scholarly journals INTESTINAL TUBERCULOSIS

2010 ◽  
Vol 17 (04) ◽  
pp. 532-537
Author(s):  
KHURRAM NIAZ ◽  
MUHAMMAD ASHRAF

Objective: To find out the effective diagnostic algorithm (clinical features and investigations) for intestinal tuberculosis. Design: A retrospective study. Place and Duration of Study: B.V. Hospital Bahawalpur, June 2007 -2009. Patients and Methods: 100 cases of diagnosed abdominal tuberculosis were included in the study. Demographic variables, symptomology, investigations and management detail were recorded from the hospital record of surgical department of B.V. Hospital Bahawalpur. Results: Out of 100 diagnosed cases of intestinal T.B, 55 patients were male. 62 patients were bellow 30 years. Most Common presentation was obstruction (29 %), peritonitis (18%) Abdominal distention (20%) and Abdominal Mass (15%), Histopathology (97%) and laparoscopy (82%) were most sensitive. Operative procedure were right Hemicolectomy (26%), resection Anastomosis (23%), stricturoplasty (13%0, Ileostomy (9%), adhesiolysis (17%). Conservativelymanaged patients on anti-tuberculous therapy (ATT) were (12%). Wound infection and dehiscence (12%) were the common complications. Four patients died. Conclusions: All patients with prolonged history of weight loss, vague health and non specific abdominal symptoms and those who are under consideration for intestinal tuberculosis should follow the protocol comprising histopathology (laparoscopic/ USG guided /open), complemented by the diagnostic laparoscopy and radiological studies. 

2021 ◽  
Vol 2021 ◽  
pp. 1-3
Author(s):  
Michiel L. Sala ◽  
Samuel M. Verhage ◽  
Frank Zijta

Although relatively rare, there is an increasing incidence of abdominal tuberculosis (TB) in the developed countries, with the peritoneum being the most common site of involvement. Manifestation of abdominal TB should be considered in patients with relevant clinical symptoms and risk factors, including a history of prior TB infection and residence in or travel to an area where tuberculosis is endemic. We report a case of intestinal tuberculosis with a complicated disease course after the completion of treatment. Persisting abdominal symptoms during or after treatment should raise suspicion of subclinical intestinal obstruction. Early clinical recognition and surgical treatment may avoid poor outcome due to intestinal perforation.


2016 ◽  
Vol 12 (2) ◽  
Author(s):  
Muzaffar Aziz ◽  
Nasir Jamal ◽  
Muhammad Ikram Farid ◽  
Muzammil Aziz

Objective: To discuss clinical presentations, diagnosis and pattern of intestinal tuberculosis of the patients presenting in surgical department. Design. Retrospective study. Place and duration of study. Nishtar Hospital Multan, Pakistan during the period of January 2002 to August 2004. Patients and methods. 109 diagnosed cases of intestinal tuberculosis were included in this study. Patients with intercurrent illness and patients proved to have other diagnosis after full work up were excluded from the study. A detailed history and full physical examination of all patients was recorded. Later on various investigations, operative findings were also noted. Results. The ages of patients were in range of 12-54 years. Male to female ratio was approximately 1:2. Clinical presentation was quite variable ranging from abdominal pain present in 100 patients (91.74%) to weight loss noted in 54 patients (49.54%). Endoscopic biopsy and PCR analysis were most useful in diagnosing intestinal tuberculosis in elective ca ses. Strictures of the small bowel were commonest pattern noted. Past history of pulmonary tuberculosis was present in 8 patients (7.33%) while 18 patients (16.51%) had previous history of intestinal tuberculosis. 35 patients (32.11%) had positive family history of tuberculosis. 18.34% of the patients had secondary tuberculosis. Conclusion. Intestinal tuberculosis is a common disease in third decade in the developing countries. Females are more affected than males. Primary tuberculosis is more common than secondary tuberculosis. Intestinal tuberculosis may present with a variety of abdominal symptoms and signs. Endoscopy and PCR analysis can be considered as reliable investigation in elective cases. Strictures, mass abdomen and intestinal perforation are the most common pattern observed.


2019 ◽  
Vol 2019 (8) ◽  
Author(s):  
Aghyad K Danial ◽  
Ahmad Al-Mouakeh ◽  
Yaman K Danial ◽  
Ahmad A Nawlo ◽  
Ahmad Khalil ◽  
...  

Abstract Small bowel diaphragm disease is a rare complication related to non-steroidal anti-inflammatory drug (NSAID) use. It presents with non-specific symptoms such as vomiting, abdominal pain, subacute bowel obstruction and occasionally as an acute abdominal condition. We report a case of diaphragm disease in a 33-year-old female who presented with vomiting, constipation and abdominal pain started 5 days earlier. Physical examination revealed palpated abdominal mass. The patient’s past medical history was remarkable for NSAID use. The patient was managed by surgical resection of involved intestine and diagnosis was confirmed by histological examination. Although there are few published cases of diaphragm disease in the medical literature, we recommend that this disease should be considered as one of the differential diagnoses when assessing patients presenting with non-specific abdominal symptoms with remarkable past medical history of NSAID use.


2009 ◽  
Vol 1 (02) ◽  
pp. 056-061 ◽  
Author(s):  
Alakananda Dasgupta ◽  
Navjeevan Singh ◽  
Arati Bhatia

ABSTRACT Background: Along with the increased incidence of pulmonary tuberculosis in parallel with the increase in population in various parts of the world, in recent years, the incidence of abdominal tuberculosis has also increased. The pathogenetic events in intestinal tuberculosis, which culminate in ulcer formation, perforation, and stricture, still have to be identified. Aim: To correlate the gross and microscopic features in intestinal tuberculosis, in particular tuberculous perforation with changes in mesenteric vasculature. Patients and Methods: A one-year prospective study of excised/resected tissues from patients with abdominal tuberculosis requiring surgical intervention was conducted. Tissues from fifty-six patients were included in the study — of which 36 were resected intestinal segments and 20 were intestinal and lymph node biopsies. Hematoxylin and Eosin and Ziehl-Neelsen stains were used for histopathological examination. Results: Tuberculous enteritis was found to be present in 49 of the 56 patients (87.5%) (ileum being the site most commonly affected), while nodal involvement was seen in 39 (69.6%) patients. Perforations were present in 39 out of 49 (79.6%) intestinal tissues; most being solitary and ileum was the commonest site. Typical epithelioid cell granulomas were seen in the intestine and lymph nodes, with caseation being more prevalent in the latter. The mesenteric vasculature was frequently involved by granulomatous inflammation, with intravascular organizing thrombus being present in 30% of the resected specimens with perforation. Acid fast bacilli were demonstrated in the tissue sections of 37.5% of the patients. AFB positivity was higher in caseating granulomas. Conclusion: Involvement of mesenteric vasculature by granulomatous inflammation was commonly associated with the ulcerative type with perforation, suggesting that ischemia caused by vascular thrombosis is responsible for tissue breakdown. This implies that vasculitis plays an important role in the natural history of abdominal tuberculosis.


2022 ◽  
Vol 15 (1) ◽  
pp. e245767
Author(s):  
Damini Saxena ◽  
Robert A Duncan ◽  
Robert R Faust ◽  
Anthony Campagna

Differential diagnosis of a new abdominal mass is broad and includes infection, malignancy and other inflammatory processes. Definitive diagnosis may be challenging without invasive biopsy, as history, physical exam and imaging may be non-specific. A 69-year-old man with a history of abdominal tuberculosis presented with a new painful abdominal cyst consistent with reactivation of tuberculosis versus new malignancy. Investigations revealed 4+ acid-fast bacilli from the aspirate suggestive of tuberculosis, but no improvement was noted on antituberculous therapy. Core needle biopsy noted c-KIT-positive spindle cells, diagnostic for a gastrointestinal stromal tumour, while cultures grew non-tuberculous mycobacteria.


2016 ◽  
Vol 23 (11) ◽  
pp. 1334-1339 ◽  
Author(s):  
Raheel Ahmad ◽  
Muhammad Salman Shafique ◽  
Shahbaz Zafar ◽  
Saqib Mehmood ◽  
Sajid Mehmood ◽  
...  

Tuberculosis is one of the leading causes of morbidity and mortality, responsiblefor annual 7–10 million new cases and 6 per cent of deaths in developing countries. It caninvolve any part of abdomen but most common is intestinal tract in which it can present withwide variety of symptoms. Early diagnosis and appropriate management is challenging forclinicians. Objectives: To determine the modes of presentation of abdominal tuberculosisand effectiveness of surgical procedures in our setup. Study Design: A retrospective study.Setting: Surgical unit-I of Holy Family Hospital, Rawalpindi. Period: January 2014 to December2014. Materials and Methods: 50 patients with abdominal tuberculosis were included inthe study. Histopathology confirmed the diagnosis of abdominal tuberculosis. Age, gender,mode of presentation, evidence of co-existing tuberculosis, family history, drug history of antituberculoustreatment, laboratory and radiological investigations, treatment modalities andduration of hospital stay were recorded. Results: There were 28 female (56%) and 22 male(44%) patients with a mean age of 29± 10.23 years. 56% patients presented with subacuteintestinal obstruction, 16% with acute intestinal obstruction and 14% with peritonitis. All 50patients underwent laparotomy. Ileocecal mass with perforation (40%) was seen as the mostcommon per-operative finding. Limited right hemicolectomy with ileocolostomy (44%) wasperformed in most of the cases. Mean length of hospital stay was 10 ± 4.67 days. Conclusion:Abdominal tuberculosis is a common cause of acute abdomen especially intestinal obstructionin our setup, with a variable mode of presentation. Early diagnosis with appropriate surgicalmanagement and chemotherapy can prevent significant morbidity and mortality.


2019 ◽  
Vol 18 (4) ◽  
pp. 796-800
Author(s):  
Vladimir A Beloborodov ◽  
Elena A Kelchevskaya ◽  
Aleksandr P Frolov ◽  
Darizhab B Tsoktoev ◽  
Igor Y Oleynikov ◽  
...  

Objective: This article presents retrospective analysis conducted on the basis of the General Surgery Clinic of the Irkutsk State Medical University (ISMU). Materials and methods: 165 cases of abdominal tuberculosis (AT) were detected and analyzed. The sample was made from the total number of patients who were treated in the surgical department for urgent reasons from 2009 to 2018. Results and Discussion: Proportion of hospitalized AT cases from the total number increases every year and slightly decreases only after 2013. The largest number of hospitalizations in 2013 was 29 cases or 2.1%. General characteristics are as follows: 95% of patients were 30–35 years old, 93% used drugs, 80% were HIV positive, and 88.3% suffered abdominal pain. Tuberculosis of the gastrointestinal tract with ulcer perforation was more common (53.7%). 140 (84.5%) patients had history of operation. Overall mortality was 57.6%. Conclusion: The main cause of mortality was generalized tuberculosis. The contribution of these cases to the overall mortality over the period taken was not possible to estimate. Bangladesh Journal of Medical Science Vol.18(4) 2019 p.796-800


2017 ◽  
pp. 63-68
Author(s):  
Quoc Phong Le ◽  
Nhu Hiep Pham

Objective: To study the clinical characteristics, paraclinic, the operative indication and treatment outcomes operation of colorectal polyposis by laparoscopic. Marterials: 12 patients with colorectal polyposis, is surgically the subtotal colectomy, and the total colorectomy by laparoscopic from 11/2012 to 4/2015 at Digestive Surgical Department of Hue Central Hospital. Method: Prospective study, all patients were examined clinically, endoscopic colorectal, operative indication, the type of surgery, lengh of post-operative stay, complications, and pathology. Results: From 11/2012 to 4/2015. We had overalled 12 patients: 8 males and 4 females, the mean patient was 36.33 ± 19.5 years of age (15-71). Dyspepsia 66.7%, bloody stools 100%. Laparoscopic segmental bowel resection in four (33,3%) cases: right hemicolectomy in one (8.3%), resection of transverse colon in one (8.3%), left hemicolectomy in two (16.7%), and totally colorectomy in eight (66.7%) by laparoscopic surgery. The mean post-operative hospital stay was 10.1 ± 3.8 days. The early complication: fistula anastomosis in one (8.3%), patients recovered after conservative treatment, no bleeding and no wound infection. The pathology is adematous polyps 91.7% and hyperplasia polyps 8.3%. Conclusion: Laparoscopic surgery is currently the technique of choice. The resection of colorectal polyposis is the method safe, effective, high success, low rate complications. Key words: laparoscopic, polyposis, colo-rectal polyposis, hemicolectomy


2020 ◽  
Vol 20 (2) ◽  
pp. 111-114 ◽  
Author(s):  
Vishal Sharma ◽  
Harjeet Singh ◽  
Harshal S. Mandavdhare

Abdominal tuberculosis is difficult to diagnose due to low sensitivity of microbiological tests and the low histological yield. Satisfactory response to therapy has long been used a criteria for the diagnosis of abdominal tuberculosis. However, the appropriate definitions of response to therapy in abdominal tuberculosis have remained unclear. Recent evidence suggests that mucosal healing of ulcers at the end of therapy or at two months (early mucosal response) is a helpful criteria of response to therapy. This also helps in exclusion of multidrug resistant tuberculosis and alternative diagnosis like Crohn’s disease. Further limited literature suggests the use of some biomarkers like C-reactive protein in the follow-up of patients with peritoneal or intestinal tuberculosis.


2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S119-S119
Author(s):  
Yukihiro Nakanishi ◽  
Preeti Behl ◽  
Byron Crawford

Abstract Pyogenic granuloma also known as lobular capillary hemangioma occurs commonly in the skin and oral mucosa. This entity has been rarely reported in the gastrointestinal tract. We herein report three cases of pyogenic granuloma, located in the duodenum, ileum, and rectum, respectively. Case 1 is a 54-year-old female with a history of angioimmunoblastic T-cell lymphoma who underwent an esophagogastroduodenoscopy for severe heartburn. The endoscopy showed a 13-mm nonbleeding, pedunculated polyp in the second portion of duodenum, which was removed using a hot snare after injection of epinephrine. The patient had an episode of massive gastrointestinal bleeding postpolypectomy, with a significant drop of her hemoglobin, which was managed with blood transfusion. Case 2 is a 68-year-old male with a history of right hemicolectomy due to trauma who had a colonoscopy for chronic diarrhea. The colonoscopy revealed a 14-mm, nonbleeding, pedunculated polyp in the ileum, located 3 cm from the ileocolonic anastomosis. The polyp was removed with hot snare, without complications. Case 3 is a 44-year-old female with morbid obesity who underwent a colonoscopy for iron-deficiency anemia. The colonoscopy showed an 8-mm multilobulated sessile lesion in the distal rectum, which was completely removed using hot snare. No complications were seen postpolypectomy. Histological examination of all the three polyps showed a proliferation of capillary-sized blood vessels with a mixed inflammatory infiltrate, resembling granulation tissue. Additionally, the ileal polyp in our case had marked eosinophilic infiltrate, the etiology of which remains unknown. In conclusion, pyogenic granuloma, given its vascular nature, can be a cause of bleeding in the gastrointestinal tract. Awareness regarding this rare entity is important for its proper diagnosis and treatment.


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