scholarly journals Herd immunity to SARS-COV-2 in the population of the Southern regions of the Far East of Russia

2021 ◽  
Vol 6 (5) ◽  
pp. 253-273
Author(s):  
A. Yu. Popova ◽  
V. S. Smirnov ◽  
E. B. Ezhlova ◽  
A. A. Melnikova ◽  
O. E. Trotsenko ◽  
...  
Keyword(s):  
Statistical Significance ◽  
Herd Immunity ◽  
Far East ◽  
Amur Region ◽  
Reproductive Number ◽  
Pasteur Institute ◽  
Scientific Center ◽  
Cross Sectional ◽  
Population Immunity ◽  
The Far East

The aim: to study the structure and dynamics of population immunity to SARSCoV-2 of the population of the Southern Regions of the Far East (SRFE): Khabarovsk, Primorsky Krai and Amur Region during the COVID-19 epidemic in 2020.Materials and methods. The work was carried out according to the program for assessing population immunity to SARS -CoV-2 of the population of the Russian Federation according to the methodology developed by the Rospotrebnadzor with the  participation of the St.  Petersburg Pasteur Institute. The study was approved by  the  ethical committee of the St.  Petersburg Pasteur Institute. The selection of participants was carried out by a questionnaire method using cloud technologies. The  volunteers were randomized by age by stratification into 7  age groups: 1–17, 18–29, 30–39, 40–49, 50–59, 60–69, 70+ years old. Territorial randomization consisted in limiting the engaging of volunteers – no more than 30 people from one enterprise. After the initial cross-sectional study, a 3-stage seromonitoring was carried out, in which the same volunteers participated. Antibodies to the SARS-CoV-2 nucleocapsid were determined in peripheral blood serum by the enzyme immunoassay using an appropriate set of reagents produced by the State Scientific Center for Medical and Biological Sciences of the Rospotrebnadzor (Obolensk). Statistical analysis was performed using the Excel package. The confidence interval for the proportion was calculated using the A. Wald, J. Wolfowitz method with A. Agresti, B.A. Coull’s correction. The statistical significance of the differences was calculated online using a specialized calculator. The statistical significance of the differences was assessed with a probability of p˂ 0.05, unless otherwise indicated.Results. In a comparative analysis, the highest morbidity was observed in the Khabarovsk Territory, the lowest – in the Primorsky Territory. The level of seroprevalence among the population of the region was 19.6 % (95 % CI: 18.2–21.1) in  the  Khabarovsk Territory, 19.6  % (95  %  CI: 18.1–21.2) in the Primorsky Territory19,6 % and 45,5 % (95 % CI: 43.7–47.3) in the Amur region. The highest seroprevalence was noted among 1–17 years old children, mainly due to the subgroup of 14–17-years-olds. The smallest proportion of seropositive was found among 40–49-year-olds in the Khabarovsk Territory (14.7 %, 95 % CI: 11.2–18.6), 18–28-yearolds in the Primorsky Territory (13.3 %, 95 % CI: 10.0–17.1) and 30–39-year-olds in the Amur Region (36.3  %, 95%  CI:  31.7–41.6). No statistically significant dependence of  seroprevalence on territorial and occupational factors has been established, with the exception of an increase in the proportion of seropositive medical workers in Primorsky Territory. In the process of 3-stage seromonitoring, a regular increase in the proportion of seropositive people was revealed in all SRFE. The resulting tendency is correctly described by a second-order polynomial. A relationship was revealed between the number of convalescents and persons in contact with them, which made it possible to calculate the base reproductive number (R0) in the range from 1.4 (Primorsky Territory) to 2.4 (Amur Region). Analysis of seroprevalent volunteers showed that the number of asymptomatic individuals varied from 94.1 % (95 % CI: 92.8–95.3) to 98.3 % (95 % CI: 98.8–99.2). This indicates that most of the volunteers had COVID-19 asymptomatically.Conclusions. A comparative study showed the prevalence of seroprevalence in the Amur Region compared with the Khabarovsk and Primorsky Territories. The relationship between the number of convalescents and persons in contact with them was noted. The value of the base R0 is calculated. It has been shown that more than 90 % of seropositive individuals in the COVID-10 SRFE were asymptomatic.

SARS-CoV-2 Herd Immunity of the Kyrgyz Population in 2021

2021 ◽  
Author(s):  
Anna Y. Popova ◽  
Omor T. Kasymov ◽  
Vyacheslav Y. Smolenski ◽  
Вячеслав Смирнов ◽  
Svetlana A. Egorova ◽  
...  
Keyword(s):  
Randomized Study ◽  
Herd Immunity ◽  
Statistical Processing ◽  
Cloud Service ◽  
Asymptomatic Infection ◽  
Enzyme Linked Immunosorbent Assay ◽  
Pasteur Institute ◽  
Cross Sectional ◽  
Saint Petersburg ◽  
Kyrgyz Population

Abstract Background. In the fight against coronavirus infection, an important direction is control of herd immunity to the pathogen. SARS-CoV-2 herd immunity is formed naturally as a result of manifest or asymptomatic infection, or artificially as a result of vaccination Aim: To assess the SARS-CoV-2 herd immunity status of the Kyrgyz population. Materials and methods. A cross-sectional, randomized study of SARS-CoV-2 herd immunity was carried out according to a program developed by Rospotrebnadzor, with the participation of the Saint Petersburg Pasteur Institute, taking into account WHO recommendations. In all study stages cloud service (internet) technologies were used. The ethics committees of the Preventive Medicine Association (Kyrgyzstan) and the Saint Petersburg Pasteur Institute (Russia) approved the study. A total of 9,471 volunteers were selected, representing 0.15% (95% CI 0.14-0.15) of the total population. They were randomized according to age and region. Antibodies (Abs) to the nucleocapsid antigen (Nag) were determined by enzyme-linked immunosorbent assay (ELISA) of volunteer blood plasma. For vaccinated individuals, Abs to the SARS-CoV-2 receptor-binding domain antigen (RBDag) were determined. Statistical processing of the results was carried out using Excel 2010 and other programs. Differences were designated as statistically significant at p<0.05. Results. The seroprevalence of the general population was 48.7% (95% CI 47.7-49.7), with a maximum in the group of '60-69 year old' (59.2% (56.6-61.7)) and a minimum in the group '1-17 y.o.' (32.7% (95 CI 29.4-36.1)). The largest proportion seropositive was found in the Chui region (51.3% (95% CI 47.9-54.8)). The lowest was in Osh city (38.1% (95 CI 32.6-43.9)). The maximum seropositivity was detected among healthcare workers (57.1% (95% CI 55.4-58.8); the minimum was noted among artists (38.6% (95% CI 26.0-52.4)). Asymptomatic SARS-CoV-2 positivity was 79.1% (96% CI 77.9-80.3). Vaccination with Sputnik V, EpiVacCorona, or Sinopharm formed comparable levels of immunity. Conclusions. The herd immunity to SARS-CoV-2 Nag is 48.75% (95% CI 47.7-49.7), and the overall immunity (Nag + RBDag) is 57%.

AMUR RIVER TRANSPORT IN INTERACTION OF THE AMUR REGION (RUSSIA) AND THE HEILONGJIANG PROVINCE (CHINA) IN THE 1990S

2021 ◽  
Vol 10 (2) ◽  
pp. 30-48
Author(s):  
YING СAI ◽  
Keyword(s):  
Far East ◽  
Amur Region ◽  
Amur River ◽  
River Transport ◽  
The Far East ◽  
Archival Documents ◽  
The Amur River ◽  
Chinese Province ◽  
Rela Tions ◽  
Transport Potential

The purpose of the article is to analyze the significance of the Amur River transport activity in the 1990s for interregional Russian-Chinese cross-border coopera-tion in the Far East. Using the materials in Chinese as well as archival documents, the author examines the process of border ties resumption between Russia and China in the Far East after the normalization of rela-tions between the countries. The peculiarities of the river fleet functioning on the Amur during the period of socio-economic reforms of the last decade of the 20th century in Russia are studied. The characteristic of the Amur River transport potential is presented. The prob-lems of the Amur River transport in the development of cooperation between the Russian Amur Region and the Chinese province of Heilongjiang in the context of Rus-sian-Chinese relations at the interstate and interregion-al levels are structured.

scholarly journals Impact of forest growth conditions on the wood density: the case of Amur Region

2018 ◽  
Vol 60 (4) ◽  
pp. 292-298
Author(s):  
Natalia A. Romanova ◽  
Alexander B. Zhirnov ◽  
Natalia A. Yust ◽  
Xu Fucheng
Keyword(s):  
Wood Density ◽  
Far East ◽  
Growth Conditions ◽  
Amur Region ◽  
Forest Growth ◽  
Far East Of Russia ◽  
Density Determination ◽  
The Far East ◽  
First Time

Abstract The problem of determining the dependence of the chainsaw on the density of wood, substantiation of effective options for the number of chainsaws in the assortment and whiplash method of logging is quite relevant. In the Far East of Russia, in particular, in the Amur region, the forest growth conditions are different from the western ones, and therefore, the properties of the wood differ from the generally accepted ones. The article describes forest growth conditions that influence the properties of the wood in areas of the Amur region. Using the method of density determination, the density of larch, pine and birch were studied for first time in the areas of the region. The dependence of the density on humidity, age, species, season of the year and the area of growth was found out. The results of the research showed that under humidity of 70%, the density of larch was 1088.99 kg/m3, it was 919.8 kg/m3 for pine and it was for birch 915.9 kg/m3.

scholarly journals Conflict of the Khabarovsk City Duma and the Provisional Government of the Far East in 1920

2020 ◽  
Vol 3 ◽  
pp. 96-107
Author(s):  
F. А. Popov
Keyword(s):  
Political Instability ◽  
Far East ◽  
Amur Region ◽  
City Government ◽  
Regional Government ◽  
Declaration Of Independence ◽  
The Far East ◽  
Unilateral Declaration ◽  
The Right ◽  
Far Eastern

The article analyzes the confrontation between the Khabarovsk city government of the "Kolchak convocation" and the regional government of Primorye formed as a result of the anti-Kolchak coup on January 31, 1920. The parallel existence of several state formations in the Far East created the ground for political instability. The conflict between the Khabarovsk Duma and the Vladivostok government was complicated by an ideological factor: most Duma members belonged to the right, anti-communist camp, while the regional government consisted mainly of socialists. The refusal of both sides to compromise resulted in the unilateral declaration of "independence" of Khabarovsk in August 1920. The evacuation of Japanese troops and the lack of support for the actions of the Duma among the townspeople led to the "separatists" to failure. The conflict was seized by the rivals of Primorye in the unification of the Far East – the Far Eastern Republic and the Soviet Amur Region – the latter's troops, contrary to the protest of the Vladivostok government, occupied Khabarovsk in October 1920.

scholarly journals Dinosaurs from the location of Gilchins vertebrates of the late Mesozoic era (Russia, Amur region)

2019 ◽  
Vol 9 (1) ◽  
pp. 9-26
Author(s):  
I.A. Ermatsans ◽  
Yu.L. Bolotsky ◽  
I.Yu. Bolotsky ◽  
G.N. Gataulina
Keyword(s):  
Far East ◽  
Amur Region ◽  
Fossil Bone ◽  
Scientific Center ◽  
Late Mesozoic ◽  
Fossil Material ◽  
New Information ◽  
History Of ◽  
Academy Of Sciences ◽  
Bone Remains

Currently there are six locations of Cretaceous continental fauna and flora in Amur region: Blagoveshchensk, Kundur and Astashikha, Gilchin, Dim, Bureinsky Belogory. Gilchin is the location of the Cretaceous dinosaurs, the potential of which still requires evaluation. The article provides new information about the history of its discovery, as well as the description of the fossils from the Gilchin collection presented in the exposition of the Paleontological Museum of the Amur Scientific Center of the Far East Branch of the Russian Academy of Sciences. The fauna of Gilchin, established by fossil bone remains, includes hadrosaurs, carnivorous dinosaurs, a dinosaur whose identity it is difficult to determine, and turtles (Trionychidae indet). Most of the definable bone remains of the collection belong to the hadrosaurs. In terms of preservation, the fossil material is close to that of the Chinese locations of Ulaga and Jiayin / Longu Shan. The article assumes similarity of the genesis of the locations of Gilchin and Jiayin / Longu Shan (China).

scholarly journals Strategies for vaccination agains SARS-COV-2 to efficiently bring R<1

2021 ◽  
Author(s):  
André Voigt ◽  
Stig W. Omholt ◽  
Eivind Almaas
Keyword(s):  
Computer Simulations ◽  
Herd Immunity ◽  
Random Selection ◽  
Reproductive Number ◽  
High Fidelity ◽  
Wide Spread ◽  
Limited Availability ◽  
Population Immunity ◽  
The Common ◽  
Limited Supply

ABSTRACTWith limited availability of vaccines, an efficient use of the limited supply of vaccines in order to achieve herd immunity will be an important tool to combat the wide-spread prevalence of COVID-19. Here, we propose a targeted vaccination approach (EHR) that provides a significant reduction in the necessary number of doses needed achieve herd immunity compared to age-prioritized and random selection vaccination schemes. Using high-fidelity individual-based computer simulations with Oslo, Norway as an example, we find that for a community reproductive number in a setting where R=1.4 without population immunity, the EHR method reaches herd immunity at only 15% of the population vaccinated, whereas the common age-prioritized approach needs 40%. With R=1.9 in the absence of immunity, EHR needs 30% and age-prioritized needs 52%.

scholarly journals DEPRESSION AS A DESTABILIZING FACTOR OF THE MENTAL RESOURCES OF THE GROWING GENERATION OF THE FAR EAST

2020 ◽  
Vol 17 (4) ◽  
pp. 181-186
Author(s):  
E.A. Levkova ◽  
◽  
I.P. Loginov ◽  
S.Z. Savin ◽  
S.G. Gevorkyan ◽  
...  
Keyword(s):  
Depressive Disorders ◽  
Far East ◽  
Amur Region ◽  
Psychological Resources ◽  
Social Mechanisms ◽  
Khabarovsk Krai ◽  
The Far East ◽  
Mental Resources ◽  
Growing Population

The article analyzes the risks of the influence of depressive disorders on the psychological resources of the growing population of the Amur region of the Khabarovsk krai. It was revealed that depressive disorders can act in isolation or in combination with other somatic and psychopathological manifestations. Various genetic, constitutional, psychogenic and social mechanisms are involved in the formation of these states, and the forecast of the risk of impact on psychological resources depends on the microsocial speed within which they are realized

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