scholarly journals The theory of free radicals and aging: A review article

2020 ◽  
Vol 4 (3) ◽  
pp. 8-14
Author(s):  
Pouya Farokhnezhad Afshar ◽  
Keyword(s):  
Free Radicals ◽  
Review Article

scholarly journals MOLECULAR BASES OF ATEROGENESIS

2019 ◽  
pp. 77-88
Author(s):  
P.A. Storozhenko ◽  
M.M. Rasulov ◽  
I.V. Zhigacheva ◽  
V.M. Gukasov ◽  
L.L. Myakinkova
Keyword(s):  
Risk Factors ◽  
Free Radicals ◽  
Mitochondrial Dysfunction ◽  
Oxygen Radicals ◽  
Vascular Dysfunction ◽  
Review Article ◽  
Molecular Bases

The review article provides evidence that mitochondrial dysfunction plays an important role in the initiation and development of atherosclerosis. Such aspects as the mechanism of mitochondrial oxidative dysfunction, the formation of reactive forms of oxygen radicals, the regulation of their formation and their «targets», the mechanisms of vascular dysfunction and atherosclerosis associated with mitochondrial dysfunction, the formation of free radicals and the role of mitochondrial dysfunction with various risk factors for atherosclerosis.

The role of protein-derived free radicals as intermediaries of oxidative processes

2014 ◽  
Vol 5 (2) ◽  
pp. 119-130 ◽  
Author(s):  
Camilo López-Alarcón ◽  
Andrea Arenas ◽  
Eduardo Lissi ◽  
Eduardo Silva
Keyword(s):  
Free Radicals ◽  
Reactive Species ◽  
Review Article ◽  
Main Target ◽  
Oxidative Processes ◽  
Protein Radicals

AbstractThe fact that proteins are the main target of reactive species formed in the cells and extracellular fluids has led to the realization of a great deal of research devoted to revealing the molecular and biological consequences associated with the presence of intermediary protein radicals. This review article describes and comments upon the main chemical pathways involving primary proteic radicals.

scholarly journals The Altered Water System: Excess Levels of Free Radicals Contribute to Carcinogenesis by Altering Arginine Vasopressin Production and Secretion and Promoting Dysregulated Water Homeostasis in Concert with Other Factors

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Amy Marie Beutler ◽  
Bradford N. Strand
Keyword(s):  
Free Radicals ◽  
Tumor Growth ◽  
Arginine Vasopressin ◽  
Large Body ◽  
Water System ◽  
Review Article ◽  
Radical Species ◽  
Water Homeostasis ◽  
Cycle Arrest ◽  
Pituitary Adrenal Axis

A large body of evidence accumulated during the last decade has revealed diverse roles of dysregulated water homeostasis in tumorigenesis. In particular, many tumors hypersecrete arginine vasopressin (AVP) causing hypoosmolar conditions associated with different cancers. Excess levels of free radicals and nonosmotic stimuli may act as signals in water homeostasis and induce the production and secretion of AVP. Hypoosmolar conditions cause alterations in the expression of many genes. Other alterations in hydration patterns may induce mutations and increase the levels of protein kinases to contribute to oncogenesis. Furthermore, AVP regulates the hypothalamic-pituitary-adrenal axis and angiogenesis, and its overproduction may contribute to tumor growth and metabolism. This review article describes a mechanism by which oxygen radical species and other free radicals act as signaling molecules that, in concert with increased AVP production and secretion, pleiotropically affect tumor growth and metabolism, resulting in dysregulated proliferation, cell cycle arrest, apoptosis, and genomic instability.

scholarly journals COMPOSTOS FENÓLICOS DO VINHO: ESTRUTURA E AÇÃO ANTIOXIDANTE

2004 ◽  
Vol 22 (2) ◽  
Author(s):  
MARIA EUGÊNIA DE OLIVEIRA MAMEDE ◽  
GLÁUCIA MARIA PASTORE
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Phenolic Compounds ◽  
Phenolic Acids ◽  
Chemical Structure ◽  
Red Wine ◽  
Biological Properties ◽  
Review Article ◽  
Antioxidant Action

Este trabalho de revisão teve por objetivo investigar as propriedades biológicas dos compostos fenólicos presentes em vinhos tinto e branco. Foram abordadas a composição, a atividade antioxidante e a estrutura química dos compostos fenólicos (flavonóides e ácidos fenólicos). Concluiu-se que a capacidade antioxidante dos compostos fenólicos está diretamente ligada à sua estrutura química, a qual pode estabilizar radicais livres. A ingestão diária e moderada de vinho pode promover a saúde e prevenir o risco de incidência de doenças do coração e certos tipos de câncer. No entanto, não deve ser considerada como tratamento para pessoas que já desenvolveram essas enfermidades. WINE PHENOLIC COMPOUNDS: STRUCTURE AND ANTIOXIDANT ACTION Abstract This review article had as objective to investigate the biological properties of the phenolic compounds present in white and red wine. The composition, antioxidant activity and chemical structure of the phenolic compounds (flavanoids and phenolic acids) were studied. It was concluded that the antioxadant capacity of the phenolic compounds is directed related to their chemical structure, which can stabilize free radicals. Daily and moderated ingestion of wine may promote health and prevent the risk of heart diesease incidence and certain types of cancer. However, it should not be considered as treatment for people who has already developed this diseases.

Desiderata in connection by the calibration of the MK-system

1966 ◽  
Vol 24 ◽  
pp. 348-349
Author(s):  
Th. Schmidt-Kaler
Keyword(s):  
Absolute Magnitude ◽  
Review Article ◽  
Stellar Systems ◽  
Astronomical Data ◽  
Intrinsic Colour

This is only an informal remark about some difficulties I am worrying about.I have tried to recalibrate the MK system in terms of intrinsic colour (B–V)0and absolute magnitudeMv. The procedures used have been described in a review article by Voigt (Mitt. Astr. Ges.1963, p. 25–35), and the results for stars of the luminosity classes Ia-O,I and II have been given also in Blaauw's article on the calibration of luminosity criteria in vol. III (Basic Astronomical Data, p. 401) ofStars and Stellar Systems.

Electron-deficient boron-based catalysts for C–H bond functionalisation

2021 ◽  
Author(s):  
Yuanhong Ma ◽  
Shao-Jie Lou ◽  
Zhaomin Hou
Keyword(s):  
Review Article ◽  
Current Status ◽  
Comprehensive Overview

This review article provides a comprehensive overview to recognise the current status of electron-deficient boron-based catalysis in C–H functionalisations.

Amino-functional polyethers: versatile, stimuli-responsive polymers

2020 ◽  
Vol 11 (24) ◽  
pp. 3940-3950 ◽  
Author(s):  
Patrick Verkoyen ◽  
Holger Frey
Keyword(s):  
Ring Opening ◽  
Review Article ◽  
Stimuli Responsive ◽  
New Class ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers

Amino-functional polyethers have emerged as a new class of “smart”, i.e. pH- and thermoresponsive materials. This review article summarizes the synthesis and applications of these materials, obtained from ring-opening of suitable epoxide monomers.

Developing Evidence-Based Assessment to Prevent Over- or Underidentification of Disorders for New Language Learners

2020 ◽  
Vol 5 (4) ◽  
pp. 1026-1038
Author(s):  
Sandra Levey ◽  
Li-Rong Lilly Cheng ◽  
Diana Almodovar
Keyword(s):  
Language Learners ◽  
Grade Level ◽  
Reading Skills ◽  
Language Disorder ◽  
Academic Development ◽  
Review Article ◽  
Evidence Based ◽  
Clinical Knowledge ◽  
Language And Literacy ◽  
Support Evidence

Purpose The purpose of this review article is to present certain linguistic domains to consider in the assessment of children learning a new language. Speech-language pathologists frequently face difficulty when determining if a bilingual or multilingual child possesses a true speech or language disorder. Given the increased number of new language learners across the world, clinicians must understand differences versus disorders to prevent underidentification or overidentification of a disorder. Conclusions Early identification of a true disorder has been shown to prevent language and literacy difficulties, given that children are able to achieve grade-level reading skills when given intervention. Clinical knowledge and skills are strongly required so that children receive evidence-based assessment to support their academic development. Learning Goal Readers will gain an understanding of the factors that support evidence-based assessment of bilingual and multilingual language learners.

Treatment Considerations for Adolescents Who Exhibit Cognitive/Communication Problems: A Neuroscience Perspective

2020 ◽  
Vol 5 (6) ◽  
pp. 1767-1775
Author(s):  
Martha S. Burns
Keyword(s):  
Social Communication ◽  
Transition Period ◽  
Clinical Intervention ◽  
Review Article ◽  
Sensitive Period ◽  
Clinical Implications ◽  
Evidence Based ◽  
Communication Problems ◽  
Treatment Considerations ◽  
Behavioral Growth

Purpose Adolescence is a period of substantial neurophysiological and behavioral growth, representing a second sensitive period of brain development. It is a psychological and social transition period between childhood and adulthood with many beneficial changes occurring, especially with respect to potential responsiveness to clinical intervention. However, adolescent behavioral complexities introduce clinical challenges as well. The purpose of this review article is to review the current neuroimaging research on neurophysiological changes observed during adolescence and the cognitive and social behavioral counterparts, with specific attention to the clinical implications. The review article will then summarize currently available intervention tools that can be utilized by speech-language pathologists working with this population. It will conclude with available evidence-based social-communication approaches that may be applicable as well as available evidence-based supplemental technological cognitive interventions that may be useful in working with adolescents who exhibit language and communication issues. Conclusion As a transition period between childhood and adulthood, adolescence represents a second sensitive period during which there is opportunity for clinically derived beneficial cognitive and communication growth.

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