Structural changes of cardiac tissue in response to L-carnitine supplementation during endurance training in Wistar male rats toxicated by steroid anabolic hormone

2017 ◽  
Vol 21 (2) ◽  
pp. 86-95
Author(s):  
Fatemeh Habibpoor Karimabadi ◽  
Asieh Abbasi Daloii ◽  
Ahmad Abdi ◽  
seyed Javad Ziaolhagh ◽  
◽  
...  
Keyword(s):  
Endurance Training ◽  
Structural Changes ◽  
Cardiac Tissue ◽  
Male Rats ◽  
Carnitine Supplementation ◽  
Anabolic Hormone ◽  
Wistar Male Rats

Endurance training and LXR activation increased LXRα and ABCA1 transcripts in Wistar male rats

2018 ◽  
Vol 33 (3) ◽  
pp. 152-157 ◽  
Author(s):  
F. Kazeminasab ◽  
S.M. Marandi ◽  
K. Ghaedi ◽  
F. Esfarjani ◽  
J. Moshtaghian
Keyword(s):  
Endurance Training ◽  
Male Rats ◽  
Wistar Male Rats

The effect of endurance training on dynein motor protein expression in Wistar male rats sciatic nerves with diabetic neuropathy

2017 ◽  
Vol 21 (1) ◽  
pp. 10-19 ◽  
Author(s):  
Ali Khazani ◽  
Reza Gharakhanlou ◽  
Mohamad Reza Kordi ◽  
Mansoureh Movahedin ◽  
Shiva Jahani Golbar ◽  
...  
Keyword(s):  
Diabetic Neuropathy ◽  
Protein Expression ◽  
Endurance Training ◽  
Motor Protein ◽  
Male Rats ◽  
Dynein Motor ◽  
Sciatic Nerves ◽  
Wistar Male Rats

Endurance training enhances LXRα gene expression in Wistar male rats

2013 ◽  
Vol 113 (9) ◽  
pp. 2285-2290 ◽  
Author(s):  
Fatemeh Kazeminasab ◽  
Mohammad Marandi ◽  
Kamran Ghaedi ◽  
Fahimeh Esfarjani ◽  
Jamal Moshtaghian
Keyword(s):  
Gene Expression ◽  
Endurance Training ◽  
Male Rats ◽  
Wistar Male Rats

Fine Structural Changes in the Adenohypophyses of Rats Following Destruction of the Pituitary Stalk

1977 ◽  
Vol 35 ◽  
pp. 496-497
Author(s):  
K. Kovacs ◽  
E. Horvath ◽  
J. M. Bilbao ◽  
F. A. Laszlo ◽  
I. Domokos
Keyword(s):  
Structural Changes ◽  
Tissue Injury ◽  
Anterior Lobe ◽  
Uranyl Acetate ◽  
Male Rats ◽  
Pituitary Stalk ◽  
Sequence Of Events ◽  
Pituitary Glands ◽  
Electrolytic Lesions ◽  
Ultrathin Sections

Electrolytic lesions of the pituitary stalk in rats interrupt adenohypophysial blood flow and result in massive infarction of the anterior lobe. In order to obtain a deeper insight into the morphogenesis of tissue injury and to reveal the sequence of events, a fine structural investigation was undertaken on adenohypophyses of rats at various intervals following destruction of the pituitary stalk.The pituitary stalk was destroyed electrolytically, with a Horsley-Clarke apparatus on 27 male rats of the R-Amsterdam strain, weighing 180-200 g. Thirty minutes, 1,2,4,6 and 24 hours after surgery the animals were perfused with a glutaraldehyde-formalin solution. The skulls were then opened and the pituitary glands removed. The anterior lobes were fixed in glutaraldehyde-formalin solution, postfixed in osmium tetroxide and embedded in Durcupan. Ultrathin sections were stained with uranyl acetate and lead citrate and investigated with a Philips 300 electron microscope.

scholarly journals Endurance Training Regulates Expression of Some Angiogenesis-Related Genes in Cardiac Tissue of Experimentally Induced Diabetic Rats

Biomolecules ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 498
Author(s):  
Mojdeh Khajehlandi ◽  
Lotfali Bolboli ◽  
Marefat Siahkuhian ◽  
Mohammad Rami ◽  
Mohammadreza Tabandeh ◽  
...  
Keyword(s):  
Gene Expression ◽  
Endurance Training ◽  
Molecular Mechanisms ◽  
Cardiac Tissue ◽  
Critical Role ◽  
Diabetic Rats ◽  
Moderate Intensity ◽  
Pcr Analysis ◽  
Cardiac Tissues ◽  
The Impact

Exercise can ameliorate cardiovascular dysfunctions in the diabetes condition, but its precise molecular mechanisms have not been entirely understood. The aim of the present study was to determine the impact of endurance training on expression of angiogenesis-related genes in cardiac tissue of diabetic rats. Thirty adults male Wistar rats were randomly divided into three groups (N = 10) including diabetic training (DT), sedentary diabetes (SD), and sedentary healthy (SH), in which diabetes was induced by a single dose of streptozotocin (50 mg/kg). Endurance training (ET) with moderate-intensity was performed on a motorized treadmill for six weeks. Training duration and treadmill speed were increased during five weeks, but they were kept constant at the final week, and slope was zero at all stages. Real-time polymerase chain reaction (RT-PCR) analysis was used to measure the expression of myocyte enhancer factor-2C (MEF2C), histone deacetylase-4 (HDAC4) and Calmodulin-dependent protein kinase II (CaMKII) in cardiac tissues of the rats. Our results demonstrated that six weeks of ET increased gene expression of MEF2C significantly (p < 0.05), and caused a significant reduction in HDAC4 and CaMKII gene expression in the DT rats compared to the SD rats (p < 0.05). We concluded that moderate-intensity ET could play a critical role in ameliorating cardiovascular dysfunction in a diabetes condition by regulating the expression of some angiogenesis-related genes in cardiac tissues.

scholarly journals Pre-clinical investigations of Verbena officinalis L. tisane effects against induced stress in Wistar male rats

2020 ◽  
Author(s):  
Sonia Marlene Rodrigues Oliveira ◽  
Elsa Dias ◽  
Maria de Lourdes Pereira
Keyword(s):  
Male Rats ◽  
Induced Stress ◽  
Clinical Investigations ◽  
Wistar Male Rats

Increased Urinary Excretion of Carnitine and Acylcarnitine by Mercuric Chloride Is Reversed by 2,3-Dimercapto-1-Propanesulfonic Acid in Rats

2010 ◽  
Vol 29 (3) ◽  
pp. 313-317
Author(s):  
Waleed A. Al-Madani ◽  
Nikhat J. Siddiqi ◽  
Abdullah S. Alhomida ◽  
Haseeb A. Khan ◽  
Ibrahim A. Arif ◽  
...  
Keyword(s):  
Body Weight ◽  
Urinary Excretion ◽  
Mercuric Chloride ◽  
Free Carnitine ◽  
Male Rats ◽  
Significant Protection ◽  
Total Carnitine ◽  
Dose Dependent Increase ◽  
Dose Dependent ◽  
Wistar Male Rats

This investigation was aimed to study the effect of 2,3-dimercapto-1-propanesulfonic acid (DMPS) on mercuric chloride (HgCl2)-induced alterations in urinary excretion of various carnitine fractions including free carnitine (FC), acylcarnitine (AC), and total carnitine (TC). Different groups of Wistar male rats were treated with HgCl2 at the doses of 0.1, 0.5, 1.0, 2.0, and 3.0 mg/kg body weight, and the animals were sacrificed at 24 hours following HgCl2 injection. A separate batch of animals received HgCl2 (2 mg/kg) with or without DMPS (100 mg/kg) and sacrificed at 24 or 48 hours after dosing. Administration of HgCl2 resulted in statistically significant and dose-dependent increase in the urinary excretion of FC, AC, and TC in rats. However, the ratio of urinary AC:FC was significantly decreased by HgCl2. Pretreatment with DMPS offered statistically significant protection against HgCl2-induced alterations in various urinary carnitine fractions in rats.

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