Abscess removal in a desert horned viper (Cerastes cerastes)

Venomous snakes are widely kept in captive as collections by private reptile keepers. A 7 years old male desert horned viper (Cerastes cerastes) was presented with a lump on the caudal part of the body. Proper physical restraining method using snake hook and transparent tubes was performed for clinical examination and radiography. Two radiography views revealed radiopaque in both lateral and dorsal recumbence. Differential diagnosis was tumor growth and abscess. Surgical intervention was indicated and performed with the viper induced with injectable anesthesia and maintained with gas anesthesia. Surgical correction with manually removing the abscess was performed. The NSAID, broad spectrum antibiotic, topical antibiotic and fluid therapy were performed post-surgery. Six weeks post-surgery the suture material was removed and wound was dry and healed well.

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Unusual Site for a White Nodule on the Palatine Tonsil: Presentation, Differential Diagnosis, and Discussion

Case Reports in Dentistry ◽

10.1155/2021/1371329 ◽

2021 ◽

Vol 2021 ◽

pp. 1-4

Author(s):

Ashwag Yagoub Aloyouny

Keyword(s):

Differential Diagnosis ◽

Clinical Presentation ◽

Surgical Intervention ◽

Fungal Infections ◽

The Body ◽

Palatine Tonsil ◽

Unusual Site ◽

Case Presentation ◽

Lymphoepithelial Cysts ◽

Malignant Lesions

Introduction. Palatine tonsils are part of the mucosa-associated lymphoid tissue, located in the oropharyngeal region. Although these tissues protect the body from foreign intruders, they are more prone to infections due to their anatomical structure and location. For instance, the differential diagnosis of a white lesion on the palatine tonsil can range from benign to malignant lesions. Oral lymphoepithelial cysts commonly arise as painless, yellowish nodules on the floor of the mouth and the ventral or lateral surface of the tongue. Case Presentation. This paper presents a rare case of an unusual site of a lymphoepithelial cyst (LEC) in the oral cavity. The lesion was located in the tonsil of a 20-year-old woman with a chief complaint of a painless, white lump in the back of the mouth for nine months. Discussion. The differential diagnosis of a white lesion on the palatine tonsil is caused by several factors, such as bacterial, viral, and fungal infections; trauma; stones; cysts; abscess; or cancer. In this case, both the clinical presentation and extra- and intraoral examinations were highly associated with LEC. Oral LEC etiopathogenesis is uncertain, and several theories have been proposed to discuss the causes of LEC. In addition, oral LEC could be monitored without surgical intervention if the nodule is asymptomatic. Conclusion. We emphasize the importance of a thorough clinical examination of oral and oropharyngeal lesions, which are usually neglected.

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Unilateral Laterothoracic Exanthem – Asymmetric Periflexural Exanthem of Childhood – a Case Report and Literature Review

Serbian Journal of Dermatology and Venerology ◽

10.1515/sjdv-2017-0007 ◽

2017 ◽

Vol 9 (2) ◽

pp. 49-52

Author(s):

Sonja Prćić ◽

Zorica Gajinov ◽

Anica Radulović ◽

Milan Matić ◽

Aleksandra Matić

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Literature Review ◽

Skin Eruption ◽

Clinical Diagnosis ◽

Broad Spectrum ◽

Maculopapular Rash ◽

The Body

Abstract Unilateral laterothoracic exanthem (ULE), or asymmetric periflexural exanthem of childhood (APEC), is an uncommon skin eruption that usually occurs in childhood, with unilateral distribution and self limiting course. The etiology of ULE is unknown, but viral cause is suspected. We report a case of ULE in a 4-year-old girl, that was associated with parvo virus B19 infection, and a brief selected literature review. The patient presented with unilateral maculopapular rash on the left side of the body which was asymptomatic and resolved spontaneously within 5 weeks. The clinical diagnosis of ULE may be precise, ruling out a broad spectrum of differential diagnosis, and prevent unnecessary examinations, whereas the patient is informed about the benign self-limiting nature of ULE.

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A 28-Year-Old Woman with Fever, Weight Loss, Pancytopenia, and Multiple Hepatosplenic and Bone Lesions

Case Reports in Infectious Diseases ◽

10.1155/2015/759856 ◽

2015 ◽

Vol 2015 ◽

pp. 1-4

Author(s):

Fereshte Sheybani ◽

Bezat Amiri ◽

HamidReza Naderi ◽

Mohammad Reza Sarvghad

Keyword(s):

Weight Loss ◽

Differential Diagnosis ◽

Broad Spectrum ◽

Clinical Manifestations ◽

Febrile Illness ◽

The Body ◽

Bone Lesions ◽

Zoonotic Infection ◽

Rare Presentation ◽

Multifocal Osteomyelitis

Brucellosis is a systemic zoonotic infection that can involve any organ or system in the body. It may present with a broad spectrum of clinical manifestations. Considering such myriad presentations, brucellosis should always be considered in the differential diagnosis of any febrile illness in a compatible epidemiological context. Here, we report a rare presentation of acute brucellosis with multifocal osteomyelitis and hepatosplenic lesions.

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Faculty Opinions recommendation of A broad-spectrum antibiotic adjuvant reverses multidrug-resistant Gram-negative pathogens.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.737972351.793575624 ◽

2020 ◽

Author(s):

Heath Murray ◽

Hannah Gaimster

Keyword(s):

Broad Spectrum ◽

Multidrug Resistant ◽

Broad Spectrum Antibiotic ◽

Gram Negative

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DIAGNOSTICS AND TREATMENT OF POISONING WITH THALLIUM

Токсикологический вестник ◽

10.36946/0869-7922-2018-5-9-15 ◽

2018 ◽

pp. 9-15 ◽

Cited By ~ 3

Author(s):

L. B. Zavaliy ◽

A. Yu. Simonova ◽

M. M. Potskhveriya ◽

Yu. N. Ostapenko ◽

M. G. Gadzhieva ◽

...

Keyword(s):

Differential Diagnosis ◽

Clinical Picture ◽

Clinical Guidelines ◽

The Body ◽

Biological Media ◽

Pathophysiological Mechanisms ◽

Thallium Poisoning ◽

The World

Cases of thallium poisonings are regularly reported in media. In the present work, the world experience in diagnostics and treatment of victims with thallium poisoning has been compiled and summarized, search for clinical guidelines for the diagnostics, treatment and rehabilitation of patients has been carried out. The toxicokinetics and toxicodynamics, as well as pathophysiological mechanisms of thallium influence on the body are described in detail. Toxic and lethal concentrations of poison in biological media, as well as its tropicity to various tissues and body systems were determined. The clinical picture depending on the timing of poisoning and the dose of poison is described in detail. Difficulties of the differential diagnosis are defined. The most interesting cases of criminal and household poisonings with various terms of establishment of the diagnosis, doses of poisoning and outcomes are presented.

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Trends in Antibiotic Prescribing in Out-of-Hours Primary Care in England from January 2016 to June 2020 to Understand Behaviours during the First Wave of COVID-19

Antibiotics ◽

10.3390/antibiotics10010032 ◽

2021 ◽

Vol 10 (1) ◽

pp. 32

Author(s):

Nina J. Zhu ◽

Monsey McLeod ◽

Cliodna A. M. McNulty ◽

Donna M. Lecky ◽

Alison H. Holmes ◽

...

Keyword(s):

Primary Care ◽

Time Series ◽

Patient Outcomes ◽

Broad Spectrum ◽

Antibiotic Prescribing ◽

Broad Spectrum Antibiotic ◽

Out Of Hours ◽

Broad Spectrum Antibiotics ◽

National Quality ◽

General Practices

We describe the trend of antibiotic prescribing in out-of-hours (OOH) general practices (GP) before and during England’s first wave of the COVID-19 pandemic. We analysed practice-level prescribing records between January 2016 to June 2020 to report the trends for the total prescribing volume, prescribing of broad-spectrum antibiotics and key agents included in the national Quality Premium. We performed a time-series analysis to detect measurable changes in the prescribing volume associated with COVID-19. Before COVID-19, the total prescribing volume and the percentage of broad-spectrum antibiotics continued to decrease in-hours (IH). The prescribing of broad-spectrum antibiotics was higher in OOH (OOH: 10.1%, IH: 8.7%), but a consistent decrease in the trimethoprim-to-nitrofurantoin ratio was observed OOH. The OOH antibiotic prescribing volume diverged from the historical trend in March 2020 and started to decrease by 5088 items per month. Broad-spectrum antibiotic prescribing started to increase in OOH and IH. In OOH, co-amoxiclav and doxycycline peaked in March to May in 2020, which was out of sync with seasonality peaks (Winter) in previous years. While this increase might be explained by the implementation of the national guideline to use co-amoxiclav and doxycycline to manage pneumonia in the community during COVID-19, further investigation is required to see whether the observed reduction in OOH antibiotic prescribing persists and how this reduction might influence antimicrobial resistance and patient outcomes.

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Broad-Spectrum Antibiotic Regimen Affects Survival in Patients Receiving Nivolumab for Non-Small Cell Lung Cancer

Pharmaceuticals ◽

10.3390/ph14050445 ◽

2021 ◽

Vol 14 (5) ◽

pp. 445

Author(s):

Min Jung Geum ◽

Chungsoo Kim ◽

Ji Eun Kang ◽

Jae Hee Choi ◽

Jae Song Kim ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Broad Spectrum ◽

Small Cell ◽

Defined Daily Dose ◽

Small Cell Lung ◽

Broad Spectrum Antibiotic ◽

Negatively Associated ◽

Daily Dose

Antibiotic-induced dysbiosis may affect the efficacy of immune checkpoint inhibitors. We investigated the impact of antibiotics on the clinical outcomes of nivolumab in patients with non-small cell lung cancer (NSCLC). Patients who received nivolumab for NSCLC between July 2015 and June 2018 and who were followed up until June 2020 were included in a retrospective cohort analysis. Of 140 eligible patients, 70 were on antibiotics. Overall survival (OS) was shorter in patients on antibiotics (ABX) compared to those not on antibiotics (NoABX) (p = 0.014). OS was negatively associated with piperacillin/tazobactam (PTZ) (HR = 3.31, 95% CI: 1.77–6.18), days of therapy (DOT) ≥ 2 weeks (HR = 2.56, 95% CI: 1.30–5.22) and DOT of PTZ. The defined daily dose (DDD) in PTZ (r = 0.27) and glycopeptides (r = 0.21) showed weak correlations with mortality. There was no difference in progression-free survival (PFS) between ABX and NoABX; however, PFS was negatively associated with the antibiotic class PTZ and DOT of PTZ. Therefore, the use of a broad-spectrum antibiotic, such as PTZ, the long-term use of antibiotics more than 2 weeks in total and the large amount of defined daily dose of specific antibiotics were associated with decreased survival in patients receiving nivolumab for NSCLC.

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First reported case of penile prosthesis infection from brucellosis: case report

African Journal of Urology ◽

10.1186/s12301-020-00090-1 ◽

2020 ◽

Vol 26 (1) ◽

Author(s):

Nabil Nabil Moohialdin ◽

Ahmad Shamsodini ◽

Steven K. Wilson ◽

Osama Abdeljaleel ◽

Ibrahim Alnadhari ◽

...

Keyword(s):

Case Report ◽

Broad Spectrum ◽

Surgical Intervention ◽

Penile Prosthesis ◽

Raw Milk ◽

Prosthesis Infection ◽

Case Presentation ◽

First Case ◽

Milk Ingestion

Abstract Background Infection after the penile prosthesis can be devastating to both the patient and surgeon with various complications and consequences. After introduction of antibiotic-coated implants, the rate of infection has dramatically decreased, but still we see uncommon organisms causing infection. We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. To our knowledge, this is the first reported case of brucellosis penile prosthesis infection. Case presentation We present a first case report of penile prosthesis infection by brucellosis due to raw milk ingestion. A 75-year-old, diabetic male patient presented with penile prosthesis infection 5 months post-penile exchange surgery due to mechanical malfunctioning of 2-piece penile prosthesis which was inserted 11 years ago. The initial treatment with broad spectrum antibiotics did not subside the infection. After diagnosis of brucellosis, the antibiotic was changed to anti-brucellosis (Rifampicin + Tetracycline). The patient improved dramatically and was discharged home with smooth follow-up course. Conclusion Brucellosis can cause infection of penile prosthesis and can be treated with anti-brucellosis antibiotics without necessitating surgical intervention and removal of prosthesis.

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