scholarly journals Clinical and epidemiological characteristics and hormonal profile of adult females with acne vulgaris: a cross-sectional study from a tertiary care hospital

2021 ◽  
Vol 7 (3) ◽  
pp. 440
Author(s):  
Nidhi Shah ◽  
Faaria Ali ◽  
Aswathy Radhakrishnan ◽  
Parag Chaudhari ◽  
Anant Patil ◽  
...  
Keyword(s):  
Adult Female ◽  
Serum Insulin ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cross Sectional ◽  
Hormonal Profile ◽  
Female Patients ◽  
Adult Females ◽  
Epidemiological Characteristics

<p class="abstract"><strong>Background: </strong>To study clinical and epidemiological characteristics and hormonal profile of adult females with acne</p><p class="abstract"><strong>Methods: </strong>Adult female patients of &gt;25 years of age with acne were enrolled. Demographic profile, habits, location of acne lesions, associated disease and acne flare association with menstrual cycle were noted. Prevalence of abnormalities in testosterone, dihydroepiandrosterone-sulfate (DHEAS), prolactin, luteinizing hormone (LH), follicle stimulating hormone (FSH), LH:FSH ratio, anti-mullerian hormone (AMH), and serum insulin were noted. Ultrasound (abdomen and pelvis) was performed for screening the presence of any abnormality.</p><p class="abstract"><strong>Results:</strong> Fifty one patients [mean (SD) age 30.96 (4.93) years] were included in the study. Thirty six (70.59%) patients had persistent type of acne. Grade 2 acne was present in 40 (78.43%) patients. Oily skin was seen in 27 (52.94%) patients. Hirsuitism and menstrual irregularity was present in 24 (47.06%) and 13 (25.49%) patients respectively. Pigmentation and scarring was present in 27 (52.94%) and 35 (68.63%) patients respectively. Acne lesions were seen on cheeks in 36 (70.59%) patients. Eight (15.69%) patients had elevated testosterone. DHEAS and prolactin levels were normal in all patients. Elevation of LH and decreased FSH levels were seen in five (9.80%) and three (5.88%) patients respectively. Five (9.80%) patients had elevated LH:FSH level. Raised insulin level was seen in 8 (15.69%) patients.</p><p class="abstract"><strong>Conclusions: </strong>Derangement of hormonal profile is not very common among adult female patients with acne. However, in some patients laboratory markers of hyperandrogenism are seen.  </p>

A clinico-epidemiological study of acne vulgaris conducted at a tertiary care hospital, Tamil Nadu

2021 ◽  
Vol 19 (3) ◽  
pp. 133-138
Author(s):  
M Selva Sudha ◽  
Keyword(s):  
Tamil Nadu ◽  
Dietary Habits ◽  
Tertiary Care Hospital ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
Positive Family History ◽  
Skin Condition ◽  
Care Hospital ◽  
Cross Sectional ◽  
Epidemiological Characteristics

Background: Acne is a chronic, self-limiting inflammatory disease of pilosebaceous unit. It is multifactorial, of which Propionibacterium acne and Sebum play an important role in etiopathogenesis. Aim: To study the clinico-epidemiological characteristics of patients with acne vulgaris attending the Out Patient Department of Dermatology at a tertiary care hospital, in Tamil Nadu state of India. Material and Methods: This is a Cross sectional study conducted in patients who are attending to the Outpatient Department of Dermatology in Meenakshi Medical College and Research Institute, Tamil Nadu. A total of 50 apparently healthy male and non-pregnant females aged between 12 years and 35 years with clinical diagnosis of acne grade 1 and 2 with facial lesions only are selected and recruited for the study. Pregnant and lactating women, patients who are hypersensitive to retinoids and presented with any other skin condition that would interfere with diagnosis or assessment of acne were excluded from the study. Study subjects were divided into two groups. One groups was treated with Adapalene and the other group was treated with Tretinoin. Both the groups were compared for the clinico-epidemiological characteristics. Results: A total of 50 patients were recruited for the study (n=50). Out of the 50 patients, 20 were males (40%) and 30 were females; 28 patients were students (that is 56%) and 22 (that is 44%) were completed their studies or not going to school or college for studies. Among the 50 patients 32 were unmarried and 18 were married. Based on the duration of Acne, subjects were divided into three groups: - below 1 year, 1-2 year and above 2 years. All the clinico-epidemiological parameters were compared for analysis. Conclusion: It was observed that 24% of the study population showed a positive family history of acne and diet is the major precipitating factor for the development of Acne among all the affected patients. So suggestions of change in dietary habits to be given to Acne patients for better outcome.

scholarly journals Prevalence and correlates of psychological distress among cancer patients in a tertiary care hospital in northern India

2019 ◽  
Vol 6 (5) ◽  
pp. 2223 ◽  
Author(s):  
Amita Mason ◽  
Ruchi Juyal ◽  
Sai Chandan Das ◽  
Deep Shikha ◽  
Sunil Saini ◽  
...  
Keyword(s):  
Psychological Distress ◽  
Cancer Patients ◽  
Formal Education ◽  
Economic Status ◽  
Tertiary Care ◽  
Depression Scale ◽  
Care Hospital ◽  
Cross Sectional ◽  
Female Ratio ◽  
Female Patients

Background: Patients diagnosed with cancer are usually exposed to high level of mental stress and hence invariably lend in psychological distress. This study aimed to estimate the prevalence of psychological distress amongst cancer patients and determine its association with socio-demographic factors.Methods: This hospital based cross-sectional study was conducted at a cancer research institute of district Dehradun. Purposive sampling was used to select the hospital and recruiting patients. All eligible patients, giving written consent for the study were interviewed and distress related information was gathered using the Hospital Anxiety and Depression Scale (HADS). The data were collected for two months and sample size of 208 was achieved. Data was entered in SPSS 22.0 and association of different variables with psychological distress was determined by chi-square test..Results: The mean age of the surveyed cancer patients was 51.05±15.68 years and the male female ratio was 1.7. Prevalence of psychological distress was found to be 38.5% and significantly more female patients than male patients (47.4% and 33.3% respectively) had distress. The association between psychological distress and increasing age, sex, literacy and employment status was found to be significant.Conclusions: Approximately 39% of cancer patients had psychological distress (anxiety/ depression/ both). The prevalence of psychological distress was found to be significantly higher in female patients, older age, patients with no formal education, unemployment and lower socio-economic status. Appropriate psychiatric interventions/ counselling following diagnosis and during therapy may be effective in reducing distress and improving quality of life in cancer patients.

scholarly journals A study on the dermatology life quality index in patients with acne vulgaris

2019 ◽  
Vol 5 (4) ◽  
pp. 774
Author(s):  
Sangaiah Sivaramakrishnan ◽  
Thomas Jayakar
Keyword(s):  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Significant Impairment ◽  
Life Quality Index

<p class="abstract"><strong>Background:</strong> Acne vulgaris is a common, chronic disorder, involving inflammation of the pilosebaceous units that can be varied in presentation and difficult to treat. Most adolescents experience some acne; however, it may linger into adulthood. This study was done<strong> </strong>to evaluate the dermatology life quality index in patients with acne vulgaris.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study was done with pretested Dermatology life quality index (DLQI) questionnaire on 100 acne patients 15 years and above, in a tertiary care hospital. Interpretation of score and impact on quality of life (QoL) was done and graded as no effect, small effect, moderate effect, and very large effect.<strong></strong></p><p class="abstract"><strong>Results:</strong> In our study, females outnumbered males (M: F ratio=1: 1.22). The age group most affected was within 15 and 20 years of age. The mean DLQI score was 5.59±4.07. Most of them had a ‘small impact’ on the QoL. QoL was worse in females. The most common grade of acne overall was grade 2 acne. Grade 3 acne was more common in men. Most of the patients (84%) experienced some degree of embarrassment or increased self-consciousness due to their acne.</p><p class="abstract"><strong>Conclusions:</strong> Our study showed significant impairment of QoL in acne patients. Treatment of acne should not be guided only by the clinical grade of acne, but take into consideration the psychosocial impact the condition has on the patient. Adequate counselling along with early treatment of acne vulgaris is essential in order to reduce the disease-related psychosocial sequelae and increase treatment efficacy.</p>

scholarly journals Epidemiological charactristics of acute hepatitis in tertiary care hospital.

2021 ◽  
Vol 28 (7) ◽  
pp. 1039-1043
Author(s):  
Hafiz Mughees Ather ◽  
◽  
Arfan Mahmood ◽  
Affan Shahid ◽  
Mohammed Osama ◽  
...  
Keyword(s):  
Acute Hepatitis ◽  
Tertiary Care ◽  
Stable Condition ◽  
Water Source ◽  
Categorical Variables ◽  
P Value ◽  
Common Symptom ◽  
Care Hospital ◽  
Cross Sectional ◽  
Epidemiological Characteristics

Objective: To record the epidemiological, characteristics of Acute hepatitis patients. Study Design. Cross Sectional study. Setting: Government General Hospital Ghulam Muhammad Abad, Faisalabad. Period: March 2019 to 30th of September 2019. Material & Methods: A total of 92 patients included in the study. Patient’s epidemiological characteristics, symptoms and lab results were recorded during hospital stay. Categorical variables were analyzed using Chi-Square and Fissure Exact tests. P value of <0.05 was considered statistically significant. Results: 78% were male & 22% were female. Water source was 16% filtered water, 32% ground water & 52% was Government supplied water. Most common symptom was yellow sclera (100%), Dark urine (100%), Nausea, fatigue and anorexia (Each 87%), Vomiting (83%), Fever (73%), Right hypochondriac pain (70%), Body aches (66%) and headache was 61%. Among the risk factors other than water source, outside eating was present in 74% and tattooing was present in 5% while blood transfusion history and Ear/Nose piercing was 0%. All 92 patients discharged in stable condition (100%). Tests for determination of cause i.e HAV & HEV serology were ordered in each case. Conclusion: Young males were affected more commonly. Presentation of acute hepatitis varies in symptoms but mostly the disease is self-limiting and running a mild course without leading to liver failure. Most common risk factor was outside eating in unhygienic environment which should be avoided.

scholarly journals Cross-sectional study of quality of life impairment of adult female acne patients

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Ehiaghe L Anaba ◽  
Motunsope Olufolakemi Cole-Adeife
Keyword(s):  
Quality Of Life ◽  
Adult Female ◽  
Statistical Tests ◽  
Acne Vulgaris ◽  
Cross Sectional Study ◽  
Categorical Variables ◽  
Sectional Study ◽  
Cross Sectional ◽  
Adult Females

The effect of acne vulgaris on the quality of life of adult females is not readily documented nor the factors that impair quality of life in these adult females. The aim of this study was to document quality of life impairment and the factors that affect this quality of life in adult female acne patients. The study was a prospective cross sectional study of 56 adult female acne patients aged 25 years and above. Socio-demographic data, clinical examination were documented with a study proforma. Quality of life was assessed using Cardiff Acne Disability Index (CADI). Data was analysed using SPSS version 22. Mean of independent groups were compared using Students ‘t’ test while Chi squared test was used to compare categorical variables. For all statistical tests, P value <0.05 was adjudged to be significant. The mean age of the participants was 33.4± 8.2 and mean CADI was 6.6±3.8, minimum CADI was 2 and maximum was 15. Quality of life impairment was mild, moderate and severe in 35.7%, 37.5% and 26.8% respectively. The items affected in the CADI index were questions about “Perception of how bad pimples were,” “Feelings about appearance of skin,” and “Aggression, frustration and embarrassment.” Factors associated with quality of life impairment were age, post inflammatory hyperpigmentation, presence of scarring. Quality of life is impaired by acne in adult females. This impairment is made worse by age, presence of scarring and post-inflammatory hyperpigmentation and not marital status, level of education and a family history of acne.

scholarly journals A Study on the Clinical and Hormonal Profile of Polycystic Ovarian Syndrome Patients Attending a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2020 ◽  
Vol 58 (231) ◽  
Author(s):  
Achala Vaidya ◽  
Sweta Yadav ◽  
Anshu Vaidya
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Care Hospital ◽  
Women Of Reproductive Age ◽  
Cross Sectional ◽  
Hormonal Profile ◽  
Ovarian Syndrome

Introduction: Polycystic ovarian syndrome (PCOS) is the most common endocrinological disorder in women of reproductive age and has a considerable metabolic, reproductive, and cardiovascular consequences. This study was designed to provide an overview of the presentation of PCOS in the Nepalese population attending a tertiary care hospital, specifically the clinical presentation and hormonal profile. Methods: A descriptive cross-sectional study was conducted between September 14, 2019 to October 16, 2019 on patients presenting to a tertiary care hospital, after obtaining ethical clearance from Institutional Review Committee (Dated 03/09/2019) and informed consent from the patient or patient relatives. Data entry and analysis were done in Microsoft Excel 10. The data was statistically analysed using Statistical Package for the Social Sciences (SPSS) version 20.0. Results: The study included 100 PCOS patients. The mean age of the patients was 24.9 ± 4.52 years and the most common group was 26-34 years. The most common presenting symptom was menstrual irregularity which was seen in 86 (86%) of the patients, followed by weight gain in 55 (55%) of the patients. Thirty percent (30 in number) of the patients were overweight, while eleven (11%) of the patients had grade I obesity. Conclusions: PCOS has varying clinical manifestations, most commonly affecting the young women of reproductive age group. The commonest presenting complaint in the current study was menstrual abnormality. Majority of the patients had deranged hormonal profile which can lead to an increased risk of cardiovascular disease and type 2 DM. Thus, awareness regarding PCOS is important for early diagnosis and to prevent its sequalae to various complications.

scholarly journals Recurrent Bacteria Involvement in Urinary Tract Infection among Diabetic Female Patients of Sukkur, Sindh

2021 ◽  
pp. 229-234
Author(s):  
Samina Tarique ◽  
Abdul Hussain Shar ◽  
Syed Fiaz Hussain ◽  
Akhtar Ali
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Tertiary Care ◽  
P Value ◽  
Care Hospital ◽  
Cross Sectional ◽  
E Coli ◽  
Female Patients ◽  
Significant Difference

Background: Diabetics are four times more prone to develop Urinary tract infection when compared to healthy individuals, the proposed risk factors behind this increase in susceptibility in diabetics are autonomic neuropathy resulting in incomplete emptying of bladder and glucose in urine which serves as a medium for bacterial growth. The aims of our study are to identify the frequency of recurrent UTI and to document most common prevalent organisms involved in UTI in diabetic females in tertiary care hospital of Sukkur. Methodology: It was a cross sectional study conducted at Microbiology Department of Shah Abdul Latif University Khairpur from January to December 2020. The sample size n=54 was calculated by open epi software. Participants who contented inclusion criteria i.e., female patients of age >18 years with diabetes mellitus for more than 5 years who were presented in OPD with UTI along with history of three positive urine cultures in the previous 12 months or two episodes in the last six months were recruited by simple random sampling technique. The urine samples were collected in sterile containers and the growth of organisms was observed on nutrient agar and MacConkey agar plates. Results: There was no any significant difference among occurrence of bacteria between both the groups i.e . However, the most associated microbes with uncontrolled HbA1c profile were E. coli (p-value = 0.004) followed by Micrococcus lutes (p-value = 0.021) and Shigella (p-value = 0.001).  Table 1. Shows the frequency and percentages of bacteria associated with controlled and uncontrolled HbA1c levels. Conclusion: Most of the participants had uncontrolled diabetic profile i.e. HbA1c > 7, the prominent pathogen at our setting were E. Coli, Enterococcus species, Shigella species and Micrococcus lutes.

Evaluation of Prescription Pattern and Quality of life in Acne in Tertiary Care Hospital in North Indian population

2017 ◽  
Vol 3 (4) ◽  
pp. 392-400
Author(s):  
Nalini Negi ◽  
Sumir Kumar ◽  
Sourabh Kosey ◽  
Vir Vikram Sharma
Keyword(s):  
Quality Of Life ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
North India ◽  
Grading System ◽  
Care Hospital ◽  
Cross Sectional ◽  
Prescription Pattern ◽  
Severity Of The Disease

Objective: The aim of this study was to evaluate the prescription pattern and Quality of Life of patients and severity of the disease by using Cardiff Acne Disability Index and Global Acne Grading System score respectively. Methods: A cross-sectional study was conducted in North India with 150 samples of patients included into the study. The prescription pattern comprehends the information about the prescribed drugs and also their dosing pattern for different indications that are currently being used in clinical practice. The prescription pattern varies according to the severity of the disease. Results: The cases in the study diagnosed were mostly of acne vulgaris (96.7%), followed by acne conglobata (1.3%), acne rosaceae (1.3%) and acne fulminans (0.7%). Conclusion: It was noted that oral Isotretinoin was the drug of choice for the treatment of moderate and severe forms and antibiotics included into the therapy were minocycline, clindamycin, azithromycin and erythromycin for mild and severe forms. There was not a strong degree of association between therapy and improvement in Cardiff Acne Disability Index and Global Acne Grading System but by observing overall Cardiff Acne Disability Index improvement it can be estimated that the prescription practice used for therapy enhances Quality of Life of the patient.

scholarly journals Pattern of acne vulgaris in women, attending in a tertiary care hospital

2012 ◽  
Vol 18 (1) ◽  
pp. 18-23
Author(s):  
L Khondker ◽  
MM Rahman ◽  
MM Mahmud ◽  
MSI Khan ◽  
H Khan ◽  
...  
Keyword(s):  
Acne Vulgaris ◽  
Tertiary Care ◽  
Study Finding ◽  
Epidemiological Studies ◽  
Cross Sectional Study ◽  
Large Sample Size ◽  
Care Hospital ◽  
Cross Sectional ◽  
The Mean ◽  
Meta Analyses

A cross-sectional study was carried out for a period of one year in the outpatient department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh. Seventy female patients having acne vulgaris were selected. The study showed that the mean age of the cases was 22.43 with standard deviation 5.2 years and highest percentage of patients were in the age group 20-24 years (41.4%), highest percentage of patients was unmarried among the cases (74.3%) and proportion of secondary (35.7%) and higher secondary education (20%) were found to be high among the cases. The study showed that proportion of student (65.7%) and housewife (17.1%) were found to be high among the cases. The mean duration of disease was 62.6 months and all the patients had presented with comedones (blackheads and whiteheads). All the patients had acne in the face and it was found that 60% had moderate type acne. Considering the pattern of treatment received, 42.9% of the patients mentioned that they used topical ointment, 37.1% had received herbal medication and 25.7% had received systemic medication. To get an overall impression of the country regarding acne vulgaris, more integrated study is needed. This was a study on a limited number of cases. Future studies must include economical support, then large sample size could be ensured and study finding would be more reliable. There is a great need of epidemiological studies also, with sufficient follow-up, systematic reviews and meta-analyses on this issue. DOI: http://dx.doi.org/10.3329/jdnmch.v18i1.12234 J. Dhaka National Med. Coll. Hos. 2012; 18 (01): 18-23

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