scholarly journals Effect of Dopamine, a Human Love Factor, on the Physio-Chemical Properties of Filamentous Green Alga: Spirogyra

2021 ◽  
Vol 8 (3) ◽  
Author(s):  
Aishwarya Khamari ◽  
Akshya K. Mishra ◽  
Samir K. Bhoi ◽  
Monika Khamari
Keyword(s):  
Ventral Tegmental Area ◽  
Green Alga ◽  
Chemical Structure ◽  
Chemical Properties ◽  
Filamentous Algae ◽  
Human Love ◽  
Physico Chemical ◽  
New Compounds ◽  
The Brain ◽  
Lower Group

Dopamine is a hormone & neurotransmitter, occurring in wide verities of animals, including both vertebrates and invertebrates. In chemical structure, it is a phenylethylamine. Dopamine is commonly associated with the pleasure system of the brain, providing the feelings of enjoyment and reinforcement to motivate a process to perform certain activities. It is released (particularly in area such as nucleus accbens and ventral tegmental area) by naturally rewarding experiences such as food sex etc. Since conjugating is such type of activity i.e. it is also manifested in lower group of filamentous algae, it was thought that how these groups of algae respond to dopamine. The effect of dopamine was studied on the physico-chemical properties of Spirogyra and it was observed that the changing the colour to yellow is accomplished by the formation of new compounds (??) needs further investigation.

Chemical structure and physico-chemical properties of agar

Hydrobiologia ◽  
1991 ◽  
Vol 221 (1) ◽  
pp. 137-148 ◽  
Author(s):  
Marc Lahaye ◽  
Cyrille Rochas
Keyword(s):  
Chemical Structure ◽  
Chemical Properties ◽  
Physico Chemical

scholarly journals The Effect of Chitosan on the Chemical Structure, Morphology, and Selected Properties of Polyurethane/Chitosan Composites

Polymers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1205
Author(s):  
Agnieszka Piotrowska-Kirschling ◽  
Joanna Brzeska
Keyword(s):  
Chemical Structure ◽  
Materials Science ◽  
Chemical Properties ◽  
Materials Synthesis ◽  
Physico Chemical ◽  
Structure Morphology ◽  
Basic Parameters ◽  
Properties Of Materials ◽  
The Impact ◽  
Positive Effect

Materials science is an interdisciplinary area of studies. This science focuses on the influence of the physico-chemical properties of materials on their application in human everyday lives. The materials’ synthesis should be developed in accordance with sustainable development. Polyurethanes (PUR) represent a significant consumption of plastic in the world. Modification of PUR, e.g., with polysaccharide of natural origin (chitosan, Chit), should have a positive effect on their functional properties and degradability in the natural environment. The basic parameters affecting the scope and direction of changes are the size and quantity of the chitosan particles. The impact assessment of chitosan on the chemical structure, morphology, thermal properties, crystallinity, mechanical properties, flammability, water sorption, adsorption properties, degradability, and biological activity of PUR/Chit composites (without other additives) is discussed in this article. To the best of our knowledge, recent literature does not contain a study discussing the direct impact of the presence of chitosan in the structure of PUR/Chit composite on its properties, regardless of the intended uses. This paper provides an overview of publications, which presents the results of a study on the effect of adding chitosan in polyurethane/chitosan composites without other additives on the properties of polyurethane.

Modeling Physico-Chemical ADMET Endpoints With Multitask Graph Convolutional Networks

2019 ◽  
Author(s):  
Floriane Montanari ◽  
Lara Kuhnke ◽  
Antonius ter Laak ◽  
Djork-Arné Clevert
Keyword(s):  
Chemical Properties ◽  
Predictive Performance ◽  
Machine Learning Techniques ◽  
Convolutional Network ◽  
Convolutional Networks ◽  
Modeling Methods ◽  
Applied Machine Learning ◽  
Learning Techniques ◽  
Physico Chemical ◽  
New Compounds

Simple physico-chemical properties like logD, solubility or serum albumin binding have a direct impact on the likelihood of success of compounds in clinical trials. Here, we collected all the Bayer in house data related to these properties and applied machine learning techniques to predict them for new compounds. We report that, for the endpoints studied here, a multitask graph convolutional network appears a highly competitive choice. The new model shows increased predictive performance on all endpoints compared to previous modeling methods.<br>

Modeling Physico-Chemical ADMET Endpoints With Multitask Graph Convolutional Networks

2019 ◽  
Author(s):  
Floriane Montanari ◽  
Lara Kuhnke ◽  
Antonius ter Laak ◽  
Djork-Arné Clevert
Keyword(s):  
Chemical Properties ◽  
Predictive Performance ◽  
Machine Learning Techniques ◽  
Convolutional Network ◽  
Convolutional Networks ◽  
Modeling Methods ◽  
Applied Machine Learning ◽  
Learning Techniques ◽  
Physico Chemical ◽  
New Compounds

Simple physico-chemical properties like logD, solubility or serum albumin binding have a direct impact on the likelihood of success of compounds in clinical trials. Here, we collected all the Bayer in house data related to these properties and applied machine learning techniques to predict them for new compounds. We report that, for the endpoints studied here, a multitask graph convolutional network appears a highly competitive choice. The new model shows increased predictive performance on all endpoints compared to previous modeling methods.<br>

scholarly journals Synthesis and structural features of 5-(4-(tert-butyl) phenyl)-4-((R)amino)-4H-1,2,4-triazole-3-thiols

2018 ◽  
pp. 60-65
Author(s):  
I. I. Aksyonova-Seliuk ◽  
O. I. Panasenko ◽  
E. G. Knysh
Keyword(s):  
Chemical Structure ◽  
Chemical Properties ◽  
Biologically Active ◽  
Physical And Chemical Properties ◽  
Tert Butyl ◽  
New Compounds ◽  
Physical And Chemical ◽  
Derivatives Of ◽  
Active Substances ◽  
And Chemical Properties

Chemistry of heterocyclic compounds is one of the most popular sector in organic chemistry. Scientists allocate among them a class of derivatives of 1,2,4-triazole. This class of compounds attracts attention his broad spectrum of biological activity. There are antiviral, anti-inflammatory, anti-tubercular, antimicrobial, antioxidant, actoprotective, anti-cancer and other activities. The derivatives of 1,2,4-triazole have one more important advantage. It is low toxicity. This properties do this class of derivatives promising for researches their chemical structure and biological activity and purposeful search of biologically active substances. The purpose of the work is synthesis of 5-(4-(tert-butyl)phenyl)-4-((R)amino)-4H-1,2,4-triazoles-3-thiols from appropriate ylidene derivatives of 4-amino-5-(4 (tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol and research of their physical and chemical properties. The objects of research were 10 new compounds, derivatives of 4-amino-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol. These compounds are the crystal substances which are odorless, insoluble in water and soluble in organic solvents. Investigation of the physical and chemical properties of this compounds was carried out according to the methods listed in the State Pharmacopoeia of Ukraine. The melting temperature of synthesized compounds was determined by device OptiMelt Stanford Research Systems MPA100. The structure of the compound was confirmed by 1H-NMR spectroscopy (Mercury 400) and gas chromatography-mass spectrometry (Agilent 1260 Infinity HPLC). 10 new compounds, derivatives of 4-amino-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazoles-3-thiol, were synthesized in a study. The chemical structure of the new compounds was confirmed by modern instrumental methods of analysis. Results of the done work can be use in the future search of biologically active substances.

scholarly journals Interactions between Cocoa Husk Catechin and Casein Micelles and their Impact on Physico-chemical Properties

2021 ◽  
pp. 21-33
Author(s):  
Premy Puspitawati Rahayu ◽  
Abdul Manab ◽  
Manik Eirry Sawitri ◽  
Ria Dewi Andriani ◽  
Mulia Winirsya Apriliyani ◽  
...  
Keyword(s):  
Particle Size ◽  
Fourier Transform ◽  
Chemical Structure ◽  
Protein Profile ◽  
Chemical Properties ◽  
Electrophoretic Analysis ◽  
Animal Science ◽  
Physico Chemical ◽  
Infra Red ◽  
Microscopy Analysis

Aims: The purpose of this research was to investigate the influence of physicochemical properties of interaction casein with different concentration catechin sources of the cocoa husk. Study design: Casein was added catechin with various concentration treatments (0 (control), 20, 40 and 60 (μg/ml)). Place and Duration of Study: This study was conducted between April until August 2020 at the Faculty of Animal Science, Universitas Brawijaya. Methodology: Casein was added catechin with various concentration treatments (0, 20, 40 and 60 (μg/ml)). An analysis is carried out to determine interaction using UV-Vis detection, chemical structure using Fourier Transform Infra-Red, microscopy analysis by Scanning Electron Microscopy, particle size by Zetasizer Nano Series Software Version 7.01, Malvern Instrument and electrophoretic analysis. Results: The interaction between casein and catechin was investigated by the method of UV-Vis detection and chemical structure analysis by Fourier Transform Infra-Red showed that it was indicated that catechin could detected in casein. It is similar with recent research. The interaction of casein and catechin showed to decrease the particle size and showed on microscopy analysis. Protein profile showed to increase the molecular weight with the addition of catechin, it can be indicated that presence interaction both on casein with catechin. Conclusion: Casein interacted with catechins 60 µg/ml was able to increase casein stability, maintain nano size, casein components were still detected in the protein profile, the resulting microstructure looked compact and functional groups of bioactive compounds were still detected using Fourier Transform Infra-Red.

scholarly journals Synthesis, physico-chemical properties of derivatives 3-(alkylthio)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-4-amine

2018 ◽  
pp. 50-54
Author(s):  
A. A. Safonov
Keyword(s):  
Chemical Properties ◽  
High Reactivity ◽  
Pharmacological Activities ◽  
High Biological Activity ◽  
Physico Chemical ◽  
Low Toxicity ◽  
Pharmacologically Active ◽  
Pharmacologically Active Compounds ◽  
New Compounds ◽  
Derivatives Of

Recently, the search for new compounds with high biological activity, which can be the basis for potential drugs, becomes topical for world scientists. A heterocyclic compound cause particular interest in this area as highly pharmacologically active compounds. Scientists extends interest due to the low toxicity and high reactivity 1,2,4-triazole of the system. It is proved that the combination of triazole nucleus with other heterocyclic systems, especially in the fifth position, causes increased biological effect, and, sometimes, the appearance of new pharmacological activities. The aim of the work was the synthesis of 3-(alkylthio)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-4-amines and their derivatives, study of their physico-chemical properties. A series of new derivatives of the compounds 4-amino-5-R-1,2,4-triazole-3-thione (3-(alkylthio)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-4-amines and N-R-idene)-3-(nonylthio)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazol-4-amines) was synthesizes. The structure of compounds is set with modern physico-chemical methods of analysis (elemental analysis, 1H-NMR spectroscopy). Individuality is proved by HPLC-MS.

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