scholarly journals Occurrence and Distribution of 17 Targeted Human Pharmaceuticals in Various Aquatic Environmental Matrices in Southeast Asia with Particular Reference to Malaysia: A Comprehensive Review

2021 ◽  
Vol 65 (3) ◽  
Author(s):  
Norbaya Hashim ◽  
Ali Yuzir ◽  
Fouad Fadhil Al-Qaim ◽  
Nasehir Khan E.M. Yahaya
Keyword(s):  
Drinking Water ◽  
Surface Water ◽  
Southeast Asia ◽  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Solid Phase ◽  
Domestic Wastewater ◽  
Municipal Wastewater Treatment ◽  
Environmental Matrices ◽  
Aqueous Matrices

Abstract. This review focuses on the occurrence and distribution of 17 targeted human pharmaceutical compounds from the most common therapeutic classes. These include one analgesic (acetaminophen), three non-steroidal anti-inflammatory drugs (NSAIDs) (acetylsalicylic acid, diclofenac, ibuprofen), two antidiabetic drugs (gliclazide, metformin), three antihistamines (cetirizine, chlorphenamine, ranitidine), four antihypertensives (amlodipine, atenolol, metoprolol, prazosin), one lipid regulator (simvastatin), one anti-convulsant (carbamazepine), one bronchodilator agent (salbutamol) and one stimulant (caffeine) which have been detected globally in various aquatic environmental matrices such as surface water, drinking water, ground water, seawater, influent and effluent of municipal wastewater treatment plants (WWTPs), hospital and industrial treatment plants, among others. The most common analytical method used involved solid phase extraction (SPE) and liquid chromatography coupled to mass spectrometry. The concentrations of all drugs investigated in all aqueous matrices varied from 0.5 to 85,000 ng/L for the highest concentration in the aqueous matrices in Southeast Asia. This review provides the first compilation on human pharmaceuticals in Southeast Asia in surface water, domestic wastewater (influent and effluent) and drinking water.   Resumen. Esta revisión se centró en la aparición y distribución de 17 fármacos de uso humano pertenecientes a las clases terapéuticas más comunes y consiste en un analgésico (acetaminofeno), tres medicamentos antiinflamatorios no esteroideos (AINE) (ácido acetilsalicílico, diclofenaco, ibuprofeno), dos antidiabéticos (gliclazida, metformina), tres antihistamínicos (cetirizina, clorfenamina, ranitidina), cuatro antihipertensivos ( atenolol, metoprolol, prazosina), un regulador de lípidos (simvastatina), un anticonvulsivo (carbamazepina), un agente broncodilatador (salbutamol) y un estimulante (cafeína), y que se han detectado globalmente en varios tipos de matrices ambientales acuáticas como el agua superficial, agua potable, agua subterránea, agua de mar, afluente y efluente de plantas de tratamiento de aguas residuales municipales (EDAR), plantas de tratamiento hospitalarias e industriales entre otras. El método analítico más utilizado involucró extracción en fase sólida (SPE) y cromatografía líquida acoplada a espectrometría de masas. Las concentraciones de todos los fármacos investigados en todas las matrices acuosas variaron de 0,5 a 85.000 ng / L, y presentaron la concentración más alta en las matrices acuosas en el país del sudeste asiático. Esta revisión proporciona el primer informe recopilatorio sobre un estudio de productos farmacéuticos humanos que se ha realizado en el sudeste asiático y se centra en aguas superficiales, aguas residuales domésticas (afluentes y efluentes) y agua potable.

scholarly journals The role of wastewater treatment plants in surface water contamination by plastic pollutants

2018 ◽  
Vol 45 ◽  
pp. 00054 ◽  
Author(s):  
Bozena Mrowiec
Keyword(s):  
Wastewater Treatment ◽  
Surface Water ◽  
Water Contamination ◽  
Membrane Filtration ◽  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Point Sources ◽  
Municipal Sewage ◽  
Municipal Wastewater Treatment ◽  
Surface Water Contamination

The aim of this paper was to review the literature data regarding the physico-chemical characteristic of plastic pollutants discharged with municipal sewage, the practical possibility of removing microplastic particles from wastewater during different treatment steps in WWTPs and the problem of surface water contamination within them. Microplastics (the size range of 1 nm to < 5 mm), have been recognized as an emerging threat, as well as an ecotoxicological and ecological risk for water ecosystems. Municipal wastewater treatment plants (WWTPs) are mentioned as the main point sources of microplastics in an aquatic environment. Microplastic particles can be effectively removed in the primary treatment zones via solids skimming and sludge settling processes. Different tertiary treatment processes such as: gravity sand filtration, discfilter, air flotation and membrane filtration provide substantial additional removal of microplastics, and the efficiency of wastewater treatment process can be at a removal level of 99.9%. Nevertheless, given the large volumes of effluent constantly discharged to receivers, even tertiary level WWTPs may constitute a considerable source of microplastics in the surface water.

Elimination of organic micro-contaminants in municipal wastewater by a combined immobilized biomass reactor and solar photo-Fenton tertiary treatment

2017 ◽  
Vol 20 (1) ◽  
Author(s):  
L. Prieto-Rodríguez ◽  
I. Oller ◽  
A. Agüera ◽  
S. Malato
Keyword(s):  
Municipal Wastewater ◽  
New Technologies ◽  
Wastewater Treatment Plants ◽  
Solid Phase ◽  
Municipal Wastewater Treatment ◽  
Tertiary Treatment ◽  
Conventional Activated Sludge ◽  
Immobilized Biomass ◽  
Municipal Wastewater Treatment Plants ◽  
Micro Pollutants

AbstractMunicipal wastewater treatment plants (MWTPs) have become one of the main sources of water for potential reuse. However, some pharmaceuticals, pesticides, hormones and others organics escape conventional wastewater treatments, and therefore, new technologies must be applied to overcome the problem. This article presents an efficient alternative that combines an aerobic immobilized biomass reactor (IBR) with a solar photo-Fenton process as a tertiary treatment. Real municipal wastewater was treated in the IBR system in batch and continuous modes. Micro-pollutants were monitored by using an advanced analytical procedure consisting of pre-concentration of samples by solid phase extraction (SPE) followed by liquid chromatography coupled to mass spectrometry. Results were compared with those observed in the MWTP secondary conventional activated sludge treatment. Effluents from the IBR, operating at the maximum treatment capacity, were treated in a previously optimized solar photo-Fenton pilot plant as a tertiary treatment to entirely eliminate remnant micro-pollutants.

scholarly journals LIQUID PHASE CHROMATOGRAPHIC METHODS APPLIED TO DETERMINE EMERGING CONTAMINANTS IN ENVIRONMENTAL SAMPLES

2020 ◽  
Vol 2 (1) ◽  
pp. 11-20
Author(s):  
Vasile Ion Iancu ◽  
Jana Petre ◽  
Toma Galaon ◽  
Gabriel Valentin Serban ◽  
Marcela Niculescu ◽  
...  
Keyword(s):  
Surface Water ◽  
Liquid Phase ◽  
Environmental Samples ◽  
Flame Retardants ◽  
Emerging Contaminants ◽  
Municipal Wastewater ◽  
Solid Phase ◽  
Endocrine Disrupting Chemicals ◽  
Municipal Wastewater Treatment ◽  
The Impact

Emerging contaminants are a heterogeneous group of chemicals that include daily personal care products and pharmaceuticals (PPCPs), flame retardants, endocrine-disrupting chemicals (EDCs) and nanoparticles (NPs) present in environment which are unregulated. In this review, we present the methods of analysis conducted by INCD-ECOIND regarding some classes of emerging contaminants (neonicotinoid pesticides, beta-blocker drugs) that are not regulated by the legislation, in different types of environmental samples (wastewater, surface water). The present review presents the selective solid-phase extraction (SPE) methods used for isolation of the targeted compounds from aqueous matrices and also the main instrumental parameters of the separation and detection process. After extraction, the compounds were subjected to liquid phase chromatographic separation with mass spectrometric detection (UHPLC-MS/MS). Finally, the methods were applied in the determination of compounds from different categories of water, carrying out studies on the efficiency of elimination of compounds in several municipal wastewater treatment plants (WWTPs). In addition, the impact of the treatment plants on some receiving surface water used to obtain drinking water was studied.

scholarly journals Fate and Removal of Pharmaceuticals and Illegal Drugs Present in Drinking Water and Wastewater

2017 ◽  
Vol 24 (1) ◽  
pp. 65-85 ◽  
Author(s):  
Anna Szymonik ◽  
Joanna Lach ◽  
Krystyna Malińska
Keyword(s):  
Drinking Water ◽  
Wastewater Treatment ◽  
Surface Water ◽  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Rapid Development ◽  
Diclofenac Sodium ◽  
Clofibric Acid ◽  
Treated Wastewater ◽  
Illegal Drugs

Abstract Rapid development of pharmaceutical industry, and thus widespread availability of different types of therapeutical and increased intake of pharmaceuticals, results in elevated concentrations of pharmaceuticals in municipal wastewater subjected to treatment in wastewater treatment plants. Pharmaceuticals present in raw wastewater discharged from hospitals, households, veterinary and health care clinics eventually end up in wastewater treatment plants. Commonly applied methods for treating wastewater do not allow complete removal of these contaminants. As a consequence, pharmaceuticals still present in treated wastewater are introduced to water environment. The most frequently identified pharmaceuticals in surface water belong to the following groups: non steroidal anti inflammatory drugs, beta-blockers, estrogens and lipid regulators. The most difficult is removal of diclofenac, clofibric acid and carbamazepine as these substances show low biodegradability. Diclofenac can be removed in the process of wastewater treatment by 40%, carbamazepine by 10%, and clofibric acid from 26 to 50%. The presence of diclofenac sodium in the rivers in Poland was confirmed and the concentrations were following: 380 ng/dm3 (the Warta river), 470 ng/dm3 (the Odra river), 140 ng/dm3 (the Vistula river). Naproxene was found in the Warta river at the concentration of 100 ng/dm3. The presence of pharmaceuticals in surface water can be toxic to aqueous microorganisms and fish. Recent studies confirmed also the presence of pharmaceuticals in drinking water. This is considered as a problem especially in urban agglomerations such as Berlin or large cities in Spain and China. The studies showed that pharmaceuticals were also identified in the samples taken from the Polish rivers and drinking water. The presence of naproxene and diclofenac at the concentrations of 13 and 4 ng/dm3 was identified in drinking water sampled from water intakes in Poznan. Surface water and drinking water showed also the presence of illegal drugs.

scholarly journals Evaluation of the Possibility of Using Hydroponic Cultivations for the Removal of Pharmaceuticals and Endocrine Disrupting Compounds in Municipal Sewage Treatment Plants

Molecules ◽  
2019 ◽  
Vol 25 (1) ◽  
pp. 162 ◽  
Author(s):  
Daniel Wolecki ◽  
Magda Caban ◽  
Magdalena Pazda ◽  
Piotr Stepnowski ◽  
Jolanta Kumirska
Keyword(s):  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Solid Phase ◽  
Sewage Treatment ◽  
Endocrine Disrupting Compounds ◽  
Municipal Sewage ◽  
Municipal Wastewater Treatment ◽  
Plant Materials ◽  
Euonymus Europaeus ◽  
Endocrine Disrupting

The problem of the presence of pharmaceuticals and endocrine disrupting compounds (EDCs) in the environment is closely related to municipal wastewater and in consequence to municipal wastewater treatment plants (MWWTPs) because wastewater is the main way in which these compounds are transferred to the ecosystem. For this reason, the development of cheap, simple but very effective techniques for the removal of such residues from wastewater is very important. In this study, the analysis of the potential of using three new plants: Cyperus papyrus (Papyrus), Lysimachia nemorum (Yellow pimpernel), and Euonymus europaeus (European spindle) by hydroponic cultivation for the removal of 15 selected pharmaceuticals and endocrine disrupting compounds (EDCs) in an MWWTP is presented. In order to obtain the most reliable data, this study was performed using real WWTP conditions and with the determination of the selected analytes in untreated sewage, treated sewage, and in plant materials. For determining the target compounds in plant materials, an Accelerated Solvent Extraction (ASE)-Solid-Phase Extraction (SPE)-GC-MS(SIM) method was developed and validated. The obtained data proved that the elimination efficiency of the investigated substances from wastewater was in the range of 35.8% for diflunisal to above 99.9% for paracetamol, terbutaline, and flurbiprofen. Lysimachia nemorum was the most effective for the uptake of target compounds among the tested plant species. Thus, the application of constructed wetlands for supporting conventional MWWTPs allowed a significant increase in their removal from the wastewater stream.

scholarly journals Performance Assessment of Domestic Wastewater Treatment Plants Operating on Different Technologies

2020 ◽  
Vol 9 (3) ◽  
pp. 1649-1653
Keyword(s):  
Water Quality ◽  
Surface Water ◽  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Sewage Treatment ◽  
Drainage System ◽  
Surface Water Quality ◽  
Domestic Wastewater ◽  
Effluent Quality

Delhi, the most populated city in the country, is the capital of India. The huge population, urbanization and industrial processes contribute to degradation of water quality which is further aggravated by direct disposal of untreated domestic wastewater into the river Yamuna. In Delhi, the sewerage system is badly affected by improper management of the drainage system and insufficient installation of sewers in undeveloped as well as slum areas of the city which degrade the surface water quality of Yamuna River and create unhygienic conditions for the increasing population. In this study, three sewage treatment plants (STPs) have been selected which are situated at Najafgarh, Delhi Gate and Shahdara based on different technologies like Extended Aeration (EA), Biological Filtration and Oxygenated Reactor (BIOFOR) and Phytorid in order to assess the quality of wastewater before and after treatment and determining the removal efficiencies of various parameters. The study reveals that the performance of Delhi Gate and Shahdara STPs based on BIOFOR and Phytorid technologies are more efficient for the treatment of the municipal wastewater which can be further be safely disposed off into surface water and can be used for non-domestic purposes like irrigation, agriculture, cleaning of parks and streets. The effluent quality of Najafgarh STP based on EA technology is found to be less efficient as compared to the BIOFOR and Phytorid technologies. Hence, it is required to be operated and maintained properly with close supervision so as to achieve effluent quality standards as prescribed by the Indian standards

scholarly journals PHOSPHORUS RECOVERY FROM WASTE AS STRUVITE

2020 ◽  
pp. 34-44
Author(s):  
Gergana Peeva ◽  
Ralitza Koleva ◽  
Maya Stancheva ◽  
Husein Yemendzhiev ◽  
Valentin Nenov
Keyword(s):  
Municipal Wastewater ◽  
Wastewater Treatment Plants ◽  
Domestic Wastewater ◽  
Nutrient Content ◽  
Animal Manure ◽  
Phosphorus Recovery ◽  
Phosphorus Compounds ◽  
Mineral Fertilizers ◽  
Secondary Source ◽  
Municipal Wastewater Treatment

The paper gives information on the depletion of phosphorus (P) as an important element for all forms of life and its pollution impact on the environment in case of intensive discharge of phosphorus compounds into water bodies. Two secondary waste sources of Phosphorus are under consideration, namely the domestic wastewater and sludge and animal manure. The characteristics of these two fluids regarding organic matter and nutrient content are summarized. Discussing the techniques for P extraction mostly attention is given to phosphorus precipitation as ammonium magnesium phosphate (struvite). Examples of effectiveness of P precipitation as struvite in Municipal Wastewater Treatment Plants (MWWTPs) with chemical and biological P removal are presented. The examples of struvite production from sewage and manure waste show evidently the great potential of utilization of such a waste as a source of phosphorus. The recovered product is valuable both as it is a slow release fertilizer and with its low content of heavy metals compared to the mineral fertilizers. In respect of the diminishing amount of natural P rocks, the sewagec wastewater and sludge and the animal manure can be regarded as an important secondary source of Phosphorus.

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