scholarly journals COVID-19 infection mortality risk in Iranian patients with type 2 diabetes, hypertension and obesity

Author(s):  
Mahdi Shadnoush ◽  
Soghra Rabizadeh ◽  
Alireza Esteghamati ◽  
Manouchehr Nakhjavani ◽  
Nasrin Baiat Paridari ◽  
...  

Background: Diabetes mellitus and hypertension are highly prevalent among patients with severe COVID-19. Aims: To study mortality risk of COVID-19 infection in patients with type 2 diabetes and additive effect of hypertension and obesity in the Iranian population. Methods: This was a cross-sectional survey of the national COVID-19 registry from the Iranian Ministry of Health. The medical status of 22 002 patients with COVID-19 between 1 March and 30 April 2020 was analysed. Results: Patients with type 2 diabetes had a higher risk of mortality with an odds ratio (OR) of 1.67 [95% confidence interval (CI): 1.53–1.82, P < 0.001]. The risk of mortality was also higher in patients with diabetes and hypertension, with an odds ratio of 1.76 (95% CI: 1.56–1.99, P < 0.001). The odds ratio of the risk of mortality in patients with diabetes, hypertension and obesity was 1.87 (95% CI: 1.35–2.58, P < 0.001). Conclusion: Type 2 diabetes, hypertension and obesity each predict mortality in Iranian patients with COVID-19, and when they are present together, patients have a greater risk of mortality.

Author(s):  
Yieng Yii Wong ◽  
Azizul Hakim Sulaiman ◽  
Anis Aeida Mat Jaya ◽  
Pei Zan Wan ◽  
Anchaya Eh Wan ◽  
...  

Current global estimates of traditional and complementary medicine (T&CM) utilization range from 9.8% to 76%, with high rates of use being documented in Japan, South Korea, and Malaysia. Previous research has shown that patients with diabetes are more likely to use T&CM than individuals without diabetes. A multicenter cross-sectional survey of patients with type 2 diabetes mellitus was conducted at five primary care health clinics in Petaling district of Selangor, Malaysia from June 1, 2020 through September 30, 2020. A total of 476 patients were enrolled. 58.0% of men and 64.8% of women reported to use at least a type of T&CM. The prevalence of T&CM use among Malays, Chinese, and Indians was 71.1%, 33.3%, and 62.9% respectively. The most commonly used T&CM were herbal remedies (45.2%), followed by nutritional supplements (9.9%). 80.0% of the patients would follow their doctor’s instruction if the doctor asked them not to use T&CM, whereas 70.2% would consult their doctor about using T&CM. Factors associated with higher tendency for T&CM use comprised increased age, unemployed, oral antidiabetic monotherapy, presence of family history of diabetes, and coexisting chronic disease. T&CM therapies were common among multi-ethnic patient population with type 2 diabetes. The high rate of use warranted clinical attention and intervention to reduce the risk of drug-associated adverse events.


F1000Research ◽  
2015 ◽  
Vol 4 ◽  
pp. 7 ◽  
Author(s):  
Eduardo De la Cruz-Cano ◽  
Carlos Alfonso Tovilla-Zarate ◽  
Emilio Reyes-Ramos ◽  
Thelma Beatriz Gonzalez-Castro ◽  
Isela Juarez-Castro ◽  
...  

Background: Diabetes mellitus and depression are highly prevalent conditions throughout the world and have significant impact on health outcomes. It has been estimated that diabetes mellitus type 2 affects about 246 million people in the world; nevertheless, incidence varies among countries. There is evidence that depression is associated with a poor metabolic control in patients with type 2 diabetes mellitus that present other health problems (such as hypertension and obesity). The aim of this study protocol is to determine if obesity increases the risk for depression in patient with diabetes type 2.Methods: The analysis will be reported following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).The studies suitable for inclusion will be assessed by the Newcastle-Ottawa Scale (NOS) to determine their methodological quality. To identify the studies of interest, we will search on PubMed and EBSCO databases. We will use the following keyword combinations: "Diabetes Mellitus type 2 AND obesity AND depression", "depression AND Diabetes Mellitus type 2", "Diabetes Mellitus type 2 AND body mass index cross sectional study", "depression AND obesity cross-sectional study". Causes for exclusion will be publications that studied patients diagnosed with diabetes mellitus type 1; articles that focused on the treatment and complications of diabetes mellitus type 2; publications that have studied other clinical or psychiatric conditions (for instance, seizure disorder or history of schizophrenia, bipolar disorder, psychotic symptoms or dementia).Conclusion: The results of this study will form the basis for a better understanding of the association between obesity and depression in patients with diabetes mellitus type 2, and will allow development of prediction tools and better interventions. It is evident that several modifiable and non-modifiable risk factors play an important role in the pathogenesis of diabetes among population. Currently, evidence for the deleterious effects of diabetes mellitus type 2 are based on cross-sectional or other observational designs. Therefore, this study will have important implications for future research and public health guidance.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Mayumi Matsunaga ◽  
Yaeko Kataoka ◽  
Yumiko Igarashi ◽  
Toshiko Fukui ◽  
Masumi Imura ◽  
...  

Abstract Background Despite the benefits of breastfeeding for women with Gestational Diabetes Mellitus (GDM) and their infants, breastfeeding is less likely to be performed by this group. This study aimed to examine the current levels of implementation of breastfeeding support to women with GDM in Japan and to clarify barriers to promoting breastfeeding among this population. Methods A 25-item questionnaire was developed by the authors to investigate the current levels of implementation of breastfeeding support for women with GDM provided in hospitals, and to explore barriers for promoting breastfeeding among these women. The questionnaire was sent to all 1046 hospitals facilitating childbirth in Japan. Descriptive statistics were used to analyze the quantitative data, and content analysis was used to analyze qualitative data from the open-ended questions. Results All 296 respondents were included in this study. Regarding breastfeeding support, 95.2% of the respondents provided general information on breastfeeding to GDM women during antenatal midwife consultations. However, the benefits of breastfeeding for preventing type 2 diabetes were addressed by only 48.0%. Likewise, although follow-up services (e.g., telephone support or breastfeeding consultations) were conducted in 88.9% of hospitals, only 50.7% of hospitals informed women that breastfeeding decreases the risk of developing type 2 diabetes after GDM. Regarding barriers, seven categories and 20 subcategories about promoting breastfeeding for women with GDM were extracted and abstracted into the following three themes: Barriers associated with mother and infant, Barriers associated with health professionals, and Organizational barriers. Conclusions In Japan, most hospitals that responded provided general breastfeeding support from the antenatal to postpartum periods. However, the benefits of breastfeeding in terms of preventing the incidence of type 2 diabetes following GDM were insufficiently communicated to women with GDM. Furthermore, there were numerous barriers to promoting breastfeeding among women with GDM.


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