scholarly journals Effects of Kinesio Taping in Supraspinatus Tendinitis

2021 ◽  
Vol 5 (6) ◽  
pp. 67-71
Author(s):  
Jawad Anwar ◽  
Farjad Afzal ◽  
Muhammad Mustafa Qamar ◽  
Ayesha Basharat
Keyword(s):  
Shoulder Pain ◽  
Rating Scale ◽  
Post Treatment ◽  
Mean Difference ◽  
Dash Score ◽  
Kinesio Taping ◽  
Musculoskeletal Problems ◽  
Effective Program ◽  
Pre Treatment ◽  
Supraspinatus Tendinitis

Background: Shoulder pain is one of the most commonly reported musculoskeletal problems after low back pain. One common reason for the shoulder pain is supraspinatus tendinitis that is often associated with impingement syndrome. Objective: To find the effects of kinesio taping in reducing pain and disability in subjects with supraspinatus tendinitis. Methodology: In this study, patients were randomly allocated the treatment using a set of predefined inclusion and exclusion criteria. Subjects were managed with kinesio taping. Pre- and post-evaluation of the patients was done using Numerical Pain Rating Scale (NPRS) and Disability of Arm Shoulder & Hand Questionnaire (DASH) score and the data gathered was entered and analyzed using SPSS version 23. Results: Mean difference of 2.65 was reported between the pretreatment and post treatment values of NPRS in KT taping group which was significant (P < 0.05). Mean difference of 27.25 was reported between the pre-treatment and post-treatment values of DASH score in KT taping group which was significant (P < 0.05). Conclusion: Kinesio taping is an effective Program in management of supraspinatus tendinitis.

Effectiveness and safety of extracorporeal shock wave treatment for low back pain:a systematic review and meta-analysis of RCTs

2020 ◽  
Author(s):  
Jinhui Ma ◽  
Yan Yan ◽  
Bailiang Wang ◽  
Wei Sun ◽  
Debo Yue ◽  
...  
Keyword(s):  
Shock Wave ◽  
Rating Scale ◽  
Meta Analysis ◽  
Post Treatment ◽  
Mean Difference ◽  
Control Group ◽  
Low Back ◽  
China National Knowledge Infrastructure ◽  
Pain Scores ◽  
Extracorporeal Shock Wave

Abstract Background Extracorporeal shock wave therapy (ESWT) has been widely used in musculoskeletal disorders. This meta-analysis was designed to assess the effectiveness and safety of ESWT for patients with low back pain (LBP). Methods Multiple electronic databases including Pubmed, Embase, Cochrane’s library, China National Knowledge Infrastructure (CNKI), and Wanfang Data were searched until December, 2019 to identify studies assessing the effectiveness and safety of EPSW for LBP. The prime outcome is pain intensity measured by Visual Analog Scale (VAS) or numeric rating scale (NRS). Other outcomes included functional status, quality of life, psychological outcomes measured by Oswestry Disability Index (ODI), as well as the adverse events. Mean differences were calculated for continuous outcomes, while odd ratios were calculated for binary outcomes. Revman 5.3 software was used for statistical analysis. Results Five randomized controlled trials (RCTs) were finally included in this meta-analysis. The pooled mean difference in post-treatment pain scores was −2.37 (P <0.0001), indicating that post-treatment pain scores was significantly higher by 2.37 in control group than in ESWT group. At a mean follow-up time of 4-6 weeks, the pooled mean difference in ODI scores was −14.10 (P <0.00001), indicating that the pooled mean difference of post-treatment ODI scores was 14.10 higher in control group than in ESWT group. Conclusions The use of focused ESWT is effective in alleviating pain and improving the general fuctional state for patients with LBP. However, more evidence was needed to verify its safety.

scholarly journals Guided self-help concreteness training as an intervention for major depression in primary care: a Phase II randomized controlled trial

2011 ◽  
Vol 42 (7) ◽  
pp. 1359-1371 ◽  
Author(s):  
E. R. Watkins ◽  
R. S. Taylor ◽  
R. Byng ◽  
C. Baeyens ◽  
R. Read ◽  
...  
Keyword(s):  
Primary Care ◽  
Major Depression ◽  
Cognitive Processes ◽  
Relaxation Training ◽  
Rating Scale ◽  
Controlled Trial ◽  
Post Treatment ◽  
Mean Difference ◽  
Treatment As Usual ◽  
Self Help

BackgroundThe development of widely accessible, effective psychological interventions for depression is a priority. This randomized trial provides the first controlled data on an innovative cognitive bias modification (CBM) training guided self-help intervention for depression.MethodOne hundred and twenty-one consecutively recruited participants meeting criteria for current major depression were randomly allocated to treatment as usual (TAU) or to TAU plus concreteness training (CNT) guided self-help or to TAU plus relaxation training (RT) guided self-help. CNT involved repeated practice at mental exercises designed to switch patients from an unhelpful abstract thinking habit to a helpful concrete thinking habit, thereby targeting depressogenic cognitive processes (rumination, overgeneralization).ResultsThe addition of CNT to TAU significantly improved depressive symptoms at post-treatment [mean difference on the Hamilton Rating Scale for Depression (HAMD) 4.28, 95% confidence interval (CI) 1.29–7.26], 3- and 6-month follow-ups, and for rumination and overgeneralization post-treatment. There was no difference in the reduction of symptoms between CNT and RT (mean difference on the HAMD 1.98, 95% CI −1.14 to 5.11), although CNT significantly reduced rumination and overgeneralization relative to RT post-treatment, suggesting a specific benefit on these cognitive processes.ConclusionsThis study provides preliminary evidence that CNT guided self-help may be a useful addition to TAU in treating major depression in primary care, although the effect was not significantly different from an existing active treatment (RT) matched for structural and common factors. Because of its relative brevity and distinct format, it may have value as an additional innovative approach to increase the accessibility of treatment choices for depression.

scholarly journals EFFECTIVENESS OF INDIVIDUALIZED APPROACH FOR PHYSIOTHERAPY OF CHRONIC SHOULDER PAIN AND PHYSICAL FUNCTIONING IN ELITE ATHLETES WITH PHYSICAL DISABILITIES

2020 ◽  
Vol 2 (2020) ◽  
pp. 91-106
Author(s):  
Martin Eremiev ◽  
◽  
Bobi Krumov ◽  
Irena Lyudmilova ◽  
Nadezhda Popova ◽  
...  
Keyword(s):  
Shoulder Pain ◽  
Rating Scale ◽  
Scratch Test ◽  
Shoulder Girdle ◽  
Post Treatment ◽  
Wheelchair Athletes ◽  
Shoulder Flexion ◽  
The Right ◽  
Outcome Rating Scale ◽  
Chronic Shoulder Pain

ABSTRACT Objective: Тo study the potential effectiveness of individual physiotherapy program for wheelchair athletes with shoulder girdle persistent pain and dysfunctions. Materials and methods: Thirteen athletes, members of the Bulgarian National Teams in wheelchair basketball and track and field athletics, with mean age 40.6 ± 10.9 participated in the study. The studied athletes had had a history of persistent pain and shoulder girdle dysfunctions for more than 6 months. Individual physiotherapy programs were applied to the participants for a period of two weeks. The selection of techniques was based on the initial assessment and evaluation. The participants were evaluated before treatment, after the first week of treatment, and at the end of the period with the use of the following specific questionnaires and tests: Goniometry of shoulder flexion and horizontal adduction, Apley’s Scratch test, Active compression test of O’Brien (ACT), Athletic shoulder outcome rating scale and Wheelchair User’s Shoulder Pain Index (WUSPI). Results: Post-treatment effects demonstrated a significant (p<0.05) increase in shoulder flexion (14.6° for the right and 12.7° for the left) and horizontal adduction (21.9° for the right and 18.8° for the left). A corresponding increase in the scores for the Athletic shoulder outcome rating scale was found with 10.92 points difference to the initial score (p<0.05). The WUSPI demonstrated a non-significant improvement of 0.69 points. The results of ACT and Apley scratch test showed a non-significant decrease of 23.1% for the right shoulder and, 15.4% decrease for the left shoulder after 7 days of treatment. Those results remained unchanged in post-treatment testing. Conclusion: This study showed that the individual physiotherapy programs are effective in the management of wheelchair athletes with chronic shoulder pain. The involvement of Mulligan’s manual therapy techniques combined with other types of exercises for the shoulder and the trunk are beneficial for wheelchair athletes with chronic shoulder pain.

Effects of Minimal Acupuncture in Children with Infantile Colic – a Prospective, Quasi-Randomised Single Blind Controlled Trial

2008 ◽  
Vol 26 (3) ◽  
pp. 171-182 ◽  
Author(s):  
Marianne Reinthal ◽  
Sven Andersson ◽  
Marianne Gustafsson ◽  
Kaety Plos ◽  
Iréne Lund ◽  
...  
Keyword(s):  
Side Effects ◽  
Rating Scale ◽  
Controlled Trial ◽  
Numeric Rating Scale ◽  
Post Treatment ◽  
Control Group ◽  
Seek Health Care ◽  
Parental Assessment ◽  
The Difference ◽  
Pre Treatment

Background Colic causes crying in 10–30% of infants and is one of the primary reasons parents seek health care. Treatments are generally not totally effective and some cause side effects. In this study we aimed to test the effect of light needling (minimal acupuncture) on crying. Methods Forty children (median six weeks of age) with excessive crying unresponsive to conventional therapies, were recruited from 21 Child Welfare Clinics within an area of western Sweden, and quasi-randomised to control or light needling treatment. Parents were unaware of which group their child was assigned to. Children were given light needling acupuncture on one point (LI4) on both hands for approximately 20 seconds on four occasions, or received the same care except needling. Parental assessment questionnaires were used pre- and post-treatment to assess crying intensity, frequency, duration of crying and pain related behaviour throughout the day in six hour periods. Results Light needling resulted in a significant reduction in the rated crying intensity (assessed by a numeric rating scale, 0 to 10). For example, during the morning time period 0600–1200 hours, the median (range) rated crying intensity changed from 6 (1 to 9) pre-treatment to 2 (0 to 5) post-treatment (P=0.002), in the light needling group. The corresponding ratings for the children in the control group was 6 (0 to 10) and 5 (0 to 10) respectively. The difference between the groups was significant (P=0.016). There were also significant differences between the groups for the afternoon (1200–1800 hours), and evening (1800–midnight) time periods. Pain related behaviour like facial expression, was also significantly less pronounced in the light needling group as compared to the control group post-treatment, (P=0.027). The parents rated the light needling as more effective in improving symptoms than the control group (P<0.001). Conclusion Four treatments with light needling on one point in the hand may alleviate crying and pain related behaviour without any noted side effects.

Neurobiological Basis of Reinforcement-Based Decision-Making in Adults With ADHD Treated With Lisdexamfetamine Dimesylate

2021 ◽  
Vol 25 (11) ◽  
pp. 1632-1633
Author(s):  
I. Ivanov ◽  
J. H. Newcorn ◽  
B. Krone ◽  
X. Li ◽  
S. Duhoux ◽  
...  
Keyword(s):  
Prediction Error ◽  
Rating Scale ◽  
Reward Processing ◽  
Post Treatment ◽  
Symptom Improvement ◽  
Adhd Symptoms ◽  
Lisdexamfetamine Dimesylate ◽  
Brain Reward ◽  
Pre Treatment ◽  
The Brain

Background: The objective of this study was to examine changes in the activation of the brain reward system following treatment with lisdexamfetamine (LDX) vs. placebo (PL) as a function of clinical improvement in attention deficit/hyperactivity disorder (ADHD) symptoms. Methods: Twenty adults with ADHD were included in a randomized cross-over study. Participants underwent two functional magnetic resonance imaging (fMRI) scans, after receiving 3 to 5 weeks of treatment with both LDX and PL. During scanning, participants performed the passive-avoidance learning task to assess reward-related learning using computational variables (e.g., estimated value and prediction error). Pre-treatment to post-treatment symptom change was assessed via the ADHD Rating Scale (ADHD-RS). The imaging contrasts were Object Choose or Object Refuse during the object choice component of the task, modulated by expected value (reward vs. nonreward cue), and Reward vs. Punishment during feedback, modulated by prediction error (expected vs. actual outcome). To address the primary objective, we performed group-level mass univariate analyses between pre-treatment to post-treatment percent change of the ADHD-RS total scores and the four contrast images under the choice and feedback conditions, with significance set at a whole-brain voxel-wise threshold of p < .05 with family-wise error (FWE) correction and an extent (cluster) threshold of 50 contiguous voxels. Results: Improvement in ADHD symptoms was accompanied by significant increases of brain activation during the Object Refuse, Reward and Punishment contrasts in a widespread network including left caudate and putamen, and right orbitofrontal cortex (i.e., reward-related signaling) and left middle frontal, superior frontal, and precentral gyri (i.e., executive control). Conclusions: These findings are the first to show that the increase in responsiveness of systems engaged in reward processing with LDX treatment is positively related to symptom improvement. Results support the hypothesis that LDX treatment may restore balance to dysfunction (e.g., hypoactivation) within the brain reward circuitry in adults with ADHD.

scholarly journals An initial exploration of hair cortisol responses to antidepressants in unmedicated patients with depression

2019 ◽  
Vol 48 (3) ◽  
pp. 030006051988943 ◽  
Author(s):  
Xiuli Song ◽  
Wei Cui ◽  
Zugui Peng ◽  
Liansheng Zhao ◽  
Xuezhu Yu ◽  
...  
Keyword(s):  
Hpa Axis ◽  
Rating Scale ◽  
Cortisol Concentration ◽  
Post Treatment ◽  
Hair Cortisol ◽  
Long Term Effects ◽  
Scale Scores ◽  
Healthy Control ◽  
Cortisol Responses ◽  
Pre Treatment

Objective Major depressive disorder is associated with abnormal functioning of the hypothalamic–pituitary–adrenal (HPA) axis. Studies using hair cortisol to measure the effect of antidepressants on the HPA axis are lacking. The aim of this study was to explore the long-term effects of antidepressants on hair cortisol concentration (HCC). Methods Participants were 42 patients and 36 healthy individuals. The patients took antidepressants for 4 weeks. Patient HCC was measured pre-treatment and post-treatment. The HCC of healthy controls was also measured. Results Patient post-treatment HCC (mean ± standard deviation: 34.40 ± 32.57 pmol/mg) was significantly higher than patient pre-treatment HCC (17.42 ± 12.40 pmol/mg) and healthy control HCC (10.22 ± 7.99 pmol/mg). No significant correlation was found between Hamilton Depression Rating Scale scores and HCC at pre-treatment or post-treatment. Conclusions Hair cortisol concentration analysis could be used to monitor the dynamics of the effects of antidepressants on the HPA axis.

Cytoprotective Effect of Tocotrienol-Rich Fraction and α-Tocopherol Vitamin E Isoforms Against Glutamate-Induced Cell Death in Neuronal Cells

2014 ◽  
Vol 84 (3-4) ◽  
pp. 0140-0151 ◽  
Author(s):  
Thilaga Rati Selvaraju ◽  
Huzwah Khaza’ai ◽  
Sharmili Vidyadaran ◽  
Mohd Sokhini Abd Mutalib ◽  
Vasudevan Ramachandran ◽  
...  
Keyword(s):  
Vitamin E ◽  
Cell Viability ◽  
Neuronal Cells ◽  
Positive Control ◽  
Post Treatment ◽  
Mitochondrial Activity ◽  
Before And After ◽  
Pre Treatment ◽  
Tocotrienol Rich Fraction ◽  
Major Mediator

Glutamate is the major mediator of excitatory signals in the mammalian central nervous system. Extreme amounts of glutamate in the extracellular spaces can lead to numerous neurodegenerative diseases. We aimed to clarify the potential of the following vitamin E isomers, tocotrienol-rich fraction (TRF) and α-tocopherol (α-TCP), as potent neuroprotective agents against glutamate-induced injury in neuronal SK-N-SH cells. Cells were treated before and after glutamate injury (pre- and post-treatment, respectively) with 100 - 300 ng/ml TRF/α-TCP. Exposure to 120 mM glutamate significantly reduced cell viability to 76 % and 79 % in the pre- and post-treatment studies, respectively; however, pre- and post-treatment with TRF/α-TCP attenuated the cytotoxic effect of glutamate. Compared to the positive control (glutamate-injured cells not treated with TRF/α-TCP), pre-treatment with 100, 200, and 300 ng/ml TRF significantly improved cell viability following glutamate injury to 95.2 %, 95.0 %, and 95.6 %, respectively (p < 0.05).The isomers not only conferred neuroprotection by enhancing mitochondrial activity and depleting free radical production, but also increased cell viability and recovery upon glutamate insult. Our results suggest that vitamin E has potent antioxidant potential for protecting against glutamate injury and recovering glutamate-injured neuronal cells. Our findings also indicate that both TRF and α-TCP could play key roles as anti-apoptotic agents with neuroprotective properties.

CONTRACEPTION BY AN INJECTABLE LONG-ACTING OESTROGEN-PROGESTOGEN AGENT. III

1972 ◽  
Vol 69 (1) ◽  
pp. 67-76
Author(s):  
Rolf Plesner
Keyword(s):  
Treatment Period ◽  
Treatment Cycle ◽  
Post Treatment ◽  
Mixed Phase ◽  
Discontinuation Of Treatment ◽  
Phase Type ◽  
Secretory Type ◽  
Pre Treatment ◽  
Long Acting ◽  
Fertile Women

ABSTRACT Twenty-two fertile women were treated cyclically in from 4–30 cycles (mean 15.5) with a total of 341 injections of Deladroxate®, an injectable, long-acting oestrogen-progestogen. The injections were administered on the 8th (7th–9th) day of each cycle. Before treatment, the last pre-treatment cycle was controlled by means of daily recordings of the basal body temperature (BBT), urinary excretion of pregnanediol and total pituitary gonadotrophins at certain intervals, and by endometrial biopsies obtained late in the cycle. The effects of Deladroxate® on ovulation, on pituitary gonadotrophic function, and on the endometrium were controlled by the above mentioned parameters during cycles 1, 3, and 6, and all assessments were repeated after discontinuation of treatment. During treatment, there was a statistically significant fall in gonadotrophin excretion values (as compared with the pre-treatment values), and the fall was found to be gradually progressive during treatment. After discontinuation of treatment, there seemed to be a tendency towards an increase in the excretion values. Suppression of ovulation as determined by means of the pregnanediol excretion during treatment, was effective in nearly all of the treatment cycles checked. The fall in pregnanediol excretion was also gradually progressive during treatment, while there was a slight increase in excretion values in the post-treatment period. During treatment, 79 BBT curves were recorded. Nearly 50 % were monophasic, indicating anovulatory cycles, 17 curves were biphasic, but with the rise in temperature occurring at non-characteristic times in the cycles, 18 curves were classified as thermogenic because of a rise in temperature occurring within 24 hours after the injection, and 5 curves were not assessable. During the first month after discontinuation of treatment, 8 out of 10 recorded curves were monophasic. Out of 53 endometrial biopsies obtained around the 23rd day of the cycle, 31 were of the mixed phase type, but showing a predominance of proliferative patterns, 15 were of the secretory type, and 7 were purely proliferative. Out of 15 biopsies obtained in the post-treatment period, only two were of the mixed phase type, 12 were proliferative and one was purely secretory.

Pre-treatment and post-treatment visual functions in congenital myopia alone versus congenital myopia complicated by amblyopia

2018 ◽  
Vol 75 (4) ◽  
pp. 44-48
Author(s):  
A. Mukhina ◽  
◽  
I. Boichuk ◽  
L. Zhuravliova ◽  
◽  
...  
Keyword(s):  
Post Treatment ◽  
Visual Functions ◽  
Pre Treatment

scholarly journals Relationship between metamorphopsia and inner retinal microstructure following intravitreal ranibizumab injection for branch retinal vein occlusion

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yoshimi Sugiura ◽  
Fumiki Okamoto ◽  
Tomoya Murakami ◽  
Shohei Morikawa ◽  
Takahiro Hiraoka ◽  
...  
Keyword(s):  
Macular Edema ◽  
Retinal Vein Occlusion ◽  
Branch Retinal Vein Occlusion ◽  
Post Treatment ◽  
Intravitreal Ranibizumab ◽  
Vein Occlusion ◽  
Treatment Naïve ◽  
Pre Treatment ◽  
Number Of Injections

AbstractTo evaluate the effects of intravitreal ranibizumab injection (IVR) on metamorphopsia in patients with branch retinal vein occlusion (BRVO), and to assess the relationship between metamorphopsia and inner retinal microstructure and other factors. Thirty-three treatment-naïve eyes of 33 patients with macular edema caused by BRVO with at least 12 months of follow-up were included. The degree of metamorphopsia was quantified using the M-CHARTS. Retinal microstructure was assessed with spectral-domain optical coherence tomography. Disorganization of the retinal inner layers (DRIL) at the first month after resolution of the macular edema (early DRIL) and at 12 months after treatment (after DRIL) was studied. Central retinal thickness (CRT), and status of the external limiting membrane as well as ellipsoid zone were also evaluated. IVR treatment significantly improved best-corrected visual acuity (BCVA) and CRT, but the mean metamorphopsia score did not improve even after 12 months. Post-treatment metamorphopsia scores showed a significant correlation with pre-treatment metamorphopsia scores (P < 0.005), the extent of early DRIL (P < 0.05) and after DRIL (P < 0.05), and the number of injections (P < 0.05). Multivariate analysis revealed that the post-treatment mean metamorphopsia score was significantly correlated with the pre-treatment mean metamorphopsia score (P < 0.05). IVR treatment significantly improved BCVA and CRT, but not metamorphopsia. Post-treatment metamorphopsia scores were significantly associated with pre-treatment metamorphopsia scores, the extent of DRIL, and the number of injections. Prognostic factor of metamorphopsia was the degree of pre-treatment metamorphopsia.

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