scholarly journals Evaluation of the anti-diarrheal and anti-ulcer activity of hydro-alcoholic extract of aerial part of Tridax procumbens in experimental rats

2021 ◽  
Vol 6 (3) ◽  
pp. 65-74
Author(s):  
Megha Chouhan ◽  
Rahul Saxena ◽  
Harsh Patidar
Keyword(s):  
Aerial Part ◽  
Alcoholic Extract ◽  
Tridax Procumbens

scholarly journals Phytochemical Screening, Biological Studiesand GC-MS Analysis of Extract of Biden pilosa L

2019 ◽  
Vol 5 (1) ◽  
pp. 79-93
Author(s):  
Dharma Prasad Khanal ◽  
Rupa Rana ◽  
Bechan Raut ◽  
Rabindra Prasad Dhakal
Keyword(s):  
Ethyl Acetate ◽  
Aerial Part ◽  
Inflammatory Activity ◽  
Alcoholic Extract ◽  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
Bidens Pilosa ◽  
Aerial Parts ◽  
Ms Analysis ◽  
Anti Inflammatory

Objective: The aim of the research work was to carry out the extraction of areal parts of Biden pilosa L by hydroalcholic and Hexane, ethyl acetate and acetone mixture followed by qualitative phytochemical analysis, acute oral toxicity test, anti-inflammatory test and GC-MS analysis of the extracts. Method: The hydro-alcoholic and HEA(n-hexane, ethyl acetate and acetone) extraction was done from aerial parts using ethanol and water in the ratio 70:30 and n-hexane, ethyl acetate and acetone in the ratio of 1:1:1 (HEA extract)  respectively. Acute oral toxicity testwas performed OECD guidelines. The single spot in TLC was obtained using n-hexane as solvent for HEA fraction and finally phytocomponents were identified by GC-MS present in that spot.In vitro anti-inflammatory activity was performed by human RBC membrane stabilization method. Result: The phytochemical test results obtained indicate that hydro-alcoholic extract of aerial part of Bidens pilosa L. possess alkaloids, tannins, terpenoids and saponins whereas HEA extract possess alkaloids, flavonoids, tannins. Both hydro-alcoholic and HEA extracts were found to be safe up to the dose of 2000 mg/kg BW of the mice. Both extracts showed significant in vitro anti-inflammatory activity in a concentration dependent manner. The GC-MS analysis of HEA extract of aerial parts showed the presence of the sixteen different compounds from partially separated extract from TLC plates. Conclusion: Hydro-alcoholic extract of aerial part of Bidens pilosa L. possess alkaloids, tannins, terpenoids and saponins whereas HEA extract possess alkaloids, flavonoids, tannins. Both hydro-alcoholic and HEA extracts were found to be safe up to the dose of 2000 mg/kg BW of the mice. The GC-MS analysis of HEA extract of aerial parts showed the presence of the sixteen different compounds.

scholarly journals A DESCRIPTIVE STUDY AND IN-VITRO ANTIOXIDANT ACTIVITY OF LEAVES EXTRACTS OF TRIDAX PROCUMBENS LINN

2021 ◽  
Vol 11 (6) ◽  
pp. 1-4
Keyword(s):  
Nitric Oxide ◽  
Antioxidant Activity ◽  
Ascorbic Acid ◽  
Ferric Chloride ◽  
Skin Diseases ◽  
Antioxidant Activities ◽  
Folk Medicine ◽  
Alcoholic Extract ◽  
Tridax Procumbens

Tridax Procumbens Linn is a member of the Asteraceae family. Tridax Procumbens has to be utilized because native medication intended for a number of complaints and problems in humans and animals for thousands of years. It is used widely in Indian conventional remedies for healing of wounds, like anticoagulants, in fungal infection, in diarrhea and dysentery, as an antioxidant, antimicrobial, anti-inflammatory, and immunomodulators. In folk medicine, certain communicable skin diseases are treated by using leaves extract. It's also known as 'Bhringraj,' an ayurvedic drug used to treat liver problems. At least 12,000 people have been separated from their families. These compounds protect plants from pathogens, insects, and herbivores by acting as defensive mechanisms. The aim of the test is to establish the antioxidant potential of the leaves of Tridax Procumbens. The current research is aimed at identifying novel plant directions, and antioxidant activity has been chosen for that reason. Using the maceration procedure, the power of the plant's shade dried leaves was extracted with chloroform water and ethanol. The antioxidant activities of the resulting extracts were evaluated using 2 techniques: nitric oxide scavenging activity and ferric chloride reductive ability. The alcoholic extract in 600 mg/ml and 800 mg/ml and 1000 mg/ml concentration has demonstrated antioxidant activity higher than ascorbic acid (20 mg) by nitric oxide scavenging method. By using a ferric chloride scavenging model, the aqueous and alcoholic extracts at 400 g/ml and 600 g/ml concentrations revealed antioxidant activity near to that of ascorbic acid (20 g).

scholarly journals A DESCRIPTIVE STUDY AND IN-VITRO ANTIOXIDANT ACTIVITY OF LEAVES EXTRACTS OF TRIDAX PROCUMBENS LINN

2021 ◽  
Vol IC1 (1) ◽  
pp. 1-4
Author(s):  
Hemant P. Suryawanshi
Keyword(s):  
Nitric Oxide ◽  
Antioxidant Activity ◽  
Ascorbic Acid ◽  
Ferric Chloride ◽  
Skin Diseases ◽  
Antioxidant Activities ◽  
Folk Medicine ◽  
Alcoholic Extract ◽  
Tridax Procumbens

Tridax Procumbens Linn is a member of the Asteraceae family. Tridax Procumbens has to be utilized because native medication intended for a number of complaints and problems in humans and animals for thousands of years. It is used widely in Indian conventional remedies for healing of wounds, like anticoagulants, in fungal infection, in diarrhea and dysentery, as an antioxidant, antimicrobial, anti-inflammatory, and immunomodulators. In folk medicine, certain communicable skin diseases are treated by using leaves extract. It's also known as 'Bhringraj,' an ayurvedic drug used to treat liver problems. At least 12,000 people have been separated from their families. These compounds protect plants from pathogens, insects, and herbivores by acting as defensive mechanisms. The aim of the test is to establish the antioxidant potential of the leaves of Tridax Procumbens. The current research is aimed at identifying novel plant directions, and antioxidant activity has been chosen for that reason. Using the maceration procedure, the power of the plant's shade dried leaves was extracted with chloroform water and ethanol. The antioxidant activities of the resulting extracts were evaluated using 2 techniques: nitric oxide scavenging activity and ferric chloride reductive ability. The alcoholic extract in 600 mg/ml and 800 mg/ml and 1000 mg/ml concentration has demonstrated antioxidant activity higher than ascorbic acid (20 mg) by nitric oxide scavenging method. By using a ferric chloride scavenging model, the aqueous and alcoholic extracts at 400 g/ml and 600 g/ml concentrations revealed antioxidant activity near to that of ascorbic acid (20 g).

scholarly journals THE DEVELOPMENT AND VALIDATION OF THE METHOD TO QUANTIFY THE AMOUNT OF PHENOLIC ACIDS IN AERIAL PARTS OF ZIZIPHORA CLINOPODIOIDES LAM.

2019 ◽  
pp. 161-168 ◽  
Author(s):  
Valeriya Yur'yevna Andreeva ◽  
Galina Il'inichna Kalinkina ◽  
Valeriya Vladimirovna Li
Keyword(s):  
Quantitative Determination ◽  
Phenolic Acids ◽  
Aerial Part ◽  
Raw Material ◽  
Alcoholic Extract ◽  
Extraction Temperature ◽  
Aerial Parts ◽  
Highly Sensitive ◽  
Development And Validation

Development and validation of method for quantitative determination of the amount of phenolic acids in the aerial part of the Ziziphora clinopodioides Lam. Objective: to develop and conduct a validation assessment of the method for determining the content of the amount of phenolic acids in the Ziziphora clinopodioides. The method of quantification of phenolic acids equivalent to chlorogenic acid by direct spectrophotometry in aerial parts of the Ziziphora clinopodioides has been developed based on the study of the absorption spectrum of an aqueous-alcoholic extract. The influence of the following factors on the yield of phenolic acids was studied: the nature of the extractant, the ratio of raw material: extractant, the degree of particle fineness, the extraction multiplicity, the extraction temperature; their optimum values were established. The method of quantitative determination of the amount of phenolic acids in the aerial part of the Ziziphora clinopodioides is validated; it has been established that the proposed method is highly sensitive, correct, reproducible and suitable for use in an analytical laboratory based on the data obtained.

scholarly journals Phytochemical screening, antibacterial and allelopathic effects of few invasive plants of Kerala

2018 ◽  
Vol 5 (4) ◽  
pp. 175-181
Author(s):  
Jess Mary James ◽  
C U Geethumol ◽  
Arsha Anilkumar ◽  
G Selvaraj
Keyword(s):  
Invasive Plants ◽  
Alcoholic Extract ◽  
Native Flora ◽  
Cuscuta Reflexa ◽  
Legume Seeds ◽  
Prime Concern ◽  
Tridax Procumbens ◽  
Inhibition Zones ◽  
Allelopathic Effects ◽  
Escherichia Coli Bacteria

Invasive species are often regarded as a threat to native flora. Many of them curtail the normal physiological functioning abilities of the native plants by growing over them, or by producing certain metabolites which control their growth potentials and seed germination abilities. The present study aims to find out the different bioactive compounds like alkaloids and terpenoids responsible for the vast spread of Eupatorium odoratum, Vernonia cinerea, Mikania micrantha, Tridax procumbens, Pilea microphylla and Cuscuta reflexa which are some of the major invasive plants of Kerala. Apart from these negative roles attributed to invasive plants, whether they possessed any beneficial roles was the prime concern of this study. Our study brings to light the allelopathic effects of invasive plants upon legume seeds. Different phytochemicals which are known to produce such effect were present in all these plants. Greatest allelopathic effects were exhibited by C. reflexa and E. odoratum. Against Escherichia coli bacteria, E. odoratum and M. micrantha showed highest zone of inhibition (20 mm, 15 mm) while against Proteus vulgaris bacteria, C. reflexa, M. micrantha and T. procumbens produced inhibition zones of 21 mm, 15 mm and 12 mm. Against Pseudomonas aeruginosa bacteria, C. reflexa, M. micrantha and E. odoratum produced inhibition zones of 16 mm, 13 mm and 12 mm. Alcoholic extract of V. cinerea showed comparatively high inhibition against Staphylococcus aureus bacteria (10 mm). V. cinerea showed inhibitiory effects against E. coli, S. aureus and P. vulgaris (11 mm, 10 mm and 9 mm). Similarly, P. microphylla showed inhibition only against P. vulgaris and P. aeruginosa (10 mm and 8 mm).

In vivo anti-inflammatory and hepatoprotective of aerial part of Silene villosa

Planta Medica ◽  
2016 ◽  
Vol 81 (S 01) ◽  
pp. S1-S381
Author(s):  
HS Yusufoglu ◽  
AI Foudah ◽  
A Alam ◽  
GA Soliman
Keyword(s):  
Aerial Part ◽  
Anti Inflammatory

Antiplasmin Deficiency in Polycythaemia: a Form of Thrombopathy

1961 ◽  
Vol 06 (03) ◽  
pp. 445-461 ◽  
Author(s):  
S. I de Vries ◽  
M. A. J Braat-van Straaten ◽  
E Müller ◽  
M Wettermark
Keyword(s):  
Fibrinolytic Activity ◽  
Alcoholic Extract ◽  
Surgical Interventions ◽  
Fallot's Tetralogy ◽  
Naturally Occurring ◽  
Fallot’S Tetralogy

SummaryA marked fibrinolytic activity could be demonstrated in the blood of 10 patients with polycythaemia. In these cases fibrinolysis was considered the result of a deficiency an antiplasmin. It could be demonstrated that this naturally occurring inhibitor of fibrinolysis is present in normal platelets but is lacking in the patient’s own thrombocytes. This factor is probably attached to the surface of the thrombocytes. It could be removed by repeatedly washing. Lack of antiplasmin is a dysfunction of platelets and a form of thrombopathy. It does not respond on treatment with ACA or prednisone. In primary polycythaemia busulfan (Myleran) was considered to be the treatment of choice, whereas in 1 case of secundary erythrocytosis (Fallot’s tetralogy) the reaction on unroasted peanuts was unmistakable. In 4 more patients an alcoholic extract of peanuts was given, and promising results were obtained in 3 of them. The importance of this “thrombopathic type’ of fibrinolysis has been pointed out especially in view of surgical interventions.

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