Bacteriology and antibiotic sensitivity pattern of ear discharge in patients with chronic otitis media; A cross sectional study conducted in tertiary care hospital of Peshawar.

2021 ◽  
Vol 28 (05) ◽  
pp. 671-676
Author(s):  
Mubassir Ullah ◽  
Muhammad Saleh Faisal ◽  
Ali Zaki ◽  
Azam Khan ◽  
Mamoor Khan ◽  
...  
Keyword(s):  
Otitis Media ◽  
Proteus Mirabilis ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Bacterial Isolates ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sensitivity Pattern ◽  
Klebsiella Spp

Objective: To determine the frequency of common bacteria and antibiotic sensitivity pattern of ear discharge in patients with chronic otitis media. Study Design: Descriptive Cross Sectional study. Setting: Department of ENT, Northwest General Hospital & Research Centre, Peshawar. Period: February to September 2019. Material & Methods: A total of 196 patients of both gender and age between 13 to 60 years with clinical diagnosis of active chronic otitis media were recruited through consecutive sampling technique. After detailed history and relevant examination, demographic data was recorded and pus specimens were collected from the infected ear on cotton swabs. They were sent to pathology laboratory of hospital for culture of common bacteria (E.coli, Pseudomonas aueroginosa, Proteus mirabilis, Staphylococcus aureus and Klebsiella spp) and their respective antibiotic sensitivity (Co-trimoxazole, Co-Amoxiclav, Ciprofloxacin, Ampicillin, Imipenem, Ceftriaxone and Cefixime). Results: Bacterial isolates were analyzed as 48% Staph aureus, 28% Pseudomonas, 12% Proteus mirabilis, 8% E. coli and 4% Klebsiella spp. Imipenem was sensitive to 94%, ceftriaxone 84%, ciprofloxacin 80%, co-trimoxazole 66%, ampicillin 63%, cefixime 45% and co-amoxiclav against 43% of total bacterial isolates. Conclusion: The common causative organism for active chronic otitis media was Staph aureus followed by Pseudomonas. Imipenem was the most sensitive antibiotic against majority of bacterial isolates followed by ceftriaxone and ciprofloxacin.

scholarly journals Frequency of gram negative bacterial isolates in chronic suppurative otitis media and their sensitivity pattern.

2021 ◽  
Vol 28 (08) ◽  
pp. 1196-1199
Author(s):  
Saeeda Nabat ul Hassan ◽  
◽  
Khushbu Farva ◽  
Ghulam Asghar Bhutta ◽  
◽  
...  
Keyword(s):  
Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Chronic Suppurative Otitis Media ◽  
Ethical Review ◽  
Bacterial Isolates ◽  
Cross Sectional ◽  
Suppurative Otitis Media ◽  
Gram Negative ◽  
Sensitivity Pattern

Objective: To determine frequency of gram negative bacterial isolates and their antibiotic sensitivity pattern among patients with chronic suppurative otitis media. Study Design: Descriptive Cross Sectional study. Setting: Department of Pathology Sahara Medical College Narowal. Period: January 2020 to June 2020. Material & Methods: Total 126 bacterial isolates were taken from the patients having unilateral or bilateral ear discharge reporting to OPD or emergency department during study period. After taking detailed history, examination and baseline investigations diagnosis was confirmed. Specimens of ear discharge were taken from all patients and sent to the pathology department of study institution to determine culture and sensitivity pattern of Gram-negative bacterial isolates. Consent was taken from ethical review committee. Data was analyzed on SPSS-24. Chi square test was applied on collected data. Results: Bacterial isolates were taken from 126 cases having age 2-54 years with mean age of 11.45±5.73 years of either gender. Mostly children less than 8 years of age were found with otitis media. Gram positive bacteria were detected in 41.3% and gram negative in 55.6% and candida albicans in 3.2% out of total 126 bacterial cultures. Out of gram negative cultures, pseudomonas aeruginosa was found in 41.4%, proteus mirabilus in 44.3% and E.coli in 14.3% specimens. Conclusion: Gram negative bacteria are common cause of chronic suppurative otitis media in our region, mostly affecting young children. There is variable antibiotic sensitivity pattern depending on cultural, climate changes and previously taken antibiotics.

scholarly journals A cross sectional study on the bacteriologic pattern of chronic otitis media and its antibiotic sensitivity

2020 ◽  
Vol 6 (10) ◽  
pp. 1768
Author(s):  
Ramya Shree C. ◽  
Prabakaran S. ◽  
Rajasekaran S. ◽  
Priya K. ◽  
Namasivaya Navin R. B.
Keyword(s):  
Antibiotic Therapy ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Mastoid Cavity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Intracranial Complications ◽  
Culture And Sensitivity

<p><strong>Background:</strong> Chronic otitis media is the commonest middle ear and mastoid cavity disease, which has the tendency of causing morbidity to the patients ranging from deafness to intracranial complications. Hence this study was done to identify the local bacteriological pattern and its antibiotic sensitivity for treating them with appropriate antibiotic therapy.<strong></strong></p><p><strong>Methods: </strong>This cross-sectional study was done retrospectively with reports of culture and sensitivity of chronic otitis media from microbiology department. The sample was sent from the department of otorhinolaryngology in Chettinad hospital and research institute, Chennai, during the period from January 2018 to January 2020.<strong></strong></p><p><strong>Results: </strong>On assessing about 188 reports, 17 patients had no growth of organism. The commonest organism isolated was <em>Pseudomonas</em> species (33.0%) which was sensitive to imipenem (96.8%), followed by <em>Staphylococcus</em> (28.7%) which was sensitive to linezolid and teicoplanin (98.1%).<strong></strong></p><p><strong>Conclusions: </strong>The study concludes imipenem for <em>Pseudomonas</em> species and linezolid/teicoplanin for <em>Staphylococcus</em>. The appropriate and adequate antibiotic therapy is always recommended for chronic otitis media to avoid complications.<strong></strong></p>

A Comparative Cross-Sectional Study to compare the Isolated Organism and their Antibiotic Sensitivity Pattern Between Community-Acquired Pneumonia (CAP) and Ventilator-Associated Pneumonia (VAP) in Intensive Care Unit (ICU).

2021 ◽  
Vol 11 (Number 2) ◽  
pp. 26-34
Author(s):  
Nahian Ahmed Chowdhury ◽  
Dipak Kumar Mitra ◽  
Afrin Ahmed Clara ◽  
Md. Suhail Alam ◽  
MD. Zahed Hossain
Keyword(s):  
Medical Information ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Community Acquired Pneumonia ◽  
Ventilator Associated Pneumonia ◽  
Sectional Study ◽  
Cross Sectional ◽  
Mechanically Ventilated ◽  
Sensitivity Pattern ◽  
Staphylococcus Spp

Background: The moment most common cause of in-hospital infection is pneumonia. Pneumonia is prevalent within the ICU (Intensive Care Unit) setting and can be deadly. The Incidence of pneumonia is approximately 17% in the therapeutic ICU2 but can be 6 to 20 times increased in mechanically ventilated patients. The duration of hospital stay and expenditure are both expanded in patients who develop ventilator-associated pneumonia. This study aims to identify the causative microorganism responsible for CAP (Community-Acquired Pneumonia) and VAP (Ventilator-Associated Pneumonia) and their antibiotic sensitivity pattern. Methods: This was a comparative cross-sectional study that was carried out at two ICU in Sylhet city. The data was collected from the patient's medical information, the patient's file, and the hospital information system. Culture and sensitivity (C/S) were collected from the electronic medical information system (MIS). All data from January 2019 to December 2020, including patient's information, course of the disease (in terms of death or recovery-if available), clinical features, and investigation reports, was transferred to an electronic data collection sheet (Microsoft Excel). After completion of all data collection, analysis was conducted through a spreadsheet. Comparison between two disease groups was made by independent t-test. Within the group, the analysis was done by the Chi-Square test. Results: In this thesis study, it was found that the most common organism responsible for CAP was Streptococcus spp. (34.70%) and is sensitive to Meropenem (92.21%), Imipenem (88.16%), Amikacin (70.67%), Piperacillin (70.91%), Moxifloxacin (70.96%), Levofloxacin (67.95%), Amoxiclav (67.92%), and Ceftriaxone(63.95%). The most common causative organism responsible for VAP was Staphylococcus spp. (36.51%) and it was sensitive to Imipenem (100%), Moxifloxacin (100%), Meropenem (94.73%), Amikacin (85.71%), Ceftriaxone (60%), Amoxiclav (66.66%), Levofloxacin (57.14%), and Cefuroxime (50%). Conclusion: Pneumonia is still one of the most common reasons for hospitalization, particularly for those admitted to ICU. It has been observed in several studies that the majority of the cases are communityacquired pneumonia. Many mechanically ventilated patients often develop VAP, which is fatal if timely diagnosis and appropriate antibiotics administration are not made. Streptococcus spp. was the most common organism responsible for CAP, and Staphylococcus spp. mainly was responsible for VAP.

scholarly journals Antibiotic Sensitivity Pattern of Bacterial Isolates in Patients with Chronic Rhinosinusitis in Kaduna, Nigeria

2018 ◽  
Vol 23 (02) ◽  
pp. 152-156
Author(s):  
Emmanuel Musa ◽  
Aliyu Kodiya ◽  
Abdullahi Kirfi ◽  
Onyekwere Nwaorgu
Keyword(s):  
Chronic Rhinosinusitis ◽  
Anaerobic Bacteria ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Bacterial Isolates ◽  
Statistical Parameters ◽  
Cross Sectional ◽  
Sensitivity Pattern ◽  
Sensitivity Tests ◽  
Aerobic And Anaerobic

Introduction A common practice in the management of patients with chronic rhinosinusitis (CRS), the empirical use of antibiotics may contribute to treatment failure and to the development of antimicrobial resistance. Objective To determine the antibiotic sensitivity pattern of aerobic and anaerobic bacteria associated with CRS. Methods This was a prospective cross-sectional study in which endoscopically guided middle meatal swabs (IBM Spss, version 16.0, Chicago, IL, USA) were aseptically taken from patients diagnosed with CRS after obtaining informed consent and ethical clearance. The samples were sent to the laboratory for qualitative and semiquantitative analysis via gram stain, aerobic, anaerobic cultures and antibacterial sensitivity tests. The collected data was analyzed using SPSS for Windows, version 16 (SPSS Inc, Chicago, IL, USA). Simple statistical parameters and paired sample t-test were used, as appropriate. Results There were 74 (56.92%) bacterial growths, out of which 55 (74.32%) were aerobic and 19 (25.68%) were anaerobic isolates, from a total of 130 patients. About 13 (17.5%–18%) of these bacterial growths yielded a mixed growth of aerobic and anaerobic isolates. The most common bacterial isolates were 26 (35.14%) Staphylococcus aureus, Haemophilus influenzae 9 (12.16%), Streptococcus viridians 8 (10.81%), and Streptococcus pneumoniae 5 (6.76%). Augmentin, ciprofloxacin, and Peflacine were found to be most effective, followed by levofloxacin, Rocephin, erythromycin and Zinat in that order. Conclusion Augmentin, ciprofloxacin and Peflacine have a sensitivity of 100%, while most of the organisms show resistance to Ampiclox, amoxicillin, and Septrin.

scholarly journals Improvement of Tinnitus following Tympanoplasty and Tympanomastoidectomy Surgeries in Patients with Chronic Otitis Media

2016 ◽  
Vol 5 (2) ◽  
pp. 63-69
Author(s):  
Masoumeh Saeedi ◽  
Mohammad Hossein Khosravi
Keyword(s):  
Hearing Loss ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Cross Sectional Study ◽  
Common Symptom ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Tinnitus Severity ◽  
Spss Software

Background: After otorrhea and hearing loss, Tinnitus is the most common symptom in pa­tients with chronic otitis media (COM). The aim of this study was to evaluate the improvement of tinnitus in COM patients after tympanoplasty and tympanomastoidectomy surgeries. Mate­rials and Methods: This cross-sectional study was conducted on COM patients suffering from Tinnitus referred to Baqiyatallah hospital, Tehran, Iran undergoing tympanoplasty or tympano­mastoidectomy surgeries between March 2013 and August 2014. Tinnitus Handicap Inventory (THI) and Visual Analogue Scale (VAS) questionnaires were filled before and two months after surgery by each patient, and considered subjects were compared with each other. Audiometry test was taken from each patient before and two months after surgery. Audiometry results as well as Air-Bone gap were measured and evaluated prior and after surgery. Data were analyzed using SPSS software by ANOVA, sample t-test and Chi-square tests. Results: Eventually, 26 male and 24 female patients with a mean age of 38.62±11.88 years were enrolled. Air conduc­tion at all frequencies was 49.99±17.37 before and 36.98±22.06 after surgery (P<0.001). Sever­ity of tinnitus was 62.92±30.54 before and 30.54±20.08 after surgery based on THI (P<0.001). Also, it was 7.46±1.66 before and 3.5±2.06 after surgery based on VAS evaluations (P<0.001). Tinnitus severity reduction was significantly associated with the improvement of hearing loss and decrement of air-Bone gap (P<0.001). Tinnitus symptoms such as loudness, annoyance, impact on life and perception of Tinnitus significantly reduced after surgery. Moreover, Tym­panomastoidectomy was more effective on the improvement of Tinnitus in comparison with Tympanoplasty (P=0.019).Conclusion: It seems that, both tympanomastoidectomy and tympa­noplasty surgeries are effective on the improvement of tinnitus in patients with COM; however, Tympanomastoidectom surgery was shown to be more effective.[GMJ.2016;5(2):63-69]

scholarly journals Study of Antibiotic Sensitivity of Aural Swab and Aetiological Factors of Chronic Otitis Media-Active Mucosal Type

2021 ◽  
Vol 27 (2) ◽  
pp. 111-116
Author(s):  
Md Nesar Uddin ◽  
Mohammed Sirazul Islam ◽  
Mohammad Delwar Hossen ◽  
Mohammed Iftekharul Alam ◽  
Mohammad Kamal Hossain
Keyword(s):  
Otitis Media ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Military Hospital ◽  
Cross Sectional ◽  
Data Collection Sheet ◽  
One Year ◽  
Head Neck ◽  
Middle Ear Cleft

Background: Chronic otitis media (COM) refers to chronic inflammation of mucoperiosteal lining of middle ear cleft resulting in aural discharge and deafness. The objective of this study is to evaluate the antibiotic sensitivity and aetiological factors of COM. Methods: This cross-sectional study was conducted from July 2017 to June 2018 for duration of one year among the patients who attended with COM- active mucosal disease at Department of ENT & Head Neck Surgry, Combined Military Hospital (CMH) Chattogram. Total 50 cases were isolated and among them 5 cases had been suffering from bilateral COM. Aural swab was taken from 55 ears and a predesigned data collection sheet was duly filled up with the information of socioeconomic status of the patient. The laboratory records of every case was systematically organized. The data were analyzed with simple manual analysis using percentage and frequency. Results: About 24% patients were in 31-40 years age group. Out of 50 patients 62% were male. 44% patient lived in barrack. Ear cleaning habit shows, 32% has got the cleaning habit with cloth and stick. Out of 50 patients 5 had bilateral COM. So out of 55 ears, Culture & sensitivity test viewed that Pseudomonas aeruginosa was the most predominant organism - 41.8% followed by S. aureus- 30.9% Antibiotic sensitivity profile shows, 80% cases showing sensitivity to Amikacin then gentamycin-73.3% Resistant 5 cases showed 100% sensitivity to Tazobactum. Again out of 19 cases of Gram positive organism 78.9% were sensitive to Amoxyclav. 3 resistant cases showed 100% sensitivity to Meropenem. Conclusion: By studying this topic we hope to able to make an idea about the aetiological and predisposing factors and antibiotic sensitivity of COM-active mucosal variety. Bangladesh J Otorhinolaryngol 2021; 27(2): 111-116

EVALUATION OF ANTIBIOTIC SENSITIVITY PATTERN IN CHRONIC OTITIS MEDIA

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Sadhana Joshi ◽  
Gaurav Parashar
Keyword(s):  
Otitis Media ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
High Sensitivity ◽  
Mastoid Cavity ◽  
Cross Sectional ◽  
Sensitivity Pattern ◽  
Antibiotic Susceptibility Test ◽  
Amoxicillin Clavulanic Acid ◽  
Sectional Analysis

Background: Chronic otitis media (COM) is defined as chronic inflammation of middle ear and mastoid cavity that may present with recurrent ear discharges or otorrhoea through a tympanic perforation. Methods: A prospective cross sectional analysis was performed using antibiotic susceptibility test. Results: Antibiotic resistance was seen in case of the commonly used antibiotics like ampicillin, amoxicillin, Amoxicillin+Clavulanic acid. Cephalosporins were less commonly used antibiotics and showed resistance in 40.00% cases. Cotrimoxazole showed about 50.00% resistant cases. The less commonly used antibiotic was vancomycin however, showed high sensitivity (100%) followed by Linezolid (92.00%). Conclusion: Atibiotic sensitivity has been changing over time with high levels of resistance to commonly used antibiotics. Keywords: Antibiotic sensitivity, Chronic otitis media, Ear discharge

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