scholarly journals VACCINATED HEMODIALYSIS PATIENTS

2016 ◽  
Vol 23 (04) ◽  
pp. 396-400
Author(s):  
Ahsan Mobin ◽  
Fawed Qureshi ◽  
Muhammad Umar Khan ◽  
Rakhshinda Jabeen
Keyword(s):  
Hepatitis B ◽  
Past History ◽  
Immunosuppressive Agents ◽  
Tertiary Care ◽  
Hemodialysis Patients ◽  
Hepatitis B Vaccination ◽  
Weekly Schedule ◽  
Care Hospital ◽  
Excellent Response ◽  
Study Results

Objectives: Determine the status of immunity against the hepatitis B virus amongvaccinated hemodialysis patients at a tertiary care hospital. Study Design: Cross sectionalstudy. Place and Duration of Study: All medical wards of Civil Hospital and Ojha campus, DowUniversity of Health Sciences, Karachi, Pakistan from May 2013 to January 2015. Methodology:Patients with chronic kidney disease on hemodialysis attending out-patient department wereenrolled. Patients with either gender and aged 18-70 years, who give consent for participation,who are on HD for more than 9 months with a proven diagnosis of ESRD who have receiveda complete course of 4 doses of hepatitis B vaccination atleast 2 months back were includedin this study. Non-consenting patients, present/past history of viral hepatitis, patients whowere hepatitis B surface antigen (HBsAg) positive, patients on immunosuppressive agents,pregnant patients were excluded from this study. Results: Out of the 103 patients, 69 (67%)males and 34 (33%) females with mean age of study population was 51.1 ± 14.3 years (17 to70 years), mean duration post vaccination was 7.6 ± 0.9 months (6 to 9 months), mean antiHBs antibody level was 184.6 ± 293.4 (level rang 0 to 1000) and mean hemodialysis durationwas 26.4 ± 12 months (10 to 50 month). Out of 37 non-responders 28 (75.7%) had twice weeklyschedule of hemodialysis and 09 (24.3%) had thrice weekly schedule of hemodialysis, out of 19weak responders 13 (68.4%) had twice weekly schedule of hemodialysis and 06 (31.6%) hadthrice weekly schedule of hemodialysis and out of 47 high responders 29 (61.7%) had twiceweekly schedule of hemodialysis and 18 (38.3%) had thrice weekly schedule of hemodialysis(p=0.395). Conclusion: Excellent response of HbsAg B vaccination for those patients, undergodialysis procedure that is not associated with age, systemic inflammation or nutritional. Effectivedialysis procedure associated with excellent response to the vaccine hepatitis B.

scholarly journals Hepatitis B vaccination coverage among health care workers in rural Kerala

2021 ◽  
Vol 8 (7) ◽  
pp. 3489
Author(s):  
Vani Srinivas ◽  
Tess Shajan ◽  
Sudheesh Muthuthodiyil Karippankunnath ◽  
Theertha Pradeep Reshmi ◽  
Vidhu Victor ◽  
...  
Keyword(s):  
Health Care ◽  
Hepatitis B ◽  
Vaccination Coverage ◽  
Health Care Workers ◽  
Vaccine Coverage ◽  
Tertiary Care ◽  
Hepatitis B Vaccine ◽  
Hepatitis B Vaccination ◽  
Care Hospital ◽  
Care Workers

Background: Hepatitis B is one of the most important blood borne infection, the health care workers may acquire while providing care to the patients. The overall aim of this study was to estimate the Hepatitis B vaccine coverage and its determinants among health care workers.Methods: This cross-sectional study was done in a rural tertiary care hospital in Palakkad district, of Kerala. We particularly looked for self-reported hepatitis B vaccination coverage and its determinants, using self-administered pretested questionnaire in 410 health workers. We calculated the proportions and looked for association between the various independent variables and dependent variables for vaccination coverage.Results: Out of 410 study participants, 119 (29%) of them were males and 291 (71%) of them were females. The mean age of the participant was 31.3 years and the range was between 19 to 70 years. 365 (89%) were vaccinated with atleast one dose of Hepatitis B Vaccine. Of these 306 (74.6%) had received all the 3 doses of vaccine, as per schedule. Gender and years of experience was not associated with the Hepatitis B vaccination status. However, variables like educational status, professional background was associated with hepatitis B vaccine coverage.Conclusions: The coverage of hepatitis B vaccine was high. Among those with incomplete vaccination few of them were waiting for completing the vaccination schedule in near future. Good hospital policies like vaccinating the new medical students and new employees were the main factors responsible for high vaccination coverage among the health care workers in our study.

scholarly journals Hepatitis B vaccination status among healthcare workers in a tertiary care hospital in Tripoli, Libya

2013 ◽  
Vol 6 (4) ◽  
pp. 246-251 ◽  
Author(s):  
Hisham Ziglam ◽  
Mabrouk El-Hattab ◽  
Noura Shingheer ◽  
Abdulaziz Zorgani ◽  
Omar Elahmer
Keyword(s):  
Hepatitis B ◽  
Healthcare Workers ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Vaccination Status ◽  
Hepatitis B Vaccination ◽  
Care Hospital

SEROPREVALENCE OF HIV AND HBsAg AMONGST BLOOD DONORS IN A TERTIARY CARE HOSPITAL, CHHATTISGARH.

2019 ◽  
Vol 3 (8) ◽  
Author(s):  
Anusha P ◽  
Bankar Nandkishor J ◽  
Karan Jain ◽  
Ramdas Brahmane ◽  
Dhrubha Hari Chandi
Keyword(s):  
Hepatitis B ◽  
Blood Donors ◽  
Hepatitis B Surface Antigen ◽  
Tertiary Care ◽  
Laboratory Diagnosis ◽  
Blood Bank ◽  
Care Hospital ◽  
Medical College ◽  
The World ◽  
First Time

INTRODUCTION: India being the second highly populated nation in the world. HIV/AIDS has acquired pandemic proportion in the world. Estimate by WHO for current infection rate in Asia. India has the third largest HIV epidemic in the world. HIV prevalence in the age group 15-49 yrs was an estimate of 0.2%. India has been classified as an intermediate in the Hepatitis B Virus (HBV) endemic (HBsAg carriage 2-7%) zone with the second largest global pool of chronic HBV infections. Safety assessment of the blood supply, the quality of screening measures and the risk of transfusion transmitted infectious diseases (TTIs) in any country can be estimated by scrutinizing the files of blood donors. After the introduction of the blood banks and improved storage facilities, it became more extensively used. Blood is one of the major sources of TTIs like hepatitis B, hepatitis C, HIV, syphilis, and many other blood borne diseases. Disclosure of these threats brought a dramatic change in attitude of physicians and patients about blood transfusion. The objective of this study is to determine the seroprevalence of transfusion transmitted infections amidst voluntary blood donors at a rural tertiary healthcare teaching hospital in Chhattisgarh. MATERIAL AND METHODS: This retrospective study was carried out in Chandulal Chandrakar Memorial Medical College, Kachandur, Durg. Blood donors were volunteers, or and commercial donors who donated the blood and paid by patients, their families, or friends to replace blood used or expected to be used for patients from the blood bank of the hospital. After proper donation of blood routine screening of blood was carried out according to standard protocol. Laboratory diagnosis of HIV 1 and HIV 2 was carried out by ELISA test. Hepatitis B surface antigen was screened by using ELISA. RESULTS: A total of 1915 consecutive blood donors’ sera were screened at Chandulal Chandrakar Memorial Medical College, blood bank during study period. Of these 1914 were male and 1 female. The mean age of patients was found to be 29.34 years with standard deviation (SD) of 11.65 Years. Among all blood donors in present study, 759(39.63%) were first time donors and 1156(60.37%) were repeated donors. 1 patient was HIV positive in first donation group while 3 (75%) were positive in repeat donation group. 7 (38.9%) were HBsAg positive in in first donation group while 11(61.1%) were positive in repeat donation group. Two patients in first donation group had dual infection of HIV and HBsAg. CONCLUSION: Seropositivity was high in repeated donors as compared to first time donors. The incidence of HIV is observed to be 0.2% and that of HBsAg is 0.94%. Strict selection of blood donors should be done to avoid transfusion-transmissible infections during the window period.

scholarly journals Relationship between trajectories of post-stroke disability and self-rated health (NeuroAdapt): protocol for a prospective observational study

BMJ Open ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. e049944
Author(s):  
Sarah K Schäfer ◽  
Robert Fleischmann ◽  
Bettina von Sarnowski ◽  
Dominic Bläsing ◽  
Agnes Flöel ◽  
...  
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Functional Health ◽  
Care Hospital ◽  
Duration Of Symptoms ◽  
Post Stroke ◽  
Self Rated Health ◽  
Modifying Factors ◽  
Study Results

IntroductionStroke is the leading neurological cause of adult long-term disability in Europe. Even though functional consequences directly related to neurological impairment are well studied, post-stroke trajectories of functional health according to the International Classification of Functioning, Disability and Health are poorly understood. Particularly, no study investigated the relationship between post-stroke trajectories of activities of daily living (ADL) and self-rated health (SRH). However, such knowledge is of major importance to identify patients at risk of unfavourable courses. This prospective observational study aims to investigate trajectories of ADL and SRH, and their modifying factors in the course of the first year after stroke.Methods and analysisThe study will consecutively enrol 300 patients admitted to a tertiary care hospital with acute ischaemic stroke or transient ischaemic attack (TIA; Age, Blood Pressure, Clinical Features, Duration of symptoms, Diabetes score ≥3). Patient inclusion is planned from May 2021 to September 2022. All participants will complete an interview assessing ADL, SRH, mental health, views on ageing and resilience-related concepts. Participants will be interviewed face-to-face 1–5 days post-stroke/TIA in the hospital; and will be followed up after 6 weeks, 3 months, 6 months and 12 months via telephone. The 12-month follow-up will also include a neurological assessment. Primary endpoints are ADL operationalised by modified Rankin Scale scores and SRH. Secondary outcomes are further measures of ADL, functional health, physical activity, falls and fatigue. Views on ageing, social support, resilience-related concepts, affect, frailty, illness perceptions and loneliness will be examined as modifying factors. Analyses will investigate the bidirectional relationship between SRH and ADL using bivariate latent change score models.Ethics and disseminationThe study has been approved by the institutional review board of the University Medicine Greifswald (Ref. BB 237/20). The results will be disseminated through scientific publications, conferences and media. Moreover, study results and potential implications will be discussed with patient representatives.Trial registration numberNCT04704635.

scholarly journals ANTIMICROBIAL-RELATED ADVERSE DRUG REACTION IN A TERTIARY CARE HOSPITAL

2017 ◽  
Vol 10 (8) ◽  
pp. 229
Author(s):  
Jindal M ◽  
Sharma Rk
Keyword(s):  
Adverse Drug Reaction ◽  
Drug Reaction ◽  
Spontaneous Reporting ◽  
Tertiary Care Hospital ◽  
Past History ◽  
Tertiary Care ◽  
Care Hospital ◽  
Beta Lactam ◽  
Active Monitoring ◽  
Beta Lactam Antibiotics

  Objective: The objective of the study was to evaluate the adverse drug reaction (ADR) related to commonly used antimicrobials in a tertiary care hospital.Methods: A prospective spontaneous reporting study involving, active methods (pharmacist actively looking for suspected ADRs) and passive methods (stimulating prescribers to report suspected ADRs) was carried out in all departments of a tertiary care hospital, for 1 year. Patients of all age groups were included in the study. The data for the study were taken from case sheets, investigation reports of patients who had experienced an ADR, personal interviews with reporting persons or clinicians, personal interviews with patient or patient’s attendant, past history of medication use, which were generally obtained from, prescriptions from the past, reports of medical and surgical interventions, referral letters, ADR reporting forms. Collected data were then analyze for causality assessment by Naranjo’s scale and severity assessment by Hartwig and Siegel’s scale.Result: During 1 year of study period, 75 ADRs related to antimicrobial were reported among 1354 patients who were given antibiotic for the treatment. The incidence rate of antibiotic was found to be 5.53%. The department that reported ADR was medicine (10.16%), ENT (4.6%), pediatric (8.12%), orthopedics (06.9%), surgery (06.9%), chest and tuberculosis (04.6%), obstetrics and gynecology (06.9%), dentistry (02.3%), and skin (10.16%). The most common ADRs were related to gastrointestinal tract; dermatological reactions were second in the list of antimicrobial drugs causing ADR. In this study, among antimicrobials, fluoroquinolones, and beta-lactam antibiotics were the most common drugs causing gastrointestinal and dermatological ADRs. There was no unknown ADR reported that may need to be further investigated through active monitoring. All patients recovered from ADRs without any complications. The causality was assessed by Naranjo’s scale and it revealed that out of 75 antibiotics related ADR 48 (64%) were possible, 27 (36%) were probable, 3 (4.00%) were definate, and 0% were unlikely. According to the Hartwig and Siegel’s scale, most of ADR were mild 45 (60%) and moderate 30 (40%) in nature.Conclusion: ADRs related to antimicrobials occurs frequently. Among antimicrobials, fluoroquinolones, and beta-lactam antibiotics were the most common drugs causing gastrointestinal and dermatological ADRs. The health-care system can promote the spontaneous reporting of antimicrobial ADR to pharmacovigilance center for ensuring safe drug use and patient care.

scholarly journals Halitosis: Its Aetiology and Psychosocial Impact- A Hospital Based Study

2021 ◽  
Vol 29 (2) ◽  
pp. 145-150
Author(s):  
Gopika Kalsotra ◽  
Monica Manhas ◽  
Sachin Gupta ◽  
Heemani Bhardwaj ◽  
Parmod Kalsotra ◽  
...  
Keyword(s):  
Social Life ◽  
Laryngopharyngeal Reflux ◽  
Systemic Disease ◽  
Tertiary Care ◽  
Neck Surgery ◽  
Psychosocial Impact ◽  
Care Hospital ◽  
Female Ratio ◽  
Study Results ◽  
A Prospective Study

Introduction Halitosis means bad or unpleasant odour from oral cavity. It causes embarrassment to the patients and affects their social life and communication. This study aims to find the causes of halitosis and to assess its psychosocial impact. Materials and Methods A prospective study was conducted in the department of Otorhinolaryngology and Head Neck Surgery in a tertiary care hospital. It included 165 patients, presenting to the ENT OPD with chief complains of oral malodour for at least 3 months. The patients in the age above 15 years and below 75 years, irrespective of gender, were included in the study. Results The age of the patients ranged from 15 to 75 years with a mean age of 52.24 ± 15.67 with male: female ratio of 7:10. The most common cause of halitosis in the present study included chronic rhinosinusitis (38.7%), gingivitis/periodontitis (19.39%), tonsillitis (4.84%), laryngopharyngeal reflux (2%), deep neck space infections (1.2%). In 23.56%, the halitosis was a symptom of an underlying malignancy. Conclusion Halitosis from an extra oral origin can be the sign of an underlying systemic disease or malignancy. The consultation should be done with the periodontist, ENT specialist and a physician.

scholarly journals Hepatitis B Virus Infection: Knowledge and Awareness Among the Patients Admitted in a Tertiary Care Hospital in Bangladesh

2019 ◽  
Vol 25 (1) ◽  
pp. 6-13
Author(s):  
Nahida Zafrin ◽  
M.A. Sattar Sarkar ◽  
Md. Motlabur Rahman ◽  
Umma Salma ◽  
Tania Mahbub ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Hepatitis B Virus Infection ◽  
B Virus
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