scholarly journals A phyto pharmacological review of medicinaly important plant solena amplexcaulis (cucurbitaceae)

2021 ◽  
Vol 8 (2) ◽  
pp. 44-48
Author(s):  
Krishnamoorthy Karthika ◽  
Vimal Priya Subramanian
Keyword(s):  
Wound Healing ◽  
Microbial Activity ◽  
Tamil Nadu ◽  
Medicinal Uses ◽  
Southern Asia ◽  
Solena Amplexicaulis ◽  
Anti Oxidant

Solena amplexicaulis, (Cucurbitaceae) commonly known as the creeping cucumber, native to tropical southern Asia. It is generally prescribed for wound healing by the local healers in western districts of Tamil Nadu. The fruits, leaves, roots and shoots have used as food and it is traditionally used as astringent, appetizer, carminative, cardiotonic, digestive, diuretic, expectorant, invigorating, purgative and stimulant. It have lot of medicinal uses such as antioxidant antidiabetic, antibacterial etc. The available reports on physicochemical, anti-microbial activity, anti-oxidant activity and pharmacological value of Solena amplexicaulis are discussed in this review.

Anti-microbial and Anti-oxidant Properties of Solvent Extract of Lichen Species Collected from Kodaikanal Hills, Western Ghats of Tamil Nadu

Phytomedicine ◽  
2020 ◽  
pp. 53-61 ◽  
Author(s):  
R. Kalidoss ◽  
M. Mariraj ◽  
M. Shenbagam ◽  
J. Merlin Seles ◽  
K. Arun Prasath ◽  
...  
Keyword(s):  
Western Ghats ◽  
Tamil Nadu ◽  
Lichen Species ◽  
Solvent Extract ◽  
Anti Oxidant

scholarly journals More natural more better: triple natural anti-oxidant puerarin/ferulic acid/polydopamine incorporated hydrogel for wound healing

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Qianmin Ou ◽  
Shaohan Zhang ◽  
Chuanqiang Fu ◽  
Le Yu ◽  
Peikun Xin ◽  
...  
Keyword(s):  
Wound Healing ◽  
Ferulic Acid ◽  
Natural Antioxidants ◽  
Wound Dressings ◽  
Polyethylene Glycol Diacrylate ◽  
Glycol Diacrylate ◽  
Antioxidant Function ◽  
Healing Tissue ◽  
Anti Oxidant ◽  
Gel Network

Abstract Background During wound healing, the overproduction of reactive oxygen species (ROS) can break the cellular oxidant/antioxidant balance, which prolongs healing. The wound dressings targeting the mitigation of ROS will be of great advantages for the wound healing. puerarin (PUE) and ferulic acid (FA) are natural compounds derived from herbs that exhibit multiple pharmacological activities, such as antioxidant and anti-inflammatory effects. Polydopamine (PDA) is made from natural dopamine and shows excellent antioxidant function. Therefore, the combination of natural antioxidants into hydrogel dressing is a promising therapy for wound healing. Results Hydrogel wound dressings have been developed by incorporating PUE or FA via PDA nanoparticles (NPs) into polyethylene glycol diacrylate (PEG-DA) hydrogel. This hydrogel can load natural antioxidant drugs and retain the drug in the gel network for a long period due to the presence of PDA NPs. Under oxidative stress, this hydrogel can improve the activity of superoxide dismutase and glutathione peroxidase and reduce the levels of ROS and malondialdehyde, thus preventing oxidative damage to cells, and then promoting wound healing, tissue regeneration, and collagen accumulation. Conclusion Overall, this triple antioxidant hydrogel accelerates wound healing by alleviating oxidative injury. Our study thus provides a new way about co-delivery of multiple antioxidant natural molecules from herbs via antioxidant nanoparticles for wound healing and skin regeneration. Graphic Abstract

scholarly journals In vitro antimicrobial, anti-oxidant properties and GC-MS analysis of the crude methanolic extract and fractions of Solanum dasyphyllum Schumach and Thonn. leaves

2020 ◽  
Author(s):  
Oladapo Elijah Oyinloye ◽  
Olumuyiwa. S. Alabi ◽  
Olusegun. G. Ademowo
Keyword(s):  
Crude Extract ◽  
Skin Diseases ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Kinetics Study ◽  
Medicinal Uses ◽  
Ms Analysis ◽  
Soxhlet Apparatus ◽  
Anti Oxidant ◽  
Time Kill

Abstract Background: Solanum dasyphyllum is a plant with several ethno-medicinal uses as food and medicine in treatment of fever, skin diseases, inflammation, stomach ache and some systemic infections. To date there is little scientific validation of the folkloric claims of S. dasyphyllum compared to other species of the Solanaceae family. This study determined the antimicrobial and antioxidant potential of methanol extract and fractions of the leaves of S. dasyphyllum and analysed the phyto-constituents using GC-MS technique.Methods: The dried leaves of S. dasyphyllum were extracted by Soxhlet apparatus with 80% methanol and the crude extract subjected to Phytochemical screening and liquid-liquid fractionation. Crude extract and fractions were subjected to antimicrobial screening, minimum inhibitory concentrations (MICs) and minimum bactericidal/fungicidal concentrations (MBC/MFC) determination and time-kill kinetics study. Crude extract was assayed for antioxidant activity and analysed by GC-MS.Results: Percentage yield of S. dasyphyllum was 12.5% and tested positive for flavonoids, alkaloids, saponins, cyanogenic glycosides, tannins and reducing sugars. The crude extract and fractions were active on all the isolates at concentrations >0.5 mg/mL. MICs of the crude extract and fractions ranged between 0.25 and >4 mg/mL, MBC ranged between 1 and >4 mg/mL and MFC ranged between 0.5 and >4 mg/mL. The MBC/MIC ratio was >4 for dichloromethane fractions against S. aureus (ratio 8) and MFC/MIC ratio ethylacetate fraction against the fungi isolates (ratio 8). The time-kill kinetics study showed dichloromethane and ethylacetate fractions to be bactericidal with zero viable count at 4 - 6hours against the isolates. The crude extract displayed moderate antioxidant with weak DPPH radical scavenging activity. The GC-MS analysis showed 29 metabolites including the phenols and polyphenols derivatives, eucalyptol, levomenthol, benzofuranone derivative, diethyl phthalate, neophytadiene, 1-Docosene, 17-Pentatriacontene, Phytol, Thunbergol and esters of decanoic acid derivatives all of which are known to have anti-infective and anti-oxidant properties.Conclusion: This study therefore confirmed the ethno-medicinal claim of S. dasyphyllum and thus elucidates the potentials of the plant as a good source of bioactive compounds including those with strong anti-infective and antioxidant properties.

scholarly journals Medicinal Plants from Vettangudi Water Bird Sanctuary in Sivagangai District of Tamil Nadu, Southern India

2021 ◽  
Vol 11 (2) ◽  
pp. 135-140
Author(s):  
S Shanmugam ◽  
C P Muthupandi ◽  
V M Eswaran ◽  
K Rajendran
Keyword(s):  
Medicinal Plants ◽  
Plant Species ◽  
Tamil Nadu ◽  
Medicinal Uses ◽  
Traditional Medicines ◽  
Water Bird ◽  
Plant Parts ◽  
Healthcare Needs ◽  
The People ◽  
Exploitation And Utilization

Most of the people depending on traditional medicine to meet their primary healthcare needs. Documenting the indigenous knowledge through ethnobotanical studies is important for the conservation of biological resources as well as their sustainable utilization. It is also necessary to collect the information about the knowledge of traditional medicines before it is permanently lost. Having all these facts in mind, the present study was carried out to document the plants used as medicine by the people inhabiting around the Vettangudi Water Bird Sanctuary of Sivagangai district in Tamil Nadu, India. The field survey was conducted in two villages situated near to Vettangudi Water Bird Sanctuary. The medicinal uses of 40 angiospermic plant species belonging to 36 genera of 24 families for various diseases and ailments were recorded by this study. The people inhabiting in the study area used 45 herbal therapies prepared from 40 plants to treat 27 different illnesses. Regarding the plant parts used, leaf was the mostly used plant part (51.16%) and extract was found as mostly followed mode (42.28%) to treat a particular disease. Attention should be made on proper exploitation and utilization of these medicinally important plant species. Keywords: Medicinal plants, Vettangudi Water Bird Sanctuary, Sivagangai district, Tamil Nadu.

scholarly journals Medicinal Plants Used to Heal Wound in Karandamalai of Dindigul District in Tamil Nadu, Southern India

2021 ◽  
Vol 11 (2) ◽  
pp. 72-75
Author(s):  
N Yasothkumar
Keyword(s):  
Wound Healing ◽  
Medicinal Plants ◽  
Tamil Nadu ◽  
Southern India ◽  
Mode Of Administration ◽  
Therapeutic Uses ◽  
Research Theme ◽  
Treatment Of Wounds ◽  
Scientific Name

Due to the presence of antibiotic or antiseptic nature’s chemicals, plants are remarkable for the treatment of wounds. Having this fact as research theme, the present study was carried out to document the therapeutic uses of medicinal plants used to heal wound in Karandamalai of Dindigul district in Tamil Nadu. The frequent fieldwork was conducted from October 2019 to January 2020 for this study. The scientific name, family name, local name (in Tamil), part(s) used, mode of preparation, and mode of administration of medicine were recorded. A total of 24 medicinal remedies prepared from 24 plants were recorded. Further research on the phytochemistry and pharmacology of these medicinal plants should be conducted. Keywords: Medicinal plants, Wound healing, Karandamalai, Dindigul district, Tamil Nadu.

scholarly journals Phytochemical analysis, anti-oxidant and anti-microbial activity of Acalypha indica leaf extracts in different organic solvents

2016 ◽  
Vol 8 (3) ◽  
pp. 444 ◽  
Author(s):  
Chekuri Sudhakar ◽  
Narendar Vankudothu ◽  
Shivaprasad Panjala ◽  
Nirmala Babu Rao ◽  
Roja Rani Anupalli
Keyword(s):  
Ethyl Acetate ◽  
Petroleum Ether ◽  
Microbial Activity ◽  
Leaf Extract ◽  
Antioxidant Properties ◽  
Soxhlet Extraction ◽  
Phytochemical Analysis ◽  
Leaf Extracts ◽  
Anti Oxidant ◽  
Acalypha Indica

The herb <em>Acalypha indica </em>which belongs to Euphorbiaceae family has multiple medicinal properties which include anti-oxidant, anti-bacterial, anti-fungal, anti-inflammatory, antiulcer, anti-helmintic, anti-cancerous, anti-venom, and neuro-protective activity. The present study was designed to evaluate the phytochemical, antimicrobial and anti-oxidant activity of <em>Acalypha indica </em>leaves extracts in different solvent extractions like methanol, hexane, ethyl acetate and petroleum ether. Fresh leaves of the plant were collected and shade dried. Dried leaves were milled to obtain powder. Powder was subjected to soxhlet extraction using solvents and extracts were successively obtained. Phytochemical analysis was conducted following standard methods.  Phytochemical analysis showed the presence of Alkaloids, Phenols, Saponins, Flavanoids and Amino acids. Leaf extract of methonal have shown the highest anti-oxidation capacity than hexane, ethyl acetate and petroleum ether. Anti-microbial activity has been performed on microbes like <em>Bacillus sps</em>, <em>E.coli,</em> <em>Psuedomonas sps</em> and <em>Streptococcus sps.</em> A highest value of zone of inhibition was found in methanol extract against <em>E.coli.</em> These results provide evidence that <em>Acalypha indica </em>leaf extract possesses vital phytochemicals, antimicrobial and antioxidant properties. Hence this plant can be studied further for drug analysis for finding potent medicines for diseases.

scholarly journals Bauhinia purpurea: An Updated Pharmacological Profile

2020 ◽  
Vol 6 (2) ◽  
pp. 81-85
Author(s):  
SumitKArora ◽  
◽  
MaviyaHussain ◽  
SubhashRYende ◽  
KeshavMoharir ◽  
...  
Keyword(s):  
Wound Healing ◽  
Cardiac Activity ◽  
Pharmacological Profile ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Cytoprotective Activity ◽  
Bauhinia Purpurea ◽  
Anti Inflammatory ◽  
Pharmacological Potential

Bauhinia purpurea (B. purpurea) (family: Fabaceae) commonly called as butter fly tree has vast medicinal uses and remarkable pharmacological potential. Various phytoconstituents, extracts and parts of this plant were possess significant pharmacological activities such as cardiac activity, antifungal, wound healing, antidiabetic, antiulcer, antioxidant, antinociceptive, hepatoprotective, nephroprotective, antidiarrhoeal, anti-inflammatory, antipyretic, analgesic, antimalarial, gastro protective and cytoprotective activity. The present study emphasizes the overview of recent studies and/or updates on pharmacological potential of B. purpurea.

scholarly journals Evaluation of anti-oxidant and anti-microbial activity of various essential oils in fresh chicken sausages

2017 ◽  
Vol 54 (2) ◽  
pp. 279-292 ◽  
Author(s):  
Heena Sharma ◽  
S. K. Mendiratta ◽  
Ravi Kant Agarwal ◽  
Sudheer Kumar ◽  
Arvind Soni
Keyword(s):  
Essential Oils ◽  
Microbial Activity ◽  
Anti Oxidant

Macro-microscopic Atlas on Heartwood of Pterocarpus santalinus L.f. (Red sandalwood)

2021 ◽  
pp. 3927-3930
Author(s):  
Susikumar S ◽  
Nartunai G ◽  
Ilavarasan R
Keyword(s):  
Wound Healing ◽  
Medicinal Plant ◽  
Calcium Oxalate ◽  
Tamil Nadu ◽  
Andhra Pradesh ◽  
South India ◽  
Deciduous Tree ◽  
Starch Grains ◽  
Herbal Formulation ◽  
Pterocarpus Santalinus

Background: Pterocarpus santalinus L.f. (Fam. Leguminosae) is a medium sized, deciduous tree distributed in South India mainly in Andhra Pradesh, Karnataka and Tamil Nadu. The heartwood is highly prized and medicinally useful. The heartwood is used in Indian system of medicine for leucorrhoea, piles, syphilis, vomiting, fever, thirst, purifying blood and in wound healing. Pterocarpus santalinus is one of the ingredients in many Siddha and Ayurvedic formulations namely Cintil Ney, Senchandana Manapagu, Candana Bala, Laksadi Taila and Candanadi lauha. Objective: The present study brings out macro-microscopic atlas on heartwood of medicinal plant Pterocarpus santalinus L.f. Materials and Methods: Sections and powder were observed and photographed under different magnifications with the help of Olympus BX51 Microscopic unit fitted with Olympus Camera. Results: Macroscopically colour, odour and taste; microscopically tyloses, needle eye end fibres, forked fibres with pegged and sharp end, pitted and border pitted vessels, uni-seriate medullary rays, Reddish brownish content, oil globules, simple starch grains, crystal fibres and prismatic crystals of calcium oxalate are the unique diagnostic characters reported. Conclusion: The finding of the present study is believed to be helpful in identifying the genuineness of the heartwood in crude raw drug and also in standardization of herbal formulation containing red sandalwood as ingredient.

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