scholarly journals Outcome of patients treated with N-Butyl-2-cyanoacrylate in gastric variceal bleeding.

2021 ◽  
Vol 28 (10) ◽  
pp. 1463-1469
Author(s):  
Ameet Jesrani ◽  
Riaz Hussain Awan ◽  
Latif Aziz Memon ◽  
Seema Nayab
Keyword(s):  
Retrospective Study ◽  
Mortality Rate ◽  
Hospital Stay ◽  
Injection Technique ◽  
Endoscopic Injection ◽  
Variceal Bleed ◽  
Pugh Class ◽  
The Mean ◽  
Study Setting ◽  
Overall Mortality

Objective: Aim of study was to determine outcomes of patients treated with N-butyl-2-cyanoacrylate. Study Design: Retrospective study. Setting: Department of Gastroenterology at Liaquat University of Medical and Health Sciences, Jamshoro. Period: December 2019 to March 2020. Material & Methods: A Retrospective study was conducted between by viewing medical records and endoscopy reports. Total 31 patients were enrolled with gastric variceal bleed that underwent endoscopic injection of N-butyl-2-cyanoacrylate we examined the mortality rate, hemostasis, Hospital stay, need of blood transfusion, and effectiveness of procedure. Results: A Total of 31 patients, out of which 18 (58.1 %) were male; the mean age was 55.23±8.778 years. Of these patients 23 (74.2 %), had concomitant esophageal varices, Child-Pugh class-A, B, C were seen in 4, 20 & 7 patients (12.9, 64.5 % & 22.6) respectively. Average duration of hospital stay was 5 to 8 days in 22 cases (71.0 %). Less than 3 pints of PRBC were transfused in 17 cases (54.8 %). Hemostasis was achieved in 27 patients (87%). Overall mortality rate was 3 out of 31(9.7%). one patient was referred for TIPSS. No complications from cyanoacrylate injection were observed. Conclusion: Standardized injection technique and regimen ensures the success and safety of N-butyl-2-cyanoacrylate injection for the treatment of gastric fundal varices in experienced hands.

scholarly journals Severity, Treatment, and Outcome of Acute Pancreatitis in Thailand: The First Comprehensive Review Using Revised Atlanta Classification

2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Supot Pongprasobchai ◽  
Peeradon Vibhatavata ◽  
Piyaporn Apisarnthanarak
Keyword(s):  
Acute Pancreatitis ◽  
Retrospective Study ◽  
Mortality Rate ◽  
Necrotizing Pancreatitis ◽  
Median Length ◽  
Comprehensive Review ◽  
Ringer’S Lactate ◽  
The Mean ◽  
Lactate Solution ◽  
Overall Mortality

Background.Severity and outcome of acute pancreatitis (AP) in Thailand are unknown.Methods. A retrospective study of 250 patients with AP during 2011–2014 was performed. Severity, treatment, and outcome were evaluated. Severity was classified by revised Atlanta classification.Results. The mean age was 58 years and 56% were men. Etiologies were gallstones (45%), alcohol (16%), postendoscopic retrograde cholangiopancreatography (14%), and idiopathic (15%). Overall, 72%, 16%, and 12% of patients had mild, moderately severe, and severe AP, respectively. Two major types of initial intravenous fluid were normal saline (64%) and Ringer’s lactate solution (RLS, 28%). Enteral nutrition was given in 77% of patients with severe AP, median duration 48 hours, and via a nasogastric tube in 67% of patients. Necrotizing pancreatitis (NP) developed in 7% of patients, and 29% of them developed infection (median 17 days). The median length of stay was 6, 9, and 13 days, and the mortality rate was 1%, 3%, and 42% in mild, moderately severe, and severe AP, respectively. The overall mortality rate was 6%.Conclusion. The severity of AP in Thailand was mild, moderately severe, and severe in 72%, 16%, and 12% of patients, respectively. NP was not prevalent. Mortality was high in severe AP. Most treatments complied with standard guidelines except the underuse of RLS.

Lamb mortality in a flock of East African Blackheaded sheep

1966 ◽  
Vol 66 (1) ◽  
pp. 97-100 ◽  
Author(s):  
J. C. M. Trail ◽  
G. D. Sacker
Keyword(s):  
Birth Weight ◽  
Mortality Rate ◽  
Mortality Rates ◽  
Dry Season ◽  
East African ◽  
Male And Female ◽  
The Mean ◽  
Overall Mortality

1. The effects of birth weight, sex, twinning, parity of dam and dry season on mortality rates of lambs were studied between birth and weaning at 20 weeks in a flock of East African Blackheaded sheep.2. The mean birth weights of non-surviving lambs were lower than those of surviving lambs. Singles from gimmers and twins from ewes were 0.5 and 1.0 lb., respectively, lighter at birth, and had higher mortality rates than singles from ewes. The overall mortality rate of singles from ewes was 16%, singles from gimmers 20% and twins from ewes 28%. Male and female lambs born alive had similar mortality rates (18%).

Prevalence, Demographic Patterns, and Outcome of Childhood Malignancies in a Tertiary Hospital in Nigeria: A 15-Year Retrospective Study

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S89-S90
Author(s):  
Oluwakemi Otokiti ◽  
Edamisan Temiye
Keyword(s):  
Health Care ◽  
Retrospective Study ◽  
Mortality Rate ◽  
Hematological Malignancies ◽  
Financial Burden ◽  
Age At Diagnosis ◽  
Childhood Cancers ◽  
Childhood Malignancies ◽  
Wilm’S Tumor ◽  
Overall Mortality

Abstract Objectives Childhood cancers are increasingly recognized as a cause of childhood morbidity and mortality following improvement in immunization programs and sanitation against communicable diseases. With improvement in health care, better survival outcomes have been reported in childhood cancers worldwide. However, mortality associated with childhood cancers remains high in developing countries. This study aims to determine the prevalence, demographic characteristics, and outcome of childhood cancers seen in Lagos University Teaching Hospital, Lagos, Nigeria. Methods A retrospective study analyzed 749 cases of childhood malignancies between 2003 and 2017. Data on gender, age at diagnosis, diagnosis, and outcome were extracted using a data extraction proforma. Data were analyzed using SPSS v23. P value of .05 was considered statistically significant. Results Median age at diagnosis was 4.75 years with a male to female ratio of 1.3:1. Highest prevalence was noticed with hematological malignancies (41%), Wilm’s tumor (18%), retinoblastoma (13%), and soft tissue tumors (6.5%) and lowest prevalence with testicular cancers (0.3%). Apart from liver malignancy, males had a higher incidence in all malignancies. Median age at diagnosis was 12 years for nasopharyngeal carcinoma, 11 years for bone cancers, 8 years for gynecological cancers, 6 years for hematological cancers, and 0.47 years for testicular cancers. Overall mortality rate was 30%, and a significant number (53%) were lost to follow-up (discharged against medical advice, defaulted, financial burden, medical tourism). Hematological malignancies had the highest mortality rates, with Wilm’s tumor having best survival chances (lowest mortality). Conclusion Prevalence patterns mirror what was obtained in other centers (Jos, Ife, and Ibadan). A mortality rate of 30% is significant. Financial burden, religious beliefs, delay in presentation, and ignorance are major hindrances to health care and might contribute significantly to overall mortality and outcome. More needs to be done concerning childhood cancers.

scholarly journals Suicide in the elderly: an epidemiologic study

2021 ◽  
Vol 55 ◽  
Author(s):  
Mariana Cristina Lobato dos Santos ◽  
Barbara Bartuciotti Giusti ◽  
Clarissa Ayri Yamamoto ◽  
Suely Itsuko Ciosak ◽  
Regina Szylit
Keyword(s):  
Retrospective Study ◽  
Mortality Rate ◽  
General Population ◽  
Elderly Population ◽  
Epidemiologic Study ◽  
The Elderly ◽  
Cross Sectional ◽  
The Mean ◽  
Elderly Suicide ◽  
High Place

ABSTRACT Objective: To analyze the incidence and means of elderly suicide in Brazil. Method: Epidemiologic, cross-sectional, quantitative, and retrospective study. The data were obtained in a platform maintained by the Ministry of Health and analyzed. The mortality rate was calculated and means and percentages regarding the employed means of suicide were obtained. Results: In this period, 8,977 suicides took place among the population over 60 years. The highest suicide rates were concentrated in the population over 80, which presented a mean 8.4/100,000 for this period, and between 70 and 79 years, with a mean rate of 8.2/100,000. Considering the total elderly population over 60 years, this value reached 7.8/100,000, whereas in the general population this was 5.3/100,000. The values are always higher among the elderly population: the mean rate in the last five years among the elderly is 47.2% higher than the mean for the general population. The main mean of suicide was hanging (68%), followed by firearm (11%), self-intoxication (9%), falling from a high place (5%), and undefined or undetermined means (6%). Conclusion: Epidemiologic analyses bring visibility to the dyad aging and suicide, corroborating the pertinence of this theme.

scholarly journals Outcome improvement in cerebral ventriculitis after ventricular irrigation: a prospective controlled study

2020 ◽  
Vol 26 (6) ◽  
pp. 682-690
Author(s):  
Ahmed Al Menabbawy ◽  
Ehab El Refaee ◽  
Mohamed A. R. Soliman ◽  
Mohamed A. Elborady ◽  
Mohamed A. Katri ◽  
...  
Keyword(s):  
Mortality Rate ◽  
Hospital Stay ◽  
Conventional Group ◽  
Controlled Study ◽  
Csf Shunt ◽  
Duration Of Hospital Stay ◽  
Cerebral Ventriculitis ◽  
The Mean ◽  
Prospective Controlled Study ◽  
Hospital Stay Duration

OBJECTIVECerebral ventriculitis remains one of the most challenging neurosurgical conditions, with poor outcome and a long course of treatment and duration of hospital stay. Despite the current conventional management plans, i.e., using antibiotics in addition to CSF drainage, the outcome remains unsatisfactory in some cases, with no definitive therapeutic guidelines. This study aims to compare the outcome of ventricular irrigation/lavage (endoscopic irrigation or the double-drain technique) to conventional currently accepted therapy using just drainage and antibiotics.METHODSThe authors conducted a prospective controlled study in 33 patients with cerebral ventriculitis in which most of the cases were complications of CSF shunt operations. Patients were divided into two groups. Removal of the ventricular catheter whenever present was performed in both groups. The first group was managed by ventricular lavage/irrigation, while the other group was managed using conventional therapy by inserting an external ventricular drain. Both systemic and intraventricular antibiotics were used in both groups. The outcomes were compared regarding mortality rate, modified Rankin Scale (mRS) score, and duration of hospital stay.RESULTSThe mean age of the study population was 5.98 ± 7.02 years. The mean follow-up duration was 7.6 ± 3.2 months in the conventional group and 5.7 ± 3.4 months in the lavage group. The mortality rate was 25% (4/16) in the lavage group and 52.9% (9/17) in the nonlavage group (p = 0.1). The mRS score was less than 3 (good outcome) in 68.8% (11/16) of the lavage group cases and in 23.5% (4/17) of the conventional group (p < 0.05). The mean hospital stay duration was 20.5 ± 14.2 days in the lavage group, whereas it was 39.7 ± 16.9 days in the conventional group (p < 0.05).CONCLUSIONSVentricular lavage or irrigation together with antibiotics is useful in the management of cerebral ventriculitis and associated with a better outcome and shorter hospital stay duration compared to current conventional lines of treatment.

scholarly journals Risk of invasive candidiasis with prolonged duration of ICU stay: a systematic review and meta-analysis

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e036452
Author(s):  
Zhidan Zhang ◽  
Ran Zhu ◽  
Zhenggang Luan ◽  
Xiaochun Ma
Keyword(s):  
Hospital Stay ◽  
Meta Analysis ◽  
Icu Admission ◽  
Duration Of Hospital Stay ◽  
Icu Stay ◽  
Significant Difference ◽  
The Mean ◽  
Meta Regression ◽  
Length Of Icu Stay ◽  
Overall Mortality

ObjectiveThis study aimed to evaluate the duration of intensive care unit (ICU) stay prior to onset of invasive candidiasis (IC)/candidaemia.DesignSystematic review and meta-analysis.Data sourcesPubMed, Cochrane, Embase and Web of Science databases were searched through June 2019 to identify relevant studies.Eligibility criteriaAdult patients who had been admitted to the ICU and developed an IC infection.Data extraction and synthesisThe following data were extracted from each article: length of hospital stay, length of ICU stay, duration of ICU admission prior to candidaemia onset, percentage of patients who received antibiotics and duration of their antibiotic therapy prior to candidaemia onset, and overall mortality. In addition to the traditional meta-analyses, meta-regression was performed to explore possible mediators which might have contributed to the heterogeneity.ResultsThe mean age of patients ranged from 28 to 76 years across selected studies. The pooled mean duration of ICU admission before onset of candidaemia was 12.9 days (95% CI 11.7 to 14.2). The pooled mean duration of hospital stay was 36.3±5.3 days (95% CI 25.8 to 46.7), and the pooled mean mortality rate was 49.3%±2.2% (95% CI 45.0% to 53.5%). There was no significant difference in duration of hospital stay (p=0.528) or overall mortality (p=0.111), but a significant difference was observed in the mean length of ICU stay (2.8 days, p<0.001), between patients with and without Candida albicans. Meta-regression analysis found that South American patients had longer duration of ICU admission prior to candidaemia onset than patients elsewhere, while those in Asia had the shortest duration.ConclusionsPatients with IC are associated with longer ICU stay, with the shortest duration of ICU admission prior to the candidaemia onset in Asia. This shows a more proactive strategy in the diagnosis of IC should be considered in caring for ICU patients.

scholarly journals Safety and efficacy of the Pipeline embolization device for treatment of intracranial aneurysms: a pooled analysis of 3 large studies

2017 ◽  
Vol 127 (4) ◽  
pp. 775-780 ◽  
Author(s):  
David F. Kallmes ◽  
Waleed Brinjikji ◽  
Saruhan Cekirge ◽  
David Fiorella ◽  
Ricardo A. Hanel ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Retrospective Study ◽  
Mortality Rate ◽  
Intracranial Hemorrhage ◽  
Intracranial Aneurysms ◽  
Pooled Analysis ◽  
Pipeline Embolization Device ◽  
Neurological Morbidity ◽  
The Mean

OBJECTIVEThe authors performed a pooled analysis of 3 studies—IntrePED (International Retrospective Study of the Pipeline Embolization Device), PUFS (Pipeline for Uncoilable or Failed Aneurysms Study), and ASPIRe (Aneurysm Study of Pipeline in an Observational Registry)—in order to assess angiographic outcomes and clinical safety of the Pipeline embolization device (PED).METHODSIntrePED was a retrospective study, while PUFS and ASPIRe were prospective studies. For each patient included in these studies, the authors collected baseline demographic data, aneurysm characteristics, and procedural details. The primary outcomes for this combined analysis were clinical outcomes, including neurological morbidity and mortality and major ipsilateral intracranial hemorrhage and ischemic stroke. The secondary outcomes were angiographic occlusion rates, which were available for ASPIRe and PUFS only.RESULTSA total of 1092 patients with 1221 aneurysms were included across the 3 studies. The mean aneurysm size was 12.0 ± 7.8 mm and the mean neck size was 6.6 ± 4.8 mm. The major ipsilateral ischemic stroke rate was 3.7% (40/1091). The major ipsilateral intracranial hemorrhage rate was 2.0% (22/1091). The major neurological morbidity rate was 5.7% (62/1091). The neurological mortality rate was 3.3% (36/1091). The combined major morbidity and neurological mortality rate was 7.1% (78/1091). The complete occlusion rates were 75.0% at 180 days (111/148) and 85.5% at 1 year (94/110). The overall aneurysm retreatment rate was 3.0% (33/1091) at a mean follow-up time of 10.2 ± 10.8 months.CONCLUSIONSEndovascular treatment of intracranial aneurysms with the PED is safe and effective. Angiographic occlusion rates progressed with follow-up. Rates of stroke, hemorrhage, morbidity and mortality, and retreatment were low, especially given the fact that the aneurysms treated were generally large and wide necked.

Depilatory Agents intoxication and factors contributing to its mortality: A 9-year review

2011 ◽  
Vol 30 (10) ◽  
pp. 1454-1457
Author(s):  
Esmaeil Farzaneh ◽  
Babak Mostafazadeh ◽  
Nasim Zamani ◽  
Armen Eskandari ◽  
Mohammadali Emamhadi
Keyword(s):  
Retrospective Study ◽  
Mortality Rate ◽  
Medical Records ◽  
Time Of Arrival ◽  
Emergency Ward ◽  
Western Countries ◽  
The Mean ◽  
Mean Time

Poisoning with depilatory agents is a rather uncommon entity in western countries. In this study, we describe poisoning with a corrosive arsenic-based depilatory agent (CABD) and factors related to its mortality in a poisoning center in Tehran. In a retrospective study, the medical records of all patients with CABD intoxication who attended the emergency ward of Loghman-Hakim hospital, the only poisoning center in Tehran, over a 9-year period between 2000 and 2009 were reviewed. The majority of patients were men (78.7%, n = 122 vs. women: 21.3%, n = 33). The mean age was 35.55 ± 16.68 years. Mean time of arrival to hospital was 3.63 hours (SD = 4.07). The mortality rate was 5.8% and increased significantly with higher amounts of ingestion and delay in arrival to hospital. CABD poisoning may be lethal if not treated promptly and correctly. Restriction or, if not practical, reduction of harmful components of this substance should be considered.

scholarly journals Clinical Outcomes of Pediatric Chronic Intestinal Pseudo-Obstruction

2021 ◽  
Vol 10 (11) ◽  
pp. 2376
Author(s):  
Dayoung Ko ◽  
Hee-Beom Yang ◽  
Joong Youn ◽  
Hyun-Young Kim
Keyword(s):  
Mortality Rate ◽  
Parenteral Nutrition ◽  
Clinical Outcomes ◽  
Associated Factors ◽  
Rare Condition ◽  
Onset Age ◽  
The Mean ◽  
Intestinal Pseudo Obstruction ◽  
Overall Mortality

Chronic intestinal pseudo-obstruction (CIPO) is an extremely rare condition with symptoms of recurrent intestinal obstruction without any lesions. The outcomes of pediatric CIPO and predictors for the outcomes have not yet been well established. We analyzed the clinical outcomes and associated factors for the outcomes of pediatric CIPO. We retrospectively reviewed 66 primary CIPO patients diagnosed between January 1985 and December 2017. We evaluated parenteral nutrition (PN) factors such as PN duration, PN use over 6 months, home PN, and mortality as outcomes. We selected onset age, presence of urologic symptoms, pathologic type, and involvement extent as predictors. The early-onset CIPO was found in 63.6%, and 21.2% of the patients presenting with urologic symptoms. Of the 66 patients, 47 and 11 had neuropathy and myopathy, respectively. The generalized involvement type accounted for 83.3% of the cases. At the last follow-up, 24.2% of the patients required home PN management. The mean duration of PN was 11.8 ± 21.0 months. The overall mortality rate of primary CIPO was 18.2%. PN factors were predicted by the urologic symptoms and extent of involvement. However, mortality was predicted by pathologic type. The onset age was not significantly associated with the outcomes. CIPO with urologic symptoms and generalized CIPO had poor PN outcomes. Myopathy is suggested as a predictor of mortality in children with primary CIPO.

scholarly journals Is Nasogastric Tube essential in abdominal surgeries? Randomized controlled trail.

2021 ◽  
Vol 28 (10) ◽  
pp. 1397-1400
Author(s):  
Muhammad Bilal ◽  
Viqar Aslam ◽  
Zaheeruddin ◽  
Waqas Jan
Keyword(s):  
Hospital Stay ◽  
Nasogastric Tube ◽  
P Value ◽  
Randomized Controlled ◽  
Group A ◽  
Randomized Controlled Trail ◽  
The Mean ◽  
Group B ◽  
Study Setting ◽  
Tube Study

Objective: Objective was to compare mean hospital stay in patients with abdominal surgeries with and without Nasogastric tube. Study Design: Randomized Controlled Trail study. Setting: DHQ Charsadda. Period: Jan to Nov 2018. Material & Methods: One hundred and thirty two patients who underwent abdominal surgeries according to a preset inclusion criteria were in this study. These Patients were randomly assigned using sealed opaque envelopes containing computer‐generated random numbers into with and without NG tube. Mean hospital stay was noted in both groups. Student ‘t’ test was used to compare the mean hospital stay of both groups. Results: Mean age of patients in group A was 28.50 ± 9.28 years and for group B was 30.12+_9.09 years. Mean hospital stay for group A was 5.64+_2.32days and for group B was 8.73+_3.43 days with a p-value of < 0.000. Conclusion: Patient with nasogastric tube stay longer in hospital than without tube.

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