scholarly journals Peremajaan Kawasan Pasar Kiaracondong Berkonsep Pasar Sehat

2021 ◽  
Vol 1 (1) ◽  
pp. 15-22
Author(s):  
Fahri Nazarudin ◽  
Sri Hidayati Djoeffan

Abstract. The market is an economic sector that can improve people's welfare and be used by Governments as a wheel of economy. Traditional market nowadays existence aside from the existence of modern market, Kiaracondong Market has a pontesi as a first class market, trader as much as 1058 and has easy access. However, there are problems in terms of visual, environmental and functional. To fix the problem there is a rejuvenation need to be done. The purpose of this research is to rejuvenate the traditional market area of Kiaracondong to be comfortable, safe, clean healthy and sustainable. The method used is a theoretical, normative, comparative, participatory, and description-statistical approach. By using site analysis, population, land support, space needs, building typology, building period, City rejuvenation strategy and the determination of functional elements. Thus obtained the direction of design concept based on the results of analysis that has been done in the form of land use plan, period building, circulation and parking, green open space, pedestrian path, support activities, utility networks and Recommendations. Abstrak. Pasar merupakan sektor perekonomian yang dapat meningkatkan kesejahteraan masyarakat dan digunakan oleh pemerintah sebagai roda perekonomian. Pasar tradisional saat ini keberadaannya tersisihkan adanya pasar modern, pasar kiaracondong memiliki pontesi sebagai pasar kelas satu, pedagang sebanyak 1058 dan memiliki akses yang mudah. Namun, terdapat permasalahan dari segi visual, lingkungan dan fungsional. Untuk memperbaiki permasalahan yang ada maka perlu dilakukan peremajaan. Tujuan dari penelitian ini ialah meremajakan kawasan pasar tradisional kiaracondong agar nyaman, aman, bersih sehat dan berkelanjutan. Metode yang digunakan berupa pendekatan teoritis, normatif, komparatif, partisipatif dan statistik deskripsi. Dengan menggunakan analisis tapak, kependudukan, daya dukung lahan, kebutuhan ruang, tipologi bangunan, tata masa bangunan, stategi peremajaan kota dan penentuan elemen fungsional. Sehingga diperoleh arahan konsep perancangan berdasarkan hasil analisis yang telah dilakukan berupa rencana tata guna lahan, tata masa bangunan, sirkulasi dan parkir, ruang terbuka hijau, jalur pejalan kaki, aktivitas pendukung, jaringan utilitas dan rekomendasi.

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 298
Author(s):  
Alexander Ecke ◽  
Rudolf J. Schneider

Contamination of waters with pharmaceuticals is an alarming problem as it may support the evolution of antimicrobial resistance. Therefore, fast and cost-effective analytical methods for potential on-site analysis are desired in order to control the water quality and assure the safety of its use as a source of drinking water. Antibody-based methods, such as the enzyme-linked immunosorbent assay (ELISA), can be helpful in this regard but can also have certain pitfalls in store, depending on the analyte. As shown here for the class of β-lactam antibiotics, hydrolysis of the β‑lactam ring is a key factor in the immunochemical analysis as it influences antibody recognition. With the antibody used in this study, the limit of detection (LOD) in the immunoassay could be significantly reduced by hydrolysis for the five tested penicillins, with the lowest LOD for carbenicillin (0.2 nmol/L) and the greatest impact on penicillins G and V (reduction by 85%). In addition to enhanced quantification, our strategy also provides access to information about the degree of hydrolysis in water samples as shown for the most abundant penicillin amoxicillin.


Genetics ◽  
2001 ◽  
Vol 157 (3) ◽  
pp. 1387-1395 ◽  
Author(s):  
Sudhir Kumar ◽  
Sudhindra R Gadagkar ◽  
Alan Filipski ◽  
Xun Gu

AbstractGenomic divergence between species can be quantified in terms of the number of chromosomal rearrangements that have occurred in the respective genomes following their divergence from a common ancestor. These rearrangements disrupt the structural similarity between genomes, with each rearrangement producing additional, albeit shorter, conserved segments. Here we propose a simple statistical approach on the basis of the distribution of the number of markers in contiguous sets of autosomal markers (CSAMs) to estimate the number of conserved segments. CSAM identification requires information on the relative locations of orthologous markers in one genome and only the chromosome number on which each marker resides in the other genome. We propose a simple mathematical model that can account for the effect of the nonuniformity of the breakpoints and markers on the observed distribution of the number of markers in different conserved segments. Computer simulations show that the number of CSAMs increases linearly with the number of chromosomal rearrangements under a variety of conditions. Using the CSAM approach, the estimate of the number of conserved segments between human and mouse genomes is 529 ± 84, with a mean conserved segment length of 2.8 cM. This length is <40% of that currently accepted for human and mouse genomes. This means that the mouse and human genomes have diverged at a rate of ∼1.15 rearrangements per million years. By contrast, mouse and rat are diverging at a rate of only ∼0.74 rearrangements per million years.


2020 ◽  
Author(s):  
Luis Valledor ◽  
Sara Guerrero ◽  
Lara García-Campa ◽  
Mónica Meijón

Abstract Bud maturation is a physiological process which implies a set of morphophysiological changes which lead to the transition of growth patterns from young to mature. This transition defines tree growth and architecture, and in consequence traits such as biomass production and wood quality. In Pinus pinaster, a conifer of great timber value, bud maturation is closely related to polycyclism (multiple growth periods per year). This process causes a lack of apical dominance, and consequently increased branching that reduces its timber quality and value. However, despite its importance, little is known about bud maturation. In this work, proteomics and metabolomics were employed to study apical and basal sections of young and mature buds in P. pinaster. Proteins and metabolites in samples were described and quantified using (n)UPLC-LTQ-Orbitrap. The datasets were analyzed employing an integrative statistical approach, which allowed the determination of the interactions between proteins and metabolites and the different bud sections and ages. Specific dynamics of proteins and metabolites such as HISTONE H3 and H4, RIBOSOMAL PROTEINS L15 and L12, CHAPERONIN TCP1, 14–3-3 protein gamma, gibberellins A1, A3, A8, strigolactones and ABA, involved in epigenetic regulation, proteome remodeling, hormonal signaling and abiotic stress pathways showed their potential role during bud maturation. Candidates and pathways were validated employing interaction databases and targeted transcriptomics. These results increase our understanding of the molecular processes behind bud maturation a key step towards improving timber production and natural pine forests management in a future scenario of climate change. However, further studies are necessary by using different P. pinaster populations that show contrasting wood quality and stress tolerance in order to generalize the results.


Vestnik MGSU ◽  
2015 ◽  
pp. 140-151 ◽  
Author(s):  
Aleksey Alekseevich Loktev ◽  
Daniil Alekseevich Loktev

In modern integrated monitoring systems and systems of automated control of technological processes there are several essential algorithms and procedures for obtaining primary information about an object and its behavior. The primary information is characteristics of static and moving objects: distance, speed, position in space etc. In order to obtain such information in the present work we proposed to use photos and video detectors that could provide the system with high-quality images of the object with high resolution. In the modern systems of video monitoring and automated control there are several ways of obtaining primary data on the behaviour and state of the studied objects: a multisensor approach (stereovision), building an image perspective, the use of fixed cameras and additional lighting of the object, and a special calibration of photo or video detector.In the present paper the authors develop a method of determining the distances to objects by analyzing a series of images using depth evaluation using defocusing. This method is based on the physical effect of the dependence of the determined distance to the object on the image from the focal length or aperture of the lens. When focusing the photodetector on the object at a certain distance, the other objects both closer and farther than a focal point, form a spot of blur depending on the distance to them in terms of images. Image blur of an object can be of different nature, it may be caused by the motion of the object or the detector, by the nature of the image boundaries of the object, by the object’s aggregate state, as well as by different settings of the photo-detector (focal length, shutter speed and aperture).When calculating the diameter of the blur spot it is assumed that blur at the point occurs equally in all directions. For more precise estimates of the geometrical parameters determination of the behavior and state of the object under study a statistical approach is used to determine the individual parameters and estimate their accuracy. A statistical approach is used to evaluate the deviation of the dependence of distance from the blur from different types of standard functions (logarithmic, exponential, linear). In the statistical approach the evaluation method of least squares and the method of least modules are included, as well as the Bayesian estimation, for which it is necessary to minimize the risks under different loss functions (quadratic, rectangular, linear) with known probability density (we consider normal, lognormal, Laplace, uniform distribution). As a result of the research it was established that the error variance of a function, the parameters of which are estimated using the least squares method, will be less than the error variance of the method of least modules, that is, the evaluation method of least squares is more stable. Also the errors’ estimation when using the method of least squares is unbiased, whereas the mathematical expectation when using the method of least modules is not zero, which indicates the displacement of error estimations. Therefore it is advisable to use the least squares method in the determination of the parameters of the function.In order to smooth out the possible outliers we use the Kalman filter to process the results of the initial observations and evaluation analysis, the method of least squares and the method of least three standard modules for the functions after applying the filter with different coefficients.


Complexity ◽  
2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
Mohammad Reza Mahmoudi ◽  
Marzieh Rahmati ◽  
Zulkefli Mansor ◽  
Amirhosein Mosavi ◽  
Shahab S. Band

The productivity of researchers and the impact of the work they do are a preoccupation of universities, research funding agencies, and sometimes even researchers themselves. The h-index (h) is the most popular of different metrics to measure these activities. This research deals with presenting a practical approach to model the h-index based on the total number of citations (NC) and the duration from the publishing of the first article (D1). To determine the effect of every factor (NC and D1) on h, we applied a set of simple nonlinear regression. The results indicated that both NC and D1 had a significant effect on h ( p  < 0.001). The determination of coefficient for these equations to estimate the h-index was 93.4% and 39.8%, respectively, which verified that the model based on NC had a better fit. Then, to record the simultaneous effects of NC and D1 on h, multiple nonlinear regression was applied. The results indicated that NC and D1 had a significant effect on h ( p  < 0.001). Also, the determination of coefficient for this equation to estimate h was 93.6%. Finally, to model and estimate the h-index, as a function of NC and D1, multiple nonlinear quartile regression was used. The goodness of the fitted model was also assessed.


2018 ◽  
Vol 64 (4) ◽  
pp. 407
Author(s):  
Jacqueline Isamar Muro-Ríos ◽  
R. Espinosa-Luna

Inspired in a recent theoretical work for the determination of the Mueller matrix, using as incidence a single classically entangled polarization state (F. Töppel et al., New J. Phys. 16 (2014) 073019), an experimental setup is proposed and tested.  The open space and two wave plate retarders are used as the transparent, nondepolarizing samples under study. Results show some experimental improvements are necessary in order to implement accurately the theoretical proposal in which this work is based.


2014 ◽  
Vol 24 (4) ◽  
pp. 320-325 ◽  
Author(s):  
Pilar Sainz de Baranda ◽  
María Rodríguez-Iniesta ◽  
Francisco Ayala ◽  
Fernando Santonja ◽  
Antonio Cejudo

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