scholarly journals Study of Antibiotic Sensitivity of Aural Swab and Aetiological Factors of Chronic Otitis Media-Active Mucosal Type

2021 ◽  
Vol 27 (2) ◽  
pp. 111-116
Author(s):  
Md Nesar Uddin ◽  
Mohammed Sirazul Islam ◽  
Mohammad Delwar Hossen ◽  
Mohammed Iftekharul Alam ◽  
Mohammad Kamal Hossain
Keyword(s):  
Otitis Media ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Military Hospital ◽  
Cross Sectional ◽  
Data Collection Sheet ◽  
One Year ◽  
Head Neck ◽  
Middle Ear Cleft

Background: Chronic otitis media (COM) refers to chronic inflammation of mucoperiosteal lining of middle ear cleft resulting in aural discharge and deafness. The objective of this study is to evaluate the antibiotic sensitivity and aetiological factors of COM. Methods: This cross-sectional study was conducted from July 2017 to June 2018 for duration of one year among the patients who attended with COM- active mucosal disease at Department of ENT & Head Neck Surgry, Combined Military Hospital (CMH) Chattogram. Total 50 cases were isolated and among them 5 cases had been suffering from bilateral COM. Aural swab was taken from 55 ears and a predesigned data collection sheet was duly filled up with the information of socioeconomic status of the patient. The laboratory records of every case was systematically organized. The data were analyzed with simple manual analysis using percentage and frequency. Results: About 24% patients were in 31-40 years age group. Out of 50 patients 62% were male. 44% patient lived in barrack. Ear cleaning habit shows, 32% has got the cleaning habit with cloth and stick. Out of 50 patients 5 had bilateral COM. So out of 55 ears, Culture & sensitivity test viewed that Pseudomonas aeruginosa was the most predominant organism - 41.8% followed by S. aureus- 30.9% Antibiotic sensitivity profile shows, 80% cases showing sensitivity to Amikacin then gentamycin-73.3% Resistant 5 cases showed 100% sensitivity to Tazobactum. Again out of 19 cases of Gram positive organism 78.9% were sensitive to Amoxyclav. 3 resistant cases showed 100% sensitivity to Meropenem. Conclusion: By studying this topic we hope to able to make an idea about the aetiological and predisposing factors and antibiotic sensitivity of COM-active mucosal variety. Bangladesh J Otorhinolaryngol 2021; 27(2): 111-116

Bacteriology and antibiotic sensitivity pattern of ear discharge in patients with chronic otitis media; A cross sectional study conducted in tertiary care hospital of Peshawar.

2021 ◽  
Vol 28 (05) ◽  
pp. 671-676
Author(s):  
Mubassir Ullah ◽  
Muhammad Saleh Faisal ◽  
Ali Zaki ◽  
Azam Khan ◽  
Mamoor Khan ◽  
...  
Keyword(s):  
Otitis Media ◽  
Proteus Mirabilis ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Bacterial Isolates ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sensitivity Pattern ◽  
Klebsiella Spp

Objective: To determine the frequency of common bacteria and antibiotic sensitivity pattern of ear discharge in patients with chronic otitis media. Study Design: Descriptive Cross Sectional study. Setting: Department of ENT, Northwest General Hospital & Research Centre, Peshawar. Period: February to September 2019. Material & Methods: A total of 196 patients of both gender and age between 13 to 60 years with clinical diagnosis of active chronic otitis media were recruited through consecutive sampling technique. After detailed history and relevant examination, demographic data was recorded and pus specimens were collected from the infected ear on cotton swabs. They were sent to pathology laboratory of hospital for culture of common bacteria (E.coli, Pseudomonas aueroginosa, Proteus mirabilis, Staphylococcus aureus and Klebsiella spp) and their respective antibiotic sensitivity (Co-trimoxazole, Co-Amoxiclav, Ciprofloxacin, Ampicillin, Imipenem, Ceftriaxone and Cefixime). Results: Bacterial isolates were analyzed as 48% Staph aureus, 28% Pseudomonas, 12% Proteus mirabilis, 8% E. coli and 4% Klebsiella spp. Imipenem was sensitive to 94%, ceftriaxone 84%, ciprofloxacin 80%, co-trimoxazole 66%, ampicillin 63%, cefixime 45% and co-amoxiclav against 43% of total bacterial isolates. Conclusion: The common causative organism for active chronic otitis media was Staph aureus followed by Pseudomonas. Imipenem was the most sensitive antibiotic against majority of bacterial isolates followed by ceftriaxone and ciprofloxacin.

scholarly journals A cross sectional study on the bacteriologic pattern of chronic otitis media and its antibiotic sensitivity

2020 ◽  
Vol 6 (10) ◽  
pp. 1768
Author(s):  
Ramya Shree C. ◽  
Prabakaran S. ◽  
Rajasekaran S. ◽  
Priya K. ◽  
Namasivaya Navin R. B.
Keyword(s):  
Antibiotic Therapy ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
Cross Sectional Study ◽  
Mastoid Cavity ◽  
Sectional Study ◽  
Cross Sectional ◽  
Intracranial Complications ◽  
Culture And Sensitivity

<p><strong>Background:</strong> Chronic otitis media is the commonest middle ear and mastoid cavity disease, which has the tendency of causing morbidity to the patients ranging from deafness to intracranial complications. Hence this study was done to identify the local bacteriological pattern and its antibiotic sensitivity for treating them with appropriate antibiotic therapy.<strong></strong></p><p><strong>Methods: </strong>This cross-sectional study was done retrospectively with reports of culture and sensitivity of chronic otitis media from microbiology department. The sample was sent from the department of otorhinolaryngology in Chettinad hospital and research institute, Chennai, during the period from January 2018 to January 2020.<strong></strong></p><p><strong>Results: </strong>On assessing about 188 reports, 17 patients had no growth of organism. The commonest organism isolated was <em>Pseudomonas</em> species (33.0%) which was sensitive to imipenem (96.8%), followed by <em>Staphylococcus</em> (28.7%) which was sensitive to linezolid and teicoplanin (98.1%).<strong></strong></p><p><strong>Conclusions: </strong>The study concludes imipenem for <em>Pseudomonas</em> species and linezolid/teicoplanin for <em>Staphylococcus</em>. The appropriate and adequate antibiotic therapy is always recommended for chronic otitis media to avoid complications.<strong></strong></p>

scholarly journals Evaluation of hearing status after type I tympanoplasty

2020 ◽  
Vol 24 (1) ◽  
pp. 50-55
Author(s):  
Mashuque Mahamud ◽  
Mani Lal Aich ◽  
Abdullah Al Mamun ◽  
Rafiul Alam
Keyword(s):  
Otitis Media ◽  
Chronic Otitis Media ◽  
Neck Surgery ◽  
Cross Sectional Study ◽  
Type I ◽  
Cross Sectional ◽  
Female Ratio ◽  
The Mean ◽  
Type I Tympanoplasty ◽  
Air Conduction

Objective: To evaluate hearing outcome after type I tympanoplasty in inactive mucous type of chronic otitis media. Methods: It was a cross-sectional study conducted in the department of Otolaryngology & Head Neck Surgery, Sir Salimullah Medical College and Mitford Hospital, Dhaka, from July 2014 to June 2016. 50 cases were selected by matching inclusion and exclusion criteria. Paired t-test and Z test was used to analyze the variables. P values <0.05 was considered as statistically significant. Results: The mean age was found 28.5 years with range from 15 to 41 years and male female ratio was 1.3:1. All patients had intermittent otorrhoea and varying degree of hearing loss. The mean air conduction threshold was 40.2 dB preoperatively and 27.1 dB post-operatively. Air-bone gap was found 26.9 dB in preoperative and 16.1 dB in post-operative group. The differences were statistically significant between preoperative and post-operative group. Thus mean improvement of air conduction threshold was 13.1 dB and air-bone gap was 10.8 dB. Two third (66.%) patients improved <15 db air conduction thresholds and 17(34%) improved ≥15 db air conduction thresholds. Using the proportion of patients with a postoperative hearing within 40 dB as the criterion, this study showed 46(92%) patients achieving this and 40(80%) patients achieving AB gap within 20 db postoperatively. Conclusion: Improvement of air conduction threshold and AB gap after type I tympanoplasty was statistically significant. Thus from this study it can be concluded that type I tympanoplasty is an effective technique for hearing improvement in inactive mucous type of chronic otitis media. Bangladesh J Otorhinolaryngol; April 2018; 24(1): 50-55

scholarly journals Improvement of Tinnitus following Tympanoplasty and Tympanomastoidectomy Surgeries in Patients with Chronic Otitis Media

2016 ◽  
Vol 5 (2) ◽  
pp. 63-69
Author(s):  
Masoumeh Saeedi ◽  
Mohammad Hossein Khosravi
Keyword(s):  
Hearing Loss ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Cross Sectional Study ◽  
Common Symptom ◽  
Sectional Study ◽  
Chi Square ◽  
Cross Sectional ◽  
Tinnitus Severity ◽  
Spss Software

Background: After otorrhea and hearing loss, Tinnitus is the most common symptom in pa­tients with chronic otitis media (COM). The aim of this study was to evaluate the improvement of tinnitus in COM patients after tympanoplasty and tympanomastoidectomy surgeries. Mate­rials and Methods: This cross-sectional study was conducted on COM patients suffering from Tinnitus referred to Baqiyatallah hospital, Tehran, Iran undergoing tympanoplasty or tympano­mastoidectomy surgeries between March 2013 and August 2014. Tinnitus Handicap Inventory (THI) and Visual Analogue Scale (VAS) questionnaires were filled before and two months after surgery by each patient, and considered subjects were compared with each other. Audiometry test was taken from each patient before and two months after surgery. Audiometry results as well as Air-Bone gap were measured and evaluated prior and after surgery. Data were analyzed using SPSS software by ANOVA, sample t-test and Chi-square tests. Results: Eventually, 26 male and 24 female patients with a mean age of 38.62±11.88 years were enrolled. Air conduc­tion at all frequencies was 49.99±17.37 before and 36.98±22.06 after surgery (P<0.001). Sever­ity of tinnitus was 62.92±30.54 before and 30.54±20.08 after surgery based on THI (P<0.001). Also, it was 7.46±1.66 before and 3.5±2.06 after surgery based on VAS evaluations (P<0.001). Tinnitus severity reduction was significantly associated with the improvement of hearing loss and decrement of air-Bone gap (P<0.001). Tinnitus symptoms such as loudness, annoyance, impact on life and perception of Tinnitus significantly reduced after surgery. Moreover, Tym­panomastoidectomy was more effective on the improvement of Tinnitus in comparison with Tympanoplasty (P=0.019).Conclusion: It seems that, both tympanomastoidectomy and tympa­noplasty surgeries are effective on the improvement of tinnitus in patients with COM; however, Tympanomastoidectom surgery was shown to be more effective.[GMJ.2016;5(2):63-69]

Mothers’ Knowledge about Diaper Rash and Preventive Measures in Bangladesh

2021 ◽  
Vol 36 (1) ◽  
pp. 39-45
Author(s):  
Zahir Sadique ◽  
Nurunnahar Fatema Begum ◽  
Md Ferdousur Rahman Sarker ◽  
Md Nazmul Islam Bhuyian ◽  
Md Kamruzzaman
Keyword(s):  
Preventive Measures ◽  
Cross Sectional Study ◽  
Military Hospital ◽  
Cross Sectional ◽  
Outpatient Visits ◽  
Life Threatening ◽  
Knowledge And Practice ◽  
One Year ◽  
Disposable Diapers ◽  
Perineal Care

Background: Use of disposable diapers by parents for their children has grown in last few decades. Although, most of the time diaper rash is not life threatening, it is a concern for the parents, and uncomfortable and painful for children Objectives: To measure the knowledge and practice of mothers when diapering and administering perineal care to infants wearing disposable diapers and factors that can influence the frequency of the occurrence of diaper rash in children between 0-12 months in Bangladesh. Methods: This cross-sectional study was conducted during the outpatient visits of mothers and their infants at the Combined Military Hospital located in Cumilla, Bangladesh between 01 February 2015 and 31 July 2015 with their infants. A structured, self-completed, closed-ended questionnaire was provided to 110 mothers who came to visit the Pediatric outdoors. Results: Thirty-seven (33.64%) infants aged one or under were reported to have experienced diaper rash during or prior to enrolment in the study. Study analysis showed that the risk of diaper rash was significantly higher in babies who used only 1-2 diapers/day than for babies who used more than 4 diapers/day (40.0% vs 21.43%). Infants whose mothers had knowledge of the causes and preventions of diaper rash and/or who received information about the importance of the proper cleaning of the diaper area during diaper changes suffered fewer incidents of diaper rash than those whose mothers did not (24% vs 36.48%). The causes of diaper rash were described by 48.65% mothers as heat followed by 27.03% mothers by frequent stool/urine. Conclusion: Frequently changing disposable diapers and cleaning the diaper area thoroughly can reduce cases of diaper rash dramatically in children less than one year old. The knowledge of mothers regarding diaper rash is an important factor in reducing diaper rash in their children. DS (Child) H J 2020; 36(1) : 39-45

scholarly journals Role of Growth factors (HB-EGF, VEGF- A) and Immunotolerance Mediators (TNF-alphaIFN-gamma,PD-L1 and IL-10) in Acute and Chronic Otitis Media

2020 ◽  
Author(s):  
SELVAKUMARI MATHIYALAGAN ◽  
Anand D Karthikeyan ◽  
Ramakrishnan R ◽  
Melvin George
Keyword(s):  
Otitis Media ◽  
Chronic Otitis Media ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Luminex Assay ◽  
Tympanic Membrane Perforations ◽  
Immune Mediated ◽  
Disease Condition ◽  
Severity Of The Disease

Abstract Objectives: There is an increasing evidence of immune mediated mechanism in the etiopathogenesis of Otitis Media prime middle ear inflammation prime. The aim of the present study was to determine the expression of important circulatory regulators of immunotolerance as biomarkers. Materials and Methods In this cross sectional study, a total of 44 OM patients and 37 controls were included. Blood plasma level of HB-EGF, IL-10, TNF-alpha, IFN-gamma, PD-L1 and VEGF-A were quantified using Human Magnetic Luminex assay. Results The study showed statistical significant differences in the levels of VEGF-A between OM patients with and without tympanic membrane perforations (p<0.05). Moreover, we found comparatively higher level of PD-L1 in OM patients than controls. However, the level of growth factor HB-EGF, is significantly higher in controls than the cases (p<0.05). There was also a correlation between the levels of HB-EGF and VEGF-A and the severity of the disease condition. Conclusions Role of inflammatory mediators and cytokines like PD-L1, IFNgamma, TNFalpha and IL-10in OM patients as a biomarkers are very minimal. VEFG-A have a significant role in the pathogenesis of OM.Further studies are required for better understanding of the role of these immunosuppressive mediators in the eitopathogenesis of OM.

scholarly journals Audiological evaluation in children and adolescents with turner syndrome by otoacustic emissions

2020 ◽  
Vol 12 (5) ◽  
pp. 156-159
Author(s):  
Bettina Carvalho
Keyword(s):  
Turner Syndrome ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Tertiary Hospital ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
True Nature ◽  
Distortion Product ◽  
History Of ◽  
Study Methodology

Turner syndrome (TS) is characterized by short stature and hypergonadotrophic hypogonadism, associated with typical somatic features. Although hearing loss (HL) was not reported in Henry Turner first description of the disease, it has been brought to attention in the last decades in many studies. But the true nature of this problem is still unknown due to inconsistent data resulting from different study methodology. The purpose of this study is to evaluate hearing of TS girls using Audiometry and Otoacustic emissions, both Distortion product (DPOAEs) and Transient (TOAEs) in the outpatient clinic of a tertiary hospital and hearing complaints of these patients. Materials and Methods: prospective cross-sectional study of TS girls aging from six to 19 years old. Results: 13 patients with TS (26 ears) were evaluated. They showed in Audiometry: normal hearing in 14 ears, NSHL in three ears, conductive in seven and mixed HL in two ears (12 alterations). In the DPOAEs: 19 absent responses (73.1% of cases) in at least one frequency, and in TOAEs: 16 absent responses (61.5%). 15 absent responses in both tests (57.7%). Five patients had history of chronic otitis media. Conclusion: The presence of auditory alterations in TS patients assessed by OAE was high, with presence of history of chronic otitis media and their complications. Only one patient had hearing complaints. These findings should bring to attention HL in these patients, even without complaints.

EVALUATION OF ANTIBIOTIC SENSITIVITY PATTERN IN CHRONIC OTITIS MEDIA

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Sadhana Joshi ◽  
Gaurav Parashar
Keyword(s):  
Otitis Media ◽  
Chronic Otitis Media ◽  
Antibiotic Sensitivity ◽  
High Sensitivity ◽  
Mastoid Cavity ◽  
Cross Sectional ◽  
Sensitivity Pattern ◽  
Antibiotic Susceptibility Test ◽  
Amoxicillin Clavulanic Acid ◽  
Sectional Analysis

Background: Chronic otitis media (COM) is defined as chronic inflammation of middle ear and mastoid cavity that may present with recurrent ear discharges or otorrhoea through a tympanic perforation. Methods: A prospective cross sectional analysis was performed using antibiotic susceptibility test. Results: Antibiotic resistance was seen in case of the commonly used antibiotics like ampicillin, amoxicillin, Amoxicillin+Clavulanic acid. Cephalosporins were less commonly used antibiotics and showed resistance in 40.00% cases. Cotrimoxazole showed about 50.00% resistant cases. The less commonly used antibiotic was vancomycin however, showed high sensitivity (100%) followed by Linezolid (92.00%). Conclusion: Atibiotic sensitivity has been changing over time with high levels of resistance to commonly used antibiotics. Keywords: Antibiotic sensitivity, Chronic otitis media, Ear discharge

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