 units. CONCLUSIONS. The developed predictive scale of erosive-ulcerative complications of gastrointestinal tract appeared to be highly reliable and allowed doctors to use preventive measures on time.

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