A clinico-epidemiological study of acne vulgaris conducted at a tertiary care hospital, Tamil Nadu
Background: Acne is a chronic, self-limiting inflammatory disease of pilosebaceous unit. It is multifactorial, of which Propionibacterium acne and Sebum play an important role in etiopathogenesis. Aim: To study the clinico-epidemiological characteristics of patients with acne vulgaris attending the Out Patient Department of Dermatology at a tertiary care hospital, in Tamil Nadu state of India. Material and Methods: This is a Cross sectional study conducted in patients who are attending to the Outpatient Department of Dermatology in Meenakshi Medical College and Research Institute, Tamil Nadu. A total of 50 apparently healthy male and non-pregnant females aged between 12 years and 35 years with clinical diagnosis of acne grade 1 and 2 with facial lesions only are selected and recruited for the study. Pregnant and lactating women, patients who are hypersensitive to retinoids and presented with any other skin condition that would interfere with diagnosis or assessment of acne were excluded from the study. Study subjects were divided into two groups. One groups was treated with Adapalene and the other group was treated with Tretinoin. Both the groups were compared for the clinico-epidemiological characteristics. Results: A total of 50 patients were recruited for the study (n=50). Out of the 50 patients, 20 were males (40%) and 30 were females; 28 patients were students (that is 56%) and 22 (that is 44%) were completed their studies or not going to school or college for studies. Among the 50 patients 32 were unmarried and 18 were married. Based on the duration of Acne, subjects were divided into three groups: - below 1 year, 1-2 year and above 2 years. All the clinico-epidemiological parameters were compared for analysis. Conclusion: It was observed that 24% of the study population showed a positive family history of acne and diet is the major precipitating factor for the development of Acne among all the affected patients. So suggestions of change in dietary habits to be given to Acne patients for better outcome.