Alcoholism and Psychiatric Disorder

1987 ◽  
Vol 21 (1) ◽  
pp. 94-101 ◽  
Author(s):  
Kathryn Peace ◽  
Graham Mellsop
Keyword(s):  
Psychiatric Disorder ◽  
Effective Treatment ◽  
Classification System ◽  
Psychiatric Symptoms ◽  
Treatment Strategies ◽  
Future Research ◽  
The Past ◽  
The Subject ◽  
The Relationship ◽  
Psychiatric Problems

Over the past 50 years the relationship between alcoholism and psychiatric disorders, such as depression, anxiety and schizophrenia, has been the subject of a great deal of research. Psychiatric problems have been seen as both a cause and a result of alcoholism. Whatever the relation between alcoholism and psychiatric disorder is, it may have significance for the development of differentially effective treatment strategies. Several authors have argued that the presence and nature of psychiatric symptoms should form the basis of a classification system for alcoholics. Given the potential rewards of such a system for both understanding the aetiology of alcoholism and developing effective treatment strategies, it is important to have a clear picture of the nature and extent of this relationship. This paper reviews critically the published studies of the association between alcoholism and psychiatric disorder and outlines directions for future research.

scholarly journals Tocopherols and Tocotrienols—Bioactive Dietary Compounds; What Is Certain, What Is Doubt?

2021 ◽  
Vol 22 (12) ◽  
pp. 6222
Author(s):  
Kacper Szewczyk ◽  
Aleksandra Chojnacka ◽  
Magdalena Górnicka
Keyword(s):  
Vitamin E ◽  
Metabolic Disorders ◽  
Tissue Concentration ◽  
Biological Properties ◽  
Biological Role ◽  
Future Research ◽  
The Past ◽  
The Subject ◽  
The Relationship

Tocopherols and tocotrienols are natural compounds of plant origin, available in the nature. They are supplied in various amounts in a diet, mainly from vegetable oils, some oilseeds, and nuts. The main forms in the diet are α- and γ-tocopherol, due to the highest content in food products. Nevertheless, α-tocopherol is the main form of vitamin E with the highest tissue concentration. The α- forms of both tocopherols and tocotrienols are considered as the most metabolically active. Currently, research results indicate also a greater antioxidant potential of tocotrienols than tocopherols. Moreover, the biological role of vitamin E metabolites have received increasing interest. The aim of this review is to update the knowledge of tocopherol and tocotrienol bioactivity, with a particular focus on their bioavailability, distribution, and metabolism determinants in humans. Almost one hundred years after the start of research on α-tocopherol, its biological properties are still under investigation. For several decades, researchers’ interest in the biological importance of other forms of vitamin E has also been growing. Some of the functions, for instance the antioxidant functions of α- and γ-tocopherols, have been confirmed in humans, while others, such as the relationship with metabolic disorders, are still under investigation. Some studies, which analyzed the biological role and mechanisms of tocopherols and tocotrienols over the past few years described new and even unexpected cellular and molecular properties that will be the subject of future research.

Policing the Subject: Confessional Absolutism and Communal Autonomy in Eighteenth-Century Austria

2009 ◽  
Vol 40 ◽  
pp. 71-84
Author(s):  
Regina Pörtner
Keyword(s):  
Eighteenth Century ◽  
Early Modern ◽  
Central Europe ◽  
Western Europe ◽  
Future Research ◽  
The Political ◽  
Habsburg Monarchy ◽  
The Past ◽  
The Subject ◽  
The Relationship

If proverbial wisdom predicts longevity to the falsely proclaimed dead, then the paradigm of absolutism and its confessional variant must surely be considered a prime example. Having drawn intense fire from scholars of Western Europe over the past two decades, the concept of absolutism has recently been given a fresh lease of life by research, exploring and, to some extent, vindicating its applicability in the context of seventeenth- and eighteenth-century Central Europe. Given the evolutionary nature of the making of the early modern Austrian-Habsburg monarchy, the complexity of its constitutional, religious, and ethnic makeup, and the waywardness of some of its governing personnel, it seems doubtful if future research will ever be able to satisfactorily clarify the relationship between the political aspirations of individual Austrian rulers, among whom Ferdinand II arguably made the most serious bid for absolute rule, and the practice of negotiated power that characterized the normal state of relations between the Crown and the monarchy's estates.

ON "PLASTIC" WAVES IN SOLIDS

1959 ◽  
Vol 37 (9) ◽  
pp. 1017-1035 ◽  
Author(s):  
John M. Bowsher
Keyword(s):  
Theoretical Study ◽  
Short Review ◽  
Future Research ◽  
Past Work ◽  
The Past ◽  
Engineering Significance ◽  
The Subject

The study of the propagation of "plastic" waves in solids has reached a stage where it is necessary to consider which direction future research should take. In the past 90 or so years many experiments, mostly designed to elucidate certain points of engineering significance, and a few attempts at a theoretical study have cast some light on the subject and revealed it as one of formidable difficulty.Nearly all the experiments have of necessity relied on rather dubious theories for their interpretation, and part of the present paper will be devoted to a description of an apparatus which gives results capable of being interpreted with a very minimum of theory. The remainder of the paper is devoted to a short review of past work with particular emphasis on basic phenomena and to a brief discussion on the most pressing problems still remaining. The experiments described in the present paper bring to light a factor in the propagation of "plastic" waves that seems to have been overlooked in previous work.

New Agendas for Special Education Policy: What the National Reports Haven't Said

1987 ◽  
Vol 53 (4) ◽  
pp. 295-299 ◽  
Author(s):  
Marleen Pugach ◽  
Mara Sapon-Shevin
Keyword(s):  
Special Education ◽  
Education Policy ◽  
Educational Reform ◽  
Special Focus ◽  
Special Education Policy ◽  
The Past ◽  
The Subject ◽  
The Impact ◽  
The Relationship

The calls for educational reform that have dominated the professional and lay literature for the past few years have been decidedly silent in discussing the role of special education either as a contributor or a solution to the problems being raised. As an introduction to this “Special Focus” on the relationship between general educational reform and special education, this article summarizes some of the more prominent reports with regard to their treatment (and nontreatment) of special education. The impact of proposed reforms for the conceptualization and operation of special education is the subject of the five articles that follow.

Fire, people and ecosystem change in Pleistocene Australia

2016 ◽  
Vol 64 (8) ◽  
pp. 643 ◽  
Author(s):  
Christopher N. Johnson
Keyword(s):  
Fire Regimes ◽  
Ecosystem Change ◽  
Future Research ◽  
Cascading Effects ◽  
Continental Scale ◽  
The Past ◽  
The 1960S ◽  
Relationship Of ◽  
The Impact ◽  
The Relationship

Since the 1960s, Australian scientists have speculated on the impact of human arrival on fire regimes in Australia, and on the relationship of landscape fire to extinction of the Pleistocene megafauna of Australia. These speculations have produced a series of contrasting hypotheses that can now be tested using evidence collected over the past two decades. In the present paper, I summarise those hypotheses and review that evidence. The main conclusions of this are that (1) the effects of people on fire regimes in the Pleistocene were modest at the continental scale, and difficult to distinguish from climatic controls on fire, (2) the arrival of people triggered extinction of Australia’s megafauna, but fire had little or no role in the extinction of those animals, which was probably due primarily to hunting and (3) megafaunal extinction is likely to have caused a cascade of changes that included increased fire, but only in some environments. We do not yet understand what environmental factors controlled the strength and nature of cascading effects of megafaunal extinction. This is an important topic for future research.

scholarly journals Antithrombotic Treatment After Coronary Intervention: Agreement and Controversy

2020 ◽  
Vol 15 ◽  
Author(s):  
Tamara García Camarero ◽  
José M de la Torre Hernández
Keyword(s):  
Percutaneous Coronary Intervention ◽  
Treatment Strategies ◽  
Coronary Intervention ◽  
New Drugs ◽  
Antithrombotic Treatment ◽  
The Past ◽  
Percutaneous Coronary ◽  
The Subject ◽  
Clinical Conditions ◽  
Combination Regimens

Percutaneous revascularisation has evolved dramatically in the past few decades. The approach to the management of ischaemic heart disease has changed due to the development of new devices and techniques as well as the availability of new drugs and treatment strategies. Its use in combination with antiplatelet therapies has been essential to protect against stent thrombosis. The length of time this combination therapy is used has been modified in recent years and has been the subject of extensive research. The effect of prolonging the time it is taken or shortening it has been evaluated in different clinical conditions. In practice, the decisions regarding antithrombotic therapy after percutaneous coronary intervention are informed by the patient’s profile and the characteristics of the procedures performed. In this article, we review the use of antiplatelet/anticoagulant therapy after percutaneous coronary intervention focusing on trials and guidelines addressing variable durations for combination regimens and the alternatives.

I. The Augustan Historian

1974 ◽  
Vol 8 ◽  
pp. 5-7
Keyword(s):  
Nazi Germany ◽  
The Political ◽  
New Order ◽  
The Past ◽  
Ab Urbe Condita ◽  
The Future ◽  
The Subject ◽  
The Relationship

During the past forty years the dominant preoccupation of scholars writing on Livy has been the relationship between the historian and the emperor Augustus, and its effects on the Ab Urbe Condita. Tacitus’ testimony that the two were on friendly terms, and Suetonius’ revelation that Livy found time to encourage the historical studies of the future emperor Claudius, appeared to have ominous overtones to scholars writing against the political backcloth of Nazi Germany and Fascist Italy. Though the subject had not been wholly ignored previously, the success of the German cultural propaganda-machine stimulated a spate of approving or critical treatments. While some were hailing Livy as the historian whose work signalled and glorified the new order, others following a similar interpretation were markedly scathing.

scholarly journals Operant Matching as a Nash Equilibrium of an Intertemporal Game

2009 ◽  
Vol 21 (10) ◽  
pp. 2755-2773 ◽  
Author(s):  
Yonatan Loewenstein ◽  
Drazen Prelec ◽  
H. Sebastian Seung
Keyword(s):  
Nash Equilibrium ◽  
Matching Law ◽  
Single Subject ◽  
Multiple Selves ◽  
The Past ◽  
Aggregate Behavior ◽  
The Subject ◽  
Individual Choices ◽  
The Relationship ◽  
Mutual Defection

Over the past several decades, economists, psychologists, and neuroscientists have conducted experiments in which a subject, human or animal, repeatedly chooses between alternative actions and is rewarded based on choice history. While individual choices are unpredictable, aggregate behavior typically follows Herrnstein's matching law: the average reward per choice is equal for all chosen alternatives. In general, matching behavior does not maximize the overall reward delivered to the subject, and therefore matching appears inconsistent with the principle of utility maximization. Here we show that matching can be made consistent with maximization by regarding the choices of a single subject as being made by a sequence of multiple selves—one for each instant of time. If each self is blind to the state of the world and discounts future rewards completely, then the resulting game has at least one Nash equilibrium that satisfies both Herrnstein's matching law and the unpredictability of individual choices. This equilibrium is, in general, Pareto suboptimal, and can be understood as a mutual defection of the multiple selves in an intertemporal prisoner's dilemma. The mathematical assumptions about the multiple selves should not be interpreted literally as psychological assumptions. Human and animals do remember past choices and care about future rewards. However, they may be unable to comprehend or take into account the relationship between past and future. This can be made more explicit when a mechanism that converges on the equilibrium, such as reinforcement learning, is considered. Using specific examples, we show that there exist behaviors that satisfy the matching law but are not Nash equilibria. We expect that these behaviors will not be observed experimentally in animals and humans. If this is the case, the Nash equilibrium formulation can be regarded as a refinement of Herrnstein's matching law.

Teacher Leadership

2015 ◽  
pp. 257-282 ◽  
Author(s):  
Servet Özdemir ◽  
Ali Çağatay Kılınç
Keyword(s):  
School Improvement ◽  
Teacher Leadership ◽  
School Context ◽  
Important Variable ◽  
Future Research ◽  
Leadership Roles ◽  
The Past ◽  
Research Areas ◽  
Factors Influencing ◽  
The Relationship

This chapter focuses on teacher leadership, an important variable in the classroom and school improvement literature. The concept of teacher leadership has attracted increased attention in the past two decades. Teachers are assuming more responsibility for leadership roles and functions within schools. Despite the considerable amount of scholarly effort and time spent on investigating the teacher leadership concept, less is known about how it flourishes in the school context and how it relates to classroom and school improvement. Therefore, this chapter tries to shed some light on the teacher leadership concept and discusses its meaning, teacher leadership roles, factors influencing teacher leadership, the relationship between teacher leadership and classroom and school improvement, and future research areas on teacher leadership. Offering a framework for teacher leadership, this chapter is expected to contribute well to the guidance of further research on teacher leadership.

Monoamines and CSF: relevance to neuropsychiatric disorders

1992 ◽  
Vol 4 (3) ◽  
pp. 47-51
Author(s):  
W.M.A. Verhoeven
Keyword(s):  
Homovanillic Acid ◽  
Neuropsychiatric Disorders ◽  
Endogenous Depression ◽  
Research Strategy ◽  
Future Research ◽  
Monoamine Metabolites ◽  
The Past ◽  
Hydroxyindoleacetic Acid ◽  
Functional Psychopathology ◽  
The Relationship

SummaryOver the past 25 years much effort has been put into the research of the relationship between neuropsychiatric disorders and the concentrations of CSF-monoamine metabolites. Most of this research has beenfocused on the relation between CSF-concentrations of 5-hydroxyindoleacetic acid (5-HIAA) and homovanillic acid (HVA) and specific symptomatological entities, particularly schizophrenia, Alzheimer's dementia and endogenous depression. It appeared that specific relations between diseases and CSF-concentrations of monoamine metabolites cannot be longer maintained and that a more functional psychopathology should be considered as the future research strategy.

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