scholarly journals Cardiac autonomic neuropathy in patients with diabetes mellitus: risk factors, diagnosis and cure (literature review).

2018 ◽  
Vol 193 (7) ◽  
pp. 20-30
Author(s):  
I.S. Nurakhmedova ◽  
◽  
A.A. Nurbekova
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Literature Review ◽  
Autonomic Neuropathy ◽  
Cardiac Autonomic Neuropathy ◽  
Patients With Diabetes ◽  
Diabetes Mellitus Risk

scholarly journals Risk factors cardiovascular autonomi c neuropathy in type 2 diabetes mellitus

2018 ◽  
Vol 23 (4) ◽  
pp. 309-313
Author(s):  
O.A. Stepura ◽  
B.N. Mankovsky
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Autonomic Neuropathy ◽  
Cardiac Autonomic Neuropathy ◽  
Type 2 Dm ◽  
Patients With Diabetes ◽  
Cardiovascular Tests

Cardiac autonomic neuropathy (CAN) is one of the lifethreatening complications of diabetes mellitus (DM), increasing the mortality of patients with diabetes, cardiovascular morbidity and chronic kidney disease. The aim of this study was to investigate risk factors of CAN in patients with type 2 diabetes mellitus. Materials and methods. We examined 127 patients, 51 men and 76 women with type 2 DM. The diagnosis of CAN was performed by studying the heart rate variability (R-R intervals on the electrocardiogram) based on 5 cardiovascular tests for D. Ewing and the Poly-SpectrumRhythm.NET program module. The diagnosis of CAN was confirmed in patients who had 2 positive tests of 5 and a definite CAN — 3 and more positive of 5.The data analysis by SPSS statistical package version 23.0 for Windows. Results. CAN was diagnosed in 81,9% patients, definite CAN in 55,1% patients with type 2 DM. We found positive correlation between the definite CAN with glomerular filtration rate (OR=7,01, p<0,05) and body mass index (OR=1,69, p<0,05), negative correlation between the definite CAN with age (OR= -2,66, p<0,05), diabetes duration (OR= -2,59, p<0,05) and diastolic blood pressure (OR= -5,07, p<0,05). Conclusion. We found such risk factors for cardiovascular autonomic neuropathy in type 2 DM as age, duration of diabetes, BMI, GFR, DBP, therefore presence of diabetic nephropathy and arterial hypertension. These data can suggest the pathogenetic role of the impairment of autonomic nervous system and somatic nervous damage are different.

scholarly journals A Study of Cardiac Autonomic Neuropathy among Type-II Diabetic Patients

2021 ◽  
pp. 345-352
Author(s):  
B.V. Surendra ◽  
N. S. Muthiah ◽  
M. V. Sailaja ◽  
K. Prabhu
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Autonomic Neuropathy ◽  
Tertiary Care ◽  
Male Gender ◽  
Cardiac Autonomic Neuropathy ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Type Ii ◽  
Duration Of Diabetes

Background: Though very common, CAN is a least understood complication of diabetes which is often under diagnosed. In diabetes mellitus patients, CAN leads to silent myocardial infarction and sudden death. So by identifying CAN early, which is asymptomatic will help to delay or arrest its progression. AIM: To find out the prevalence and the associated risk factors of Cardiac autonomic neuropathy (CAN) among type-II Diabetes Mellitus patients in a tertiary care hospital. Materials & Methods: A total of 273 type-II diabetic participants were selected after taking into consideration of inclusion & exclusion criteria. The prevalence of CAN was assessed by ewings and clarkesnon invasive cardiac autonomic neuropathy reflex tests. The association of risk                  factors with the presence of CAN was analysed by using Pearson’s chi square test.                               Data were analysed by using SPSS 16. The accepted level of significance was set below 0.05 (P<0.05). Results: The prevalence of CAN among type-II diabetic patients in this study was found to be 34%. Prevalence of CAN increased in the participants with male gender, increased age, and increased BMI, increased duration of diabetes, poor glycaemic control,dyslipidimea, smokers and hypertension and it is statistically significant. Conclusion: In this study it is observed that the prevalence of CAN increased with old age, male gender, poor glycemic control, increased duration of diabetes, Dyslipidemia, higher BMI, Hypertension & smoking. So risk factors associated with the CAN be detected and treated at an early stage to further reduce morbidity and mortality.

scholarly journals Faktor Risiko Terjadinya Coronavirus Disease 2019 pada Pasien dengan Komorbid Diabetes Melitus

2021 ◽  
Vol 2 (4) ◽  
pp. 105-112
Author(s):  
Nikma Syalsabiela Fauzia
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Literature Review ◽  
Virus Disease ◽  
Microvascular Complications ◽  
Future Research ◽  
Patients With Diabetes ◽  
Sympathetic Nervous ◽  
Clinical Conditions ◽  
Diabetes Melitus

Corona virus disease 2019 (COVID-19) is an infectious disease severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). The clinical scope of Covid-19 varies, from asymptomatic, mild symptoms, to clinical conditions characterized by acute respiratory failure. The most common comorbidities in patients with COVID-19 were hypertension (HTN) (56.2%), followed by diabetes mellitus (DM) (30.1%), and chronic kidney disease (CKD) (17.5%). Several studies suggest that diabetes is one of the main risk factors for COVID-19. Therefore, this literature review aims to determine the risk factors for the occurrence of COVID-19 in patients with diabetes mellitus so that it can be used as a consideration for controlling risk factors and better treatment of COVID-19 patients with comorbidities. The method used in this research is literature review and literature search is carried out through the NCBI, PubMed, and Google Scholar databases. This research involves as many as 24 library sources from 2020-2021. Several studies have shown that diabetes mellitus is a major risk factor for COVID-19. This condition is associated with several macrovascular and microvascular complications that ultimately impact the patient's survival. Diabetes which is a hyperinflammatory condition that can increase susceptibility to COVID-19 with possible mechanisms of chronic inflammation, hypercoagulable state, and activation of the renin-angiotensin-aldosterone system (RAAS) and dysregulation of the sympathetic nervous system. Future research is urgently needed to provide a better understanding of the pathophysiological mechanisms underlying the association between COVID-19 and diabetes, and their clinical management

scholarly journals Cardiac autonomic neuropathy in diabetes mellitus

2017 ◽  
Vol 6 (1) ◽  
pp. 88 ◽  
Author(s):  
Bijaya K. Behera ◽  
Vishnu K.
Keyword(s):  
Diabetes Mellitus ◽  
Autonomic Neuropathy ◽  
Final Analysis ◽  
Cross Sectional Study ◽  
Cardiac Autonomic Neuropathy ◽  
Diabetic Patients ◽  
College Hospital ◽  
Cross Sectional ◽  
Medical College ◽  
Patients With Diabetes

Background: The present study was conducted with an objective to study the prevalence of cardiac autonomic neuropathy (CAN) in patients with diabetes mellitus (DM) and its relation to duration, severity of DM, patient's age and BMI.Methods: This hospital based prospective study was conducted from August 2015 to September 2017, at M.K.C.G. Medical College Hospital, Berhampur, Odisha, India. Cross sectional study was design. A total number of 100 diagnosed patients of diabetes mellitus who were admitted in hospital or attended on OPD basis were taken for the study. Detailed history, clinical evaluation, laboratory investigations were carried out. The diagnosis of CAN was made by autonomic function tests. The CAN score of each patient was analysed. Database were generated based on age, duration of diabetes, severity of DM and BMI.Results: Out of 100 diabetic patients, 40 patients (23 males and 17 females) were selected for final analysis after excluding conditions causing cardiac autonomic neuropathy other than diabetes mellitus. All the patients were in the age group 21 to 70years. In the present study it was found that 57.5% of patients with DM had CAN and its incidence increased with severity of hyperglycemia, duration of DM, BMI and age of the patient.Conclusions: Cardiac autonomic neuropathy is a common and early complication of DM. Proper history taking to identify the symptoms related to CAN and performing simple autonomic tests in all patients of DM can identify cardiac autonomic neuropathy.

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