Scientific Opinion on the substantiation of health claims related to caffeine and increased fat oxidation leading to a reduction in body fat mass (ID 735, 1484), increased energy expenditure leading to a reduction in body weight (ID 1487), increased alert

Isoliquiritigenin (ILG) is a flavonoid constituent of Glycyrrhizae plants. The current study investigated the effects of ILG on diet-induced obesity and metabolic diseases. C57BL/6J mice were fed a normal diet (AIN-76 purified diet), high-fat diet (40 kcal% fat), and high-fat diet +0.02% (w/w) ILG for 16 weeks. Supplementation of ILG resulted in decreased body fat mass and plasma cholesterol level. ILG ameliorated hepatic steatosis by suppressing the expression of hepatic lipogenesis genes and hepatic triglyceride and fatty acid contents, while enhancing β-oxidation in the liver. ILG improved insulin resistance by lowering plasma glucose and insulin levels. This was also demonstrated by the intraperitoneal glucose tolerance test (IPGTT). Additionally, ILG upregulated the expression of insulin signaling-related genes in the liver and muscle. Interestingly, ILG elevated energy expenditure by increasing the expression of thermogenesis genes, which is linked to stimulated mitochondrial biogenesis and uncoupled cellular respiration in brown adipose tissue. ILG also suppressed proinflammatory cytokine levels in the plasma. These results suggest that ILG supplemented at 0.02% in the diet can ameliorate body fat mass, plasma cholesterol, non-alcoholic fatty liver disease, and insulin resistance; these effects were partly mediated by increasing energy expenditure in high-fat fed mice.

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Aerobic exercise-induced changes in body composition and blood lipids in young women

Medicina ◽

10.3390/medicina46020019 ◽

2010 ◽

Vol 46 (2) ◽

pp. 129 ◽

Cited By ~ 13

Author(s):

Arvydas Stasiulis ◽

Asta Mockienė ◽

Daiva Vizbaraitė ◽

Pranas Mockus

Keyword(s):

Body Mass Index ◽

Body Composition ◽

Body Weight ◽

Body Mass ◽

Body Fat ◽

Fat Mass ◽

Blood Lipids ◽

Density Lipoprotein ◽

Body Fat Mass ◽

Cycling Training

The objective of the study was to assess changes in body composition, blood lipid and lipoprotein concentrations in 18–24-year-old women during the period of two-month aerobic cycling training. Material and methods. Young, healthy, nonsmoking women (n=19) volunteered to participate in this study. They were divided in two groups: experimental (E, n=10) and control (C, n=9). The subjects of group E exercised 3 times a week with intensity of the first ventilatory threshold and duration of 60 min. The group C did not exercise regularly over a two-month period of the experiment. The subjects of group E were tested before and after 2, 4, 6 and 8 weeks of the experiment. The participants of group C were tested twice with an eight-week interval. Results. Body weight, body mass index, body fat mass, and triacylglycerol (TAG) concentration decreased and high-density lipoprotein cholesterol (HDL-ch) concentration increased after the 8-week training program in the experimental group (P<0.05). Blood total cholesterol (Tch) and low-density lipoprotein cholesterol (LDL-ch) concentrations did not change significantly. Body weight and body mass index started to decrease after 2 weeks of the experiment, but significant changes were observed only after 6 and 8 weeks. Body fat mass was significantly decreased after 2 and 8 weeks of aerobic training. A significant increase in HDL-ch concentration was observed after 4, 6, and 8 weeks. A significant decrease in TAG concentration was observed after 2-week training. No significant changes in all the parameters except TAG (it was slightly increased) were seen in the control group. Conclusions. The two-month aerobic cycling training (within VT1, 60-min duration, three times a week) may induce significant changes in the parameters of body composition – body weight, body mass index, body fat mass, and blood lipids – in young women. The following significant changes were observed: TAG level decreased after 2 weeks, body mass and body mass index decreased after 6 weeks, body fat mass decreased and HDL-ch level increased after 8 weeks. Peak oxygen uptake increased after 4 weeks.

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Effects of conjugated linoleic acid on body weight and body fat mass in overweight and obese Korean women

The FASEB Journal ◽

10.1096/fasebj.22.2_supplement.692 ◽

2008 ◽

Vol 22 (S2) ◽

pp. 692-692

Author(s):

Jung Hee Kim ◽

Ok Hyun Kim

Keyword(s):

Body Weight ◽

Linoleic Acid ◽

Conjugated Linoleic Acid ◽

Body Fat ◽

Fat Mass ◽

Body Fat Mass ◽

Korean Women

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Effects of omega-3 supplementation on body weight and body fat mass: A systematic review

Clinical Nutrition ESPEN ◽

10.1016/j.clnesp.2021.04.023 ◽

2021 ◽

Author(s):

Felipe Mendes Delpino ◽

Lílian Munhoz Figueiredo ◽

Bruna Gonçalves Cordeiro da Silva

Keyword(s):

Systematic Review ◽

Body Weight ◽

Body Fat ◽

Fat Mass ◽

Body Fat Mass ◽

Omega 3

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Laser Acupuncture Reduces Body Fat in Obese Female Undergraduate Students

International Journal of Photoenergy ◽

10.1155/2012/730351 ◽

2012 ◽

Vol 2012 ◽

pp. 1-4 ◽

Cited By ~ 3

Author(s):

Xiao-Guang Liu ◽

Juan Zhang ◽

Jian-Liang Lu ◽

Timon Cheng-Yi Liu

Keyword(s):

Body Weight ◽

Undergraduate Students ◽

Body Fat ◽

Fat Mass ◽

Body Weight Loss ◽

Laser Acupuncture ◽

Body Fat Mass ◽

Dependent Manner ◽

Waist Girth ◽

Before And After

The purpose of this study was to investigate the efficacies of laser acupunctures with different laser irradiation doses for body weight loss and body fat reduction in obese persons. Twentyeight subjects with simple obesity were divided into four groups receiving laser acupunctures at 0, 358, 478, and 597 J/cm2, respectively, which were applied to the acupoints of Cv 8, St 25, and Sp 15, six times per week for four weeks. Body weight (BW), body mass index (BMI), body fat mass (BFM), body fat percent, waist girth, hip girth, and waist-to-hip ratio (WHR) were measured before and after treatment. The laser groups receiving 358 and 597 J/cm2showed significant reductions in BW, BMI, BFM, waist girth, hip girth, and WHR after treatment compared with the placebo group. The percent reductions of BFM in the laser groups receiving 358 and 597 J/cm2were 4.29% and 3.94%, respectively, and the corresponding values of BW were 1.99% and 1.63%, respectively. In conclusion, laser acupuncture could reduce body fat mass and lower body weight in a dose-dependent manner in obese persons. Among the doses of 358, 478, and 597 J/cm2, both the 358 and 597 J/cm2doses were effective in the 4-week trial.

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Body measurements and serum lipid profile of overweight adult dogs fed diet with containing conjugated linoleic acid

Ciência Rural ◽

10.1590/s0103-84782011001100028 ◽

2011 ◽

Vol 41 (11) ◽

pp. 2020-2025 ◽

Cited By ~ 1

Author(s):

Nancy Lorena Montaño Rivera ◽

Ananda Portela Félix ◽

Fabiano Montiani Ferreira ◽

Ana Vitória Fisher da Silva ◽

Alex Maiorka

Keyword(s):

Body Weight ◽

Linoleic Acid ◽

Total Cholesterol ◽

Conjugated Linoleic Acid ◽

Body Fat ◽

Fat Mass ◽

Subcutaneous Tissue ◽

Body Fat Mass ◽

Tissue Thickness ◽

Significant Difference

Studies with human beings and animals have shown that dietary conjugated linoleic acid (CLA) promotes changes in body structure, markedly, body fat reduction. This research aimed to assess the effect of CLA (60% of conjugated linoleic acid methyl ester, at the proportion of 1:1 of the 9, 11: 10, 12 isomers) on changes in body weight, subcutaneous tissue thickness, body fat mass and concentration of serum lipids (triacylglycerols, total cholesterol, LDL and HDL) in overweight dogs. Dogs of different breeds weighting 16.85±7.13 assigned in a randomized assay. Two types of diets were offered for 120 days: control (-CLA) and test (+CLA, 0.3%). There was no difference between control and test groups considering body weight and serum levels of triacylglycerols, total cholesterol and LDL portion. There was a significant difference between the final and initial results for subcutaneous tissue thickness and body fat mass and for serum concentration of HDL in dogs supplemented with CLA. The addition of 0.3% of CLA in the diet of overweight dogs decreased the fat deposition on subcutaneous tissue and the development of body fat mass but increased blood levels of HDL.

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Seasonal variations of body mass, thermogenesis and digestive tract morphology in Apodemus chevrieri in Hengduan mountain region

Animal Biology ◽

10.1163/157075612x650140 ◽

2012 ◽

Vol 62 (4) ◽

pp. 463-478 ◽

Cited By ~ 14

Author(s):

Zhu Wan-long ◽

Yang Sheng-chang ◽

Zhang Lin ◽

Wang Zheng-kun

Keyword(s):

Body Weight ◽

Digestive Tract ◽

Energy Intake ◽

Body Mass ◽

Body Fat ◽

Fat Mass ◽

Seasonal Variations ◽

Body Fat Mass ◽

Serum Leptin ◽

Hengduan Mountain

Seasonal changes in an animal’s morphology, physiology, and behavior are considered to be an adaptive strategy for survival and reproductive success. We hypothesize that Apodemus chevrieri will change their thermogenesis seasonally and serum leptin will change with body mass or body fat mass. Seasonal variations in body mass (BM), basal metabolic rate (BMR), nonshivering thermogenesis (NST), digestive tract morphology, serum leptin and uncoupling protein 1 (UCP1) were measured in wild-trapped A. chevrieri in Hengduan mountain region. The results showed that the body weight of A. chevrieri was lowest in winter and highest in summer. Decreased BM in the winter was accompanied by increased energy intake and enhanced NST and UCP1 as well as by decreased body fat mass, adjusted digestive tract morphology and reduced levels of circulating leptin. Further, serum leptin were positively correlated with body weight and body fat mass, and negatively correlated with energy intake and UCP1 contents. These data suggest that wild A. chevrieri do not depend on a decrease in BM, but instead increase their thermogenic capacity to cope with cold stress. Leptin may be involved in the seasonal regulation in energy balance and thermogenesis in field A. chevrieri.

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