Role of Dermaroller and Prp In Post-Traumatic Facial Scar Treatments

In the present study follow up kept on immediate post-operative day and at one week to evaluate pain, bleeding and inflammation. Final follow up at two months for assessment of aesthetic score by three independent personnel. Pain and inflammation were more associated with Group B compared to Group A, but there are no statistical significance differences among this groups (P value- 0.074 and 0.136 for pain and inflammation respectively on immediate post-operative day. Chi-square test). Final follow up assessment of aesthetic scores at two months calculated by Chi- square test and comparisons of two groups for aesthetic scores done by Independent t-Test. All three personnel gave higher aesthetic score to Group B but statistically this was not significant (P-value 0.287, 0.129 and 0.400 by Observer 1, 2 and patients respectively. Chi-square test). The mean aesthetic score given by Observer 1, 2 and patient was higher associated to Group B but statistically this was not significant (P=0.526, 0.055 and 0.232 independent t-Test).

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Combination Therapy Of Tadalafil And Pentoxifylline In Severe Erectile Dysfunction; A Prospective Randomized Trial

Polish Journal of Surgery ◽

10.1515/pjs-2015-0075 ◽

2015 ◽

Vol 87 (8) ◽

Cited By ~ 2

Author(s):

Santosh Kumar ◽

Rajesh Roat ◽

Swati Agrawal ◽

Kumar Jayant ◽

Ravimohan S. Mavuduru ◽

...

Keyword(s):

Erectile Dysfunction ◽

Combination Therapy ◽

Erectile Function ◽

T Test ◽

P Value ◽

Chi Square ◽

Significant Difference ◽

Chi Square Test ◽

Group A ◽

Group B

Abstractwas to assess efficacy of Tadalafil alone versus Tadalafil plus Pentoxifylline in the treatment of erectile dysfunction by using self administered IIEF-5 questionnaire.Two hundred and thirty seven patients presenting with ED at andrology OPD were evaluated for ED by a self administered IIEF (International Index of Erectile Function) questionnaire. Patients were systematically randomized by computer generated random table into two groups groups namely, group A: Tadalafil only group, group B: combination of Tadalafil + Pentoxifyl-line. All the patients were re-assessed by IIEF-5 questionnaire after 8 weeks of medical therapy. Statistical analysis was performed using student’s unpaired t-test, paired t-test, chi square test. p-value < 0.05 was considered statistically significant.Two hundred and thirty seven patients were included in the present study, in group A: 92 patients (78.6%) showed improvement in their IIEF score after 8 weeks of tadalafil treatment. While in group B, overall 104 patients(86.6%) showed improvement after combination of Tadalafil and Pentoxifylline. There was a statistically significant difference of percentage change in IIEF score was seen in group B (group A 90.7±15.2%, group B 95.6±13.4%; p value – 0.014). We found this difference even more statistically significant in patients with severe ED (group A 72.7±47.2%, group B 132.3±54.3%; p value – 0.000). There was no significant difference in between the two groups with regards to occur-rence of side effects.Both tadalafil and combination of Tadalafil + Pentoxifylline improve erectile function in patients of ED. Patients with severe ED showed much significant improvement in erectile function with combination therapy.

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Incidences of Root Microcracks Caused by Hand and Rotary File System at Different Lengths

International Healthcare Research Journal ◽

10.26440/ihrj/0309.12004 ◽

2019 ◽

Vol 3 (9) ◽

pp. 283-289

Author(s):

Shuchi Sukul ◽

Goldy Rathee ◽

Parimal Anand ◽

Sakshi Kataria ◽

Pratibha Taneja

Keyword(s):

File System ◽

Statistical Significance ◽

File Systems ◽

In Vitro Study ◽

Root Surface ◽

P Value ◽

Chi Square ◽

Chi Square Test ◽

Group B

OBJECTIVES: The present research was conducted to assess incidences of root microcracks caused by hand and rotary file system at different lengths MATERIAL AND METHODS: This in-vitro study was undertaken to assess incidence of root microcracks caused by hand and rotary file system at different lengths In total, 100 the mandibular premolar with straight roots determined with intact, fully formed apices were taken. Samples were randomly distributed into 5 groups based on the file system used: a) Group A: Control, b) Group B: Reciproc, c) Group C: WaveOne, d) Group D: One Shape and e) Group E: ProTaper. Pearson Chi-square test was used to determine the differences between groups. The dentinal defects were expressed as percentage of samples with microcracks in each group. Level of statistical significance was set at p-value less than 0.05. RESULTS: The chi square test was used to compare the Distribution of the number of teeth in which cracks were observed on the horizontal sections. It was found to be significant with group ProTaper showing maximum cracks at 3,6,9 mm level as compared to other file systemCONCLUSION: Nickel-titanium instruments causes cracks on the apical root surface or in the root canal wall. ProTaper causes maximum dentinal cracks as compared to other file systems

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Open VS Closed Techniques for Laparoscopic Abdominal Surgeries

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i54b33789 ◽

2021 ◽

pp. 296-302

Author(s):

Obaid Ul Haseeb ◽

Haris Rashid ◽

Afrin Ahmed ◽

Mir Arsalan Ali ◽

Shakil Alam ◽

...

Keyword(s):

Controlled Trial ◽

P Value ◽

Open Approach ◽

Chi Square ◽

Closed Technique ◽

Chi Square Test ◽

Group A ◽

Classic Technique ◽

Group B ◽

Surgery Department

Background: Laparoscopic surgery or "minimally invasive" surgery is a type of specialist surgery. The most crucial, demanding, and risky part of the laparoscopy is the creation of pneumoperitoneum. The two most prevalent methods for creating a pneumoperitoneum are the closed and open approaches. Despite the fact that there is no universal consensus on the best approach to gain access to the peritoneal cavity in order to create a pneumoperitoneum. The aim of present study was to compare the operative time and post-operative outcome associated with closed technique and open classic technique. Methods: This randomized controlled trial was carried out by recruiting patients presented in surgery department of Ziauddin Hospital North campus. The samples were divided into two equal groups A and B. Group A was operated for Laparascopic abdominal surgery by open technique while group B operated through closed technique. Effectiveness of procedures was measured by number of complications occurred during and after surgery. Chi-square test and independent T-test were applied for association. P-value of < 0.05 was considered as significant. Results: Mean age was found to be 45.5±16 years and mean weight was 68±10.5 kilograms. Mean time of operations was 84.5±18.5 minutes. 60 (69.8%) of patients included underwent the laparoscopic cholecystectomy while 15 (17.4%) patients had laparoscopic appendectomy. 13/86: 15.1% of patients had the minor complication including 12/43: 27.9% in group B and 1/43: 2.3% in group A. The comparative analysis between the two groups in terms of effectiveness of either method compared by means of development of the complications was found to be highly significant with p value 0.002. Conclusion: The open approach to laparoscopic entrance has been linked to fewer surgical problems than the closed approach.

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Functional outcome of endoscopic and external dacrocystorhinostomy in a teaching hospital

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20190102 ◽

2019 ◽

Vol 5 (2) ◽

pp. 358

Author(s):

Arvind Varma ◽

Sushobhan Dasgupta

Keyword(s):

Prospective Study ◽

Success Rate ◽

Nasolacrimal Duct ◽

P Value ◽

Chi Square ◽

Chi Square Test ◽

Endonasal Dcr ◽

Post Traumatic ◽

External Dcr

Background: The objective of the study was to compare & analyse the results of two different techniques of dacrocystorhinostomy (endonasal and external) in different etiological groups.Methods: This prospective study was carried out for nasolacrimal duct obstruction from October 2016 to October 2018 who underwent dacrocystorhinostomy by two different methods. The patient was divided into two groups one who underwent endonasal DCR (n=55) and another group who underwent external DCR (n=55). In each group they were subdivided into 3 groups on the basis of aetiology into idiopathic, post traumatic and revision cases. The results were evaluated in follow up period of 6 months. At the end of the study, decoding of the groups was done and the results were analysed statistically, using Chi Square test and student t-test, using SSPS III software. P value of less than 0.05 was considered statistically significant.Results: The success rate in endonasal DCR and external DCR was almost same in all the three groups (p>0.05).Conclusions: This prospective study shows that both the methods have almost same success rate. This study also emphasises proper case selection and interdepartmental cooperation for optimum results.

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Perbandingan Insidensi Hipotensi Saat Induksi Intravena Propofol 2 Mg/Kg Bb Pada Posisi Supine dengan Perlakuan dan Tanpa Perlakuan Elevasi Tungkai

Jurnal Kesehatan Andalas ◽

10.25077/jka.v5i1.476 ◽

2016 ◽

Vol 5 (1) ◽

Author(s):

Beni Indra ◽

Untung Widodo ◽

Yunita Widyastuti

Keyword(s):

Randomized Control Trial ◽

Elective Surgery ◽

P Value ◽

Chi Square ◽

Parametric Data ◽

Chi Square Test ◽

Group A ◽

Randomized Control ◽

American Society ◽

Group B

Abstrak Penggunaan Propofol untuk induksi pada general anestesi dapat menyebabkan hipotensi akibat vasodilatasi arteri dan vena terutama vena kapasitan ditungkai. Manuver elevasi tungkai dapat mempertahankan stabilitas hemodinamik dengan meningkatkan aliran balik vena ke jantung dan mengurangi penumpukan darah di vena kapasitan tungkai. Penelitian ini dirancang dengan menggunakan cara Open Randomized Control Trial. Subyek penelitian adalah 184 sampel pasien dewasa ASA I-II yang menjalani operasi elektif dengan menggunakan general anestesi dengan induksi propofol. Kelompok sampel penelitian dibagi dalam dua kelompok masing-masing berjumlah 92 orang. Setelah prabeban cairan RL 10 cc/kgbb dan pemberian fentanyl 2 mcg/kgbb dan midazolam 0,05 mg/kgbb maka kelompok A dilakukan elevasi tungkai 45º satu menit sebelum induksi propofol dan dipertahankan sampai penelitian selesai. Sedangkan kelompok B tidak dilakukan elevasi tungkai. Data yang dikumpulkan dianalisa dengan uji t tes. Untuk data proporsi dilakukan analisa dengan tes chi-square. Dari data demografi tidak didapatkan perbedaan yang bermakna secara statistik (p>0,05) antara kedua kelompok penelitian kecuali untuk BMI (p<0,05). Insidensi hipotensi menit pertama pasca induksi propofol pada kelompok A (elevasi tungkai) secara signifikan lebih rendah (12%) dibanding kelompok kontrol B (27,2%) (p=0,016; p < 0,05). Pada menit ketiga pasca induksi juga didapatkan insidensi hipotensi kelompok A (15,2%) signifikan lebih rendah dibanding kelompok B (23,9%) (p= 0,014; p < 0,05). Elevasi tungkai 45 derajat efektif dalam menurunkan insidensi hipotensi pasca induksi propofol. Kata kunci: propofol, hipotensi, elevasi tungkai AbstractThe induction of general anaesthesia with propofol may induce of considerable degree of hypotension that has been atributed to decrease in systemic vascular resistance caused by combination of venous and arterial vasodilatation. It will produce a shifting of blood to venous reservoir, especially capacitance venule of legs. Leg elevation can provide hemodynamic stability by increases cardiac preload and recruits blood contained in the venous reservoir. This is Open Randomized Control Trial include 184 elective surgery patients with American Society of Anaesthesiologist (ASA) physical status I and II. Anesthesia was induced with propofol. Patients were randomly allocated into two groups with 92 patients in each. All the patients received Ringer’s Lactate (10 ml/kg) and premedicated with fentanyl (2 mcg/kg) and midazolam (0,05 mg/kg) before induction of anesthesia. Group A was performed passive leg raising 45 degree 1 minute before injection of propofol until the end of study and group B (control) did not receive any maneuver. Parametric data were analyzed with t-test and categorical data was done by using Chi-square test. A p value of less than 0,05 was consider significant. Demografic characteristics (age, sex, body weight and height) and baseline haemodynamic parameters of the patients were similar in two groups (p > 0.05) except for BMI (p < 0.05) . The incidence of hypotension was significantly lower in group A (12 %, ) than group B (27,2%) at the first minute after propofol injection, p value = 0.016 (p < 0,05). In the third minute, incidence of hypotension was also significantly lower in group A (15,2%) than group B (23,9%), p value = 0,014 (p < 0,05). Leg elevation maneuver 45º significantly decrease incidence of hypotension after propofol induction. Keywords: Propofol, hypotension, leg elevation

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2ND TRIMESTER PREGNANCY

The Professional Medical Journal ◽

10.29309/tpmj/2018.25.04.350 ◽

2018 ◽

Vol 25 (04) ◽

pp. 577-581

Author(s):

Sobia Tabassum ◽

Arshia Sabir ◽

Hafiz Muhammad Anwar ul Haq ◽

Hafiz Muhammad Ejaz ul Haq

Keyword(s):

Sampling Technique ◽

P Value ◽

Chi Square ◽

Prostaglandin F2a ◽

Oxytocin Infusion ◽

Successful Induction ◽

Chi Square Test ◽

Group A ◽

Test Of Significance ◽

Group B

Objectives: To compare the effectiveness of prostaglandin F2á by extra amnioticroute and I/V oxytocin infusion for induction of labor in 24 hours. Study Design: This wasa randomized control study. Place and Duration of the Study: This study was conductedat the department of Obstetrics & Gynaecology, Civil Hospital, Bahawalpur from March 2017to October 2017. Materials and Methods: A total number of 104 patients (52 given PGF2áand 52 increasing infusion rate of I/V oxytocin) between 13 to 26 weeks of gestation wereenrolled using non-probability purposive sampling technique. Two groups ‘A’ and ‘B’ wereformed having patients of comparable age, parity and gestational age to minimize the effectof confounders. Both the groups were compared for induction delivery interval (hours), andcomplications. Chi square test was used as test of significance and any value <0.05 was takenas statistically significant. Results: The ages of patients ranged from 16-45 years (28.93 + 8years). Gestational ages were between 13-26 weeks (mean 16.48 + 6.43 weeks). The parityranged from 0-9 (mean 3.9 + 2.87). Missed abortion was the major reason for TOP, seen in 71(68.3%). In Gorup-A, all patients aborted / delivered within 28 hours from the start of the infusionso got successful induction in 100% patients whereas 5 (9.6%) patients failed in Group B. InGroup A, successful induction of delivery was done in significantly less interval (11.27+6.2hours) as compared to Group B (18.4+10.8 hours) with a statistically significant p value of0.016.There were 3 (5.8%) patients in Group A and 10 (19.2%) in Group B who developed oneor more complications and this difference turned out to be statistically significant (p=0.038).No major complications developed in any of the groups. Conclusion: Extra amniotic PGF2á ismore effective than I/V Oxytocin for termination of pregnancy.

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Role of l-arginine in the prevention of pre eclampsia in high-risk pregnancies.

The Professional Medical Journal ◽

10.29309/tpmj/2022.29.01.5613 ◽

2021 ◽

Vol 29 (01) ◽

pp. 62-66

Author(s):

Nadia Taj ◽

Asma Sajid ◽

Tehreem Rasheed ◽

Anam Naz ◽

Saba Javed ◽

...

Keyword(s):

Placebo Group ◽

High Risk ◽

Gestational Age ◽

P Value ◽

Chronic Hypertension ◽

Chi Square ◽

Group Efficacy ◽

Chi Square Test ◽

Group A ◽

Group B

Objective: To compare the efficacy of L-Arginine versus placebo in the prevention of pre eclampsia in high-risk pregnancies. Study Design: Randomized Control Trial. Setting: Department of Obstetrics and Gynecology, Nishtar Hospital Multan. Period: November 2019 to February 2019. Material & Methods: A total of 130 women were included in the study. 65 patients were in L-arginine group or Group A while 65 patients were in placebo group or Group B. In group A, women were prescribed L-arginine 300 grams (Amino Whey Sachet) once a day until delivery and in group B; women were given homologated placebo (starch) once a day until delivery. Efficacy (no preeclampsia occurs during pregnancy) was noted from both groups and recorded. Mean ±SD was presented for quantitative variables like age, gestational age, parity, duration of chronic hypertension, weight, height and BMI. Variables such as age, parity, hypertension, body mass index, gestational age and duration of hypertension were stratified to assess their effect on efficacy. Chi square test was used to make comparison of the efficacy in both groups as well as for post-stratification for both groups. A p value of less than or equal to 0.05 was taken as significant. Results: In L-arginine group efficacy was 92.3% as compared to 69.2% in placebo group (p< 0.000) Table-IV. Conclusion: It can be concluded that L-arginine when given orally at the dose of 300g daily has a considerable role in prevention of pre-eclampsia in pregnant patients with high risk and also has a role in reduction of severity of pre-eclampsia.

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Comparison of Ovulation Induction with Letrozole with Metformin Versus Letrozole Alone in Females Presenting with Polycystic Ovarian Syndrome

Esculapio ◽

10.51273/esc20.2516412 ◽

2021 ◽

Vol 16 (4 (oct 2020 - dec 2020)) ◽

Author(s):

Zubda Aiman ◽

Amna Khanam ◽

Mahliqa Maqsood ◽

Mehwish ayyaz ◽

Miss Alia ◽

...

Keyword(s):

Ovulation Induction ◽

Polycystic Ovarian Syndrome ◽

Controlled Trial ◽

P Value ◽

Chi Square ◽

Induction Rate ◽

Chi Square Test ◽

Group A ◽

Group B ◽

Ovarian Syndrome

Objective: To compare the frequency of Ovulation Induction after administration of Letrozole with metformin versus Letrozole alone in females presenting with Polycystic Ovarian Syndrome Methods: This Randomized Controlled Trial was done in unit 5 of Lady Aitchison Hospital Lahore for 6 months. Total 200 females fulfilling the inclusion criteria were recruited from OPD. Lottery method was used for randomization of study subjects. Females in group A were given Letrozole 2.5mg once a day for five days (from third to seventh day)of the cycle for three consecutive months and metformin 1500mg (500mg 3 times a day) daily for three months, while females in group B were given Letrozole 2.5mg once a day for five days (from third to seventh day) le for three consecutive months. Then they were followed up in OPD for 3 cycles. In all 3 cycles TVS was done on day 12 to access the number of follicles and to measure the size of largest follicle, and on day 21 of cycle progesterone level will be assessed for confirmation of ovulation induction. The data was entered and analyzed through SPSS version 20. Mean and standard deviation was calculated for age and BMI. Frequency and percentage was calculated for Ovulation induction. Both groups were compared by using chi-square test taking p-value<0.05 as significant. Data was stratified for BMI (Normal, overweight and Obese).After stratification chi-square test was applied keeping a p value < 0.05 as significant. Results: In Group-A mean age of women was 28.18±6.58 years. In Group-B mean age of women was 27.08±5.15 years. In Group-A ovulation induction rate was much higher as compared to that of Group-B women. i.e. (89% vs. 60%). p-value=0.000. Ovulation induction rate was significantly higher with Letrozole+ Metformin in women who were having normal BMI, overweight & obese as compared to that of Letrozole alone. Conclusion: Letrozole with metformin is more effective for the ovulation Induction females presenting with polycystic ovarian Syndrome as compared to letrozole alone.() Key Words: Polycystic Ovarian Syndrome, Management, Ovulation Induction, Letrozole, Metformin How to Cite: Aiman Z, Khanam A, Maqsood M, Ayyaz M, Alia, Kanwal K. Comparison of ovulation induction with letrozole with metformin versus letrozole alone in females presenting with polycystic ovarian syndrome. Esculapio.2020;16(04):54-58.

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A Comparative Study on the effect of Padabhyanga with Tila Taila and Nimba Taila in management of Vipadika w.s.r. to Padasputana

Journal of Ayurveda and Integrated Medical Sciences (JAIMS) ◽

10.21760/jaims.v3i4.13279 ◽

2018 ◽

Vol 3 (4) ◽

Author(s):

Dr. Asha Karki ◽

Dr.Mallikarjun S. Yalagond ◽

Dr.Venkatesh Illal

Keyword(s):

Food Habits ◽

Complete Relief ◽

Chi Square ◽

Medical College ◽

Comparative Clinical Study ◽

Chi Square Test ◽

Group A ◽

Group B ◽

Better Than

Background: Vipadika affects irrespective of age, sex and socioeconomic status. The causes may be excessive/barefoot walking, contact with dust, detergents and improper food habits. Here control over Vatadosha is important which can be achieved through Padabhyanga. Materials and Methods: It was a comparative clinical study of 30 patients, who were selected by random sampling from the OPD of S.M.V.V.S, R.K.M Ayurveda Medical College, Vijayapura, and categorized into 2 groups as 'A' and 'B', each consisting of 15 patients and were advised Tila Taila and Nimba Taila Padabhyanga for 30 days respectively. Follow up was advised on 45th day of treatment. Severities of the symptoms were assessed before, after treatment and after follow up. Results: In group-A 20% of patients showed complete relief and in group-B 0% have showed complete relief. Conclusion: Tila Taila is having Sara, Sukshma Guna and pacifies Vatakapha Dosha. Nimba Taila is Kushtagna, Krimigna. Both Tailas help in reducing Rukshata and Sputana. Vipadika can be correlated with cracked heels. The results were assessed statistically by Pooled chi square test. It was concluded that group-A patients were significantly better than group-B after follow up. Hence Tila Taila Padabhyanga is beneficial in Vipadika.

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Comparison of Outcome of Decompressive Craniectomy with Wide Dural Flap Duraplasty Versus Dural Slits in the Management of Post Traumatic Acute Subdural Hematoma in Terms of Postoperative CSF Leak

Pakistan Journal Of Neurological Surgery ◽

10.36552/pjns.v23i3.350 ◽

2019 ◽

Vol 23 (3) ◽

pp. 163-169

Author(s):

GHAYUR ABBAS ◽

RIFFAT ULLAH KHAN ◽

USAMA BIN ZUBAIR ◽

SAJID NAZEER BHATTI

Keyword(s):

Decompressive Craniectomy ◽

Acute Subdural Hematoma ◽

Csf Leak ◽

P Value ◽

Chi Square ◽

Csf Leakage ◽

Group A ◽

Post Traumatic ◽

The Difference ◽

Group B

Objective: To compare the frequency of postoperative cerebrospinal fluid (CSF) leak after decompressive craniectomy with wide dural flap duraplasty versus dural slits in patients with post traumatic acute subdural hematoma.Material and Methods: The study was conducted from August 2017 to February 2018 in the Department of Neurosurgery, PIMS, Islamabad. A total of ninety-two (n = 92) adult patients of either gender between age 15-55 years presented with isolated, unilateral traumatic acute sub dural hematoma (ASDH) with midline shift of 5mm were categorized into 2 groups; Group A (DC with open dural flap) and Group B (DC with dural slits). Patients were observed for CSF leakage for four weeks.Results: Results showed that the overall frequency of CSF leak was not significantly different in both groups and revealed that the CSF leak was observed in 10.9% (n = 5/46) in group A (DC plus open dural flap) and in 21.7% (n = 10/46) in group B (DC plus dural slits) (P = 0.158). The difference was not significant in terms of frequency of CSF leak in both groups when results were stratified with respect to gender, age, duration of trauma and baseline GCS. P value (chi-square) was found to be > 0.05 in all cases.Conclusions: The postoperative CSF leak was observed in higher percentages in patients who underwent DC with dural slits as compared to the patients who underwent DC with open dural flaps for surgical management of ASDH. The difference, however, was not statistically significant.

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