scholarly journals Clinical presentations, diagnosis and pattern of intestinal tuberculosis, our experience, Nishtar Hospital Multan, Pakistan

2016 ◽  
Vol 12 (2) ◽  
Author(s):  
Muzaffar Aziz ◽  
Nasir Jamal ◽  
Muhammad Ikram Farid ◽  
Muzammil Aziz
Keyword(s):  
Positive Family History ◽  
Intestinal Tuberculosis ◽  
Previous History ◽  
Pcr Analysis ◽  
Common Disease ◽  
Female Ratio ◽  
Surgical Department ◽  
Abdominal Symptoms ◽  
Clinical Presentations ◽  
History Of

Objective: To discuss clinical presentations, diagnosis and pattern of intestinal tuberculosis of the patients presenting in surgical department. Design. Retrospective study. Place and duration of study. Nishtar Hospital Multan, Pakistan during the period of January 2002 to August 2004. Patients and methods. 109 diagnosed cases of intestinal tuberculosis were included in this study. Patients with intercurrent illness and patients proved to have other diagnosis after full work up were excluded from the study. A detailed history and full physical examination of all patients was recorded. Later on various investigations, operative findings were also noted. Results. The ages of patients were in range of 12-54 years. Male to female ratio was approximately 1:2. Clinical presentation was quite variable ranging from abdominal pain present in 100 patients (91.74%) to weight loss noted in 54 patients (49.54%). Endoscopic biopsy and PCR analysis were most useful in diagnosing intestinal tuberculosis in elective ca ses. Strictures of the small bowel were commonest pattern noted. Past history of pulmonary tuberculosis was present in 8 patients (7.33%) while 18 patients (16.51%) had previous history of intestinal tuberculosis. 35 patients (32.11%) had positive family history of tuberculosis. 18.34% of the patients had secondary tuberculosis. Conclusion. Intestinal tuberculosis is a common disease in third decade in the developing countries. Females are more affected than males. Primary tuberculosis is more common than secondary tuberculosis. Intestinal tuberculosis may present with a variety of abdominal symptoms and signs. Endoscopy and PCR analysis can be considered as reliable investigation in elective cases. Strictures, mass abdomen and intestinal perforation are the most common pattern observed.

scholarly journals INTESTINAL TUBERCULOSIS

2010 ◽  
Vol 17 (04) ◽  
pp. 532-537
Author(s):  
KHURRAM NIAZ ◽  
MUHAMMAD ASHRAF
Keyword(s):  
Abdominal Mass ◽  
Operative Procedure ◽  
Intestinal Tuberculosis ◽  
Diagnostic Algorithm ◽  
Abdominal Tuberculosis ◽  
Right Hemicolectomy ◽  
Demographic Variables ◽  
Surgical Department ◽  
Abdominal Symptoms ◽  
History Of

Objective: To find out the effective diagnostic algorithm (clinical features and investigations) for intestinal tuberculosis. Design: A retrospective study. Place and Duration of Study: B.V. Hospital Bahawalpur, June 2007 -2009. Patients and Methods: 100 cases of diagnosed abdominal tuberculosis were included in the study. Demographic variables, symptomology, investigations and management detail were recorded from the hospital record of surgical department of B.V. Hospital Bahawalpur. Results: Out of 100 diagnosed cases of intestinal T.B, 55 patients were male. 62 patients were bellow 30 years. Most Common presentation was obstruction (29 %), peritonitis (18%) Abdominal distention (20%) and Abdominal Mass (15%), Histopathology (97%) and laparoscopy (82%) were most sensitive. Operative procedure were right Hemicolectomy (26%), resection Anastomosis (23%), stricturoplasty (13%0, Ileostomy (9%), adhesiolysis (17%). Conservativelymanaged patients on anti-tuberculous therapy (ATT) were (12%). Wound infection and dehiscence (12%) were the common complications. Four patients died. Conclusions: All patients with prolonged history of weight loss, vague health and non specific abdominal symptoms and those who are under consideration for intestinal tuberculosis should follow the protocol comprising histopathology (laparoscopic/ USG guided /open), complemented by the diagnostic laparoscopy and radiological studies. 

scholarly journals HEPATITIS B & C;

2017 ◽  
Vol 24 (02) ◽  
pp. 278-281
Author(s):  
Muhammad Paryal Tagar ◽  
Mujeeb Rehman Abbasi ◽  
Mohammad Rafique Pathan ◽  
Hafeezullah Shaikh
Keyword(s):  
Blood Transfusion ◽  
Hepatitis B ◽  
Road Traffic ◽  
Previous History ◽  
Case Series ◽  
Previous Surgery ◽  
Female Ratio ◽  
Surgical Department ◽  
The Social ◽  
History Of

Objectives: To determine the frequency of hepatitis b & c viral infection insurgical patients. Study Design: Descriptive case series. Place and Duration of Study: Thisstudy was conducted at surgical department of multiple hospitals and compares the results,JPMC Karachi, Civil Hospital Naushahro Feroze and Jamshoro, Pakistan from August 2014 toDecember 2015. Methodology: All 2645 patients were admitted for emergency and electivesurgery. All patients taken detail history regarding demographic parameter and risk factorslike previous surgery, blood transfusion, barbar, Road Traffic accident, haemodialysis, Tattoos/body piercing, injecting drug user, family history of hepatitis, previous history of jaundiceand Hospitalization. Hospital laboratory was used for screened HBsAg and Anti HCV usingimmunochromatography (ICT method). Patients excluded who were those did not need thesurgery or known case of HBsAg and Anti HCV. Data collected was entered into and analyzedby using statistical package for the social science – 20. Results: Out of 2645 patients, maleto female ratio were 1.9:1. The mean age was 40.2+6.12years (20 to 60 years). Out of 2645patients, Anti HCV was positive in 288(10.88%) cases followed by HBsAg was in 152(5.74%)cases. While both positive in 36 (1.36%) cases. We observed Previous surgery was main riskfactor in the reactive 156(32.77%) cases followed by Barbar, Blood transfusion were 74(15.54%)and 47(9.87%) respectively. Conclusion: We conclude that preoperatively screening of hepatitisB and C should be performed.

Epidemiological Profile and Postpartum Outcome for Severe Preeclamptic Patients

2021 ◽  
pp. 45-50
Author(s):  
Suher Dafaus ◽  
Amel Morgham ◽  
Nasreen Osman
Keyword(s):  
Caesarean Section ◽  
Positive Family History ◽  
Previous History ◽  
Severe Preeclampsia ◽  
Intrauterine Fetal Death ◽  
Chronic Hypertension ◽  
Hypertensive Disorder ◽  
Adequate Treatment ◽  
History Of ◽  
The Mean

Background and objective. Preeclampsia is a multisystemic disorder, which involves the placenta, liver, blood, neurological and cardiovascular systems. It is one of the leading causes of maternal and fetal morbidity and mortality. This study aimed at describing the characteristic features for mothers who had severe preeclampsia and to know the complications during puerperium. Methods. A prospective study conducted over a period from February 2009 up to November 2009 involving 100 pre-eclampsia patients admitted and delivered in Aljalaa Maternity Hospital, Tripoli, Libya. Results. The patients mean age was 33.3 +5.9 years. The mean gestational age at admission time was 36.8+3.2 weeks and 64% of them were term. 58% of the patients with severe preeclampsia had a positive family history of chronic hypertension whereas 42% of patients had a previous history of preeclampsia. 40% of patients were primigravida. The mean systolic blood pressure at admission was 164+15.4 mmHg and the mean diastolic pressure was 113+6 mmHg. The common symptoms were headache, abdominal pain, and blurred vision (54%, 37%, and 31% respectively), whereas 9% of the patients presented with the eclamptic fit. The pregnancy in 66% patients ended by caesarean section, 78% of them were emergency caesarean section. The birth weight of 13% of new-borns was less than 1500 grams. Furthermore, 10% diagnosed with intrauterine fetal death (IUFD) antenatally and 9% died after admission to nursery intensive care unit post-delivery. Conclusion. the effects of hypertensive disorder associated with pregnancy could be prevented by close antenatal care particularly for whose had previous history of preeclampsia. In addition; early recognition and adequate treatment, and timely delivery can prevent preeclampsia and will improve maternal and neonatal outcomes.

scholarly journals Comparison of Maternal and Fetal Outcomes in Parturients With and Without a Diagnosis of Gestational Diabetes

2019 ◽  
Vol 41 (11) ◽  
pp. 647-653 ◽  
Author(s):  
Inês Carolina Siqueira Freitas ◽  
Micheli Cristiane Hintz ◽  
Larissa Chaiane Orth ◽  
Tamara Gonçalves da Rosa ◽  
Betine Moehlecke Iser ◽  
...  
Keyword(s):  
Family History ◽  
Gestational Diabetes ◽  
Statistical Significance ◽  
Positive Family History ◽  
Previous History ◽  
Diabetes Diagnosis ◽  
Fetal Outcomes ◽  
Family History Of Diabetes ◽  
Significant Difference ◽  
History Of

Abstract Objective The present study aims to compare the maternal and fetal outcomes of parturients with and without a gestational diabetes diagnosis. Methods A case-control study including parturients with (cases) and without (control) a gestational diabetes diagnosis, who delivered at a teaching hospital in Southern Brazil, between May and August 2018. Primary and secondary data were used. Bivariate analysis and a backward conditional multivariate logistic regression were used to make comparisons between cases and controls, which were expressed by odds ratio (OR), with a 95% confidence interval (95%CI) and a statistical significance level of 5%. Results The cases (n = 47) were more likely to be 35 years old or older compared with the controls (n = 93) (p < 0.001). The cases had 2.56 times greater chance of being overweight (p = 0.014), and a 2.57 times greater chance of having a positive family history of diabetes mellitus (p = 0.01). There was no significant difference regarding weight gain, presence of a previous history of gestational diabetes, height, or delivery route. The mean weight at birth was significantly higher in the infants of mothers diagnosed with diabetes (p = 0.01). There was a 4.7 times greater chance of macrosomia (p < 0.001) and a 5.4 times greater chance of neonatal hypoglycemia (p = 0.01) in the infants of mothers with gestational diabetes. Conclusion Therefore, maternal age, family history of type 2 diabetes, obesity and pregestational overweightness are important associated factors for a higher chance of developing gestational diabetes.

scholarly journals Metabolic Risk Factors and Outcomes in Acute Coronary Syndrome

2020 ◽  
pp. 46-50
Author(s):  
Ritu Attri ◽  
Harsimran Kaur ◽  
Raminderpal Singh Sibia ◽  
Mandip Singh Bhatia
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Positive Family History ◽  
Developed Countries ◽  
P Value ◽  
Health Crisis ◽  
Female Ratio ◽  
Medical College ◽  
Coronary Syndrome ◽  
History Of

Introduction: CAD is the most common cause of mortality in India. It is a common multifarious public health crisis today and a leading cause of morbidity and mortality in both developing and developed countries. Hence, understanding the predominant risk factors among the Indian population is important. Materials and Methods: This was a hospital based age and sex matched case control study, carried out at Government Medical College and Rajindra Hospital Patiala. A total of 100 patients of Acute coronary syndrome were studied. Patients and controls were enquired about  the presence of cardiometabolic risk factors and the significance of association of these risk factors with the occurrence of Acute coronary syndrome was given by p value of  <0.05. Results: Majority of the cases were in the age group 61-70 years (32%) with male to female ratio  of 1.25:1. Significant association was found between ACS and risk factors like smoking, positive family history of IHD, hypertension, diabetes, dyslipidemia, waist hip ratio and body mass index. Overall, most common outcome of ACS in the present study was NSTEMI (45%) followed by STEMI (35%) followed by Unstable angina (20%). Conclusion: Significant association was found between smoking and occurrence of STEMI and significant association was found between Hypertension and occurrence of NSTEMI.

scholarly journals ACUTE MYOCARDIAL INFARCTION;

2014 ◽  
Vol 21 (06) ◽  
pp. 1200-1203
Author(s):  
Shahzad Alam Khan ◽  
Sohail Safdar ◽  
Asna Ijaz ◽  
Ijaz-Ul-Haque Taseer
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Family History ◽  
Positive Family History ◽  
Descriptive Study ◽  
Research Centre ◽  
Female Ratio ◽  
First Degree Relatives ◽  
History Of

Objective: To determine the frequency of family history of IHD and related risk factors in the first degree relatives of patients suffered from acute myocardial infarction (AMI). Study Design: Descriptive study. Setting: PMRC Research Centre, Nishtar Medical College, Multan, Cardiology unit Nishtar Hospital Multan and Chaudhry Pervez Elahi Institute of Cardiology, Multan. Duration: One year from July 2011 to June 2012. Material and methods: In this descriptive study 331 patients of AMI of either sex and age ≥ 20 years admitted in Cardiology unit of Nishtar Hospital Multan and Chaudhary Pervez Elahi Institute of Cardiology Multan were registered. For data collection non-probability convenient sampling technique was used. Informed consent was taken from each patient. The information were recorded in a pre-designed questionnaire. The data were analyzed through SPSS-11. Results: Mean age of the study cases was 54.99±11.25 years (Minimum age was 20 years and maximum was 90 years). Two hundred sixty four (79.8%) were male and 67 (20.2%) were female patients and male to female ratio was 3.9:1. Out of these 331 patients 111 (33.6 %) were having positive family history of IHD. In these 111 (33.6 %) cases history of diabetes was seen in 45 (40.5 %), 43(38.8 %) had history of hypertension and history of hyper-cholesterolemia was present in 23 (20.7 %) of cases. Conclusions: The family history of IHD in addition to traditional risk factors such as hypertension, hyperlipidemia, diabetes mellitus and smoking is itself an important risk factor for IHD. Relatives of the young patients with IHD should be considered as high risk group and it calls for close surveillance of their first degree relatives and early intervention. All their family members should be advised life style modification, appropriate management of risk factors and regular follow up of even apparently healthy descendents.

scholarly journals Fasting Blood Glucose Profile among Secondary School Adolescents in Ado-Ekiti, Nigeria

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
I. O. Oluwayemi ◽  
S. J. Brink ◽  
E. E. Oyenusi ◽  
O. A. Oduwole ◽  
M. A. Oluwayemi
Keyword(s):  
Blood Glucose ◽  
Family History ◽  
Secondary School ◽  
Fasting Blood Glucose ◽  
Positive Family History ◽  
Cross Sectional ◽  
Female Ratio ◽  
History Of ◽  
History Of Obesity ◽  
The Impact

Background.Over the past two decades there has been an increase in type 2 diabetes mellitus (T2DM) in children. Baseline data is needed to assess the impact of changing lifestyles on Ado-Ekiti, a previously semiurban community in Southwest Nigeria. This study was therefore conducted to assess the fasting blood glucose (FBG) of adolescents in Ado-Ekiti, Nigeria.Methodology.This was a cross-sectional study involving 628 adolescents from three different secondary schools in Ado-Ekiti, Nigeria. With parental consent, volunteers completed a structured questionnaire, and an overnight FBG was measured.Results.There were 346 males and 282 females (male : female ratio = 1.2 : 1). Their ages ranged from 10 to 19 years (mean age:14.2±1.7years). Four hundred and forty-four (70.7%) had normal FBG, while 180 (28.7%) and 4 (0.6%) had FBG in the prediabetic and diabetic range, respectively. Female gender, age group 10–14 years, and family history of obesity were significantly associated with impaired FBG (Pvalue <0.001, <0.001, and 0.045, resp.).Conclusion.Impaired FBG is common among secondary school adolescents and it is more prevalent among younger female adolescents (10–14 years) with positive family history of obesity.

Parasuicidal poisoning treated in a Greek medical ward: epidemiology and clinical experience

2001 ◽  
Vol 20 (12) ◽  
pp. 611-617 ◽  
Author(s):  
A I Hatzitolios ◽  
M L Sion ◽  
N P Eleftheriadis ◽  
E Toulis ◽  
G Efstratiadis ◽  
...  
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Previous History ◽  
Case Series ◽  
Acute Poisoning ◽  
Northern Europe ◽  
Female Ratio ◽  
History Of ◽  
The Mean ◽  
Prospective Case Series

Objective: To study the epidemiology of acute poisoning patients presenting to an acute medical service ward in a Greek hospital between January 1998 and December 2000. Design: Prospective case series. Results: A total of 273 patients with self-poisoning were included in the study. This represented 3.8% of the overall admissions to the unit. The mean age of patients was 33, the most frequent age group being that aged 20–30 years (36.2% of total) with a male-to-female ratio of 1:1.97. Sixty per cent of patients was admitted within 4 h. Those from urban areas comprised 76.2% and 23.8% from rural areas. The most frequently ingested agents were psychopharmaceuticals (37.4%) and analgesics/anti-rheumatics (32.6%). Pesticides (7.7% of total) were most frequently used by patients coming from rural areas (32.3% of patients from rural areas). Alcohol was included in the overdose in 8.4%. Of the patients, 16.2% had a previous history of overdose. In this case series, psychiatric assessment suggested that 52% of the patients had a formal psychotic diagnosis, 21% had personality disorder and 27% had taken an overdose in response to stress. The most frequently documented precipitating factors were family problems and disputes (37%). Unusually, the seasonal distribution in these patients suggested a peak in summer (37.5% of presentations) with lower numbers in spring (30.2%), autumn (17.7%) and winter (14.6%). Of the patients, 23.7% presented in July. A total of 73.5% of patients was conscious, 16.4% was somnolent, 4.5% was in precoma and 5.6% was in coma (GCS <8). Patients who received antidotal therapy comprised 17.9%. Evidence of hepatic dysfunction was observed in 8.9% of patients and renal dysfunction in 3.6%. Extracorporeal techniques for drug removal (hemodialysis and hemoperfusion) were used in 2.2% of patients. Intensive care therapy was required in 11.4% of patients. The mean overall hospitalization time was 3.3 days. The mortality rate was 2.9%. Conclusions: This study shows that the epidemiology of self-harm by overdose in Greece is significantly different in terms of the seasonal presentation from other parts of Europe. The agents ingested and other features are similar to northern Europe. Psychiatric diagnoses are more common in our group than in those reported from northern Europe.

scholarly journals Impact of Family History on Acute Appendicitis – An Iraqi Study at Baghdad Teaching Hospital

2018 ◽  
Vol 6 (2) ◽  
pp. 47-51
Author(s):  
Tabarek Yaseen ◽  
Zahraa Qais ◽  
Zahraa Abass
Keyword(s):  
Abdominal Pain ◽  
Family History ◽  
Acute Appendicitis ◽  
Acute Abdominal Pain ◽  
Positive Family History ◽  
Primary Analysis ◽  
Surgical Department ◽  
History Of ◽  
The Impact ◽  
Diagnostic Setting

Background: Appendicitis is one of the most common causes of the acute abdomen worldwide, but many patients present with atypical signs and symptoms. The study aimed to evaluate the impact of positive family history in the diagnosis of appendicitis in a limited diagnostic setting. Methods: Gender matched case control study of ratio (1:2) was carried out from July 2016 to September 2016 with a sample size of 300 patients. Cases were patients presented in surgical department with acute abdominal pain diagnosed as having appendicitis for whom appendectomy was performed, while controls were hospital based with other abdominal problems. Data was collected using a questionnaire. Primary analysis was a Chi square (χ2) test and the calculation of odds ratio (OR) for the association between final diagnosis of appendicitis and family history. Results: Females were 55% in both groups. Cases were younger than controls (27.05± 12.58 vs. 42.43±17.39 years). Positive family history of appendectomy was higher among cases (66%) than controls (31.5%). The diagnosis of acute appendicitis was 3.8 times higher among those with positive family history of appendectomy and abdominal pain, with a sensitivity of 66% and a specificity of 66.4%. Cases with more than one relative with family history of appendectomy, increased suspicion by 13 times when compared to those without family history. Conclusion: Positive family history of appendectomy in patients with acute abdominal pain and more than one relative with history of appendicitis can be considered as important parameters in the diagnosis of appendicitis in limited diagnostic setting.

scholarly journals Case of Metastatic Malignant Melanoma Simulating Granuloma Annulare

2021 ◽  
Vol 5 (3) ◽  
pp. 289-292
Author(s):  
Haley Danielle Heibel ◽  
Parneet Dhaliwal ◽  
Etan Marks ◽  
Clay J. Cockerell
Keyword(s):  
Malignant Melanoma ◽  
Metastatic Melanoma ◽  
Immunohistochemical Staining ◽  
Previous History ◽  
Metastatic Malignant Melanoma ◽  
Granuloma Annulare ◽  
Diagnostic Challenge ◽  
Clinical Presentations ◽  
History Of ◽  
High Index Of Suspicion

Malignant melanoma and particularly metastatic melanoma represent a diagnostic challenge due to the wide variety of histologic patterns, resemblance to benign entities, and extensive range of clinical presentations.  A high index of suspicion for melanoma is important for accurate diagnosis, especially when there is a previous history of malignancy.  Here, we present a patient with a history of melanoma and locally metastatic melanoma, who subsequently developed a nodule on his right forearm near the site of his previous melanoma excision.  Histologically, the melanoma appeared as granuloma annulare (GA) with benign cytologic features, but was identified as metastatic melanoma using SOX-10 immunohistochemical staining.  Other malignancies, including lymphomas, leukemias, sarcomas, and cutaneous metastases of internal malignancies, have mimicked GA and interstitial granulomatous processes.  Therefore, further immunohistochemical staining should be performed to assess for metastatic disease in the setting of a histological pattern that resembles a benign granulomatous process in a patient with a history of malignancy, including malignant melanoma.

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