EVALUATION PATIENT'S QUALITY OF LIFE WHO HAVE PAINFUL AND PARESTETIC SYMPTOMS OF ORAL MUCOSA

2018 ◽  
Vol 20 (9) ◽  
pp. 57-61 ◽  
Author(s):  
E.G. Borisova ◽  
◽  
A.A. Komova ◽  
E.A. Nikitina ◽  
M.K. Pendyurina ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Mucosa

Oral mucosal manifestations of systemic disease

2021 ◽  
pp. 175573802110451
Author(s):  
Rebecca Iles ◽  
Melanie Simms ◽  
Alistair Ledsam
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Oral Mucosa ◽  
Systemic Disease ◽  
Health Related Quality ◽  
Diagnosis And Management ◽  
Wide Range ◽  
Related Quality ◽  
Health Related

Disorders spanning a wide range of body systems may, directly or indirectly, impact upon the orofacial tissues. Specifically, the oral mucosa may be the first, or most severely affected site of systemic disease, posing significant implications for oral health-related quality of life. It is not uncommon for patients to present to their GP with orofacial symptoms, therefore a firm understanding of how systemic disease can manifest in this way is important. This article will discuss oral mucosal presentations of systemic disease, aiming to improve understanding and recognition of these conditions, allowing appropriate referral for investigation, diagnosis and management.

scholarly journals P028 The anti-inflammatory effects of a poly-probiotic on the oral mucosa

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S145-S146
Author(s):  
E Marlina ◽  
B Hirani ◽  
V Mercadante ◽  
M Shephard ◽  
S Kishida ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Wound Healing ◽  
Oral Mucosa ◽  
Inflammatory Cytokine ◽  
Cytokine Production ◽  
Healthy Controls ◽  
E Coli ◽  
Live Bacteria ◽  
Anti Inflammatory

Abstract Background Probiotics have previously showed evidence of being efficacious in inducing and maintaining remission in post-operative recurrent pouchitis. The potential mechanism of action of probiotics has been attributed to their ability to reduce pro-inflammatory cytokine production, both within the mucosal tissue and systemically. We present our study which characterises the anti-inflammatory effects of probiotics on the oral epithelium and in the treatment of oral lichen planus (OLP), a chronic inflammatory disease of the oral mucosa. Methods VSL#3 (VSL#3-ACTIVE batch 703093 Exp date 04/2019) is a highly concentrated (450 billion live bacteria per sachet) poly-probiotic food supplement that contains eight different strains of live bacteria. The mouth ordinary epithelium cell line (MOE-1a) was stimulated with VSL#3 plus or minus the pro-inflammatory bacteria E. coli. The resultant effects on cytokine production and wound healing were measured using ELISA and live cell imaging. Wound closure was calculated using ImageJ software. OLP patients (n = 80) and healthy controls (n = 44) were recruited from UCLH Eastman Dental Hospital (Ethics 17/LO/0475) and saliva and blood samples tested for CXCL10 levels using an ELISA. OLP patients with active disease (n = 30) were recruited into a double-blind placebo-controlled proof-of-concept trial investigating the potential benefit of VSL#3 in the treatment of clinical symptoms (NCT03052179). Patients consumed two sachets twice daily for 30 days with a 30-day follow-up. Clinical questionnaires, saliva and peripheral blood were collected on days 0, 30 and 60. A daily quality of life and compliance diary was used by all participants. Results The addition of VSL#3 to MOE1a cells stimulated with E. coli resulted in a significant reduction in pro-inflammatory cytokine secretion and an acceleration in wound healing. OLP patients were found to have an elevation in the pro-inflammatory chemokine CXCL10 both locally (saliva) and systemically (serum) compared with healthy controls. Finally, the clinical trial demonstrated that VSL#3 was tolerated and safe for patients with OLP. Although there is no statistical evidence, descriptive results suggest that VSL#3 can confer some beneficial effects on patients with active OLP. We noted a reduction in the number of sites of disease activity and an improvement in quality of life in the VSL#3 group compared with placebo. Corticosteroid usage was also reduced in the VSL#3 group. Conclusion VSL#3 has the ability to improve oral epithelial wound healing and reduce pro-inflammatory cytokines secretion in vitro. In OLP, the consumption of VSL#3 seems to provide some clinical benefits, but due to the study size a more substantial multi-centre trial is necessary to confirm these observations.

Measuring the impact of oral mucosa disease on quality of life

2009 ◽  
Vol 19 (6) ◽  
pp. 603-606 ◽  
Author(s):  
Pía López-Jornet ◽  
Fabio Camacho-Alonso ◽  
Mayra Lucero Berdugo
Keyword(s):  
Quality Of Life ◽  
Oral Mucosa ◽  
The Impact

scholarly journals Impact of oral mucosa lesions on the quality of life related to oral health. An etiopathogenic study

2016 ◽  
pp. e178-e184 ◽  
Author(s):  
MC Villanueva-Vilchis ◽  
P Lopez-Rios ◽  
I Garcia ◽  
LA Gaitan-Cepeda
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Oral Mucosa

Optimisation of diagnostics and complex treatment of multi-form exudative erythema of cavity mucosa

2020 ◽  
pp. 4-8
Author(s):  
A.I. Bulgakova ◽  
Z.R. Hismatullina ◽  
M.V. Zatcepina
Keyword(s):  
Quality Of Life ◽  
Oral Mucosa ◽  
Erythema Multiforme ◽  
Comparison Group ◽  
Comparative Characteristic ◽  
Complex Treatment ◽  
Therapy Effectiveness ◽  
Group A ◽  
State And Local

The article presents the results of studies of complex treatment oral mucosa of patients with Erythema multiforme in detail of the developed algorithm. Subjective and objective criteria of oral mucosa state and local humoral immunity are proposed for evaluation of therapy effectiveness in patients with multi-form exudative erythema in the main and comparison group. A comparative characteristic of dental indicators of quality of life was made according to the questionnaire OHIP-14-RU in both groups.

scholarly journals Impact on Quality of Life of Oral Diseases Related to Stress

2020 ◽  
pp. 239-249
Author(s):  
Diana I. Rivera-Reza DDS ◽  
María C. Villanueva-Vilchis DDS, MSc, PhD ◽  
Luis A. Gaitán-Cepeda DDS, MSc, PhD
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Oral Mucosa ◽  
Negative Impact ◽  
Health Impact ◽  
Poor Quality ◽  
Oral Diseases ◽  
And Gender ◽  
The One

It has been suggested that oral mucosa diseases related to stress have a negative impact on the quality of life. However, the information regarding which aspects are the most affected is inconclusive. The objective was to compare the quality of life associated with oral health in two groups: Cases formed by 21 patients coming from a teaching clinic, suffering oral lichen planus, recurrent aphthous stomatitis, and burning mouth syndrome; Control formed by 42 healthy subjects matched for age and gender. Oral Health Impact Profile questionnaire was applied. Statistical analysis showed that group Cases has worse quality of life (p 0.03) than the one of controls, specifically on psychological discomfort (p 0.027), physical disability (p 0.004); and handicap dimensions (p 0.002; RM 5.63 IC1.58-20.80). It was concluded that patients suffering oral mucosa disease related to stress showed poor quality of life.

scholarly journals EFFICIENCY OF THE INTEGRATED METHOD OF TREATMENT OF CHRONIC MECHANICAL TRAUMA OF THE MUTUAL SHELL OF THE MUTUAL PATIENTS IN PATIENTS WITH SUGAR DIABETES OF 1 TYPE

2018 ◽  
Vol 14 (2) ◽  
pp. 12-18
Author(s):  
Инна Жаркова ◽  
Inna Zharkova ◽  
Миляуша Кабирова ◽  
Milyausha Kabirova ◽  
Лариса Герасимова ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Oral Mucosa ◽  
Mechanical Trauma ◽  
Local Immunity ◽  
Chronic Injuries

Background Diabetes mellitus is a chronic disease that affects several hundred million people. In the presence of type 1 diabetes mellitus, there is a xerostomia, a violation of microcirculation, epithelial regeneration, a change in local immunity, the accumulation of glycated hemoglobin, which disrupts the supply of nutrients, and reduces the resistance of tissues to the action of foreign microorganisms, leading to the formation of a hard-to-treat chronic mechanical injury of the oral mucosa. Objectives Conduct an analysis of the efficacy of the complex treatment for chronic mechanical trauma of the oral mucosa in patients with type 1 diabetes based on clinical, dental, immunological, sociological research methods and functional vascular studies. Methods The dental, clinical status, overall quality of life, local immunological status and hemodynamics of the oral mucosa before and after treatment of chronic injuries of the oral mucosa in patients with type 1 diabetes mellitus by the traditional method compared with the scheme developed by us. Results As a result of the study, the success of treatment of chronic injuries of the oral mucosa in patients with type 1 diabetes according to our method is more effective than traditional treatment: by 20 % in terms of dental status, clinical symptoms and cytokine profile; complete disappearance of inflammatory changes in the oral mucosa 50 % improved the quality of life; the condition of the microcirculatory channel of the oral mucosa reached the figures of the control group. Conclusions With the application of the method of treatment of chronic mechanical trauma proposed by us in patients with type 1 diabetes mellitus using the Optotan physiotherapeutic laser apparatus with 5 % of mexidol and Ozonid oil, the therapy proved highly effective, based on the results of the study.

scholarly journals How to Manage Xerostomia in Prosthodontics???

2013 ◽  
Vol 01 (03) ◽  
pp. 144-151 ◽  
Author(s):  
Opinder Singh ◽  
Neeraj Mittal ◽  
Rishi Saini ◽  
◽  
Keyword(s):  
Quality Of Life ◽  
Oral Mucosa ◽  
The Elderly ◽  
The Body ◽  
Treatment Modalities ◽  
Improve Quality ◽  
Removable Prosthesis

AbstractSaliva is known as the mirror of the body. It is not only essential for retention of removable prosthesis but also protects the oral mucosa from injury by its lubricating effect. Xerostomia or hyposalivation is a commonly encountered condition especially among the elderly that needs to be treated to improve quality of life in denture wearers. This article reviews the various etiologic factors and treatment modalities in patients with xerostomia.

scholarly journals Oral rehabilitation of microstomia

2021 ◽  
Vol 6 (2) ◽  
pp. 136-141
Author(s):  
L. N. Smerdina ◽  
E. A. Tyo ◽  
Yu. G. Smerdina
Keyword(s):  
Quality Of Life ◽  
Oral Mucosa ◽  
Clinical Case ◽  
Mouth Opening ◽  
Facial Aesthetics ◽  
Oral Rehabilitation ◽  
Upper Jaw

Here we present a clinical case of microstomia with the focus on the oral rehabilitation of the patient. Microstomia, an abnormal contracture of the mouth, occurred in this case as a result of alveolar resection due to cancer, and scarring impeded mouth opening. The patient needed a partial removable laminar denture for the upper jaw. Prosthetics became possible upon normalization of oral mucosa. We describe the imprint preparation features in conditions of lacking right alveolar appendix and crossover fold after surgery. The formation of the wax board in combination with molding allowed demarcation of denture border. The laminar denture successfully replaced jaw and teeth defects, restored proper mastication, improved mouth moistening and speech, as well as facial aesthetics and quality of life. 

scholarly journals The incidence of oral dryness in people over 65 years living in Lublin

2015 ◽  
Vol 28 (4) ◽  
pp. 250-253
Author(s):  
Katarzyna Kamińska-Pikiewicz ◽  
Teresa Bachanek ◽  
Renata Chałas
Keyword(s):  
Quality Of Life ◽  
Nursing Homes ◽  
Elderly People ◽  
Oral Mucosa ◽  
Drug Administration ◽  
Questionnaire Survey ◽  
Side Effect ◽  
Saliva Secretion ◽  
Oral Dryness

Abstract Saliva plays an important part in naturally maintaining oral homeostasis. Dry mouth or 'xerostomia', is a serious problem connected with decreased saliva secretion which considerably limits the quality of life in elderly people. The aim of the study was the assessment of the subjective oral dryness in the oral mucosa in people over 65 living in Lublin, Poland. The study was conducted among 240 people aged 65 to 96. The patients were placed into two groups: I - 117 residents of nursing homes, II - 123 people living with their families. Assessment of the subjective oral dryness taking into account the place of residence, sex and drug administration was performed based on a questionnaire survey. In the group of nursing homes residents, 32.48% of the surveyed experienced subjective oral dryness, while among the seniors living with their families, 33.33% reported this kind of discomfort. The conducted analysis revealed that oral dryness was more common amongst women than men, and it can be very often a side-effect of administered medicine drugs.

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