scholarly journals First two autochthonous dengue virus infections in metropolitan France, September 2010

2010 ◽  
Vol 15 (39) ◽  
Author(s):  
G La Ruche ◽  
Y Souarès ◽  
A Armengaud ◽  
F Peloux-Petiot ◽  
P Delaunay ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Vector Control ◽  
Dengue Fever ◽  
Aedes Albopictus ◽  
Case Finding ◽  
Control Measures ◽  
Active Case Finding ◽  
Virus Infections ◽  
First Time ◽  
Local Transmission

In September 2010, two cases of autochthonous dengue fever were diagnosed in metropolitan France for the first time. The cases occurring in Nice, south-east France, where Aedes albopictus is established, are evidence of dengue virus circulation in this area. This local transmission of dengue calls for further enhanced surveillance, active case finding and vector control measures to reduce the spread of the virus and the risk of an epidemic.

Environmental Vector Control Practices among Households of Patients with Dengue Fever during the Epidemic of 2018 in Kerala, India

2021 ◽  
Vol 8 (02) ◽  
pp. 48-52
Author(s):  
Chintha Sujatha ◽  
Reshma Rajan Sudha ◽  
Sreejith Lalitha Krishnankutty ◽  
Prajitha Kannamkottapilly Chandrasekharan
Keyword(s):  
Vector Control ◽  
Dengue Fever ◽  
Protective Factor ◽  
Significant Risk ◽  
Public Health Problem ◽  
Community Level ◽  
Control Measures ◽  
Major Public Health Problem ◽  
Cross Sectional ◽  
Breeding Habitats

BACKGROUND Dengue fever is a major public health problem in Kerala. Vector control measures practiced at household level is the most cost-effective way of controlling dengue. This study aims to assess environmental measures of vector control practised among households of suspected or confirmed dengue patients in Thiruvananthapuram district of Kerala. METHODS A cross sectional study was done among households of patients diagnosed with dengue fever and reported in Integrated Disease Surveillance Programme (IDSP) in Thiruvananthapuram district from June to December 2018. Investigators interviewed the household members and made direct observations to collect data on vector control practices using a structured questionnaire. RESULTS A total of 108 houses were surveyed. Potential breeding habitats were found in 58 (53.7 %) houses. Aedes larva was found in containers from four (3.7 %) houses. Dry day observance was not regular with only 5 (4.6 %) houses practicing it weekly. Waste management practiced was proper in 47 (43.5 %) houses. Community level pre monsoon preparedness for epidemics was done in the vicinity of 53 (49.1 %) houses and it was found to be a protective factor against presence of breeding habitats in and around houses (p = 0.013). Low education (p = 0.012) and low occupational status (p = 0.017) were found to be significant risk factors. CONCLUSIONS Even during an epidemic, with occurrence of infections in the family, only half of the households are practising adequate vector control methods. Community level interventions and targeted information education campaign will help improve practice of environmental methods of vector control in dengue. KEYWORDS Dengue, Vector Control, Aedes Control, Environmental Methods, Community Interventions

scholarly journals Dengue virus: A review

2022 ◽  
Vol 8 (4) ◽  
pp. 243-247
Author(s):  
Narinder Singh ◽  
Ajeet Pal Singh ◽  
Amar Pal Singh
Keyword(s):  
Public Health ◽  
Dengue Virus ◽  
Dengue Fever ◽  
Rna Virus ◽  
Hemorrhagic Fever ◽  
Health Concern ◽  
Virus Infections ◽  
Public Health Concern ◽  
Viral Illness ◽  
Life Threatening

Dengue fever is a mosquito-borne viral illness that is quickly spreading over the globe, with significant death and morbidity rates. Dengue fever is an acute viral infection transmitted by Aedes mosquitos and caused by an RNA virus from the Flaviviridae family. The symptoms might vary from asymptomatic fever to life-threatening complications including hemorrhagic fever and shock. Although dengue virus infections are normally self-limiting, the disease has become a public health concern in tropical and subtropical countries. Dengue fever is a major public health concern owing to its rapid worldwide spread, and its burdens are now unmet due to a lack of accurate therapy and a simple diagnostic approach for the early stages of illness.

scholarly journals PERAN GEN STRUKTURAL, GEN NON-STRUKTURAL, DAN UNTRANSLATED REGION DALAM PERAKITAN VIRUS DENGUE

2015 ◽  
Vol 7 (2) ◽  
Author(s):  
Meiranty C. Pangerapan ◽  
Beivy J. Kolondam
Keyword(s):  
Aedes Aegypti ◽  
Dengue Virus ◽  
Dengue Fever ◽  
Aedes Albopictus ◽  
Untranslated Region ◽  
Rna Virus ◽  
Virus Genome ◽  
Interferon Response ◽  
Endoplasmic Reticulum Membrane ◽  
Structural Genes

Abstract: Dengue virus is a single-stranded RNA virus that belongs to Flaviviridae family. This virus causes dengue fever which is transmitted by Aedes aegypti dan Aedes albopictus. There are four serotypes of dengue virus; all of them can cause dengue fever. Understanding the genomics of dengue virus is important for research and diagnostics. The genome of dengue virus is 11 kilo-base long. It consists of 5’-untranslated region (5’-UTR), three structural genes (coding capsid protein, pre-membrane/membrane, and envelope), seven non-structural genes (coding NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5 proteins) and 3’-UTR. Non-structural genes are encoding proteins of viral RNA replication, interferon response, viral assembly and secretion, endoplasmic reticulum membrane invagination induction, immune-mediator induction, and RNA 5’-caping.Keywords: dengue virus, genome, structural genes, non-structural genes, untranslated region.Abstrak: Virus dengue merupakan virus RNA beruntai tunggal yang termasuk dalam famili Flaviviridae. Virus ini adalah penyebab penyakit demam berdarah dengue yang ditransmisikan melalui nyamuk Aedes aegypti dan Aedes albopictus. Ada empat serotipe virus dengue yang telah dikenal secara luas yang ada semuanya dapat menimbulkan penyakit demam berdarah. Pemahaman tentang genomik virus dengue sangat penting untuk pengembangan penelitian dan juga untuk keperluan diagnostik. Genom virus dengue memiliki panjang 11 kilo basa. Genomnya tersusun atas 5’-untranslated region (5’-UTR), tiga gen struktural (mengodekan protein kapsid, premembran/membran dan amplop), tujuh gen non-struktural (mengodekan protein NS1, NS2A, NS2B, NS3, NS4A, NS4B dan NS5) dan 3’-UTR. Gen-gen non-struktural mengodekan protein untuk replikasi RNA virus, respon interferon, perakitan, sekresi partikel virus, menginduksi invaginasi membran retikulum endoplasma, induksi imunomediator dan penambahan tudung pada ujung 5’ RNA.Kata kunci: virus dengue, genom, gen struktural, gen non-struktural, untranslated region

scholarly journals A comparative study of dengue virus vectors in major parks and adjacent residential areas in Ho Chi Minh City, Vietnam

2022 ◽  
Vol 16 (1) ◽  
pp. e0010119
Author(s):  
Trang Thi Thuy Huynh ◽  
Noboru Minakawa
Keyword(s):  
Dengue Virus ◽  
Vector Control ◽  
Aedes Albopictus ◽  
Urban Parks ◽  
Prevalence Ratio ◽  
Ho Chi Minh City ◽  
Adult Density ◽  
Residential Areas ◽  
Larval Habitats ◽  
Virus Vectors

The primary dengue virus vectors, Aedes aegypti and Aedes albopictus, are primarily daytime biting mosquitoes. The risk of infection is suspected to be considerable in urban parks due to visitor traffic. Despite the importance of vector control for reducing dengue transmission, little information is available on vector populations in urban parks. The present study characterized mosquito habitats and estimated vector densities in the major urban parks in Ho Chi Minh City, Vietnam and compared them with those in adjacent residential areas. The prevalences of habitats where Aedes larvae were found were 43% and 9% for the parks and residential areas, respectively. The difference was statistically significant (prevalence ratio [PR]: 5.00, 95% CI: 3.85–6.49). The prevalences of positive larval habitats were significantly greater in the parks for both species than the residential areas (PR: 1.52, 95% CI: 1.04–2.22 for A. aegypti, PR: 10.10, 95% CI: 7.23–14.12 for A. albopictus). Larvae of both species were positively associated with discarded containers and planters. Aedes albopictus larvae were negatively associated with indoor habitats, but positively associated with vegetation shade. The adult density of A. aegypti was significantly less in the parks compared with the residential areas (rate ratio [RR]; 0.09, 95% CI: 0.05–0.16), while the density of A. albopictus was significantly higher in the parks (RR: 9.99, 95% CI: 6.85–14.59). When the species were combined, the density was significantly higher in the parks (RR: 2.50, 95% CI: 1.92–3.25). The urban parks provide suitable environment for Aedes mosquitoes, and A. albopictus in particular. Virus vectors are abundant in the urban parks, and the current vector control programs need to have greater consideration of urban parks.

scholarly journals Listeriosis outbreak likely due to contaminated liver pâté consumed in a tavern, Austria, December 2018

2019 ◽  
Vol 24 (39) ◽  
Author(s):  
Adriana Cabal ◽  
Franz Allerberger ◽  
Steliana Huhulescu ◽  
Christian Kornschober ◽  
Burkhard Springer ◽  
...  
Keyword(s):  
Gastrointestinal Symptoms ◽  
Meat Products ◽  
Case Finding ◽  
Sequence Type ◽  
Control Measures ◽  
Whole Genome Sequence ◽  
Active Case Finding ◽  
Local Production ◽  
Outbreak Strain ◽  
Age Range

In late December 2018, an outbreak of listeriosis occurred after a group of 32 individuals celebrated in a tavern in Styria, Austria; traditional Austrian food (e.g. meat, meat products and cheese) was served. After the celebration, 11 individuals developed gastrointestinal symptoms, including one case with severe sepsis. Cases had consumed mixed platters with several meat products and pâtés originating from a local production facility (company X). Human, food and environmental samples taken from the tavern and company X were tested for L. monocytogenes. Whole genome sequence-based typing detected a novel L. monocytogenes strain of serotype IVb, sequence type 4 and CT7652 in 15 samples; 12 human, two food and one environmental sample from company X with an allelic difference of 0 to 1. Active case finding identified two further cases who had not visited the tavern but tested positive for the outbreak strain. In total, 13 cases (seven females and six males; age range: 4–84 years) were identified. Liver pâté produced by company X was identified as the likely source of the outbreak. Control measures were implemented and since the end of December 2018, no more cases were detected.

scholarly journals Pandemic-associated mobility restrictions could cause increases in dengue virus transmission

2021 ◽  
Vol 15 (8) ◽  
pp. e0009603
Author(s):  
Sean M. Cavany ◽  
Guido España ◽  
Gonzalo M. Vazquez-Prokopec ◽  
Thomas W. Scott ◽  
T Alex Perkins
Keyword(s):  
Dengue Virus ◽  
Vector Control ◽  
Human Mobility ◽  
Control Measures ◽  
Optimal Time ◽  
Multiple Infections ◽  
Dengue Vector ◽  
Mosquito Abundance ◽  
Dengue Vector Control ◽  
At Home

Background The COVID-19 pandemic has induced unprecedented reductions in human mobility and social contacts throughout the world. Because dengue virus (DENV) transmission is strongly driven by human mobility, behavioral changes associated with the pandemic have been hypothesized to impact dengue incidence. By discouraging human contact, COVID-19 control measures have also disrupted dengue vector control interventions, the most effective of which require entry into homes. We sought to investigate how and why dengue incidence could differ under a lockdown scenario with a proportion of the population sheltered at home. Methodology & principal findings We used an agent-based model with a realistic treatment of human mobility and vector control. We found that a lockdown in which 70% of the population sheltered at home and which occurred in a season when a new serotype invaded could lead to a small average increase in cumulative DENV infections of up to 10%, depending on the time of year lockdown occurred. Lockdown had a more pronounced effect on the spatial distribution of DENV infections, with higher incidence under lockdown in regions with higher mosquito abundance. Transmission was also more focused in homes following lockdown. The proportion of people infected in their own home rose from 54% under normal conditions to 66% under lockdown, and the household secondary attack rate rose from 0.109 to 0.128, a 17% increase. When we considered that lockdown measures could disrupt regular, city-wide vector control campaigns, the increase in incidence was more pronounced than with lockdown alone, especially if lockdown occurred at the optimal time for vector control. Conclusions & significance Our results indicate that an unintended outcome of lockdown measures may be to adversely alter the epidemiology of dengue. This observation has important implications for an improved understanding of dengue epidemiology and effective application of dengue vector control. When coordinating public health responses during a syndemic, it is important to monitor multiple infections and understand that an intervention against one disease may exacerbate another.

scholarly journals Larvicidal activity of phytoextracts against dengue fever vector, Aedes aegypti - A review

2018 ◽  
Vol 5 (4) ◽  
pp. 167-174 ◽  
Author(s):  
Kalarikkal Venugopalan Lakshmi ◽  
Ambalaparambil Vasu Sudhikumar ◽  
Embalil Mathachan Aneesh
Keyword(s):  
Life Cycle ◽  
Aedes Aegypti ◽  
Vector Control ◽  
Dengue Fever ◽  
Inhibitory Action ◽  
Control Measures ◽  
Mosquito Vectors ◽  
Chemical Insecticide ◽  
Insecticide Application ◽  
Efficient Control

Since Aedes aegypti is considered as the major vector of dengue fever, development of strategies to accomplish improved vector control without much interference in the environment composition are more common. As phytochemicals are now in the run for achieving this goal, this review is a humble attempt to recognize the plant species and their larvicidal efficacy with their inhibitory action on the life cycle of the species of interest, that has been documented through various studies conducted till date. Here we also discuss the synergistic impact of a number of phytoextracts which will provide more efficient control measures for mosquito vectors. All these studies are an exploration for a risk-free vector control tactic to replace the current chemical insecticide application for the betterment of our nature.

Risk of Dengue Spread from the Philippines through International Air Travel

2015 ◽  
Vol 2501 (1) ◽  
pp. 25-30 ◽  
Author(s):  
Lauren M. Gardner ◽  
Sahotra Sarkar
Keyword(s):  
Aedes Aegypti ◽  
Dengue Fever ◽  
Aedes Albopictus ◽  
Structural Damage ◽  
The Philippines ◽  
Control Measures ◽  
Monitoring And Control ◽  
Distribution Models ◽  
Breeding Grounds ◽  
Traffic Volumes

Epidemics of dengue fever occur every 3 to 4 years in the Philippines. The risk of a dengue fever outbreak in the Philippines has been heightened since Typhoon Haiyan struck the region in November 2013 because recovery efforts have been slow to progress. The structural damage caused by the typhoon resulted in an abundance of standing water, which can serve as mosquito breeding grounds. Should an outbreak of dengue occur, infected travelers departing the Philippines pose a risk because they may introduce the dengue virus into local vector populations (of Aedes aegypti and Aedes albopictus) at their destinations. This study quantifies the risk posed by potentially infected travelers departing the Philippines by using a network model that incorporates predictive species distribution models, demographic features of destination areas, and air traffic volumes. The analysis reveals that a majority of travelers departing Philippine airports deplane in regions suitable for harboring Aedes aegypti or Aedes albopictus; this factor increases the likelihood of further spread of the disease if an outbreak were to occur. Because it is impractical to implement all possible monitoring and control measures at all locations connected to the Philippines, this analysis ranks the set of candidates and thus allows surveillance resources to be optimally deployed.

scholarly journals Fatal and mild primary dengue virus infections imported to Norway from Africa and south-east Asia, 2008-2010

2010 ◽  
Vol 15 (38) ◽  
Author(s):  
K Vainio ◽  
S Noraas ◽  
M Holmberg ◽  
H Fremstad ◽  
M Wahlstrøm ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Dengue Fever ◽  
Fatal Case ◽  
Fatal Outcome ◽  
Dengue Shock Syndrome ◽  
Virus Infections ◽  
Virus Serotype ◽  
Serotype 1 ◽  
Type 3

Between 2008 and 2010, eight cases of viraemic dengue fever in travellers were diagnosed in Norway. They had returned from Eritrea, Thailand and Indonesia. All cases were primary dengue infections, seven non-complicated dengue fever and one dengue shock syndrome with a fatal outcome. Four patients were infected with dengue virus serotype 1, one with type 2 and three with type 3. Two cases from Thailand, the fatal case and the two imported from Eritrea were infected with type 1.

scholarly journals Adapting active case-finding for TB during the COVID-19 pandemic in Yogyakarta, Indonesia

2021 ◽  
Vol 11 (2) ◽  
pp. 41-49
Author(s):  
G. Chan ◽  
R. Triasih ◽  
B. Nababan ◽  
P. du Cros ◽  
N. Wilks ◽  
...  
Keyword(s):  
Health Services ◽  
Negative Impact ◽  
Case Finding ◽  
Control Measures ◽  
Case Detection ◽  
Active Case Finding ◽  
Active Case ◽  
Target Populations ◽  
Infection Control Measures ◽  
Potential Strategy

The COVID-19 pandemic and response measures, including lockdowns and the reorientation of health services, have disrupted essential health services for other diseases, including TB, HIV and malaria. For TB, reductions in case detection due to the COVID-19 pandemic are projected to result in increased TB transmission, morbidity and mortality. Active case-finding (ACF) for TB using community-based approaches is a potential strategy to offset reductions in TB detection by obviating the need for patients to seek care at a health facility. A number of approaches can be used to conduct TB ACF safely and screen designated target populations while managing the risks of SARS-CoV-2 transmission for staff, individuals and the community. We present a framework of options for and experience of adapting TB ACF services in response to the challenges of COVID-19 in our programme in Yogyakarta, Indonesia. Key changes have included revised prioritisation of target populations focusing on household contacts, reducing case-finding throughput, implementation of additional infection control measures and precautions, and integration of COVID-19 screening among those being screened for TB. Our approach could inform other programmes seeking to adapt TB ACF services to mitigate the negative impact of COVID-19 on TB case detection.

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