Dynamics of quality of life indicators of patients with hemorrhagic hemisphere stroke at the early recovery period of the disease

Author(s):  
S. O. Medvedkova ◽  
A. O. Dronova

Objective — to investigate the indicators of the quality of life in patients suffering from a hemorrhagic hemispherestroke in the early recovery period in dynamics using SF‑36v2 questionnaire and to reveal the factors which affect these indicators. Methods and subjects. An open‑label, cohort study of 46 patients suffering from a hemorrhagic hemispherestroke (HHS) in the early recovery period was performed in ZSMU nervous diseases clinic. Among the patients there were 31 (67.4 %) men and 15 (32.6 %) women. The average age of the patients was 57.15 ± 9.53 years. The patients underwent comprehensive investigation of HHS on the 30th, 90th, and 180th day of the disease using the following scales: National Institutes of Health Stroke Scale (NIHSS) to objectively evaluate the condition severity; Modified Rankin Scale (mRS) to assess the rate of functional recuperation and disability; Barthel Index (BI) to evaluate the possibility of everyday skills and self‑care; Motor Assessment Scale (MAS) to indicate the muscle spasticity in the upper and lower limbs; quality of life assessment according to the SF‑36v2 Health Survey questionnaire. Results. The study found that significant decrease of all life quality indicators, evaluated on SF‑36v2 scale, was observed on the 30th day of HHS patients. The physical functioning, the physical role functioning, and the social role functioning section scores were the most decreased. A reliable improvement of the physical and mental part of health during the early recovery period was observed. Conclusions. A statistically significant correlation was found between the NIHSS, mRS, BI scores and all quality of life indicators according to SF‑36v2, except for the intensity of pain on the 30th day of the disease. A statistically significant effect of the presence of manifestations of spasticity on the physical component of health during the early recovery period, as well as on the indicator of pain intensity on the 30th day of the disease, was established.  

2020 ◽  
Vol 16 (2) ◽  
pp. 16-22
Author(s):  
O.A. Alifer

Relevance. Hypertension is one of the most common chronic diseases, for which currently the goal of therapy is not so much recovery as improving circulatory function with a satisfactory quality of life. Objective: to determine the impact of different degrees of hypertension on quality of life in female and male patients. Materials and methods. 126 patients with arterial hypertension underwent examination, including 86 women (68%), 40 men (32%) aged 40 to 81 years (mean age 61.9 ± 0.3 years). Arterial hypertension of I degree had 19 people (15.1%), II degree - 65 patients (51.6%), III degree - 42 people (33.3%). The control group consisted of 43 healthy individuals who did not differ from the main group in terms of demographics. Surveys of patients to assess the quality of life conducted with the questionnaire SF-36 (Short Form-36) at each follow-up. Quality of life indicators has value in points. Results. The analysis of quality of life indicators in the group of healthy people found that the level of quality of life in men is much higher than in healthy women: "physical pain", "role functioning" - P1-P2> 0.5; "Physical functioning" - P1-P2 <0.001; "Physical health" - P1-P2> 0.5, except for the scale "general health" - P1-P2 <0.05 (77.2 ± 3.02 vs. 63.75 ± 2.81). The comparison of the quality of life of patients with hypertension of I degree and patients with arterial hypertension of III degrees found reliable differences on the scales "Vitality" (P1-P3 <0.001), and "Social functioning" (P1-P3 <0.5). In patients with II and III degrees of arterial hypertension indicators of quality of life were low in themselves and differed on a scale "role functioning" of the questionnaire: "Vital force" (P2-P3> 0,5); "Role functioning" (P2-P3 <0.5); "Mental health" (P2-P3> 0.5). Patients with hypertension of the I degree in comparison with arterial hypertension of the II degree had reliably higher indicators of quality of life on scales "vital force" (80,0 ± 3,93 points) and "role functioning" (77,1 ± 4,04 points) ), but reduced indicators of "social functioning" and "mental health" (48.7 ± 7.35 and 47.41 ± 2.39 points, respectively). Patients with hypertension of I degree and III degree showed reliable differences on the scales "vital force" (P1-P3 <0.001) and "social functioning" (P1-P3 <0.5); and patients with hypertension of II and III degrees showed a significant decrease in all indicators of quality of life, especially on the scales "social functioning" and "mental health" (up to 31.5 ± 5.19 and up to 40.31 ± 2.23 points, respectively). Patients with hypertension of I degree had a decrease in general health (87.1 ± 3.16), physical function (82.6 ± 2.86), and physical pain (87.1 ± 3.16). Patients with II degree of hypertension had a significant reduction in role functioning (32.4 ± 5.19), physical pain, and general health (36.0 ± 6.12 and 42.26 ± 2.68 points, respectively). Conclusions. Hypertension significantly affects the quality of life. The state of health of patients with hypertension significantly limited their physical activity.


Purpose. To analyze quality of life dynamics of patients with trophic venous ulcers of the lower limbs after the treatment with the use of photodynamic therapy. Materials and methods. Quality of life research was conducted in 57 patients with trophic ulcers of venous etiology. The first group included 30 patients who received standard treatment, the second group — 27 patients, in which standard treatment was combined with a course of photodynamic therapy. To assess the quality of life of the patients in both groups, a questionnaire was conducted using the EuroQol-5D-5L survey system and the visual analogue scale EQ-VAS. The quality of life assessment was carried out at the beginning of treatment, 10 days and 6 weeks after starting treatment. Results. The results indicate a significant improvement in the quality of life in both groups, but the degree of improvement in this indicator in group 2 was 20.7 % higher.An analysis of the dynamics of improvement in quality of life showed an increase in the mean of the indicator 10 days after the beginning of treatment in patients in the first group of 26.7 %, the second group by 43 %, and in 6 weeks, its increase was achieved in patients in the first group by 32.7 %, in the second group — by 53.4 %. Conclusions. The use of photodynamic therapy in the treatment of venous trophic ulcers significantly affects the quality of life, which is manifested in the anti-inflammatory effect and reduction of pain syndrome in the shorter term (by 76.2 %), compared with patients in the first group.


2020 ◽  
Vol 20 (1) ◽  
pp. 123-127
Author(s):  
E Kaerova ◽  
N Zhuravskaya ◽  
O Shakirova ◽  
T Stebliy ◽  
S Popik

Aim. The article deals with searching for the new effective methods of physical rehabilitation in stroke patients. Materials and Methods. The program of physical rehabilitation involved 42 patients aged from 30 to 80 years with the consequences of ischemic stroke in the early reco­very period (up to six months), movement disorders, imbalances and postural disorders, reduced self-care capacity and mobility, reduced quality of life. The program included exercises with balancing platforms and training sessions on a force platform with biofeedback. Results. Comparative analysis revealed the positive dynamics of the balance function and balance when walking. The area of the center of pressure and its oscillations measured in the frontal and sagittal planes changed significantly, the velocity of the center of pressure, the maximum amplitude in the frontal plane, and the area of the statokinesiogram decreased. Conclusion. Comprehensive physical rehabilitation with balancing platforms and training on a force platform in the early recovery period helps to improve motor skills and balance, as well as to improve the quality of life and mobility of stroke patients.


2020 ◽  
Author(s):  
Fei Jing ◽  
Haina Fan ◽  
Zhimin Zhao ◽  
Feng Xing ◽  
Yingchun He ◽  
...  

Abstract Background: Some patients with COVID-19 have been found pulmonary dysfunction and/or fibrosis in the recovery period, especially severe cases, but there are no certain drugs or treatment to cope with this situation. Previous studies proved the efficacy of FZHY on lung fibrosis induced by Bleomycin in animals and improvement of pulmonary function in COPD patients. We design this trial to carry out the clinical study that the effects of FZHY Tablets on pulmonary fibrosis and/or pulmonary function injury in the recovery period of COVID-19 and expect to improve the prognosis.Methods/design: This is a double-blind, placebo-controlled, randomized, multicenter clinical trial. It enrolls 160 patients who had been diagnosed with COVID-19, but currently they are negative for viral testing and have developed pulmonary fibrosis or pulmonary dysfunction. They are randomly divided equally into control group and experimental group. All patients are given basic treatment such as respiratory function rehabilitation training and vitamin C. The control group is given placebo of FZHY, and the experimental group is given FZHY. Each patient will be observed for 24 weeks and followed up for 8 weeks. The primary outcome for the trial is a composite endpoint consisting of lung function and HRCT. Secondary outcomes include clinical symptoms, oxygen saturation and quality of life assessment. Discussion: The trial is designed to test the hypothesis that treating pulmonary fibrosis or pulmonary dysfunction after SARS-CoV-2 infection with FZHY will improve the patient’s lung function or the pathological manifestation of pulmonary fibrosis, and improve the quality of life. Trial registration: Clinical Trials.gov, ID: NCT04279197. Registered on 12 April 2020.


2019 ◽  
Vol 13 (Supl 1) ◽  
pp. 40S
Author(s):  
Wrgelles Godinho Bordone Pires ◽  
Roberto Zambelli De Almeida Pinto ◽  
Philipe Eduardo Carvalho Maia ◽  
Rodrigo Simões Castilho ◽  
Felipe Daniel Vasconcelos de Carvalho ◽  
...  

Objective: The objective of this study is to perform a functional and quality of life assessment of patients subjected to debridement of ulcers in the posterior region of the ankle, which progressed to complete Achilles tendon resection without any type of tendon reconstruction or transfer. Methods: This is a case series of 4 patients, mostly diabetic, who underwent complete resection of an exposed and degenerated Achilles tendon due to ulcer in the posterior region of the ankle that precluded preservation given the need to control the infectious process considering the diagnosis of calcaneal osteomyelitis. This diagnosis was compatible with changes observed in the magnetic resonance imaging evaluation and was confirmed in cultures of bone tissue removed during debridement. The patients filled out the Brazilian Portuguese version of the Achilles Tendon Total Rupture Score (ATRS-BR) and 36-Item Short Form Survey (SF-36) during the postoperative period, and follow-up ranged from 6 to 24 months. The ATRS score ranges from 0 to 100, and the higher the scores are, the fewer symptoms and limitations the patients have. The SF-36 consists of 36 questions covering 8 domains: physical role functioning, physical functioning, bodily pain, general health perceptions, social role functioning, vitality, mental health and emotional role functioning. The items are independently assessed, and the total possible score is 100 points, which is indicative of the best health status. Results: All 4 Achilles tendons were approached. The mean age of the patients was 69.8 years. The mean score on the physical functioning section of the SF-36 was 63.8 points. When comparing the outcome with literature data, we observed that when patients with ulcers were compared with individuals of a similar age group, our study showed better results than previous studies. The mean score of the ATRS-BR was 46.3 points, which suggests a poor outcome. However, the patients had few complaints about their physical functioning, as shown in the SF-36 analysis. The decision not to perform Achilles tendon reconstruction was made jointly by the medical team and the patients and their families. Conclusion: Not reconstructing the Achilles tendon in patients, mostly elderly diabetic patients with posterior ankle ulcers, led to encouraging functional scores. The present study suggests that this type of ulcer treatment is a viable option for such populations.


Author(s):  
S. Fedorenko ◽  
О. Lazarieva ◽  
V. Vitomskyi ◽  
M. Vitomska

Quality of life indicators are key in assessing the effectiveness of physical therapy now, as they reflect the physical, psychological and social functioning of the individual. Objective: to determine the dynamics of quality of life in outpatients with disorders of orthopedic profile during a course of physical therapy, depending on the type of attitude to the disease. Research methods: quality of life assessment was conducted using the internationally standardized Health Status Survey. Patient grouping was performed using the International Classification of Functioning and the method of determining types of attitudes to the disease. The obtained results were processed by methods of mathematical statistics. The study involved 113 patients who underwent a course of physical therapy at FESCO Medical Center during 2013-2015. Results. The analysis revealed a number of features of the dynamics of quality of life depending on the localization of damage to the musculoskeletal system and the type of attitude to the disease. In particular, among lower-impaired patients group with irrational attitude to the disease had worse dynamics in the scales “physical functioning”, “role limitations due to physical health”, “pain”, “vitality”, “mental health” and "physical status". Because the dynamics in the groups with irrational attitude to the disease were statistically worse in a significant number of indicators, no comparison of the final indicators with the groups of patients with the rational attitude to the disease was observed. Conclusion. The existence of statistically significant differences in the dynamics of quality of life among patients with orthopedic profile during physical therapy at the outpatient stage was confirmed, depending on the type of attitude to the disease. The results obtained should be considered to improve the physical therapy system and increase its effectiveness. This is necessary first of all for patients with irrational attitude to the disease, as a significant number of the studied indicators were worse in these patients, and also had less pronounced dynamics compared to patients with rational psychotypes. This requires identifying the characteristics of managing such patients and improving management in the physical therapy system.


Author(s):  
A. Vazhenina ◽  
I. Ivanova ◽  
V. Skvarnik ◽  
T. Kapustina ◽  
R. Kadyrov

Results of quality of life assessment among adolescents – pupils of senior classes in municipal organizations of secondary education in Vladivostok – are presented in the article. Survey of 304 adolescents aged 15-17 years was conducted, and parameters of the physical and psychological component of health were studied. The obtained data indicate presence of gender and age peculiarities in the quality of life in high school students, including development of social and physical functioning under the influence of intensive psychophysiological body restructuring and active socialization of adolescents.


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